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The map label for this gene is moaC [H]

Identifier: 148825786

GI number: 148825786

Start: 755855

End: 756337

Strand: Direct

Name: moaC [H]

Synonym: CGSHiEE_03685

Alternate gene names: 148825786

Gene position: 755855-756337 (Clockwise)

Preceding gene: 148825785

Following gene: 148825787

Centisome position: 41.69

GC content: 42.65

Gene sequence:

>483_bases
ATGACTACATTTACACATATCAATTCTCAAGGCGAAGCCAATATGGTGGATGTTTCTGCAAAAGCAGAGACTGTTCGCGA
AGCTCGTGCTGAAGCTATCGTTACCATGTCTAAAGAAACCCTTGCTATGATCGTGGAAGGTAAACATCACAAAGGCGATG
TTTTTGCTACGGCTCGTATTGCGGGTATTCAAGCAGCAAAACGCACTTGGGAACTTATCCCGCTTTGCCATCCGTTGTTA
CTTTCTAAAGTAGAAGTGAATTTGGAACCGTTACTTGAAACAAATCGAGTTCGTATTCAATCCCTTTGCAAATTAACTGG
AAAAACTGGCGTGGAAATGGAAGCTCTAACCGCTGTAAGCGTTGCCGCTTTAACCATTTACGATATGTGTAAAGCTGTGC
AGAAAGACATTGTGATTGAGCAAGTTCGCCTGTTAGAAAAGAGCGGTGGAAAATCTGGCCATTTTGTGGCGGAGGAAAAA
TAA

Upstream 100 bases:

>100_bases
CGGTGGCTAAAAGCAAAGTGAGATGAATGGTAATATTCATCTGCTTTCTTTTGTCGCTTATTTAAAACATTTAATATTTT
AACCGCACTTTTATCATATT

Downstream 100 bases:

>100_bases
GATGTTAAATGTATTATTTTTTGCTCAAACTCGTGAATTAATTGGCGTTGATGCCATTCAATTAGAAGATGATTTTGCGA
CAGCAGACGCGGTGCGTGAA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTTFTHINSQGEANMVDVSAKAETVREARAEAIVTMSKETLAMIVEGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLL
LSKVEVNLEPLLETNRVRIQSLCKLTGKTGVEMEALTAVSVAALTIYDMCKAVQKDIVIEQVRLLEKSGGKSGHFVAEEK

Sequences:

>Translated_160_residues
MTTFTHINSQGEANMVDVSAKAETVREARAEAIVTMSKETLAMIVEGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLL
LSKVEVNLEPLLETNRVRIQSLCKLTGKTGVEMEALTAVSVAALTIYDMCKAVQKDIVIEQVRLLEKSGGKSGHFVAEEK
>Mature_159_residues
TTFTHINSQGEANMVDVSAKAETVREARAEAIVTMSKETLAMIVEGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLLL
SKVEVNLEPLLETNRVRIQSLCKLTGKTGVEMEALTAVSVAALTIYDMCKAVQKDIVIEQVRLLEKSGGKSGHFVAEEK

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=81.0126582278481, Blast_Score=264, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI32566331, Length=156, Percent_Identity=40.3846153846154, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574490, Length=158, Percent_Identity=55.0632911392405, Blast_Score=159, Evalue=6e-40,
Organism=Drosophila melanogaster, GI28574492, Length=145, Percent_Identity=56.551724137931, Blast_Score=148, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17485; Mature: 17353

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFTHINSQGEANMVDVSAKAETVREARAEAIVTMSKETLAMIVEGKHHKGDVFATARI
CCCEECCCCCCCCCEEECHHHHHHHHHHHHHHHEEECHHHEEEEECCCCCCCCEEEHHHH
AGIQAAKRTWELIPLCHPLLLSKVEVNLEPLLETNRVRIQSLCKLTGKTGVEMEALTAVS
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDIVIEQVRLLEKSGGKSGHFVAEEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC
>Mature Secondary Structure 
TTFTHINSQGEANMVDVSAKAETVREARAEAIVTMSKETLAMIVEGKHHKGDVFATARI
CCEECCCCCCCCCEEECHHHHHHHHHHHHHHHEEECHHHEEEEECCCCCCCCEEEHHHH
AGIQAAKRTWELIPLCHPLLLSKVEVNLEPLLETNRVRIQSLCKLTGKTGVEMEALTAVS
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDIVIEQVRLLEKSGGKSGHFVAEEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA