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The map label for this gene is moeB [H]

Identifier: 148826952

GI number: 148826952

Start: 193960

End: 194691

Strand: Direct

Name: moeB [H]

Synonym: CGSHiGG_01130

Alternate gene names: 148826952

Gene position: 193960-194691 (Clockwise)

Preceding gene: 148826951

Following gene: 148826953

Centisome position: 10.28

GC content: 40.16

Gene sequence:

>732_bases
ATGATCGAACTTAGTCACGAAGAAGAATTGCGTTATAACCGTCAAATTATTCTTAAAAGCGTAGATTTTGACGGGCAAGA
AAAACTTAAAGCAAGCAAAATGCTGATCGTTGGGCTTGGTGGCTTAGGATGTGCAGCCAGCCAATATCTCGCAGCAGCAG
GTGTTGGAAATTTAACGCTGTTGGATTTCGACACAGTTTCTCTTTCGAATCTTCAACGACAAGTCTTGCACTGCGATGCT
CGTTTGAATATGCCCAAAGTGGAGTCAGCTAAAATTGCACTCAAGCAAATCAATCCACATATAAACATAGAGACGATTAA
TGCGAAGTTAGACGAAGAAAAACTGGCTGAAATCATTCCGCACTTTGATATTGTTTTAGATTGTACAGACAATGTGGAAA
TCCGTAATCAATTGGATCGCCAATGTAATCATGCAAAAATTCCTCTTATTTCTGGTGCCGCAATTCGGATGGAAGGTCAG
GTTTCCGTTTTCACTTATGAACCAAATACGCCCACTTATCGTGATCTCAGCAAATTATTTGGACAAAATGTATTAAGCTG
TGTGGAGGCTGGCGTGCTTGCACCAATCGTCGGCATTGTGGGCACGATTCAAGCCTTAGAAGCAATTAAAGTGCGGTTAA
AAATCGGTAAGAATTTGTGTGGCCGCTTATTGATGATTGATGGTTTTTCGATGAATATTCGAGAAATTAAACTTCCAACC
AATATGGAATAA

Upstream 100 bases:

>100_bases
AAAAAGCAATTGTTTTATCGTGTTAGAACAAGAACGTGGCAATGTCTCTGCGGGCGAAACAGTGACAATTGAGCCTTTCA
ATCATTTATTAGGATAAAAA

Downstream 100 bases:

>100_bases
AACCCTTAAAAAGAGAAAAAATTTAACCGCACTTTTTATTAACCATAACCTTTACGACAAAACACTATGACAACAGAAAT
TAAAAAACTTGATCCCGATA

Product: molybdopterin biosynthesis protein MoeB

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MIELSHEEELRYNRQIILKSVDFDGQEKLKASKMLIVGLGGLGCAASQYLAAAGVGNLTLLDFDTVSLSNLQRQVLHCDA
RLNMPKVESAKIALKQINPHINIETINAKLDEEKLAEIIPHFDIVLDCTDNVEIRNQLDRQCNHAKIPLISGAAIRMEGQ
VSVFTYEPNTPTYRDLSKLFGQNVLSCVEAGVLAPIVGIVGTIQALEAIKVRLKIGKNLCGRLLMIDGFSMNIREIKLPT
NME

Sequences:

>Translated_243_residues
MIELSHEEELRYNRQIILKSVDFDGQEKLKASKMLIVGLGGLGCAASQYLAAAGVGNLTLLDFDTVSLSNLQRQVLHCDA
RLNMPKVESAKIALKQINPHINIETINAKLDEEKLAEIIPHFDIVLDCTDNVEIRNQLDRQCNHAKIPLISGAAIRMEGQ
VSVFTYEPNTPTYRDLSKLFGQNVLSCVEAGVLAPIVGIVGTIQALEAIKVRLKIGKNLCGRLLMIDGFSMNIREIKLPT
NME
>Mature_243_residues
MIELSHEEELRYNRQIILKSVDFDGQEKLKASKMLIVGLGGLGCAASQYLAAAGVGNLTLLDFDTVSLSNLQRQVLHCDA
RLNMPKVESAKIALKQINPHINIETINAKLDEEKLAEIIPHFDIVLDCTDNVEIRNQLDRQCNHAKIPLISGAAIRMEGQ
VSVFTYEPNTPTYRDLSKLFGQNVLSCVEAGVLAPIVGIVGTIQALEAIKVRLKIGKNLCGRLLMIDGFSMNIREIKLPT
NME

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=228, Percent_Identity=39.4736842105263, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI23510338, Length=162, Percent_Identity=30.8641975308642, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI23510340, Length=162, Percent_Identity=30.8641975308642, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI4885649, Length=138, Percent_Identity=31.1594202898551, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI38045948, Length=163, Percent_Identity=30.0613496932515, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787048, Length=241, Percent_Identity=64.3153526970954, Blast_Score=325, Evalue=1e-90,
Organism=Escherichia coli, GI87082356, Length=235, Percent_Identity=40.8510638297872, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI1789177, Length=139, Percent_Identity=28.7769784172662, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540406, Length=237, Percent_Identity=39.2405063291139, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI193203301, Length=139, Percent_Identity=35.9712230215827, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321903, Length=241, Percent_Identity=38.1742738589212, Blast_Score=157, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6322639, Length=165, Percent_Identity=31.5151515151515, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582879, Length=238, Percent_Identity=46.6386554621849, Blast_Score=207, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24660640, Length=139, Percent_Identity=33.0935251798561, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28573937, Length=161, Percent_Identity=31.6770186335404, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26849; Mature: 26849

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELSHEEELRYNRQIILKSVDFDGQEKLKASKMLIVGLGGLGCAASQYLAAAGVGNLTL
CCCCCCHHHHHHCCEEEEEECCCCCHHHHHHCEEEEEECCCCCHHHHHHHHHCCCCCEEE
LDFDTVSLSNLQRQVLHCDARLNMPKVESAKIALKQINPHINIETINAKLDEEKLAEIIP
EEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCC
HFDIVLDCTDNVEIRNQLDRQCNHAKIPLISGAAIRMEGQVSVFTYEPNTPTYRDLSKLF
CCEEEEECCCCCHHHHHHHHCCCCCCCEEECCCEEEEECEEEEEEECCCCCCHHHHHHHH
GQNVLSCVEAGVLAPIVGIVGTIQALEAIKVRLKIGKNLCGRLLMIDGFSMNIREIKLPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEEEEECCCCCEEEEECCC
NME
CCC
>Mature Secondary Structure
MIELSHEEELRYNRQIILKSVDFDGQEKLKASKMLIVGLGGLGCAASQYLAAAGVGNLTL
CCCCCCHHHHHHCCEEEEEECCCCCHHHHHHCEEEEEECCCCCHHHHHHHHHCCCCCEEE
LDFDTVSLSNLQRQVLHCDARLNMPKVESAKIALKQINPHINIETINAKLDEEKLAEIIP
EEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCC
HFDIVLDCTDNVEIRNQLDRQCNHAKIPLISGAAIRMEGQVSVFTYEPNTPTYRDLSKLF
CCEEEEECCCCCHHHHHHHHCCCCCCCEEECCCEEEEECEEEEEEECCCCCCHHHHHHHH
GQNVLSCVEAGVLAPIVGIVGTIQALEAIKVRLKIGKNLCGRLLMIDGFSMNIREIKLPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCEEEEEECCCCCEEEEECCC
NME
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]