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The map label for this gene is ndk [H]

Identifier: 148828058

GI number: 148828058

Start: 1460470

End: 1460892

Strand: Direct

Name: ndk [H]

Synonym: CGSHiGG_07920

Alternate gene names: 148828058

Gene position: 1460470-1460892 (Clockwise)

Preceding gene: 148828057

Following gene: 148828062

Centisome position: 77.39

GC content: 36.88

Gene sequence:

>423_bases
ATGACAGAAAGAACGTTTTCGATTATTAAACCTGATGCGGTAAAGCGTAATCTAATTGGAGCAATCTTAACTCGTTTTGA
GCAAAATGGCTTTAAAATCATAGCCTCTAAAATGGTACGCCTAACTCGTGAGCAGGCTGAAGGCTTTTATGCAGAGCATC
AAGGCAAAGAATTTTTTGCTCCTTTAGTTGAATATATGATGTCTTCGCCGATAGTGGTTTCTGTTCTTGAAAAAGAAAAT
GCAGTGAAAGATTACCGCACTTTGATTGGTACAACGAATCCAGAAACTGCAGAAGAAGGGACAATTCGTAAAGATTTTGC
ATTAAGTCAGCGTGAGAATTCGGTTCACGGATCAGATAGTATAGAAAATGCAAATCGTGAAATTGCTTATTTCTTTACTG
ATTGTGAAATTTTTGAGCGTTAA

Upstream 100 bases:

>100_bases
TAAATCTAGTAGTGATTTATGGGCTGTTGGGGCGACAGGGATTGGTGTGCAAACTTTAGCAAATTTAATGTTATCAAAAT
CATTGAAGTAAGGAGATATG

Downstream 100 bases:

>100_bases
TTGATAGCAAAAAGCACCTAAAAGTTTTAGGTGCTTTTAAAGTTTTAATGCTTACAAAATTAGACTTTCTTAAGGTTTAT
AGATGAACTCAATTCCTTCA

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MTERTFSIIKPDAVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGFYAEHQGKEFFAPLVEYMMSSPIVVSVLEKEN
AVKDYRTLIGTTNPETAEEGTIRKDFALSQRENSVHGSDSIENANREIAYFFTDCEIFER

Sequences:

>Translated_140_residues
MTERTFSIIKPDAVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGFYAEHQGKEFFAPLVEYMMSSPIVVSVLEKEN
AVKDYRTLIGTTNPETAEEGTIRKDFALSQRENSVHGSDSIENANREIAYFFTDCEIFER
>Mature_139_residues
TERTFSIIKPDAVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGFYAEHQGKEFFAPLVEYMMSSPIVVSVLEKENA
VKDYRTLIGTTNPETAEEGTIRKDFALSQRENSVHGSDSIENANREIAYFFTDCEIFER

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=136, Percent_Identity=46.3235294117647, Blast_Score=131, Evalue=2e-31,
Organism=Homo sapiens, GI66392203, Length=137, Percent_Identity=43.7956204379562, Blast_Score=128, Evalue=1e-30,
Organism=Homo sapiens, GI66392227, Length=137, Percent_Identity=43.7956204379562, Blast_Score=128, Evalue=1e-30,
Organism=Homo sapiens, GI66392205, Length=137, Percent_Identity=43.7956204379562, Blast_Score=128, Evalue=1e-30,
Organism=Homo sapiens, GI4505409, Length=137, Percent_Identity=43.7956204379562, Blast_Score=128, Evalue=1e-30,
Organism=Homo sapiens, GI66392192, Length=137, Percent_Identity=43.7956204379562, Blast_Score=128, Evalue=1e-30,
Organism=Homo sapiens, GI38045913, Length=131, Percent_Identity=44.2748091603053, Blast_Score=127, Evalue=3e-30,
Organism=Homo sapiens, GI4557797, Length=131, Percent_Identity=44.2748091603053, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI4826862, Length=135, Percent_Identity=39.2592592592593, Blast_Score=113, Evalue=6e-26,
Organism=Homo sapiens, GI5031951, Length=134, Percent_Identity=39.5522388059701, Blast_Score=97, Evalue=5e-21,
Organism=Homo sapiens, GI37574614, Length=133, Percent_Identity=32.3308270676692, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI7019465, Length=133, Percent_Identity=32.3308270676692, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI4505413, Length=137, Percent_Identity=35.7664233576642, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI148839372, Length=137, Percent_Identity=34.3065693430657, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI30023828, Length=135, Percent_Identity=31.8518518518519, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788866, Length=138, Percent_Identity=63.0434782608696, Blast_Score=179, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17506807, Length=136, Percent_Identity=44.8529411764706, Blast_Score=132, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6322783, Length=138, Percent_Identity=44.9275362318841, Blast_Score=135, Evalue=3e-33,
Organism=Drosophila melanogaster, GI45549037, Length=135, Percent_Identity=45.9259259259259, Blast_Score=132, Evalue=7e-32,
Organism=Drosophila melanogaster, GI18860097, Length=135, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24645457, Length=137, Percent_Identity=30.6569343065693, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 16021; Mature: 15890

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERTFSIIKPDAVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGFYAEHQGKEFFA
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHCCHHHHH
PLVEYMMSSPIVVSVLEKENAVKDYRTLIGTTNPETAEEGTIRKDFALSQRENSVHGSDS
HHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
IENANREIAYFFTDCEIFER
CCCCCCEEEEEEECCHHHCC
>Mature Secondary Structure 
TERTFSIIKPDAVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGFYAEHQGKEFFA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHCCHHHHH
PLVEYMMSSPIVVSVLEKENAVKDYRTLIGTTNPETAEEGTIRKDFALSQRENSVHGSDS
HHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
IENANREIAYFFTDCEIFER
CCCCCCEEEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA