Click here to switch to the map view.

The map label for this gene is glpR [H]

Identifier: 148825514

GI number: 148825514

Start: 404829

End: 405596

Strand: Direct

Name: glpR [H]

Synonym: CGSHiEE_02075

Alternate gene names: 148825514

Gene position: 404829-405596 (Clockwise)

Preceding gene: 148825513

Following gene: 148825518

Centisome position: 22.33

GC content: 39.97

Gene sequence:

>768_bases
ATGAAACAATCGTTACGCCATCAAAAAATTATTAAACTGGTGGGACAATCTGGCTATTTAAGCACGGAAGAATTGGTTGC
AGCCTTAGATGTTAGCCCTCAAACGATTCGTCGTGATTTGAATATTTTGGCGGAGTTAGATTTAATTCGCCGCCATCACG
GTGGTGCGGCATCGCCATCTTCTGCAGAAAATTCTGATTACGTGGATCGTAAACAATTCTTTTCATTACAAAAAAATAAT
ATTGCAAAGGAAGTTGCGAAGTTGATTCCTAACGGTGCATCGTTGTTTATTGATATTGGTACCACGCCTGAGGCTGTCGC
CAATGCGTTGCTTGGTCATGAAAAACTCAGAATTGTGACGAACAATCTGAATGCCGCTCATCTTTTACGCCAAAATGAAA
GTTTTGATATTGTCATGGCGGGCGGATCATTACGAATGGATGGTGGAATTATTGGCGAAGCTACGGTGAATTTTATTTCT
CAATTTCGCCTAGATTTCGGTATTTTAGGGATTAGTGCGATCGATGCAGATGGTTCATTATTGGATTACGATTACCATGA
AGTACAAGTCAAGCGAGCGATTATTGAAAGTTCACGTCAGACCTTATTAGTGACCGATCACTCTAAATTTTCGCGCCAAG
CGATTGTTCGCTTGGGCGAATTAAGTGATGTAGAATATTTGTTTACGGATGATGTTCCCGAAGGAATTGTTAATTATCTG
AAAGCTCAGAAAACGAAATTGGTTTTATGTAATGGTAAAGTGCGGTAA

Upstream 100 bases:

>100_bases
TTTCAGGCTTGATTGTTGGCTTGATTTGGGGATTTATTGATAGCAAATTGTGCAAAAATTCGCTAGAGTAAGCCTGTTTT
ATTTGGATAAAGGATTCGCT

Downstream 100 bases:

>100_bases
AAATATCTTTGATTTTCTTATTAATTTGTCGATAAAAGAAGCTATTACTCTTAATTTTTGATTTAATTGAACTTTATCTA
AAAGTAATCTAAATATTCTC

Product: glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKQSLRHQKIIKLVGQSGYLSTEELVAALDVSPQTIRRDLNILAELDLIRRHHGGAASPSSAENSDYVDRKQFFSLQKNN
IAKEVAKLIPNGASLFIDIGTTPEAVANALLGHEKLRIVTNNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFIS
QFRLDFGILGISAIDADGSLLDYDYHEVQVKRAIIESSRQTLLVTDHSKFSRQAIVRLGELSDVEYLFTDDVPEGIVNYL
KAQKTKLVLCNGKVR

Sequences:

>Translated_255_residues
MKQSLRHQKIIKLVGQSGYLSTEELVAALDVSPQTIRRDLNILAELDLIRRHHGGAASPSSAENSDYVDRKQFFSLQKNN
IAKEVAKLIPNGASLFIDIGTTPEAVANALLGHEKLRIVTNNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFIS
QFRLDFGILGISAIDADGSLLDYDYHEVQVKRAIIESSRQTLLVTDHSKFSRQAIVRLGELSDVEYLFTDDVPEGIVNYL
KAQKTKLVLCNGKVR
>Mature_255_residues
MKQSLRHQKIIKLVGQSGYLSTEELVAALDVSPQTIRRDLNILAELDLIRRHHGGAASPSSAENSDYVDRKQFFSLQKNN
IAKEVAKLIPNGASLFIDIGTTPEAVANALLGHEKLRIVTNNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFIS
QFRLDFGILGISAIDADGSLLDYDYHEVQVKRAIIESSRQTLLVTDHSKFSRQAIVRLGELSDVEYLFTDDVPEGIVNYL
KAQKTKLVLCNGKVR

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=62.3015873015873, Blast_Score=308, Evalue=2e-85,
Organism=Escherichia coli, GI87082344, Length=229, Percent_Identity=42.7947598253275, Blast_Score=203, Evalue=8e-54,
Organism=Escherichia coli, GI226510968, Length=247, Percent_Identity=31.5789473684211, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788069, Length=231, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=26.984126984127, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=29.4871794871795, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789059, Length=235, Percent_Identity=28.5106382978723, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787540, Length=229, Percent_Identity=28.82096069869, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787063, Length=247, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790753, Length=249, Percent_Identity=24.4979919678715, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790635, Length=154, Percent_Identity=27.9220779220779, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28128; Mature: 28128

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQSLRHQKIIKLVGQSGYLSTEELVAALDVSPQTIRRDLNILAELDLIRRHHGGAASPS
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SAENSDYVDRKQFFSLQKNNIAKEVAKLIPNGASLFIDIGTTPEAVANALLGHEKLRIVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEE
NNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFISQFRLDFGILGISAIDADGSL
CCCCHHHHHHCCCCEEEEEECCCEEECCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCCE
LDYDYHEVQVKRAIIESSRQTLLVTDHSKFSRQAIVRLGELSDVEYLFTDDVPEGIVNYL
EECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
KAQKTKLVLCNGKVR
HHCCCEEEEECCCCC
>Mature Secondary Structure
MKQSLRHQKIIKLVGQSGYLSTEELVAALDVSPQTIRRDLNILAELDLIRRHHGGAASPS
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SAENSDYVDRKQFFSLQKNNIAKEVAKLIPNGASLFIDIGTTPEAVANALLGHEKLRIVT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEE
NNLNAAHLLRQNESFDIVMAGGSLRMDGGIIGEATVNFISQFRLDFGILGISAIDADGSL
CCCCHHHHHHCCCCEEEEEECCCEEECCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCCE
LDYDYHEVQVKRAIIESSRQTLLVTDHSKFSRQAIVRLGELSDVEYLFTDDVPEGIVNYL
EECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHH
KAQKTKLVLCNGKVR
HHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]