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The map label for this gene is modE [H]

Identifier: 148827117

GI number: 148827117

Start: 393402

End: 394169

Strand: Direct

Name: modE [H]

Synonym: CGSHiGG_02210

Alternate gene names: 148827117

Gene position: 393402-394169 (Clockwise)

Preceding gene: 148827113

Following gene: 148827124

Centisome position: 20.85

GC content: 41.02

Gene sequence:

>768_bases
ATGAAAAACACCGAAATTTTACTCACCATTAAACTTCAACAAGCACTTTTTATCGATCCAAAACGAGTTCGTTTACTCAA
AGAAATTCAACAATGCGGTTCGATTAATCAAGCTGCGAAAAATGCAAAAGTGAGCTATAAAAGTGCGTGGGATCATTTAG
AAGCCATGAATAAAATCAGCCCTCGCCCATTGCTGGAACGAAATACAGGTGGAAAAAATGGCGGAGGCACGGCACTTACT
ACTTATGCCGAGCGTTTGCTACAGCTTTATGATTTATTAGAACGTACGCAAGAACACGCGTTTCATATTCTACAAGATGA
ATCCGTGCCGTTAGATAGTTTGCTCACGGCAACCGCACGTTTTTCTTTACAAAGTAGCGCACGCAATCAATTTTTTGGGC
GAGTGGTACAACAACGAATCATTGACTCTCGTTGTGTTGTGGATGTGAATGTGCAAGGATTACCAACGCCGTTGCAAGTT
TCTATTACCACAAAAAGCTCGGCTCGTTTGAAACTCATTACGGAAAAAGAAGTGATGCTGATGTTCAAGGCTCCTTGGGT
AAAAATCAGTGAACAACCATTAGCAAATCAACCGAATCAGTTCCCTGTAAATATCAAATCACTCAATGAAGAAGAAGCCA
TCCTTCAATTTGCTGAAAGCGACATTGAATTTTGTGCCACGGTCCACCAGCCAAATCAATGGCAAATCGGGCAACAGGTT
TGGATTCATATTGATCAAGAGCAAATTATTTTAGCAACGCTGGGGTAA

Upstream 100 bases:

>100_bases
ATATATTGAAATAAATAACAATCATATAGCAAAATAAAAATTATTTAGTAAAATATATAACGCTTAGGCTTACCACTTAG
GATTACTTAGGGACAGCAAA

Downstream 100 bases:

>100_bases
TTCAGAGATATAATACGTAAATTCAATACTTATATTTATTGTTTTCTGAACTAAAATAACCTCAAATCAAACAAAATTTT
AAATAAAATATTTAATTTCA

Product: molybdenum transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKNTEILLTIKLQQALFIDPKRVRLLKEIQQCGSINQAAKNAKVSYKSAWDHLEAMNKISPRPLLERNTGGKNGGGTALT
TYAERLLQLYDLLERTQEHAFHILQDESVPLDSLLTATARFSLQSSARNQFFGRVVQQRIIDSRCVVDVNVQGLPTPLQV
SITTKSSARLKLITEKEVMLMFKAPWVKISEQPLANQPNQFPVNIKSLNEEEAILQFAESDIEFCATVHQPNQWQIGQQV
WIHIDQEQIILATLG

Sequences:

>Translated_255_residues
MKNTEILLTIKLQQALFIDPKRVRLLKEIQQCGSINQAAKNAKVSYKSAWDHLEAMNKISPRPLLERNTGGKNGGGTALT
TYAERLLQLYDLLERTQEHAFHILQDESVPLDSLLTATARFSLQSSARNQFFGRVVQQRIIDSRCVVDVNVQGLPTPLQV
SITTKSSARLKLITEKEVMLMFKAPWVKISEQPLANQPNQFPVNIKSLNEEEAILQFAESDIEFCATVHQPNQWQIGQQV
WIHIDQEQIILATLG
>Mature_255_residues
MKNTEILLTIKLQQALFIDPKRVRLLKEIQQCGSINQAAKNAKVSYKSAWDHLEAMNKISPRPLLERNTGGKNGGGTALT
TYAERLLQLYDLLERTQEHAFHILQDESVPLDSLLTATARFSLQSSARNQFFGRVVQQRIIDSRCVVDVNVQGLPTPLQV
SITTKSSARLKLITEKEVMLMFKAPWVKISEQPLANQPNQFPVNIKSLNEEEAILQFAESDIEFCATVHQPNQWQIGQQV
WIHIDQEQIILATLG

Specific function: The modE-Mo complex acts as a repressor of the modABC operon, involved in the transport of molybdate. Upon binding molybdate, the conformation of the protein changes, promoting dimerization of ModE-Mo. The protein dimer is then competent to bind a DNA reg

COG id: COG2005

COG function: function code R; N-terminal domain of molybdenum-binding protein

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the modE family [H]

Homologues:

Organism=Escherichia coli, GI1786976, Length=246, Percent_Identity=45.5284552845528, Blast_Score=179, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR004606
- InterPro:   IPR008995
- InterPro:   IPR003725
- InterPro:   IPR016462
- InterPro:   IPR005116
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03459 TOBE [H]

EC number: NA

Molecular weight: Translated: 28856; Mature: 28856

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTEILLTIKLQQALFIDPKRVRLLKEIQQCGSINQAAKNAKVSYKSAWDHLEAMNKIS
CCCCEEEEEEEECHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCC
PRPLLERNTGGKNGGGTALTTYAERLLQLYDLLERTQEHAFHILQDESVPLDSLLTATAR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHH
FSLQSSARNQFFGRVVQQRIIDSRCVVDVNVQGLPTPLQVSITTKSSARLKLITEKEVML
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEECCEEEE
MFKAPWVKISEQPLANQPNQFPVNIKSLNEEEAILQFAESDIEFCATVHQPNQWQIGQQV
EEECCCEEECCCCCCCCCCCCCEEHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCEE
WIHIDQEQIILATLG
EEEECCCEEEEEECC
>Mature Secondary Structure
MKNTEILLTIKLQQALFIDPKRVRLLKEIQQCGSINQAAKNAKVSYKSAWDHLEAMNKIS
CCCCEEEEEEEECHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCC
PRPLLERNTGGKNGGGTALTTYAERLLQLYDLLERTQEHAFHILQDESVPLDSLLTATAR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHH
FSLQSSARNQFFGRVVQQRIIDSRCVVDVNVQGLPTPLQVSITTKSSARLKLITEKEVML
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCEEEEEECCEEEE
MFKAPWVKISEQPLANQPNQFPVNIKSLNEEEAILQFAESDIEFCATVHQPNQWQIGQQV
EEECCCEEECCCCCCCCCCCCCEEHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCEE
WIHIDQEQIILATLG
EEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 9325422 [H]