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The map label for this gene is thiL [H]

Identifier: 148826999

GI number: 148826999

Start: 241645

End: 242631

Strand: Reverse

Name: thiL [H]

Synonym: CGSHiGG_01435

Alternate gene names: 148826999

Gene position: 242631-241645 (Counterclockwise)

Preceding gene: 148827000

Following gene: 148826998

Centisome position: 12.86

GC content: 37.99

Gene sequence:

>987_bases
ATGGCAATGGGTGAATTTGATTTAATTAAACGATATTTTCAGCAACAAATATTAGTTGATGATTCCGTTCAATTATCTAT
TGGCGACGATTGTGCGCTGGTTTCCGTGCCAGAGAATTATCAGCTTGCCATTACGACCGATACAATGGTGGAAAATACGC
ATTTTTTACCAACCATTTCACCTGAGGACTTGGCTTATAAGGCGGTTGCAACAAATTTAAGTGATCTTGCTGCAATGGGG
GCACAGCCAAAATGGGTTTCACTGGCATTAACTTTGCCAAATGTAGACGAAAATTGGATTTCAACATTTAGCCAAAGTTT
ATTACACACGTTAAAACAATACAACGTCACATTAATTGGTGGCGATACTACAAAAGGTAATTTGTCTATTACGATTACGG
CACAAGGTTTTGTCGAAAAAAACAAAGGAATTTGTCGGCATAAAGCACAAATCGGTGATTTAATTTATGTTTCAAGCACT
TTAGGCGATAGCGCGGCAGGTTTAACACAAATTTTATTGGGCAAAAGTGCGGTTGATTCTGATGATGTTTTTTTGCAACA
ACGACATCTTAGACCCACACCTAGAATTGAACTTGGGCAGGCGTTAATTGGCATTGCTCATGTTGCCATTGATCTTTCCG
ATGGGCTAATATCTGATTTAGGGCATATTCTTGAACGAAGTCAATGTAGTGCTGAAGTTGAACTGACTGCATTACCTCTT
TCATCATCGATTTTAAATAAATATGATCGCACTCAAGCGGAACAATTTGCCTTAAGTGGTGGCGAAGATTATGAACTCTG
TTTTACTATACCGCCCAAATCTAAAGATGAATTAGAATTACGCTTGAAAAAACTGAACGTGCCTTGTACTTGCATTGGTA
AAATCACTGAAAAGTGCGGTGACTTTTCTCCCCGTTTTTTACGGGATGGAAAACCTGTGAATATAACTTTTTCAAGTGGT
TTCGATCATTTTAAGGAATCAAAATGA

Upstream 100 bases:

>100_bases
GATAAAATCGCACCAGCATTAGGGCGTAAATAATCCTTTTAAACTGAGAATGGCGCGCGTTTTTAATGCGTGCCTTTTCT
TTTATAAGATAGGTGGAAAA

Downstream 100 bases:

>100_bases
CAGAAAATAATCCTCTTAAAAAAATCTCTCTTTTAAATCCTATTCATTTGCTTGCCGTTGGTTTTGGCTCGGGTTTAATT
TATCCAGCACCCGGCACTTG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MAMGEFDLIKRYFQQQILVDDSVQLSIGDDCALVSVPENYQLAITTDTMVENTHFLPTISPEDLAYKAVATNLSDLAAMG
AQPKWVSLALTLPNVDENWISTFSQSLLHTLKQYNVTLIGGDTTKGNLSITITAQGFVEKNKGICRHKAQIGDLIYVSST
LGDSAAGLTQILLGKSAVDSDDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSDGLISDLGHILERSQCSAEVELTALPL
SSSILNKYDRTQAEQFALSGGEDYELCFTIPPKSKDELELRLKKLNVPCTCIGKITEKCGDFSPRFLRDGKPVNITFSSG
FDHFKESK

Sequences:

>Translated_328_residues
MAMGEFDLIKRYFQQQILVDDSVQLSIGDDCALVSVPENYQLAITTDTMVENTHFLPTISPEDLAYKAVATNLSDLAAMG
AQPKWVSLALTLPNVDENWISTFSQSLLHTLKQYNVTLIGGDTTKGNLSITITAQGFVEKNKGICRHKAQIGDLIYVSST
LGDSAAGLTQILLGKSAVDSDDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSDGLISDLGHILERSQCSAEVELTALPL
SSSILNKYDRTQAEQFALSGGEDYELCFTIPPKSKDELELRLKKLNVPCTCIGKITEKCGDFSPRFLRDGKPVNITFSSG
FDHFKESK
>Mature_327_residues
AMGEFDLIKRYFQQQILVDDSVQLSIGDDCALVSVPENYQLAITTDTMVENTHFLPTISPEDLAYKAVATNLSDLAAMGA
QPKWVSLALTLPNVDENWISTFSQSLLHTLKQYNVTLIGGDTTKGNLSITITAQGFVEKNKGICRHKAQIGDLIYVSSTL
GDSAAGLTQILLGKSAVDSDDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSDGLISDLGHILERSQCSAEVELTALPLS
SSILNKYDRTQAEQFALSGGEDYELCFTIPPKSKDELELRLKKLNVPCTCIGKITEKCGDFSPRFLRDGKPVNITFSSGF
DHFKESK

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=325, Percent_Identity=52.9230769230769, Blast_Score=335, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35926; Mature: 35795

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMGEFDLIKRYFQQQILVDDSVQLSIGDDCALVSVPENYQLAITTDTMVENTHFLPTIS
CCCCHHHHHHHHHHHHEEECCCEEEEECCCEEEEECCCCCEEEEEECCEECCCCCCCCCC
PEDLAYKAVATNLSDLAAMGAQPKWVSLALTLPNVDENWISTFSQSLLHTLKQYNVTLIG
HHHHHHHHHHCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEE
GDTTKGNLSITITAQGFVEKNKGICRHKAQIGDLIYVSSTLGDSAAGLTQILLGKSAVDS
CCCCCCEEEEEEEECCCEECCCCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCCCCCC
DDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSDGLISDLGHILERSQCSAEVELTALPL
CHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECC
SSSILNKYDRTQAEQFALSGGEDYELCFTIPPKSKDELELRLKKLNVPCTCIGKITEKCG
CHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEHHHHHHHHC
DFSPRFLRDGKPVNITFSSGFDHFKESK
CCCCHHHCCCCCEEEEECCCCCHHHCCC
>Mature Secondary Structure 
AMGEFDLIKRYFQQQILVDDSVQLSIGDDCALVSVPENYQLAITTDTMVENTHFLPTIS
CCCHHHHHHHHHHHHEEECCCEEEEECCCEEEEECCCCCEEEEEECCEECCCCCCCCCC
PEDLAYKAVATNLSDLAAMGAQPKWVSLALTLPNVDENWISTFSQSLLHTLKQYNVTLIG
HHHHHHHHHHCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEE
GDTTKGNLSITITAQGFVEKNKGICRHKAQIGDLIYVSSTLGDSAAGLTQILLGKSAVDS
CCCCCCEEEEEEEECCCEECCCCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCCCCCC
DDVFLQQRHLRPTPRIELGQALIGIAHVAIDLSDGLISDLGHILERSQCSAEVELTALPL
CHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECC
SSSILNKYDRTQAEQFALSGGEDYELCFTIPPKSKDELELRLKKLNVPCTCIGKITEKCG
CHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEHHHHHHHHC
DFSPRFLRDGKPVNITFSSGFDHFKESK
CCCCHHHCCCCCEEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]