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The map label for this gene is glpG [H]

Identifier: 148825513

GI number: 148825513

Start: 404221

End: 404799

Strand: Direct

Name: glpG [H]

Synonym: CGSHiEE_02070

Alternate gene names: 148825513

Gene position: 404221-404799 (Clockwise)

Preceding gene: 148825512

Following gene: 148825514

Centisome position: 22.3

GC content: 36.27

Gene sequence:

>579_bases
ATGAAAAAATTTTTAGCTCAACAAGGAAAAATCACGTTAATTCTTACCGCACTTTGTGCGCTTATTTATCTTGCTCAACA
GCTGGGGTTTGAAGACGATATTATGTATTTGATGCATTATCCCGCTTACGAAGAGCAAGATAGCGAAGTGTGGCGTTATA
TTTCACATACATTGGTACATTTATCTAATTTGCATATTTTGTTTAATCTGTCTTGGTTTTTTATTTTCGGTGGAATGATT
GAACGCACTTTTGGTTCGGTCAAATTATTGATGTTGTATGTTGTAGCATCTGCCATAACAGGCTATGTGCAAAATTATGT
GTCTGGCCCCGCTTTTTTTGGGCTTTCTGGTGTTGTATATGCGGTTCTAGGTTATGTATTTATACGTGATAAATTGAATC
ATCATTTATTTGATCTGCCAGAAGGTTTTTTCACCATGTTATTGGTGGGGATCGCATTAGGTTTTATTAGCCCCTTATTT
GGTGTTGAAATGGGAAATGCTGCGCATATTTCAGGCTTGATTGTTGGCTTGATTTGGGGATTTATTGATAGCAAATTGTG
CAAAAATTCGCTAGAGTAA

Upstream 100 bases:

>100_bases
ACGCAGAAGAATTGACGATTACCCACCCCATTACAGGGGAAACAATGACTTTTAATGCGAAGTCCGATTTTTAAATTTAC
GCATAAGCACGAGATCACGA

Downstream 100 bases:

>100_bases
GCCTGTTTTATTTGGATAAAGGATTCGCTATGAAACAATCGTTACGCCATCAAAAAATTATTAAACTGGTGGGACAATCT
GGCTATTTAAGCACGGAAGA

Product: glp protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MKKFLAQQGKITLILTALCALIYLAQQLGFEDDIMYLMHYPAYEEQDSEVWRYISHTLVHLSNLHILFNLSWFFIFGGMI
ERTFGSVKLLMLYVVASAITGYVQNYVSGPAFFGLSGVVYAVLGYVFIRDKLNHHLFDLPEGFFTMLLVGIALGFISPLF
GVEMGNAAHISGLIVGLIWGFIDSKLCKNSLE

Sequences:

>Translated_192_residues
MKKFLAQQGKITLILTALCALIYLAQQLGFEDDIMYLMHYPAYEEQDSEVWRYISHTLVHLSNLHILFNLSWFFIFGGMI
ERTFGSVKLLMLYVVASAITGYVQNYVSGPAFFGLSGVVYAVLGYVFIRDKLNHHLFDLPEGFFTMLLVGIALGFISPLF
GVEMGNAAHISGLIVGLIWGFIDSKLCKNSLE
>Mature_192_residues
MKKFLAQQGKITLILTALCALIYLAQQLGFEDDIMYLMHYPAYEEQDSEVWRYISHTLVHLSNLHILFNLSWFFIFGGMI
ERTFGSVKLLMLYVVASAITGYVQNYVSGPAFFGLSGVVYAVLGYVFIRDKLNHHLFDLPEGFFTMLLVGIALGFISPLF
GVEMGNAAHISGLIVGLIWGFIDSKLCKNSLE

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=179, Percent_Identity=39.1061452513966, Blast_Score=136, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 21591; Mature: 21591

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFLAQQGKITLILTALCALIYLAQQLGFEDDIMYLMHYPAYEEQDSEVWRYISHTLVH
CCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LSNLHILFNLSWFFIFGGMIERTFGSVKLLMLYVVASAITGYVQNYVSGPAFFGLSGVVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AVLGYVFIRDKLNHHLFDLPEGFFTMLLVGIALGFISPLFGVEMGNAAHISGLIVGLIWG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FIDSKLCKNSLE
HHHHHHHHCCCC
>Mature Secondary Structure
MKKFLAQQGKITLILTALCALIYLAQQLGFEDDIMYLMHYPAYEEQDSEVWRYISHTLVH
CCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LSNLHILFNLSWFFIFGGMIERTFGSVKLLMLYVVASAITGYVQNYVSGPAFFGLSGVVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AVLGYVFIRDKLNHHLFDLPEGFFTMLLVGIALGFISPLFGVEMGNAAHISGLIVGLIWG
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FIDSKLCKNSLE
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]