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The map label for this gene is alr [H]

Identifier: 148826096

GI number: 148826096

Start: 1092572

End: 1093654

Strand: Direct

Name: alr [H]

Synonym: CGSHiEE_05465

Alternate gene names: 148826096

Gene position: 1092572-1093654 (Clockwise)

Preceding gene: 148826095

Following gene: 148826097

Centisome position: 60.26

GC content: 40.54

Gene sequence:

>1083_bases
ATGAACGTAAAACCGGCGACAGCGAAAATCAGTTCGCACGCCTTAAAACAAAATTTAGAAATAATTAAACAAAAAGCACC
AAATAGCAAAATTATTGCTGTGGTTAAAGCAAACGCTTATGGTCACGGCGTTGTGTTTGTTGCATCAACTTTAGAACAAA
ATGTCGATTGCTTTGGCGTGGCTCGTTTAGAAGAGGCTTTAGCATTACGCTCCAACGGCATCACTAAACCGATTTTATTA
CTTGAAGGCTTTTTTAATGAACAAGATTTGCCTATTCTAGCCGTTAATAATATTGAAACCGTGGTACACAATCACGAACA
GCTTGAGGCTTTAAAACGTTCAAATTTACCAAGTCCAATTAAGGTTTGGTTAAAAATAGATACGGGAATGCACCGTTTAG
GCGTTGCTCTTGATGAAGTGGATTATTTTTATCAAGAACTGAAAAAACTCCCTCAAATTCAACCGCACTTAGGCTTTGTC
AGCCATTTCAGCCGAGCCGATGAACTAGAATCAGATTACACCCAACTTCAAATCAATCGTTTTTTATCCGCCACAAAAGA
TAAACAAGGTGAACGCACTATCGCAGCTTCTGGCGGCATTCTTTTCTGGCCAAAATCTCACTTAGAATGTATTCGCCCAG
GCATTATTATGTACGGCATTTCTCCAACTGATACTATTGGCAAAGAGTTTGGCTTAACGCCAGTGATGAATTTAACCTCG
TCATTAATTGCCGTTCGCCATCATAAACAAGGCGATCCTGTAGGTTACGGCGGTATTTGGACAAGTCCACGAGATACCAA
AATTGGCGTGGTCGCAATGGGTTATGGCGATGGTTATCCGCGCGATGTGCCAGAAGGTACGCCTGTTTATTTAAATGGCC
GTCTCGTACCAATTGTTGGACGTGTGTCAATGGATATGCTCACTGTTGATTTAGGCGCAGATAGCCAAGATTTGGTAGGC
GATGAAGTAATTTTATGGGGCAAGGAATTACCTATTGAAACCGTAGCTAAATTCACAGGCATTTTAAGCTACGAGCTAAT
TACAAAATTAACACCTCGTGTTATAACTGAATACGTTGATTAA

Upstream 100 bases:

>100_bases
CCCAATTGGTCGAGTGCGGTTAAAATTTAATGGACAATTCTCACGCTTTGACAATCTTGCCGAACAACGTGAATATCGAG
ATGATTATTAAGGAAAAATA

Downstream 100 bases:

>100_bases
TCACTGCATTTTTTGAACAGAGGGAGTCATTCTCCCTAATAAAAATTCCAGAAAGTGCGGTTAAAATTTCAATTATTTTT
AATGAAAGGAAATACCATGA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MNVKPATAKISSHALKQNLEIIKQKAPNSKIIAVVKANAYGHGVVFVASTLEQNVDCFGVARLEEALALRSNGITKPILL
LEGFFNEQDLPILAVNNIETVVHNHEQLEALKRSNLPSPIKVWLKIDTGMHRLGVALDEVDYFYQELKKLPQIQPHLGFV
SHFSRADELESDYTQLQINRFLSATKDKQGERTIAASGGILFWPKSHLECIRPGIIMYGISPTDTIGKEFGLTPVMNLTS
SLIAVRHHKQGDPVGYGGIWTSPRDTKIGVVAMGYGDGYPRDVPEGTPVYLNGRLVPIVGRVSMDMLTVDLGADSQDLVG
DEVILWGKELPIETVAKFTGILSYELITKLTPRVITEYVD

Sequences:

>Translated_360_residues
MNVKPATAKISSHALKQNLEIIKQKAPNSKIIAVVKANAYGHGVVFVASTLEQNVDCFGVARLEEALALRSNGITKPILL
LEGFFNEQDLPILAVNNIETVVHNHEQLEALKRSNLPSPIKVWLKIDTGMHRLGVALDEVDYFYQELKKLPQIQPHLGFV
SHFSRADELESDYTQLQINRFLSATKDKQGERTIAASGGILFWPKSHLECIRPGIIMYGISPTDTIGKEFGLTPVMNLTS
SLIAVRHHKQGDPVGYGGIWTSPRDTKIGVVAMGYGDGYPRDVPEGTPVYLNGRLVPIVGRVSMDMLTVDLGADSQDLVG
DEVILWGKELPIETVAKFTGILSYELITKLTPRVITEYVD
>Mature_360_residues
MNVKPATAKISSHALKQNLEIIKQKAPNSKIIAVVKANAYGHGVVFVASTLEQNVDCFGVARLEEALALRSNGITKPILL
LEGFFNEQDLPILAVNNIETVVHNHEQLEALKRSNLPSPIKVWLKIDTGMHRLGVALDEVDYFYQELKKLPQIQPHLGFV
SHFSRADELESDYTQLQINRFLSATKDKQGERTIAASGGILFWPKSHLECIRPGIIMYGISPTDTIGKEFGLTPVMNLTS
SLIAVRHHKQGDPVGYGGIWTSPRDTKIGVVAMGYGDGYPRDVPEGTPVYLNGRLVPIVGRVSMDMLTVDLGADSQDLVG
DEVILWGKELPIETVAKFTGILSYELITKLTPRVITEYVD

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=360, Percent_Identity=56.6666666666667, Blast_Score=430, Evalue=1e-122,
Organism=Escherichia coli, GI1787439, Length=353, Percent_Identity=41.643059490085, Blast_Score=273, Evalue=9e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39707; Mature: 39707

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKPATAKISSHALKQNLEIIKQKAPNSKIIAVVKANAYGHGVVFVASTLEQNVDCFGV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEEHHHCCCCEEEH
ARLEEALALRSNGITKPILLLEGFFNEQDLPILAVNNIETVVHNHEQLEALKRSNLPSPI
HHHHHHHHHHHCCCCCHHHEEECCCCCCCCCEEEECCHHHHHHCHHHHHHHHHCCCCCCE
KVWLKIDTGMHRLGVALDEVDYFYQELKKLPQIQPHLGFVSHFSRADELESDYTQLQINR
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FLSATKDKQGERTIAASGGILFWPKSHLECIRPGIIMYGISPTDTIGKEFGLTPVMNLTS
HHHHHCCCCCCEEEEECCCEEECCHHHHHHHCCCEEEEECCCCHHHHHHCCCCHHHHHHH
SLIAVRHHKQGDPVGYGGIWTSPRDTKIGVVAMGYGDGYPRDVPEGTPVYLNGRLVPIVG
HHHHHHHCCCCCCCCCCCEECCCCCCEEEEEEEECCCCCCCCCCCCCCEEECCEEEEEEC
RVSMDMLTVDLGADSQDLVGDEVILWGKELPIETVAKFTGILSYELITKLTPRVITEYVD
CCEEEEEEEECCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MNVKPATAKISSHALKQNLEIIKQKAPNSKIIAVVKANAYGHGVVFVASTLEQNVDCFGV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEEHHHCCCCEEEH
ARLEEALALRSNGITKPILLLEGFFNEQDLPILAVNNIETVVHNHEQLEALKRSNLPSPI
HHHHHHHHHHHCCCCCHHHEEECCCCCCCCCEEEECCHHHHHHCHHHHHHHHHCCCCCCE
KVWLKIDTGMHRLGVALDEVDYFYQELKKLPQIQPHLGFVSHFSRADELESDYTQLQINR
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FLSATKDKQGERTIAASGGILFWPKSHLECIRPGIIMYGISPTDTIGKEFGLTPVMNLTS
HHHHHCCCCCCEEEEECCCEEECCHHHHHHHCCCEEEEECCCCHHHHHHCCCCHHHHHHH
SLIAVRHHKQGDPVGYGGIWTSPRDTKIGVVAMGYGDGYPRDVPEGTPVYLNGRLVPIVG
HHHHHHHCCCCCCCCCCCEECCCCCCEEEEEEEECCCCCCCCCCCCCCEEECCEEEEEEC
RVSMDMLTVDLGADSQDLVGDEVILWGKELPIETVAKFTGILSYELITKLTPRVITEYVD
CCEEEEEEEECCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]