| Definition | Haemophilus influenzae PittEE chromosome, complete genome. |
|---|---|
| Accession | NC_009566 |
| Length | 1,813,033 |
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The map label for this gene is uvrD [H]
Identifier: 148826204
GI number: 148826204
Start: 1211775
End: 1213955
Strand: Direct
Name: uvrD [H]
Synonym: CGSHiEE_06105
Alternate gene names: 148826204
Gene position: 1211775-1213955 (Clockwise)
Preceding gene: 148826203
Following gene: 148826205
Centisome position: 66.84
GC content: 40.03
Gene sequence:
>2181_bases ATGGATATTTCTGAATTACTTGACGGACTCAACGATAAACAACGCGAAGCCGTAGCTGCTCCTCTTGGTAATCACTTAGT GCTAGCTGGTGCAGGCTCGGGCAAAACGCGTGTATTGACGCACCGTATTGCTTGGTTAATTGCGGTCGAAAATATTTCTG AAGGCAGCATTATGGCGGTGACCTTTACCAATAAAGCCGCAGCAGAAATGCGTCATCGTATTCAATCTACCCTTGCCAAA CACGCACAACATCAATTATTTGGTATGTGGATTGGCACCTTCCATAGCATTGCTCATCGTTTGTTGCGAGCTCATCATTT AGATGTGGGATTGCCACAAGATTTCCAAATTTTAGATTCAGAAGATCAACGTCGTTTAATTAAACGATTATTAAAATTAC ATAATTTTGATGAAAAAGCTTTTCCGCCTAAACAGGCTTGTTGGTACATCAATAACAAAAAAGATGAAGGCTTGCGACCA AATGATATTGAAGATTTTAATGATCGCCAAGAACGTGAATGGATTAAAATTTATCAGATCTATCAAGACACTTGCGATCG CGCAGGGTTGGTCGATTTTGCTGAATTATTAATTCGGGTCTATGAATTATTTGAGAAAAAACCATTAATTTTGCAACGTT ATCAACAACGTTTTCAGCATATTTTGGTGGATGAGTTTCAAGACACCAATAAAATTCAATATAAGTGGATTAAAATTCTT GCTGGAAAAACAGGCAAAGTCATGATCGTAGGCGATGATGATCAATCTATATACGGTTGGCGTGGCGCACAAATTGAAAA TATCCAAAAATTCTTGAAAGATTTCAAAGCCGAAACAATTCGCCTTGAACAAAACTACCGTTCTACCGCCAATATCCTAA ACAGCGCAAATGAATTAATTGCAAACAATAGTGATCGTCTTGGTAAAAATTTATGGACAGAGGGTGAGAAAGGCGATCCT GTGGGCATCTATTCTGCCTTTAATGAATTAGATGAAGCAAAATTTGTCGCTTCACAAATTCAGGATTGGGTAGAACATGG CGGAAAACTTGATGATTGCGCTGTACTTTATCGTAGTAATAGCCAATCACGGGTTATTGAAGAAGCTTTAATTCGTTGTC AAATTCCATACCGTATTTATGGCGGTATGCGTTTCTTCGAACGTCAAGAAATTAAAGATGCGTTAGCCTATCTTCGTTTG ATTAATAATCGTCAAGATGATGCGGCTTTTGAGCGTGTAATTAATACGCCAACCCGTGGCATTGGCGACCGCACTTTAGA TATATTGCGTAACTTAACACGCGAACGCCAAATTACCTTATGGCAAGCAGTACAAGTCGCAACACAAGAAAATATGTTGG CAGGGCGAGCCTCAACAGCCTTATTACGTTTCCAAGAATTAATTAATTCACTACAACTTGATACCGCAGAAATGCCGCTT TTCGCACAAACTGATTTTGTGATTAAACATTCGGGCTTATATGAAATGTATCAACAAGAAAAAGGCGAAAAAGGCGAAGT GCGGATTGAAAATTTGGAAGAATTAGTTACCGCAACCCGTGAATTTATCAAACCTGATGATGCGGAAGAAATGACCGAAC TCACTGCCTTTTTAACTCATGCCTCTTTAGAAGCTGGTGAAGAACAAGCCTCGCCGCATCAATCTTGTGTAGAAATGATG ACGTTGCACTCTGCGAAAGGCTTAGAATTTCCTCGTGTATTTATGGTGGGCGTAGAAGAAGGATTATTCCCAAGTTTTCG TTCTTTTGAAGAACCCGGACGTTTAGAAGAAGAGCGTCGTTTAGCTTATGTCGGTATTACTCGCGCACAGAAAAAACTGA CCATCTCTTATGCGGAAAGCCGTCGATTATATGCCAAAGAAGAACGCCATTTGCCATCACGGTTTATCGCAGAATTACCG AGAGAATGTATCCAAGAAATTCGTTTACGAGGGACAGTCACGCGTGCGATGAACCTAGCAAAAGTCGGTTCATTGTCGAA TACCAGTGCGGTCGAAAATGAATGGAAAATGGGTCAAAAAGTTAAACACGAAAAATTTGGTTTCGGCACAGTGATTAATG TGGAAGGATCTGAAAATAACACACGTTTACAAATAGCGTTCCAAGCTCAAGGCATTAAATGGTTGATTGCGCATTTGGCA ACATTGGAAAAAGTGCGGTAG
Upstream 100 bases:
>100_bases TGTTCTACCCTACTTTTGATATACTCACAAATCTTATTGTTTCACAAGATAGATGGGACTATAATAACTGTAAATTTAAA CAGATTAAAGATAGTTTATG
Downstream 100 bases:
>100_bases AATTCAAGAGTATTATATTTTTTACCGATTAATTTCTTTGAAAAGTGCGGTGAATTTTTACCGCACTTTTATTATCTACG AGTGATGGAATGTTTAAATT
Product: DNA-dependent helicase II
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 726; Mature: 726
Protein sequence:
>726_residues MDISELLDGLNDKQREAVAAPLGNHLVLAGAGSGKTRVLTHRIAWLIAVENISEGSIMAVTFTNKAAAEMRHRIQSTLAK HAQHQLFGMWIGTFHSIAHRLLRAHHLDVGLPQDFQILDSEDQRRLIKRLLKLHNFDEKAFPPKQACWYINNKKDEGLRP NDIEDFNDRQEREWIKIYQIYQDTCDRAGLVDFAELLIRVYELFEKKPLILQRYQQRFQHILVDEFQDTNKIQYKWIKIL AGKTGKVMIVGDDDQSIYGWRGAQIENIQKFLKDFKAETIRLEQNYRSTANILNSANELIANNSDRLGKNLWTEGEKGDP VGIYSAFNELDEAKFVASQIQDWVEHGGKLDDCAVLYRSNSQSRVIEEALIRCQIPYRIYGGMRFFERQEIKDALAYLRL INNRQDDAAFERVINTPTRGIGDRTLDILRNLTRERQITLWQAVQVATQENMLAGRASTALLRFQELINSLQLDTAEMPL FAQTDFVIKHSGLYEMYQQEKGEKGEVRIENLEELVTATREFIKPDDAEEMTELTAFLTHASLEAGEEQASPHQSCVEMM TLHSAKGLEFPRVFMVGVEEGLFPSFRSFEEPGRLEEERRLAYVGITRAQKKLTISYAESRRLYAKEERHLPSRFIAELP RECIQEIRLRGTVTRAMNLAKVGSLSNTSAVENEWKMGQKVKHEKFGFGTVINVEGSENNTRLQIAFQAQGIKWLIAHLA TLEKVR
Sequences:
>Translated_726_residues MDISELLDGLNDKQREAVAAPLGNHLVLAGAGSGKTRVLTHRIAWLIAVENISEGSIMAVTFTNKAAAEMRHRIQSTLAK HAQHQLFGMWIGTFHSIAHRLLRAHHLDVGLPQDFQILDSEDQRRLIKRLLKLHNFDEKAFPPKQACWYINNKKDEGLRP NDIEDFNDRQEREWIKIYQIYQDTCDRAGLVDFAELLIRVYELFEKKPLILQRYQQRFQHILVDEFQDTNKIQYKWIKIL AGKTGKVMIVGDDDQSIYGWRGAQIENIQKFLKDFKAETIRLEQNYRSTANILNSANELIANNSDRLGKNLWTEGEKGDP VGIYSAFNELDEAKFVASQIQDWVEHGGKLDDCAVLYRSNSQSRVIEEALIRCQIPYRIYGGMRFFERQEIKDALAYLRL INNRQDDAAFERVINTPTRGIGDRTLDILRNLTRERQITLWQAVQVATQENMLAGRASTALLRFQELINSLQLDTAEMPL FAQTDFVIKHSGLYEMYQQEKGEKGEVRIENLEELVTATREFIKPDDAEEMTELTAFLTHASLEAGEEQASPHQSCVEMM TLHSAKGLEFPRVFMVGVEEGLFPSFRSFEEPGRLEEERRLAYVGITRAQKKLTISYAESRRLYAKEERHLPSRFIAELP RECIQEIRLRGTVTRAMNLAKVGSLSNTSAVENEWKMGQKVKHEKFGFGTVINVEGSENNTRLQIAFQAQGIKWLIAHLA TLEKVR >Mature_726_residues MDISELLDGLNDKQREAVAAPLGNHLVLAGAGSGKTRVLTHRIAWLIAVENISEGSIMAVTFTNKAAAEMRHRIQSTLAK HAQHQLFGMWIGTFHSIAHRLLRAHHLDVGLPQDFQILDSEDQRRLIKRLLKLHNFDEKAFPPKQACWYINNKKDEGLRP NDIEDFNDRQEREWIKIYQIYQDTCDRAGLVDFAELLIRVYELFEKKPLILQRYQQRFQHILVDEFQDTNKIQYKWIKIL AGKTGKVMIVGDDDQSIYGWRGAQIENIQKFLKDFKAETIRLEQNYRSTANILNSANELIANNSDRLGKNLWTEGEKGDP VGIYSAFNELDEAKFVASQIQDWVEHGGKLDDCAVLYRSNSQSRVIEEALIRCQIPYRIYGGMRFFERQEIKDALAYLRL INNRQDDAAFERVINTPTRGIGDRTLDILRNLTRERQITLWQAVQVATQENMLAGRASTALLRFQELINSLQLDTAEMPL FAQTDFVIKHSGLYEMYQQEKGEKGEVRIENLEELVTATREFIKPDDAEEMTELTAFLTHASLEAGEEQASPHQSCVEMM TLHSAKGLEFPRVFMVGVEEGLFPSFRSFEEPGRLEEERRLAYVGITRAQKKLTISYAESRRLYAKEERHLPSRFIAELP RECIQEIRLRGTVTRAMNLAKVGSLSNTSAVENEWKMGQKVKHEKFGFGTVINVEGSENNTRLQIAFQAQGIKWLIAHLA TLEKVR
Specific function: May process damage occurring in non-replicating regions of DNA to produce recombinational intermediates for sister strand recombinational exchange [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI2367296, Length=728, Percent_Identity=67.3076923076923, Blast_Score=1021, Evalue=0.0, Organism=Escherichia coli, GI48994965, Length=643, Percent_Identity=39.3468118195956, Blast_Score=399, Evalue=1e-112, Organism=Escherichia coli, GI1789183, Length=518, Percent_Identity=23.7451737451737, Blast_Score=79, Evalue=1e-15, Organism=Saccharomyces cerevisiae, GI6322369, Length=731, Percent_Identity=28.3173734610123, Blast_Score=186, Evalue=9e-48, Organism=Saccharomyces cerevisiae, GI6324477, Length=653, Percent_Identity=22.052067381317, Blast_Score=110, Evalue=1e-24,
Paralogues:
None
Copy number: 3000 [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005753 - InterPro: IPR013986 - InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 83514; Mature: 83514
Theoretical pI: Translated: 6.65; Mature: 6.65
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDISELLDGLNDKQREAVAAPLGNHLVLAGAGSGKTRVLTHRIAWLIAVENISEGSIMAV CCHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHEECCCCCCCEEEE TFTNKAAAEMRHRIQSTLAKHAQHQLFGMWIGTFHSIAHRLLRAHHLDVGLPQDFQILDS EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC EDQRRLIKRLLKLHNFDEKAFPPKQACWYINNKKDEGLRPNDIEDFNDRQEREWIKIYQI HHHHHHHHHHHHHCCCCCCCCCCCHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH YQDTCDRAGLVDFAELLIRVYELFEKKPLILQRYQQRFQHILVDEFQDTNKIQYKWIKIL HHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEE AGKTGKVMIVGDDDQSIYGWRGAQIENIQKFLKDFKAETIRLEQNYRSTANILNSANELI ECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHH ANNSDRLGKNLWTEGEKGDPVGIYSAFNELDEAKFVASQIQDWVEHGGKLDDCAVLYRSN CCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEECC SQSRVIEEALIRCQIPYRIYGGMRFFERQEIKDALAYLRLINNRQDDAAFERVINTPTRG CHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC IGDRTLDILRNLTRERQITLWQAVQVATQENMLAGRASTALLRFQELINSLQLDTAEMPL CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE FAQTDFVIKHSGLYEMYQQEKGEKGEVRIENLEELVTATREFIKPDDAEEMTELTAFLTH EECCCEEEECCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH ASLEAGEEQASPHQSCVEMMTLHSAKGLEFPRVFMVGVEEGLFPSFRSFEEPGRLEEERR HHHHCCHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHCCCCCCCCCHHHC LAYVGITRAQKKLTISYAESRRLYAKEERHLPSRFIAELPRECIQEIRLRGTVTRAMNLA EEEEEEHHHHHEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KVGSLSNTSAVENEWKMGQKVKHEKFGFGTVINVEGSENNTRLQIAFQAQGIKWLIAHLA HHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCHHHHHHHHH TLEKVR HHHHCC >Mature Secondary Structure MDISELLDGLNDKQREAVAAPLGNHLVLAGAGSGKTRVLTHRIAWLIAVENISEGSIMAV CCHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHEECCCCCCCEEEE TFTNKAAAEMRHRIQSTLAKHAQHQLFGMWIGTFHSIAHRLLRAHHLDVGLPQDFQILDS EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC EDQRRLIKRLLKLHNFDEKAFPPKQACWYINNKKDEGLRPNDIEDFNDRQEREWIKIYQI HHHHHHHHHHHHHCCCCCCCCCCCHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH YQDTCDRAGLVDFAELLIRVYELFEKKPLILQRYQQRFQHILVDEFQDTNKIQYKWIKIL HHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEE AGKTGKVMIVGDDDQSIYGWRGAQIENIQKFLKDFKAETIRLEQNYRSTANILNSANELI ECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHH ANNSDRLGKNLWTEGEKGDPVGIYSAFNELDEAKFVASQIQDWVEHGGKLDDCAVLYRSN CCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEECC SQSRVIEEALIRCQIPYRIYGGMRFFERQEIKDALAYLRLINNRQDDAAFERVINTPTRG CHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC IGDRTLDILRNLTRERQITLWQAVQVATQENMLAGRASTALLRFQELINSLQLDTAEMPL CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE FAQTDFVIKHSGLYEMYQQEKGEKGEVRIENLEELVTATREFIKPDDAEEMTELTAFLTH EECCCEEEECCCHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH ASLEAGEEQASPHQSCVEMMTLHSAKGLEFPRVFMVGVEEGLFPSFRSFEEPGRLEEERR HHHHCCHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHCCCCCCCCCHHHC LAYVGITRAQKKLTISYAESRRLYAKEERHLPSRFIAELPRECIQEIRLRGTVTRAMNLA EEEEEEHHHHHEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KVGSLSNTSAVENEWKMGQKVKHEKFGFGTVINVEGSENNTRLQIAFQAQGIKWLIAHLA HHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCHHHHHHHHH TLEKVR HHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8294031; 7542800; 3259573 [H]