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The map label for this gene is mdaB [H]

Identifier: 148826718

GI number: 148826718

Start: 1769359

End: 1769937

Strand: Direct

Name: mdaB [H]

Synonym: CGSHiEE_08965

Alternate gene names: 148826718

Gene position: 1769359-1769937 (Clockwise)

Preceding gene: 148826716

Following gene: 148826719

Centisome position: 97.59

GC content: 42.66

Gene sequence:

>579_bases
ATGAATATTTTATTATTAGACGGCGGTAAGGCGTTTGGTCATTCTCACGGCGAGTTGAACCATTCGCTTCACAAAAAAGC
GAAAGAAGTTTTGACCGCACTTGGACACAATGTCAAAGAAACTGTAATTGATGCTGGTTATGACGTTGAAGCTGAAATCG
AAAAATTCTTGTGGATGGATACCGTGATTTGGCAAATGCCGAGCTGGTGGATGCATGAGCCTTGGACAGTGAAAAAATAC
ATAGACGAAGTATTAACCAGTGGGTACGGCAAGTTATATCACAGTGATGGCAGACACAGCGTTAATCCAACCGAGGGCTA
TGGCACAGGCGGCTTGTTGCAAGGCAAAAAACACATGCTTTCACTGACTTGGAATGCACCGATTGAAGCCTTTACCCGCG
AAAGCTATTTCTTTGAAGGCAAAGGCGTAGATGTTTTGTATATGCATTTCCACAAACTCAACGAGTTCATCGGTTTGACT
CGCCTGCCGACATTCTTATGTAACGATGTGGTTAAAAATCCGCAAGTAGAACAATACTTAGTCGATTACCAAGCACACTT
GGAAAAAGTGTTTGGTTAA

Upstream 100 bases:

>100_bases
TTAGCGCAAAAGTAGTTTTTTTATTTTTGCACTTTTAAAGTATAAAGTAAAACAGCACAATGAAATCCCTTTTTTAATTA
TTTATTTTAGGAGCAAAAAG

Downstream 100 bases:

>100_bases
TAAAAAAATCCATCTTCAATACGAAGATGGATTTTTTGTTTATTTCGTTAAGATTCGTTCAGAATCTACCAAGTTTTTTG
GGCAGCCAAGGCTTACAAAG

Product: putative NADPH-quinone reductase, modulator of drug activity B

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNILLLDGGKAFGHSHGELNHSLHKKAKEVLTALGHNVKETVIDAGYDVEAEIEKFLWMDTVIWQMPSWWMHEPWTVKKY
IDEVLTSGYGKLYHSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTRESYFFEGKGVDVLYMHFHKLNEFIGLT
RLPTFLCNDVVKNPQVEQYLVDYQAHLEKVFG

Sequences:

>Translated_192_residues
MNILLLDGGKAFGHSHGELNHSLHKKAKEVLTALGHNVKETVIDAGYDVEAEIEKFLWMDTVIWQMPSWWMHEPWTVKKY
IDEVLTSGYGKLYHSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTRESYFFEGKGVDVLYMHFHKLNEFIGLT
RLPTFLCNDVVKNPQVEQYLVDYQAHLEKVFG
>Mature_192_residues
MNILLLDGGKAFGHSHGELNHSLHKKAKEVLTALGHNVKETVIDAGYDVEAEIEKFLWMDTVIWQMPSWWMHEPWTVKKY
IDEVLTSGYGKLYHSDGRHSVNPTEGYGTGGLLQGKKHMLSLTWNAPIEAFTRESYFFEGKGVDVLYMHFHKLNEFIGLT
RLPTFLCNDVVKNPQVEQYLVDYQAHLEKVFG

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli madB and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=191, Percent_Identity=56.5445026178011, Blast_Score=240, Evalue=6e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 22024; Mature: 22024

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILLLDGGKAFGHSHGELNHSLHKKAKEVLTALGHNVKETVIDAGYDVEAEIEKFLWMD
CEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHH
TVIWQMPSWWMHEPWTVKKYIDEVLTSGYGKLYHSDGRHSVNPTEGYGTGGLLQGKKHML
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEE
SLTWNAPIEAFTRESYFFEGKGVDVLYMHFHKLNEFIGLTRLPTFLCNDVVKNPQVEQYL
EEEECCCHHHHHCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VDYQAHLEKVFG
HHHHHHHHHHCC
>Mature Secondary Structure
MNILLLDGGKAFGHSHGELNHSLHKKAKEVLTALGHNVKETVIDAGYDVEAEIEKFLWMD
CEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHH
TVIWQMPSWWMHEPWTVKKYIDEVLTSGYGKLYHSDGRHSVNPTEGYGTGGLLQGKKHML
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEE
SLTWNAPIEAFTRESYFFEGKGVDVLYMHFHKLNEFIGLTRLPTFLCNDVVKNPQVEQYL
EEEECCCHHHHHCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VDYQAHLEKVFG
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]