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The map label for this gene is corC [H]

Identifier: 148827455

GI number: 148827455

Start: 814186

End: 815085

Strand: Direct

Name: corC [H]

Synonym: CGSHiGG_04320

Alternate gene names: 148827455

Gene position: 814186-815085 (Clockwise)

Preceding gene: 148827454

Following gene: 148827456

Centisome position: 43.14

GC content: 37.11

Gene sequence:

>900_bases
ATGAACGACGAACAGCAAAATTCAAACCAATCTGAAAATACGAAAAAACCTTTTTTCCAATCTTTATTCGGTCGCTTTTT
TCAAGGCGAACTAAAAAATCGTGAAGAACTTGTGGAAGTGATTCGCGATTCAGAACAAAACGATCTAATTGATCAAAATA
CGCGTGAAATGATTGAAGGCGTGATGGAAATTGCGGAACTTCGTGTTCGTGATATTATGATTCCTCGTTCACAAATTATT
TTTATTGAAGATCAACAAGATTTAAATACTTGTTTAAACACAATTATTGAATCCGCTCATTCTCGTTTTCCTGTGATTGC
CGATGCCGATGACCGCGATAATATCGTGGGCATTTTGCACGCAAAAGATTTATTAAAATTTTTACGTGAAGATGCCGAAG
CGTTTGATTTATCTTCATTATTGCGCCCCGTCGTGATTGTGCCAGAAAGCAAAAGAGTGGATCGTATGTTAAAAGATTTC
CGCTCAGAGCGTTTCCATATGGCCATTGTGGTGGATGAATTTGGTGCAGTGTCGGGGCTTGTTACTATTGAAGATATTTT
GGAACAAATTGTTGGCGATATTGAAGATGAATTTGATGAAGAAGAGATTGCGGATATTCGTCAGCTTTCTCGTCATACTT
ATGCAGTGCGTGCGCTCACCGATATTGATGATTTCAATGGGCAATTTAATACGGATTTTGATGATGAAGAAGTAGATACC
ATTGGCGGTCTGATTATGCAAACTTTTGGTTATTTACCAAAACGTGGGGAAGAAATTATTTTGAAAAATCTTCAATTTAA
AGTGACTTCTGCAGATAGTCGTCGATTAATTCAACTTCGAGTCACAGTGCCAGATGAACATTTGGCAGAAATGAATAATG
TAGATGAAAAATCTGAATAG

Upstream 100 bases:

>100_bases
GTGCGGTTATTTTTATTGATTTTCCTCTTTTCGCTTTTTGCGATTTTTTCTAAAATGTGATACTTTTTCGCCGTCAATAA
GACATCAAACACAAATCAAT

Downstream 100 bases:

>100_bases
GATTTTATTATCAATTAAATTTATGAATAAATATTTAACTTATTTTATTGCTTTTATATCGGGTTTAGTCGGTGTTTTTG
CCTTTTCGCCATTTGATTAT

Product: magnesium and cobalt efflux protein CorC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNDEQQNSNQSENTKKPFFQSLFGRFFQGELKNREELVEVIRDSEQNDLIDQNTREMIEGVMEIAELRVRDIMIPRSQII
FIEDQQDLNTCLNTIIESAHSRFPVIADADDRDNIVGILHAKDLLKFLREDAEAFDLSSLLRPVVIVPESKRVDRMLKDF
RSERFHMAIVVDEFGAVSGLVTIEDILEQIVGDIEDEFDEEEIADIRQLSRHTYAVRALTDIDDFNGQFNTDFDDEEVDT
IGGLIMQTFGYLPKRGEEIILKNLQFKVTSADSRRLIQLRVTVPDEHLAEMNNVDEKSE

Sequences:

>Translated_299_residues
MNDEQQNSNQSENTKKPFFQSLFGRFFQGELKNREELVEVIRDSEQNDLIDQNTREMIEGVMEIAELRVRDIMIPRSQII
FIEDQQDLNTCLNTIIESAHSRFPVIADADDRDNIVGILHAKDLLKFLREDAEAFDLSSLLRPVVIVPESKRVDRMLKDF
RSERFHMAIVVDEFGAVSGLVTIEDILEQIVGDIEDEFDEEEIADIRQLSRHTYAVRALTDIDDFNGQFNTDFDDEEVDT
IGGLIMQTFGYLPKRGEEIILKNLQFKVTSADSRRLIQLRVTVPDEHLAEMNNVDEKSE
>Mature_299_residues
MNDEQQNSNQSENTKKPFFQSLFGRFFQGELKNREELVEVIRDSEQNDLIDQNTREMIEGVMEIAELRVRDIMIPRSQII
FIEDQQDLNTCLNTIIESAHSRFPVIADADDRDNIVGILHAKDLLKFLREDAEAFDLSSLLRPVVIVPESKRVDRMLKDF
RSERFHMAIVVDEFGAVSGLVTIEDILEQIVGDIEDEFDEEEIADIRQLSRHTYAVRALTDIDDFNGQFNTDFDDEEVDT
IGGLIMQTFGYLPKRGEEIILKNLQFKVTSADSRRLIQLRVTVPDEHLAEMNNVDEKSE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=209, Percent_Identity=32.5358851674641, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI94681046, Length=194, Percent_Identity=35.5670103092784, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40068055, Length=187, Percent_Identity=33.1550802139037, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI40068053, Length=187, Percent_Identity=33.1550802139037, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786879, Length=286, Percent_Identity=64.3356643356643, Blast_Score=352, Evalue=2e-98,
Organism=Escherichia coli, GI87082033, Length=271, Percent_Identity=30.2583025830258, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI145693175, Length=230, Percent_Identity=26.0869565217391, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1788119, Length=230, Percent_Identity=30.4347826086957, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790664, Length=251, Percent_Identity=26.6932270916335, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 34542; Mature: 34542

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDEQQNSNQSENTKKPFFQSLFGRFFQGELKNREELVEVIRDSEQNDLIDQNTREMIEG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
VMEIAELRVRDIMIPRSQIIFIEDQQDLNTCLNTIIESAHSRFPVIADADDRDNIVGILH
HHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEHH
AKDLLKFLREDAEAFDLSSLLRPVVIVPESKRVDRMLKDFRSERFHMAIVVDEFGAVSGL
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCEEEEEEEECCCHHHHH
VTIEDILEQIVGDIEDEFDEEEIADIRQLSRHTYAVRALTDIDDFNGQFNTDFDDEEVDT
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
IGGLIMQTFGYLPKRGEEIILKNLQFKVTSADSRRLIQLRVTVPDEHLAEMNNVDEKSE
HHHHHHHHHCCCCCCCHHHHHHCCEEEEECCCCCEEEEEEEECCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNDEQQNSNQSENTKKPFFQSLFGRFFQGELKNREELVEVIRDSEQNDLIDQNTREMIEG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHH
VMEIAELRVRDIMIPRSQIIFIEDQQDLNTCLNTIIESAHSRFPVIADADDRDNIVGILH
HHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEHH
AKDLLKFLREDAEAFDLSSLLRPVVIVPESKRVDRMLKDFRSERFHMAIVVDEFGAVSGL
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCEEEEEEEECCCHHHHH
VTIEDILEQIVGDIEDEFDEEEIADIRQLSRHTYAVRALTDIDDFNGQFNTDFDDEEVDT
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
IGGLIMQTFGYLPKRGEEIILKNLQFKVTSADSRRLIQLRVTVPDEHLAEMNNVDEKSE
HHHHHHHHHCCCCCCCHHHHHHCCEEEEECCCCCEEEEEEEECCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]