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The map label for this gene is uup-A [H]

Identifier: 148827004

GI number: 148827004

Start: 246032

End: 247975

Strand: Reverse

Name: uup-A [H]

Synonym: CGSHiGG_01460

Alternate gene names: 148827004

Gene position: 247975-246032 (Counterclockwise)

Preceding gene: 148827005

Following gene: 148827001

Centisome position: 13.14

GC content: 39.61

Gene sequence:

>1944_bases
GTGGCATTAATTAGTTTAACCAATGGATATCTTTCCTTTAGTGATGCACCTTTGTTAGATCACGCAGAACTACATATTGA
ACCGAATGAACGTGTTTGTTTAGTTGGGCGTAACGGTGCAGGTAAATCAACTTTATTGAAAATCATCGCAGGCGATGTGC
TTATGGATGATGGCAAAATCCAATACGAAAAAGATCTTGTGGTTTCTCGTTTAGAACAAGACCCACCGCGTAATGCACAA
GGCAATATTTTTGATTATGTCGCGGAAGGCGTAGGGCATTTAACGGATTTATTGAAAGAATATCATCAGATTTCTGTTCA
ATTGGAAGAAAATTACAGTGATCAAATTTTAAGTCAATTAGAGCAAGTTCAGGCTAAATTAGAACACGCTGATGGCTGGC
GATTTGAAAATAAAATCAATGAAGTATTGTTAAAACTAGGTTTAAATCCAAACACAAAATTATCCGCACTTTCGGGCGGT
TGGTTACGCAAAGCGGCACTCGCACGTGCATTGGTGTGCGATCCTGATGTGTTATTACTTGATGAACCAACTAACCACTT
GGATGTGGAAGCTATTGAATGGCTGGAAAATTTCTTACTGGATTTCCAAGGTAGCATTGTATTTATTTCCCATGACCGTT
CTTTTATTCGCAAAATGGCAACACGGATTGTGGATTTAGATCGCGGTCAATTGCAGTCTTATCTAGGCAATTACGATTTA
TATTTAACCACGAAAGAAGAAAATCTACGCGTTGAAGCCTTGCAGAATGAATTATTTGATAAACGACTTGCACAGGAAGA
AGTGTGGATTCGCCAAGGTATCAAGGCTCGCCGCACAAGAAATGAAGGGCGAGTGCGAGCATTAAAAGCGATGCGTGAGG
AACGCCGCCAACGCCGTGACGTAATGGGAACAGCCAAATTACAGTTAGATACCTCAAGTCGTTCTGGCAAAATTGTCTTT
GAAATGGAAGATGTGAGCTATGAAATCGCAGGAAAAACCTTGTTAAAAGATTTTTCAACAACGATTTTACGTGGAGATAA
AATTGCACTTGTTGGGCCAAATGGCTGTGGGAAAACCACGTTCATTAAATTATTGCTGGGTGAAATTCAGCCAACATCAG
GCAAAATTCGTTGTGGTACTAAATTAGATATTGCTTATTTTGACCAATACCGTGCTGATTTAGATCCCGAAAAAACCGTA
ATGGATAATGTGTCAGATGGCAAACAAGATATTGAAGTTAATGGTGTAAAACGCCACGTGCTAGGGTATTTGCAAGATTT
CTTGTTCCCGCCCAAACGAGCAATGACCCCAGTTAAAGCCTTATCGGGGGGAGAACGAAATCGTTTATTGCTCGCAAAAT
TGTTGCTCAAACCAAATAATTTATTGATTCTTGACGAACCGACCAATGACCTTGATGTAGAAACATTGGAGCTTTTAGAA
GAAATTTTGACTGATTATCAAGGCACATTGTTAATTGTGAGCCATGACCGTCAATTTATCGATAATACTGCCACAGAATG
TTATTTATTCGAAGGTAAAGGGCGTTTGAATAAGTATGTGGGTGGATTCTTTGATGCGAAACAGCAACAAGCCAATTTCT
GGGCAAGTAAAGCAGTGGAAGAGCAGGCTAAAGCGAAGAAATCTGAACCGCTAAAAGAAGAAAGTGCGGTGAAAAATGAC
CGCACTTCTAAGCCGAAATCCGTGAAACTTTCTTATAAAGAACAACGAGAGCTAGAACAACTTCCACAACTATTGGAAGA
GTTGGAAACTAAAATCACCGTACTTCAAGCTGAAATAGCCGATCCAGCATTTTTCCAACAGGCTCACGATATTACCGACG
CTAAATTAAAAGCATTGGCGGATACTGAAGCCGAATTAGAAACAGCATTTTTACGCTGGGAAGAATTAGAAGAAAAGAAA
AATTTGGTTGAAGGTAAAGCTTAA

Upstream 100 bases:

>100_bases
ACTTTGATTTAAGAGAGAATCCCATCGAATTGATGGGATTTTTTATGCAAACCGTATAGAATAGTGCGGTTAATTTTCAC
TGAATTTTTATGGGGCAGTT

Downstream 100 bases:

>100_bases
AAAATAACGCCCGAAAGGGCGTTTTTTTTATGTATTTTCAAGATGATCTTTTTTCAAAATATTTTCTTCATCAAGTATTG
ATAAACGAGCGATAGCGTTT

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 646

Protein sequence:

>647_residues
MALISLTNGYLSFSDAPLLDHAELHIEPNERVCLVGRNGAGKSTLLKIIAGDVLMDDGKIQYEKDLVVSRLEQDPPRNAQ
GNIFDYVAEGVGHLTDLLKEYHQISVQLEENYSDQILSQLEQVQAKLEHADGWRFENKINEVLLKLGLNPNTKLSALSGG
WLRKAALARALVCDPDVLLLDEPTNHLDVEAIEWLENFLLDFQGSIVFISHDRSFIRKMATRIVDLDRGQLQSYLGNYDL
YLTTKEENLRVEALQNELFDKRLAQEEVWIRQGIKARRTRNEGRVRALKAMREERRQRRDVMGTAKLQLDTSSRSGKIVF
EMEDVSYEIAGKTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGEIQPTSGKIRCGTKLDIAYFDQYRADLDPEKTV
MDNVSDGKQDIEVNGVKRHVLGYLQDFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
EILTDYQGTLLIVSHDRQFIDNTATECYLFEGKGRLNKYVGGFFDAKQQQANFWASKAVEEQAKAKKSEPLKEESAVKND
RTSKPKSVKLSYKEQRELEQLPQLLEELETKITVLQAEIADPAFFQQAHDITDAKLKALADTEAELETAFLRWEELEEKK
NLVEGKA

Sequences:

>Translated_647_residues
MALISLTNGYLSFSDAPLLDHAELHIEPNERVCLVGRNGAGKSTLLKIIAGDVLMDDGKIQYEKDLVVSRLEQDPPRNAQ
GNIFDYVAEGVGHLTDLLKEYHQISVQLEENYSDQILSQLEQVQAKLEHADGWRFENKINEVLLKLGLNPNTKLSALSGG
WLRKAALARALVCDPDVLLLDEPTNHLDVEAIEWLENFLLDFQGSIVFISHDRSFIRKMATRIVDLDRGQLQSYLGNYDL
YLTTKEENLRVEALQNELFDKRLAQEEVWIRQGIKARRTRNEGRVRALKAMREERRQRRDVMGTAKLQLDTSSRSGKIVF
EMEDVSYEIAGKTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGEIQPTSGKIRCGTKLDIAYFDQYRADLDPEKTV
MDNVSDGKQDIEVNGVKRHVLGYLQDFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
EILTDYQGTLLIVSHDRQFIDNTATECYLFEGKGRLNKYVGGFFDAKQQQANFWASKAVEEQAKAKKSEPLKEESAVKND
RTSKPKSVKLSYKEQRELEQLPQLLEELETKITVLQAEIADPAFFQQAHDITDAKLKALADTEAELETAFLRWEELEEKK
NLVEGKA
>Mature_646_residues
ALISLTNGYLSFSDAPLLDHAELHIEPNERVCLVGRNGAGKSTLLKIIAGDVLMDDGKIQYEKDLVVSRLEQDPPRNAQG
NIFDYVAEGVGHLTDLLKEYHQISVQLEENYSDQILSQLEQVQAKLEHADGWRFENKINEVLLKLGLNPNTKLSALSGGW
LRKAALARALVCDPDVLLLDEPTNHLDVEAIEWLENFLLDFQGSIVFISHDRSFIRKMATRIVDLDRGQLQSYLGNYDLY
LTTKEENLRVEALQNELFDKRLAQEEVWIRQGIKARRTRNEGRVRALKAMREERRQRRDVMGTAKLQLDTSSRSGKIVFE
MEDVSYEIAGKTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGEIQPTSGKIRCGTKLDIAYFDQYRADLDPEKTVM
DNVSDGKQDIEVNGVKRHVLGYLQDFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLEE
ILTDYQGTLLIVSHDRQFIDNTATECYLFEGKGRLNKYVGGFFDAKQQQANFWASKAVEEQAKAKKSEPLKEESAVKNDR
TSKPKSVKLSYKEQRELEQLPQLLEELETKITVLQAEIADPAFFQQAHDITDAKLKALADTEAELETAFLRWEELEEKKN
LVEGKA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=536, Percent_Identity=31.3432835820896, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI10947137, Length=563, Percent_Identity=29.3072824156306, Blast_Score=202, Evalue=8e-52,
Organism=Homo sapiens, GI27881506, Length=563, Percent_Identity=29.3072824156306, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI10947135, Length=553, Percent_Identity=30.5605786618445, Blast_Score=189, Evalue=7e-48,
Organism=Homo sapiens, GI69354671, Length=553, Percent_Identity=30.5605786618445, Blast_Score=189, Evalue=7e-48,
Organism=Homo sapiens, GI9955963, Length=231, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI73747915, Length=213, Percent_Identity=28.169014084507, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1787182, Length=641, Percent_Identity=65.990639625585, Blast_Score=834, Evalue=0.0,
Organism=Escherichia coli, GI2367384, Length=528, Percent_Identity=34.6590909090909, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1789751, Length=647, Percent_Identity=29.3663060278207, Blast_Score=268, Evalue=8e-73,
Organism=Escherichia coli, GI1787041, Length=509, Percent_Identity=31.8271119842829, Blast_Score=262, Evalue=6e-71,
Organism=Escherichia coli, GI1788165, Length=193, Percent_Identity=30.5699481865285, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=30.3921568627451, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787712, Length=269, Percent_Identity=26.0223048327138, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790467, Length=249, Percent_Identity=28.9156626506024, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787029, Length=244, Percent_Identity=28.2786885245902, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790190, Length=226, Percent_Identity=26.1061946902655, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786563, Length=249, Percent_Identity=26.9076305220884, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787164, Length=219, Percent_Identity=31.9634703196347, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786872, Length=204, Percent_Identity=28.921568627451, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789873, Length=239, Percent_Identity=27.1966527196653, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786975, Length=215, Percent_Identity=27.906976744186, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789962, Length=225, Percent_Identity=28, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787758, Length=176, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788225, Length=224, Percent_Identity=26.7857142857143, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081709, Length=245, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788472, Length=552, Percent_Identity=20.4710144927536, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788761, Length=198, Percent_Identity=28.2828282828283, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87081834, Length=204, Percent_Identity=27.9411764705882, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=556, Percent_Identity=28.5971223021583, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17555318, Length=540, Percent_Identity=29.8148148148148, Blast_Score=204, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI17553372, Length=551, Percent_Identity=29.94555353902, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17511077, Length=291, Percent_Identity=27.4914089347079, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=218, Percent_Identity=25.6880733944954, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=533, Percent_Identity=29.4559099437148, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6320874, Length=529, Percent_Identity=29.6786389413989, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6325030, Length=385, Percent_Identity=28.8311688311688, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6323278, Length=385, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6324314, Length=388, Percent_Identity=28.0927835051546, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24666836, Length=539, Percent_Identity=30.7977736549165, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24642252, Length=563, Percent_Identity=29.3072824156306, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI18859989, Length=563, Percent_Identity=29.3072824156306, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24641342, Length=551, Percent_Identity=29.2196007259528, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI281363262, Length=217, Percent_Identity=26.7281105990783, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24653245, Length=219, Percent_Identity=26.9406392694064, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 73346; Mature: 73214

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALISLTNGYLSFSDAPLLDHAELHIEPNERVCLVGRNGAGKSTLLKIIAGDVLMDDGKI
CEEEEEECCCEECCCCCCCCCCEEEECCCCCEEEEECCCCCHHHHHHHHHCCEEECCCCE
QYEKDLVVSRLEQDPPRNAQGNIFDYVAEGVGHLTDLLKEYHQISVQLEENYSDQILSQL
EEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHH
EQVQAKLEHADGWRFENKINEVLLKLGLNPNTKLSALSGGWLRKAALARALVCDPDVLLL
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEEE
DEPTNHLDVEAIEWLENFLLDFQGSIVFISHDRSFIRKMATRIVDLDRGQLQSYLGNYDL
ECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCEE
YLTTKEENLRVEALQNELFDKRLAQEEVWIRQGIKARRTRNEGRVRALKAMREERRQRRD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
VMGTAKLQLDTSSRSGKIVFEMEDVSYEIAGKTLLKDFSTTILRGDKIALVGPNGCGKTT
CCCEEEEEEECCCCCCEEEEEEECCCEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
FIKLLLGEIQPTSGKIRCGTKLDIAYFDQYRADLDPEKTVMDNVSDGKQDIEVNGVKRHV
HHHHHHHHCCCCCCCEEECCEEEHHHHHHHHCCCCCHHHHHCCCCCCCCCEEECHHHHHH
LGYLQDFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
HHHHHHHCCCCHHHCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
EILTDYQGTLLIVSHDRQFIDNTATECYLFEGKGRLNKYVGGFFDAKQQQANFWASKAVE
HHHHCCCCEEEEEECCHHHHCCCCCEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHH
EQAKAKKSEPLKEESAVKNDRTSKPKSVKLSYKEQRELEQLPQLLEELETKITVLQAEIA
HHHHHHCCCCCCHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHEEEHHHHC
DPAFFQQAHDITDAKLKALADTEAELETAFLRWEELEEKKNLVEGKA
CHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALISLTNGYLSFSDAPLLDHAELHIEPNERVCLVGRNGAGKSTLLKIIAGDVLMDDGKI
EEEEEECCCEECCCCCCCCCCEEEECCCCCEEEEECCCCCHHHHHHHHHCCEEECCCCE
QYEKDLVVSRLEQDPPRNAQGNIFDYVAEGVGHLTDLLKEYHQISVQLEENYSDQILSQL
EEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHH
EQVQAKLEHADGWRFENKINEVLLKLGLNPNTKLSALSGGWLRKAALARALVCDPDVLLL
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHCCCCCEEEE
DEPTNHLDVEAIEWLENFLLDFQGSIVFISHDRSFIRKMATRIVDLDRGQLQSYLGNYDL
ECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCCEE
YLTTKEENLRVEALQNELFDKRLAQEEVWIRQGIKARRTRNEGRVRALKAMREERRQRRD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
VMGTAKLQLDTSSRSGKIVFEMEDVSYEIAGKTLLKDFSTTILRGDKIALVGPNGCGKTT
CCCEEEEEEECCCCCCEEEEEEECCCEEHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
FIKLLLGEIQPTSGKIRCGTKLDIAYFDQYRADLDPEKTVMDNVSDGKQDIEVNGVKRHV
HHHHHHHHCCCCCCCEEECCEEEHHHHHHHHCCCCCHHHHHCCCCCCCCCEEECHHHHHH
LGYLQDFLFPPKRAMTPVKALSGGERNRLLLAKLLLKPNNLLILDEPTNDLDVETLELLE
HHHHHHHCCCCHHHCCHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
EILTDYQGTLLIVSHDRQFIDNTATECYLFEGKGRLNKYVGGFFDAKQQQANFWASKAVE
HHHHCCCCEEEEEECCHHHHCCCCCEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHH
EQAKAKKSEPLKEESAVKNDRTSKPKSVKLSYKEQRELEQLPQLLEELETKITVLQAEIA
HHHHHHCCCCCCHHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHEEEHHHHC
DPAFFQQAHDITDAKLKALADTEAELETAFLRWEELEEKKNLVEGKA
CHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]