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The map label for this gene is fdxG [H]

Identifier: 148827167

GI number: 148827167

Start: 458963

End: 461389

Strand: Direct

Name: fdxG [H]

Synonym: CGSHiGG_02495

Alternate gene names: 148827167

Gene position: 458963-461389 (Clockwise)

Preceding gene: 148827166

Following gene: 148827168

Centisome position: 24.32

GC content: 38.73

Gene sequence:

>2427_bases
ATGACAAATAACTGGGTTGATATTAAAAATGCCAACTTAATCATCGTTCAAGGTGGTAACCCTGCAGAAGCCCATCCTGT
TGGCTTCCGTTGGGCAATTGAAGCGAAGAAAAACGGTGCGAAAATCATCGTTATTGATCCGCGTTTTAACCGTACAGCAT
CCGTTGCTGATCTTCATGCGCCAATTCGTTCTGGTTCTGATATTACGTTCTTAATGGGCGTGATCCGTTACCTATTGGAA
ACAAACCAAATTCAACACGAATATGTTAAACACTATACCAACGCATCATTCTTAATTGATGAAGGTTTCAAATTTGAAGA
TGGTTTATTTGTAGGGTATAACGAAGAAAAACGTAACTACGATAAATCTAAATGGAACTACCAATTTGATGAAAATGGTC
ACGCTAAACGTGATATGACATTACAACATCCTCGTTGTGTCATTAACATCTTAAAAGAGCACGTTTCTCGTTATACCCCA
GAAATGGTTGAACGTATTACAGGCGTAAAACAAAAACTCTTCTTACAAATCTGTGAAGAAATTGGTAAAACCTCTGTGCC
AAATAAAACGATGACGCATCTATATGCATTAGGTTTTACAGAGCATTCAATCGGTACACAAAATATTCGCTCAATGGCGA
TAATCCAGTTACTTTTAGGTAATATGGGGATGCCAGGTGGCGGTATTAACGCATTACGCGGACACTCCAATGTGCAAGGT
ACGACAGATATGGGCTTATTGCCAATGTCTTTACCAGGTTATATGCGTTTGCCAAACGATAAAGATACCTCTTACGATCA
ATACATTAACGCAATTACACCAAAAGATATCGTTCCAAACCAAGTGAACTATTATCGTCATACTTCAAAATTCTTTGTTA
GTATGATGAAAACTTTCTACGGAGATAATGCCACTAAGGAAAATGGCTGGGGATTCGATTTCTTACCAAAAGCAGATCGC
CTATATGATCCAATTACTCACGTTAAATTGATGAATGAAGGCAAATTACACGGTTGGATTTTACAAGGTTTTAACGTATT
AAATTCACTACCAAATAAAAATAAAACGTTATCTGGTATGAGTAAACTGAAATACTTAGTCGTTATGGATCCATTACAAA
CTGAATCATCAGAATTTTGGAAAAATTTTGGTGAGTCAAATGATGTAAATCCTGCAGAAATTCAAACAGAAGTTTTCCGT
TTACCAACTACTTGTTTCGCAGAAGAAGAAGGATCAATCGTTAATTCTGGTCGCTGGACTCAATGGCACTGGAAAGGTTG
CGATCAACCGGGAGAAGCCTTACCTGATGTTGATATTCTTTCTATGCTACGCGAAGAAATGCACGAACTTTATAAAAAAG
AGGGTGGACAAGGAATTGAATCTTTTGAAGCGATGACTTGGAATTATGCTCAACCACACTCACCAAGTGCGGTTGAATTA
GCCAAAGAATTAAATGGTTATGCGCTTGAAGATCTTTATGATCCAAACGGTAACTTGATGTACAAGAAAGGTCAATTACT
CAATGGATTTGCACATTTACGTGATGATGGTACAACAACATCAGGTAACTGGTTATATGTTGGTCAATGGACTGAAAAAG
GCAACCAAACTGCTAATCGCGATAATTCAGATCCATCGGGTTTAGGTTGTACTATTGGCTGGGGCTTTGCATGGCCTGCA
AACCGCCGTGTACTTTATAGCCGTGCATCATTAGATATCAATGGTAATCCTTGGGATAAAAACCGCCAATTAATCAAATG
GAACGGTAAAAACTGGAACTGGTTTGATATTGCTGACTACGGTACGCAGCCACCAGGTTCTGATACTGGGCCGTTCATTA
TGTCCGCAGAAGGCGTAGGACGTTTATTTGCCGTTGATAAAATTGCAAATGGCCCAATGCCAGAACACTATGAACCAGTT
GAAAGCCCAATTGATACAAACCCATTTCATCCAAATGTAGTAACCGATCCAACTTTACGTATCTATAAAGAAGATCGTGA
ATTTATTGGTTCAAATAAAGAGTATCCATTTGTAGCAACAACTTATCGTTTAACCGAGCATTTCCACAGCTGGACTGCAC
AATCTGCATTAAATATCATCGCACAACCACAACAATTTGTGGAAATTGGCGAAAAATTAGCGGCAGAAAAAGGCATCCAA
AAAGGCGATATGGTAAAAATTACTTCTCGTCGTGGCTATATTAAAGCAGTCGCCGTGGTTACAAAACGTCTTAAAGATCT
CGAAATTGATGGACGTGTCGTACACCATATAGGTCTTCCAATTCACTGGAATATGAAGGCATTAAATGGCAAAGGTAACC
GTGGATTCTCTACGAATACCTTAACACCATCTTGGGGAGAGGCAATCACGCAAACACCAGAATACAAAACATTCTTGGTA
AATATTGAAAAAGTTGGGGAGGCATAA

Upstream 100 bases:

>100_bases
GTGGATTAGAATGCTCGGTATGGTGCCAGTATGTAACCAAGCGAATACTTGACACGGACCAACGGTAGCAAGTCTTGCTC
CATCATTTGGTCGCGGTGCC

Downstream 100 bases:

>100_bases
TATGGCTGGAACTGCTCAAGGCGTTCAAACGCAAGACGTTATTAAAATCTCCGCAACATCTGGTTTAACACCAGCACCAC
AAGCGAGAGATCATAAAGTT

Product: formate dehydrogenase major subunit

Products: NA

Alternate protein names: Formate dehydrogenase subunit alpha; FDH subunit alpha [H]

Number of amino acids: Translated: 808; Mature: 807

Protein sequence:

>808_residues
MTNNWVDIKNANLIIVQGGNPAEAHPVGFRWAIEAKKNGAKIIVIDPRFNRTASVADLHAPIRSGSDITFLMGVIRYLLE
TNQIQHEYVKHYTNASFLIDEGFKFEDGLFVGYNEEKRNYDKSKWNYQFDENGHAKRDMTLQHPRCVINILKEHVSRYTP
EMVERITGVKQKLFLQICEEIGKTSVPNKTMTHLYALGFTEHSIGTQNIRSMAIIQLLLGNMGMPGGGINALRGHSNVQG
TTDMGLLPMSLPGYMRLPNDKDTSYDQYINAITPKDIVPNQVNYYRHTSKFFVSMMKTFYGDNATKENGWGFDFLPKADR
LYDPITHVKLMNEGKLHGWILQGFNVLNSLPNKNKTLSGMSKLKYLVVMDPLQTESSEFWKNFGESNDVNPAEIQTEVFR
LPTTCFAEEEGSIVNSGRWTQWHWKGCDQPGEALPDVDILSMLREEMHELYKKEGGQGIESFEAMTWNYAQPHSPSAVEL
AKELNGYALEDLYDPNGNLMYKKGQLLNGFAHLRDDGTTTSGNWLYVGQWTEKGNQTANRDNSDPSGLGCTIGWGFAWPA
NRRVLYSRASLDINGNPWDKNRQLIKWNGKNWNWFDIADYGTQPPGSDTGPFIMSAEGVGRLFAVDKIANGPMPEHYEPV
ESPIDTNPFHPNVVTDPTLRIYKEDREFIGSNKEYPFVATTYRLTEHFHSWTAQSALNIIAQPQQFVEIGEKLAAEKGIQ
KGDMVKITSRRGYIKAVAVVTKRLKDLEIDGRVVHHIGLPIHWNMKALNGKGNRGFSTNTLTPSWGEAITQTPEYKTFLV
NIEKVGEA

Sequences:

>Translated_808_residues
MTNNWVDIKNANLIIVQGGNPAEAHPVGFRWAIEAKKNGAKIIVIDPRFNRTASVADLHAPIRSGSDITFLMGVIRYLLE
TNQIQHEYVKHYTNASFLIDEGFKFEDGLFVGYNEEKRNYDKSKWNYQFDENGHAKRDMTLQHPRCVINILKEHVSRYTP
EMVERITGVKQKLFLQICEEIGKTSVPNKTMTHLYALGFTEHSIGTQNIRSMAIIQLLLGNMGMPGGGINALRGHSNVQG
TTDMGLLPMSLPGYMRLPNDKDTSYDQYINAITPKDIVPNQVNYYRHTSKFFVSMMKTFYGDNATKENGWGFDFLPKADR
LYDPITHVKLMNEGKLHGWILQGFNVLNSLPNKNKTLSGMSKLKYLVVMDPLQTESSEFWKNFGESNDVNPAEIQTEVFR
LPTTCFAEEEGSIVNSGRWTQWHWKGCDQPGEALPDVDILSMLREEMHELYKKEGGQGIESFEAMTWNYAQPHSPSAVEL
AKELNGYALEDLYDPNGNLMYKKGQLLNGFAHLRDDGTTTSGNWLYVGQWTEKGNQTANRDNSDPSGLGCTIGWGFAWPA
NRRVLYSRASLDINGNPWDKNRQLIKWNGKNWNWFDIADYGTQPPGSDTGPFIMSAEGVGRLFAVDKIANGPMPEHYEPV
ESPIDTNPFHPNVVTDPTLRIYKEDREFIGSNKEYPFVATTYRLTEHFHSWTAQSALNIIAQPQQFVEIGEKLAAEKGIQ
KGDMVKITSRRGYIKAVAVVTKRLKDLEIDGRVVHHIGLPIHWNMKALNGKGNRGFSTNTLTPSWGEAITQTPEYKTFLV
NIEKVGEA
>Mature_807_residues
TNNWVDIKNANLIIVQGGNPAEAHPVGFRWAIEAKKNGAKIIVIDPRFNRTASVADLHAPIRSGSDITFLMGVIRYLLET
NQIQHEYVKHYTNASFLIDEGFKFEDGLFVGYNEEKRNYDKSKWNYQFDENGHAKRDMTLQHPRCVINILKEHVSRYTPE
MVERITGVKQKLFLQICEEIGKTSVPNKTMTHLYALGFTEHSIGTQNIRSMAIIQLLLGNMGMPGGGINALRGHSNVQGT
TDMGLLPMSLPGYMRLPNDKDTSYDQYINAITPKDIVPNQVNYYRHTSKFFVSMMKTFYGDNATKENGWGFDFLPKADRL
YDPITHVKLMNEGKLHGWILQGFNVLNSLPNKNKTLSGMSKLKYLVVMDPLQTESSEFWKNFGESNDVNPAEIQTEVFRL
PTTCFAEEEGSIVNSGRWTQWHWKGCDQPGEALPDVDILSMLREEMHELYKKEGGQGIESFEAMTWNYAQPHSPSAVELA
KELNGYALEDLYDPNGNLMYKKGQLLNGFAHLRDDGTTTSGNWLYVGQWTEKGNQTANRDNSDPSGLGCTIGWGFAWPAN
RRVLYSRASLDINGNPWDKNRQLIKWNGKNWNWFDIADYGTQPPGSDTGPFIMSAEGVGRLFAVDKIANGPMPEHYEPVE
SPIDTNPFHPNVVTDPTLRIYKEDREFIGSNKEYPFVATTYRLTEHFHSWTAQSALNIIAQPQQFVEIGEKLAAEKGIQK
GDMVKITSRRGYIKAVAVVTKRLKDLEIDGRVVHHIGLPIHWNMKALNGKGNRGFSTNTLTPSWGEAITQTPEYKTFLVN
IEKVGEA

Specific function: Allows to use formate as major electron donor during anaerobic respiration. Subunit alpha possibly forms the active site [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868719, Length=806, Percent_Identity=63.8957816377171, Blast_Score=1116, Evalue=0.0,
Organism=Escherichia coli, GI3868720, Length=807, Percent_Identity=61.3382899628253, Blast_Score=1058, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=254, Percent_Identity=33.0708661417323, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1787778, Length=258, Percent_Identity=28.2945736434109, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787870, Length=236, Percent_Identity=27.9661016949153, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI171474008, Length=226, Percent_Identity=26.9911504424779, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI87081797, Length=237, Percent_Identity=27.8481012658228, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 91426; Mature: 91295

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNWVDIKNANLIIVQGGNPAEAHPVGFRWAIEAKKNGAKIIVIDPRFNRTASVADLHA
CCCCEEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCHHHHHH
PIRSGSDITFLMGVIRYLLETNQIQHEYVKHYTNASFLIDEGFKFEDGLFVGYNEEKRNY
HHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEECCCEECCCEEEEECHHHHCC
DKSKWNYQFDENGHAKRDMTLQHPRCVINILKEHVSRYTPEMVERITGVKQKLFLQICEE
CCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IGKTSVPNKTMTHLYALGFTEHSIGTQNIRSMAIIQLLLGNMGMPGGGINALRGHSNVQG
HCCCCCCCHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCC
TTDMGLLPMSLPGYMRLPNDKDTSYDQYINAITPKDIVPNQVNYYRHTSKFFVSMMKTFY
CCCCCEEEECCCCCEECCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GDNATKENGWGFDFLPKADRLYDPITHVKLMNEGKLHGWILQGFNVLNSLPNKNKTLSGM
CCCCCCCCCCCCCCCCCCHHHHCCHHHEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHH
SKLKYLVVMDPLQTESSEFWKNFGESNDVNPAEIQTEVFRLPTTCFAEEEGSIVNSGRWT
HHCEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEECCCCCCEECCCCEE
QWHWKGCDQPGEALPDVDILSMLREEMHELYKKEGGQGIESFEAMTWNYAQPHSPSAVEL
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHEECCCCCCCCCHHHHH
AKELNGYALEDLYDPNGNLMYKKGQLLNGFAHLRDDGTTTSGNWLYVGQWTEKGNQTANR
HHHCCCEEEEHEECCCCCEEEECCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCC
DNSDPSGLGCTIGWGFAWPANRRVLYSRASLDINGNPWDKNRQLIKWNGKNWNWFDIADY
CCCCCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEECCCCCEEEECCC
GTQPPGSDTGPFIMSAEGVGRLFAVDKIANGPMPEHYEPVESPIDTNPFHPNVVTDPTLR
CCCCCCCCCCCEEEECCCCCEEEEEHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHE
IYKEDREFIGSNKEYPFVATTYRLTEHFHSWTAQSALNIIAQPQQFVEIGEKLAAEKGIQ
EEEHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
KGDMVKITSRRGYIKAVAVVTKRLKDLEIDGRVVHHIGLPIHWNMKALNGKGNRGFSTNT
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECEEEECCCCCCCCCCCC
LTPSWGEAITQTPEYKTFLVNIEKVGEA
CCCCHHHHHHCCCCCEEEEEEHHHCCCC
>Mature Secondary Structure 
TNNWVDIKNANLIIVQGGNPAEAHPVGFRWAIEAKKNGAKIIVIDPRFNRTASVADLHA
CCCEEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCHHHHHH
PIRSGSDITFLMGVIRYLLETNQIQHEYVKHYTNASFLIDEGFKFEDGLFVGYNEEKRNY
HHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEECCCEECCCEEEEECHHHHCC
DKSKWNYQFDENGHAKRDMTLQHPRCVINILKEHVSRYTPEMVERITGVKQKLFLQICEE
CCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IGKTSVPNKTMTHLYALGFTEHSIGTQNIRSMAIIQLLLGNMGMPGGGINALRGHSNVQG
HCCCCCCCHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCC
TTDMGLLPMSLPGYMRLPNDKDTSYDQYINAITPKDIVPNQVNYYRHTSKFFVSMMKTFY
CCCCCEEEECCCCCEECCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
GDNATKENGWGFDFLPKADRLYDPITHVKLMNEGKLHGWILQGFNVLNSLPNKNKTLSGM
CCCCCCCCCCCCCCCCCCHHHHCCHHHEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHH
SKLKYLVVMDPLQTESSEFWKNFGESNDVNPAEIQTEVFRLPTTCFAEEEGSIVNSGRWT
HHCEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEECCCCCCEECCCCEE
QWHWKGCDQPGEALPDVDILSMLREEMHELYKKEGGQGIESFEAMTWNYAQPHSPSAVEL
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHEECCCCCCCCCHHHHH
AKELNGYALEDLYDPNGNLMYKKGQLLNGFAHLRDDGTTTSGNWLYVGQWTEKGNQTANR
HHHCCCEEEEHEECCCCCEEEECCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCC
DNSDPSGLGCTIGWGFAWPANRRVLYSRASLDINGNPWDKNRQLIKWNGKNWNWFDIADY
CCCCCCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEECCCCCEEEECCC
GTQPPGSDTGPFIMSAEGVGRLFAVDKIANGPMPEHYEPVESPIDTNPFHPNVVTDPTLR
CCCCCCCCCCCEEEECCCCCEEEEEHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHE
IYKEDREFIGSNKEYPFVATTYRLTEHFHSWTAQSALNIIAQPQQFVEIGEKLAAEKGIQ
EEEHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
KGDMVKITSRRGYIKAVAVVTKRLKDLEIDGRVVHHIGLPIHWNMKALNGKGNRGFSTNT
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECEEEECCCCCCCCCCCC
LTPSWGEAITQTPEYKTFLVNIEKVGEA
CCCCHHHHHHCCCCCEEEEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]