Click here to switch to the map view.

The map label for this gene is fdxG

Identifier: 148827166

GI number: 148827166

Start: 458303

End: 458914

Strand: Direct

Name: fdxG

Synonym: CGSHiGG_02490

Alternate gene names: 148827166

Gene position: 458303-458914 (Clockwise)

Preceding gene: 148827162

Following gene: 148827167

Centisome position: 24.28

GC content: 42.81

Gene sequence:

>612_bases
ATGCAGGTCTCAAGAAGAAAATTCTTCAAGATCTGTGCAGGAGGTATGGCGGGAACGTCAGCTGCAATGTTGGGCTTTGC
TCCAGCAAACGTATTAGCTGCGCCACGCGAATATAAATTATTACGCGCGTTTGAATCCCGTAACACCTGTACATATTGCG
CTGTAAGTTGCGGTATGTTGTTATATAGCACAGGCAAACCTTACAATTCATTAAGCAGCCATACTGGCACAAATACTCGT
TCAAAACTCTTTCATATTGAGGGTGATCCAGATCATCCAGTCAGTCGTGGTGCGCTTTGCCCGAAAGGTGCTGGCTCACT
CGATTATGTCAATAGTGAAAGCCGTTCTTTATATCCTCAATATCGTGCGCCAGGTTCTGATAAATGGGAACGAATTTCTT
GGAAAGATGCCATTAAACGTATTGCTCGTTTAATGAAAGATGACCGAGATGCCAACTTTGTTGAAAAAGATTCAAATGGA
AAAACGGTTAATCGTTGGGCAACGACAGGAATTATGACTGCATCAGCAATGAGCAATGAAGCTGCGTTATTAACACAAAA
GTGGATTAGAATGCTCGGTATGGTGCCAGTATGTAACCAAGCGAATACTTGA

Upstream 100 bases:

>100_bases
TAGAGAGTGTTATTTTAACGAAATCAACATAATCTAGCTACTAAACGAATTTTATTACTATCTATAATATCTCAACAACT
TGTTGTTGAAAGGAGTGATT

Downstream 100 bases:

>100_bases
CACGGACCAACGGTAGCAAGTCTTGCTCCATCATTTGGTCGCGGTGCCATGACAAATAACTGGGTTGATATTAAAAATGC
CAACTTAATCATCGTTCAAG

Product: formate dehydrogenase major subunit

Products: NA

Alternate protein names: Formate dehydrogenase subunit alpha; FDH subunit alpha

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MQVSRRKFFKICAGGMAGTSAAMLGFAPANVLAAPREYKLLRAFESRNTCTYCAVSCGMLLYSTGKPYNSLSSHTGTNTR
SKLFHIEGDPDHPVSRGALCPKGAGSLDYVNSESRSLYPQYRAPGSDKWERISWKDAIKRIARLMKDDRDANFVEKDSNG
KTVNRWATTGIMTASAMSNEAALLTQKWIRMLGMVPVCNQANT

Sequences:

>Translated_203_residues
MQVSRRKFFKICAGGMAGTSAAMLGFAPANVLAAPREYKLLRAFESRNTCTYCAVSCGMLLYSTGKPYNSLSSHTGTNTR
SKLFHIEGDPDHPVSRGALCPKGAGSLDYVNSESRSLYPQYRAPGSDKWERISWKDAIKRIARLMKDDRDANFVEKDSNG
KTVNRWATTGIMTASAMSNEAALLTQKWIRMLGMVPVCNQANT
>Mature_203_residues
MQVSRRKFFKICAGGMAGTSAAMLGFAPANVLAAPREYKLLRAFESRNTCTYCAVSCGMLLYSTGKPYNSLSSHTGTNTR
SKLFHIEGDPDHPVSRGALCPKGAGSLDYVNSESRSLYPQYRAPGSDKWERISWKDAIKRIARLMKDDRDANFVEKDSNG
KTVNRWATTGIMTASAMSNEAALLTQKWIRMLGMVPVCNQANT

Specific function: Allows to use formate as major electron donor during anaerobic respiration. Subunit alpha possibly forms the active site

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family

Homologues:

Organism=Escherichia coli, GI3868719, Length=201, Percent_Identity=66.1691542288557, Blast_Score=281, Evalue=3e-77,
Organism=Escherichia coli, GI3868720, Length=201, Percent_Identity=62.6865671641791, Blast_Score=274, Evalue=4e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FDXG_HAEIN (P46448)

Other databases:

- EMBL:   L42023
- GenomeReviews:   L42023_GR
- TIGR:   HI_0006
- HOGENOM:   HBG436656
- OMA:   QNIRSMA
- BRENDA:   1.2.1.2
- GO:   GO:0005737
- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311
- Gene3D:   G3DSA:2.40.40.20
- SMART:   SM00926
- TIGRFAMs:   TIGR01553
- TIGRFAMs:   TIGR01409

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; SSF50692 Asp_decarb_fold

EC number: =1.2.1.2

Molecular weight: Translated: 22360; Mature: 22360

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1; PS00490 MOLYBDOPTERIN_PROK_2; PS00932 MOLYBDOPTERIN_PROK_3; PS51318 TAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSRRKFFKICAGGMAGTSAAMLGFAPANVLAAPREYKLLRAFESRNTCTYCAVSCGML
CCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LYSTGKPYNSLSSHTGTNTRSKLFHIEGDPDHPVSRGALCPKGAGSLDYVNSESRSLYPQ
EEECCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YRAPGSDKWERISWKDAIKRIARLMKDDRDANFVEKDSNGKTVNRWATTGIMTASAMSNE
CCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCEEHHHHHHHHHHHHHCCCH
AALLTQKWIRMLGMVPVCNQANT
HHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQVSRRKFFKICAGGMAGTSAAMLGFAPANVLAAPREYKLLRAFESRNTCTYCAVSCGML
CCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LYSTGKPYNSLSSHTGTNTRSKLFHIEGDPDHPVSRGALCPKGAGSLDYVNSESRSLYPQ
EEECCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YRAPGSDKWERISWKDAIKRIARLMKDDRDANFVEKDSNGKTVNRWATTGIMTASAMSNE
CCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCEEHHHHHHHHHHHHHCCCH
AALLTQKWIRMLGMVPVCNQANT
HHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800