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The map label for this gene is purE [H]

Identifier: 148826141

GI number: 148826141

Start: 1147185

End: 1147679

Strand: Direct

Name: purE [H]

Synonym: CGSHiEE_05740

Alternate gene names: 148826141

Gene position: 1147185-1147679 (Clockwise)

Preceding gene: 148826137

Following gene: 148826142

Centisome position: 63.27

GC content: 44.24

Gene sequence:

>495_bases
ATGTCAAAAACTGCACAAATTGCTGTTGTGATGGGTTCCAAAAGCGATTGGGCTACCATGCAAGAGGCAACTCAGATTTT
AGATGAATTAAAAGTACCTTATCATGTGGAAATCGTCTCTGCTCATCGTACGCCTGATAAACTTTTTGAATTTGCTGAAA
ATGCAACAAAAAATGGCTATAAAGTAATTATTGCTGGGGCTGGCGGTGCGGCACATTTACCCGGCATGATCGCAGCCAAA
ACCCTTGTGCCTGTGCTGGGTGTGCCAGTAAAAAGTTCTATGTTAAGTGGCGTAGATAGCCTTTATTCAATTGTGCAAAT
GCCAAAAGGAATCCCAGTCGGAACATTGGCTATTGGCCCTGCGGGTGCGGCAAATGCTGGATTGTTAGCCGCACAAATTC
TAGCAAGTTGGGATGCAGAATTGCTTTCACGCTTGCAATCTTTCCGTGAAAGCCAAACGAGTAATGTGCTTGATAATCCC
GATCCACGCACATAA

Upstream 100 bases:

>100_bases
AATCCCCATTAATACTTACATAAATAGCAAACGTTTGCTCAATATATGTAATCTATGCTATTCTACGCCACCTTTTTAAT
TAGAAAATTGAGAAAATAGC

Downstream 100 bases:

>100_bases
AAATATCTTCAGATCTGACCGCACTTTTAAAGTGCGGTTGTTTTTTTCGTAAATTTAACGAGAAATATTATGCAAAACTC
CACCTTATACCCAACGGTTT

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSKTAQIAVVMGSKSDWATMQEATQILDELKVPYHVEIVSAHRTPDKLFEFAENATKNGYKVIIAGAGGAAHLPGMIAAK
TLVPVLGVPVKSSMLSGVDSLYSIVQMPKGIPVGTLAIGPAGAANAGLLAAQILASWDAELLSRLQSFRESQTSNVLDNP
DPRT

Sequences:

>Translated_164_residues
MSKTAQIAVVMGSKSDWATMQEATQILDELKVPYHVEIVSAHRTPDKLFEFAENATKNGYKVIIAGAGGAAHLPGMIAAK
TLVPVLGVPVKSSMLSGVDSLYSIVQMPKGIPVGTLAIGPAGAANAGLLAAQILASWDAELLSRLQSFRESQTSNVLDNP
DPRT
>Mature_163_residues
SKTAQIAVVMGSKSDWATMQEATQILDELKVPYHVEIVSAHRTPDKLFEFAENATKNGYKVIIAGAGGAAHLPGMIAAKT
LVPVLGVPVKSSMLSGVDSLYSIVQMPKGIPVGTLAIGPAGAANAGLLAAQILASWDAELLSRLQSFRESQTSNVLDNPD
PRT

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=159, Percent_Identity=77.3584905660377, Blast_Score=218, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6324702, Length=151, Percent_Identity=51.6556291390728, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 17211; Mature: 17080

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTAQIAVVMGSKSDWATMQEATQILDELKVPYHVEIVSAHRTPDKLFEFAENATKNGY
CCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCC
KVIIAGAGGAAHLPGMIAAKTLVPVLGVPVKSSMLSGVDSLYSIVQMPKGIPVGTLAIGP
EEEEECCCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
AGAANAGLLAAQILASWDAELLSRLQSFRESQTSNVLDNPDPRT
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SKTAQIAVVMGSKSDWATMQEATQILDELKVPYHVEIVSAHRTPDKLFEFAENATKNGY
CCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCC
KVIIAGAGGAAHLPGMIAAKTLVPVLGVPVKSSMLSGVDSLYSIVQMPKGIPVGTLAIGP
EEEEECCCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
AGAANAGLLAAQILASWDAELLSRLQSFRESQTSNVLDNPDPRT
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 7997179 [H]