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The map label for this gene is katA [H]

Identifier: 148828105

GI number: 148828105

Start: 1516932

End: 1518458

Strand: Direct

Name: katA [H]

Synonym: CGSHiGG_08205

Alternate gene names: 148828105

Gene position: 1516932-1518458 (Clockwise)

Preceding gene: 148828100

Following gene: 148828115

Centisome position: 80.38

GC content: 42.11

Gene sequence:

>1527_bases
ATGAGTTCTCAATGTCCTTTCTCGCACTTAGCTGCAACAAACTTAACAATGGGTAACGGTGCACCCGTTGCTGATAACCA
AAACAGCTTAACAGCTGGTCCGCGTGGTCCATTACTTGCACAAGATTTATGGCTTAACGAAAAATTAGCTGATTTCGTAC
GTGAAGTGATCCCAGAGCGTCGTATGCACGCTAAAGGTTCTGGTGCATTTGGTACTTTTACTGTCACACACGATATTACT
AAATATACTCGTGCAAAAATTTTTAGTGAAGTGGGTAAAAAAACGGAAATGTTCGCACGTTTTACCACCGTGGCAGGCGA
ACGTGGTGCAGCAGATGCTGAGCGTGATATTCGTGGTTTTGCATTAAAATTCTATACTGAAGAAGGTAACTGGGATTTAG
TAGGTAACAATACGCCAGTATTCTTCTTACGTGATCCACGTAAATTCCCAGATTTAAATAAAGCAGTAAAACGTGATCCT
CGCACTAATATGCGTTCAGCAACTAATAACTGGGATTTCTGGACATTATTACCAGAAGCATTACACCAAGTCACTGTTGT
AATGAGTGATCGTGGTATTCCAGCAAGTTATCGTCATATGCACGGTTTCGGTTCTCACACTTATAGTTTCTGGAATGAAG
CGGGCGAACGTTTTTGGGTAAAATTCCACTTCCATACACAACAAGGCATCAAAAACTTAACTGATGCAGAAGCGGCTGCA
GTCATCGCAAATGATCGTGAAAGCCATCAACGTGATTTATATGAAGCGATTGAACGTGGTGATTTCCCTAAATGGACATT
ATTTGTACAAGTTATGTCAGAAGCAGATGCGGAAAAAGTGCCTTATCATCCGTTCGACTTAACTAAAGTATGGCCGAAAA
AAGACTATCCATTAATTGAAGTCGGCGAGTTTGAATTAAACCGTAACCCAGAAAACTTCTTCGCTGATGTAGAACAATCT
GCATTTGCACCAAGTAACTTGGTTCCGGGTATTGGCGCAAGTCCTGACAGAATGTTACAAGCTCGTTTATTTAACTATGC
GGATGCACAACGTTACCGTTTAGGTGTGAACTACCGTCAAATTCCAGTAAACCGTCCACGTTGCCCAGTTCATAGCAACC
AACGTGATGGTCAAGGTCGTGTAGATGGTAATTACGGTAGCTTGCCACACTACGAGCCAAACAGCTTTAGCCAATGGCAA
CAACAACCAGACTTTGCTGAACCACCACTTCGTATCAACGGAGATGCAACACACTGGGATTATCGTAACGATGATAACGA
TTACTTCAGCCAACCTCGTGCATTATTTAATTTAATGAATGCAGAGCAAAAACAAGCATTATTCAACAACACGGCAGCAG
CAATGGGCGATGCACCTGATTTCATCAAATATCGTCATATTCGTAACTGTCACTGGTGTGATGCCGCATACGGTGAAGGC
GTTGCGAAAGCATTAGGTTTAACCGTTGAAGATGCATTAAAAGCTCGTGATACTGATCCTGCATTAGGTCAAGGTGGATT
GTTATAA

Upstream 100 bases:

>100_bases
GATTAATTTAATAGATTTCGATTGTTTAAACCTTTCTATATGATACGCAAGAAATTCATTTCAACCTAACTAAATTTATT
AACTTTACAAGGAGTCTACA

Downstream 100 bases:

>100_bases
TCTTTTGAGTTTATTATTTTAAATAAATAATAGTAGTAATGAATCTGCACCCAAAAGTTAGACTAAGGTTTAATCAATTT
GGATGCAGATTTTTTTTAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MSSQCPFSHLAATNLTMGNGAPVADNQNSLTAGPRGPLLAQDLWLNEKLADFVREVIPERRMHAKGSGAFGTFTVTHDIT
KYTRAKIFSEVGKKTEMFARFTTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFLRDPRKFPDLNKAVKRDP
RTNMRSATNNWDFWTLLPEALHQVTVVMSDRGIPASYRHMHGFGSHTYSFWNEAGERFWVKFHFHTQQGIKNLTDAEAAA
VIANDRESHQRDLYEAIERGDFPKWTLFVQVMSEADAEKVPYHPFDLTKVWPKKDYPLIEVGEFELNRNPENFFADVEQS
AFAPSNLVPGIGASPDRMLQARLFNYADAQRYRLGVNYRQIPVNRPRCPVHSNQRDGQGRVDGNYGSLPHYEPNSFSQWQ
QQPDFAEPPLRINGDATHWDYRNDDNDYFSQPRALFNLMNAEQKQALFNNTAAAMGDAPDFIKYRHIRNCHWCDAAYGEG
VAKALGLTVEDALKARDTDPALGQGGLL

Sequences:

>Translated_508_residues
MSSQCPFSHLAATNLTMGNGAPVADNQNSLTAGPRGPLLAQDLWLNEKLADFVREVIPERRMHAKGSGAFGTFTVTHDIT
KYTRAKIFSEVGKKTEMFARFTTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFLRDPRKFPDLNKAVKRDP
RTNMRSATNNWDFWTLLPEALHQVTVVMSDRGIPASYRHMHGFGSHTYSFWNEAGERFWVKFHFHTQQGIKNLTDAEAAA
VIANDRESHQRDLYEAIERGDFPKWTLFVQVMSEADAEKVPYHPFDLTKVWPKKDYPLIEVGEFELNRNPENFFADVEQS
AFAPSNLVPGIGASPDRMLQARLFNYADAQRYRLGVNYRQIPVNRPRCPVHSNQRDGQGRVDGNYGSLPHYEPNSFSQWQ
QQPDFAEPPLRINGDATHWDYRNDDNDYFSQPRALFNLMNAEQKQALFNNTAAAMGDAPDFIKYRHIRNCHWCDAAYGEG
VAKALGLTVEDALKARDTDPALGQGGLL
>Mature_507_residues
SSQCPFSHLAATNLTMGNGAPVADNQNSLTAGPRGPLLAQDLWLNEKLADFVREVIPERRMHAKGSGAFGTFTVTHDITK
YTRAKIFSEVGKKTEMFARFTTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFLRDPRKFPDLNKAVKRDPR
TNMRSATNNWDFWTLLPEALHQVTVVMSDRGIPASYRHMHGFGSHTYSFWNEAGERFWVKFHFHTQQGIKNLTDAEAAAV
IANDRESHQRDLYEAIERGDFPKWTLFVQVMSEADAEKVPYHPFDLTKVWPKKDYPLIEVGEFELNRNPENFFADVEQSA
FAPSNLVPGIGASPDRMLQARLFNYADAQRYRLGVNYRQIPVNRPRCPVHSNQRDGQGRVDGNYGSLPHYEPNSFSQWQQ
QPDFAEPPLRINGDATHWDYRNDDNDYFSQPRALFNLMNAEQKQALFNNTAAAMGDAPDFIKYRHIRNCHWCDAAYGEGV
AKALGLTVEDALKARDTDPALGQGGLL

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=473, Percent_Identity=52.6427061310782, Blast_Score=502, Evalue=1e-142,
Organism=Escherichia coli, GI48994891, Length=497, Percent_Identity=42.6559356136821, Blast_Score=355, Evalue=3e-99,
Organism=Caenorhabditis elegans, GI71998444, Length=450, Percent_Identity=51.1111111111111, Blast_Score=464, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI25151141, Length=451, Percent_Identity=49.2239467849224, Blast_Score=446, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI25147792, Length=451, Percent_Identity=49.0022172949002, Blast_Score=445, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6320462, Length=482, Percent_Identity=47.3029045643153, Blast_Score=402, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6321525, Length=529, Percent_Identity=36.1058601134215, Blast_Score=303, Evalue=4e-83,
Organism=Drosophila melanogaster, GI17981717, Length=477, Percent_Identity=47.5890985324948, Blast_Score=448, Evalue=1e-126,
Organism=Drosophila melanogaster, GI19920968, Length=476, Percent_Identity=44.5378151260504, Blast_Score=416, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 57590; Mature: 57459

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQCPFSHLAATNLTMGNGAPVADNQNSLTAGPRGPLLAQDLWLNEKLADFVREVIPER
CCCCCCCHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHH
RMHAKGSGAFGTFTVTHDITKYTRAKIFSEVGKKTEMFARFTTVAGERGAADAERDIRGF
HHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHCCCEE
ALKFYTEEGNWDLVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNMRSATNNWDFWTLLPEA
EEEEEEECCCEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCHHHCCCCCCHHHHHHHH
LHQVTVVMSDRGIPASYRHMHGFGSHTYSFWNEAGERFWVKFHFHTQQGIKNLTDAEAAA
HHHEEEEEECCCCCHHHHHHCCCCCHHHHHHHHCCCEEEEEEEEEHHHHHHHHHHHHHHE
VIANDRESHQRDLYEAIERGDFPKWTLFVQVMSEADAEKVPYHPFDLTKVWPKKDYPLIE
EEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEE
VGEFELNRNPENFFADVEQSAFAPSNLVPGIGASPDRMLQARLFNYADAQRYRLGVNYRQ
ECCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEEECCCEEE
IPVNRPRCPVHSNQRDGQGRVDGNYGSLPHYEPNSFSQWQQQPDFAEPPLRINGDATHWD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEECCCCCCCC
YRNDDNDYFSQPRALFNLMNAEQKQALFNNTAAAMGDAPDFIKYRHIRNCHWCDAAYGEG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHCCCCCCCCCHHHHH
VAKALGLTVEDALKARDTDPALGQGGLL
HHHHHCCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSQCPFSHLAATNLTMGNGAPVADNQNSLTAGPRGPLLAQDLWLNEKLADFVREVIPER
CCCCCCHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHH
RMHAKGSGAFGTFTVTHDITKYTRAKIFSEVGKKTEMFARFTTVAGERGAADAERDIRGF
HHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHCCCEE
ALKFYTEEGNWDLVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNMRSATNNWDFWTLLPEA
EEEEEEECCCEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCHHHCCCCCCHHHHHHHH
LHQVTVVMSDRGIPASYRHMHGFGSHTYSFWNEAGERFWVKFHFHTQQGIKNLTDAEAAA
HHHEEEEEECCCCCHHHHHHCCCCCHHHHHHHHCCCEEEEEEEEEHHHHHHHHHHHHHHE
VIANDRESHQRDLYEAIERGDFPKWTLFVQVMSEADAEKVPYHPFDLTKVWPKKDYPLIE
EEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEE
VGEFELNRNPENFFADVEQSAFAPSNLVPGIGASPDRMLQARLFNYADAQRYRLGVNYRQ
ECCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEEECCCEEE
IPVNRPRCPVHSNQRDGQGRVDGNYGSLPHYEPNSFSQWQQQPDFAEPPLRINGDATHWD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEECCCCCCCC
YRNDDNDYFSQPRALFNLMNAEQKQALFNNTAAAMGDAPDFIKYRHIRNCHWCDAAYGEG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCHHHHHHHHCCCCCCCCCHHHHH
VAKALGLTVEDALKARDTDPALGQGGLL
HHHHHCCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8188593; 7542800 [H]