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The map label for this gene is yfbQ [C]

Identifier: 148827439

GI number: 148827439

Start: 798006

End: 799277

Strand: Direct

Name: yfbQ [C]

Synonym: CGSHiGG_04225

Alternate gene names: 148827439

Gene position: 798006-799277 (Clockwise)

Preceding gene: 148827438

Following gene: 148827440

Centisome position: 42.29

GC content: 41.19

Gene sequence:

>1272_bases
ATGCGATTATTCCCAAAATCCGACAAATTAGAACACGTATGTTATGACATTCGCGGACCTGTGCATAAAGAAGCACTACG
CTTAGAAGAAGAAGGCAATAAAATTTTAAAACTAAATATCGGCAACCCAGCCCCTTTCGGCTTTGAAGCACCAGATGAAA
TTTTGGTGGACGTATTGCGTAATTTGCCGTCAGCTCAAGGCTACTGCGATTCAAAAGGGTTATATTCTGCTCGTAAAGCC
ATTGTTCAATATTACCAATCAAAAGGGATTCTCGGCGCGACCGTCAATGATGTGTATATTGGTAACGGCGTCTCTGAGCT
TATCACAATGGCAATGCAAGCACTGCTCAATGATGGCGATGAAGTGCTTGTGCCGATGCCTGATTATCCGCTTTGGACTG
CTGCGGTAACCCTTTCTGGCGGTAAAGCAGTGCATTATCTCTGTGATGAAGAAGCAAATTGGTTCCCTGCTATTGATGAT
ATTAAAGCAAAGGTGAATGCGAAAACGAAAGCGATTGTCATCATCAACCCGAACAACCCAACGGGTGCTGTGTATAGCAA
AGAATTATTACAAGAAATTGTGGAAATCGCGCGTCAAAATAATTTAATTATCTTCGCTGACGAAATCTACGACAAAATTT
TATACGATGGCGCGGTGCATCATCACATTGCCGCACTAGCTCCTGATTTATTAACCGTTACGCTGAATGGGTTATCAAAA
GCTTATCGAGTTGCAGGCTTCCGCCAAGGCTGGATGATTTTGAACGGTCCAAAACATAATGCGAAAGGTTATATTGAAGG
CTTGGATATGCTGGCATCAATGCGTTTATGTGCCAACGTACCAATGCAACATGCAATTCAAACCGCACTTGGTGGCTATC
AAAGTATTAATGAATTTATTTTACCGGGCGGCAGATTACTTGAGCAACGAAACAAAGCCTATGATCTCATCACTCAAATA
CCCGGCATTACTTGCGTGAAACCAATGGGGGCGATGTATATGTTCCCGAAAATTGATGTGAAAAAATTCAATATTCACAG
TGATGAAAAAATGGTGCTGGATTTACTCCGCCAAGAAAAAGTACTACTTGTGCACGGTAAAGGATTTAATTGGCATTCAC
CAGATCACTTCCGTATTGTTACTCTTCCTTATGTGAATCAGCTTGAAGAAGCCATTACAAAGTTAGCAAGATTTTTTGTC
GGATTACCGTCAATAATGAATGCTTTGACAACATTACAAAGGGGACTAAATGTCCCCTTTTTATCGATATAA

Upstream 100 bases:

>100_bases
GACAAAAAATTTTTTTACAAAATCTTTTCAATATTAAAAATTCAGCGTAAATTAACCGCACTTTTCTCGAAAAATTTATT
AGAAACAAAAGGATTTCACT

Downstream 100 bases:

>100_bases
ATATATTGCACTTTCCTTGCGTACTATTATAATAGTGCAAATTTATTTTAGAGGCATTTTATGATACAACAAAAAATCTC
CTTCTCTCTTAGGCGGTGCA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MRLFPKSDKLEHVCYDIRGPVHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEILVDVLRNLPSAQGYCDSKGLYSARKA
IVQYYQSKGILGATVNDVYIGNGVSELITMAMQALLNDGDEVLVPMPDYPLWTAAVTLSGGKAVHYLCDEEANWFPAIDD
IKAKVNAKTKAIVIINPNNPTGAVYSKELLQEIVEIARQNNLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTLNGLSK
AYRVAGFRQGWMILNGPKHNAKGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFILPGGRLLEQRNKAYDLITQI
PGITCVKPMGAMYMFPKIDVKKFNIHSDEKMVLDLLRQEKVLLVHGKGFNWHSPDHFRIVTLPYVNQLEEAITKLARFFV
GLPSIMNALTTLQRGLNVPFLSI

Sequences:

>Translated_423_residues
MRLFPKSDKLEHVCYDIRGPVHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEILVDVLRNLPSAQGYCDSKGLYSARKA
IVQYYQSKGILGATVNDVYIGNGVSELITMAMQALLNDGDEVLVPMPDYPLWTAAVTLSGGKAVHYLCDEEANWFPAIDD
IKAKVNAKTKAIVIINPNNPTGAVYSKELLQEIVEIARQNNLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTLNGLSK
AYRVAGFRQGWMILNGPKHNAKGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFILPGGRLLEQRNKAYDLITQI
PGITCVKPMGAMYMFPKIDVKKFNIHSDEKMVLDLLRQEKVLLVHGKGFNWHSPDHFRIVTLPYVNQLEEAITKLARFFV
GLPSIMNALTTLQRGLNVPFLSI
>Mature_423_residues
MRLFPKSDKLEHVCYDIRGPVHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEILVDVLRNLPSAQGYCDSKGLYSARKA
IVQYYQSKGILGATVNDVYIGNGVSELITMAMQALLNDGDEVLVPMPDYPLWTAAVTLSGGKAVHYLCDEEANWFPAIDD
IKAKVNAKTKAIVIINPNNPTGAVYSKELLQEIVEIARQNNLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTLNGLSK
AYRVAGFRQGWMILNGPKHNAKGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFILPGGRLLEQRNKAYDLITQI
PGITCVKPMGAMYMFPKIDVKKFNIHSDEKMVLDLLRQEKVLLVHGKGFNWHSPDHFRIVTLPYVNQLEEAITKLARFFV
GLPSIMNALTTLQRGLNVPFLSI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=28.0104712041885, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI19263340, Length=376, Percent_Identity=27.1276595744681, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI215599424, Length=376, Percent_Identity=27.1276595744681, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI4885351, Length=448, Percent_Identity=24.5535714285714, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI56713254, Length=191, Percent_Identity=30.3664921465969, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI56713256, Length=191, Percent_Identity=30.3664921465969, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI95147551, Length=172, Percent_Identity=30.8139534883721, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI169881279, Length=172, Percent_Identity=30.8139534883721, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI169881281, Length=129, Percent_Identity=31.7829457364341, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI187936925, Length=374, Percent_Identity=22.7272727272727, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI14211921, Length=374, Percent_Identity=22.7272727272727, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1788627, Length=401, Percent_Identity=77.8054862842893, Blast_Score=665, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=406, Percent_Identity=25.615763546798, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786816, Length=203, Percent_Identity=23.6453201970443, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=380, Percent_Identity=30.7894736842105, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71981209, Length=463, Percent_Identity=24.4060475161987, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=206, Percent_Identity=32.5242718446602, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=206, Percent_Identity=32.5242718446602, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=25.5972696245734, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=243, Percent_Identity=29.2181069958848, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=453, Percent_Identity=26.0485651214128, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6323118, Length=349, Percent_Identity=27.7936962750716, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6322401, Length=364, Percent_Identity=24.1758241758242, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859735, Length=389, Percent_Identity=28.2776349614396, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24641770, Length=460, Percent_Identity=25.8695652173913, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24641760, Length=460, Percent_Identity=25.8695652173913, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24641768, Length=460, Percent_Identity=25.8695652173913, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24641766, Length=460, Percent_Identity=25.8695652173913, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24641764, Length=460, Percent_Identity=25.8695652173913, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI45551451, Length=460, Percent_Identity=25.8695652173913, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28573069, Length=322, Percent_Identity=25.1552795031056, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646114, Length=322, Percent_Identity=25.1552795031056, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573067, Length=322, Percent_Identity=25.1552795031056, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573065, Length=322, Percent_Identity=25.1552795031056, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 47066; Mature: 47066

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFPKSDKLEHVCYDIRGPVHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEILVDVLR
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
NLPSAQGYCDSKGLYSARKAIVQYYQSKGILGATVNDVYIGNGVSELITMAMQALLNDGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCEEECCCHHHHHHHHHHHHHCCCC
EVLVPMPDYPLWTAAVTLSGGKAVHYLCDEEANWFPAIDDIKAKVNAKTKAIVIINPNNP
EEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEEECCCC
TGAVYSKELLQEIVEIARQNNLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTLNGLSK
CCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCHHHHHHHHHCCHHHEEEHHHHHH
AYRVAGFRQGWMILNGPKHNAKGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFI
HHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRNKAYDLITQIPGITCVKPMGAMYMFPKIDVKKFNIHSDEKMVLDLLRQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCEEEECCCCCHHHHHHHHCCCC
VLLVHGKGFNWHSPDHFRIVTLPYVNQLEEAITKLARFFVGLPSIMNALTTLQRGLNVPF
EEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCE
LSI
ECC
>Mature Secondary Structure
MRLFPKSDKLEHVCYDIRGPVHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEILVDVLR
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
NLPSAQGYCDSKGLYSARKAIVQYYQSKGILGATVNDVYIGNGVSELITMAMQALLNDGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCEEECCCHHHHHHHHHHHHHCCCC
EVLVPMPDYPLWTAAVTLSGGKAVHYLCDEEANWFPAIDDIKAKVNAKTKAIVIINPNNP
EEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEEECCCC
TGAVYSKELLQEIVEIARQNNLIIFADEIYDKILYDGAVHHHIAALAPDLLTVTLNGLSK
CCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCHHHHHHHHHCCHHHEEEHHHHHH
AYRVAGFRQGWMILNGPKHNAKGYIEGLDMLASMRLCANVPMQHAIQTALGGYQSINEFI
HHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRNKAYDLITQIPGITCVKPMGAMYMFPKIDVKKFNIHSDEKMVLDLLRQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCEEEECCCCCHHHHHHHHCCCC
VLLVHGKGFNWHSPDHFRIVTLPYVNQLEEAITKLARFFVGLPSIMNALTTLQRGLNVPF
EEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCE
LSI
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]