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The map label for this gene is 148824613

Identifier: 148824613

GI number: 148824613

Start: 3835994

End: 3836560

Strand: Reverse

Name: 148824613

Synonym: TBFG_13440

Alternate gene names: NA

Gene position: 3836560-3835994 (Counterclockwise)

Preceding gene: 148824616

Following gene: 148824612

Centisome position: 86.71

GC content: 65.96

Gene sequence:

>567_bases
ATGACTACGCGTCCGGCAACCGACCGCCGCAAGATGCCCACTGGGCGGGAAGAGGTAGCGGCCGCAATCCTGCAGGCCGC
CACCGACCTGTTCGCCGAGCGTGGGCCAGCCGCGACGTCGATTCGCGACATCGCCGCTCGATCCAAGGTCAACCACGGGC
TGGTGTTTCGTCACTTCGGCACCAAGGACCAACTGGTTGGGGCCGTGCTCGATCACCTGGGCACGAAGCTGACCAGACTG
TTGCACTCCGAGGCGCCCGCTGACATCATCGAACGGGCTCTCGACCGACATGGGCGGGTCTTAGCCCGGGCACTGCTGGA
CGGATATCCCGTGGGCCAGCTGCAACAGCGATTTCCCAATGTTGCGGAGCTGCTCGACGCGGTACGGCCTCGCTACGACA
GCGACTTGGGCGCGCGGCTGGCGGTCGCGCACGCCCTTGCGCTGCAATTCGGTTGGCGGCTCTTTGCGCCCATGCTGCGC
TCGGCGACGGGTATCGACGAGCTGACCGGTGACGAACTACGGCTGTCCGTGAACGATGCGGTAGCCCGGATCCTGGAACC
GCACTGA

Upstream 100 bases:

>100_bases
ACGGCTGCCCAGCTTCTTCACGGTAATCAGATCTGTCATTGCTGGCGTCCTCAATGAATGGTTAGTGTAGTCAGATGACT
ACATCGGTTACTGTAGCCGG

Downstream 100 bases:

>100_bases
CTGATGTCCCTGCGCTGGCCCCAGCGTGGCCGTCCGGTATGCGTCGGCCCTGAAGTAGGGTGAGCTGGTGTTGGGGGCTC
CGCTGATGGGCGCTGGGCAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRL
LHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLR
SATGIDELTGDELRLSVNDAVARILEPH

Sequences:

>Translated_188_residues
MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRL
LHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLR
SATGIDELTGDELRLSVNDAVARILEPH
>Mature_187_residues
TTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLL
HSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRS
ATGIDELTGDELRLSVNDAVARILEPH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3405_MYCTU (P67442)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   B70736
- RefSeq:   NP_217922.1
- RefSeq:   NP_338037.1
- ProteinModelPortal:   P67442
- SMR:   P67442
- EnsemblBacteria:   EBMYCT00000002179
- EnsemblBacteria:   EBMYCT00000070278
- GeneID:   887940
- GeneID:   922924
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3513
- KEGG:   mtu:Rv3405c
- TIGR:   MT3513
- TubercuList:   Rv3405c
- GeneTree:   EBGT00050000014684
- HOGENOM:   HBG565716
- OMA:   WKVIARA
- ProtClustDB:   CLSK792473
- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647
- Gene3D:   G3DSA:1.10.357.10
- PRINTS:   PR00455

Pfam domain/function: PF00440 TetR_N; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 20609; Mature: 20478

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS01081 HTH_TETR_1; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECC
TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC
VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHEEHHHHH
VARILEPH
HHHHHCCC
>Mature Secondary Structure 
TTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECC
TKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPN
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC
VAELLDAVRPRYDSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHEEHHHHH
VARILEPH
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036