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The map label for this gene is sdhB [H]

Identifier: 148824523

GI number: 148824523

Start: 3718429

End: 3719220

Strand: Direct

Name: sdhB [H]

Synonym: TBFG_13350

Alternate gene names: 148824523

Gene position: 3718429-3719220 (Clockwise)

Preceding gene: 148824522

Following gene: 148824532

Centisome position: 84.04

GC content: 66.29

Gene sequence:

>792_bases
ATGAGCGTCGAGCCGGACGTCGAAACTTTGGATCCGCCCCTACCGCCGGTACCGGACGGCGCGGTGATGGTGACCGTCAA
GATCGCCCGGTTCAACCCCGACGACCCCGACGCGTTCGCGGCCACCGGCGGCTGGCAGAGCTTCCGGGTGCCCTGTTTGC
CCAGCGATCGGCTGCTCAACCTGCTCATCTACATCAAGGGCTACCTCGACGGCACGCTCACCTTCCGGCGATCCTGCGCC
CATGGGGTGTGCGGCTCTGATGCCATGCGCATCAACGGGGTGAACCGGCTGGCCTGCAAGGTGCTGATGCGTGACCTGCT
GCCGAAGAAGAAGGGCAAATCGTTGACCGTCACGGTCGAGCCGATCCGCGGGCTGCCGGTGGAAAAGGACCTGGTGGTCG
ACATGGAGCCGTTCTTCGACGCCTACCGGGCGATCAAACCGTACCTGATCACCAGCGGCAACCCGCCCACCCGCGAACGG
ATCCAGAGCCCGACCGACCGCGCCCGCTACGACGACACCACCAAGTGCATCCTGTGCGCGTGCTGCACCACCAGCTGCCC
GGTGTTCTGGCACGAGGGCAGCTACTTCGGCCCGGCGGCGATCGTCAACGCGCACCGCTTCATCTTCGACAGCCGCGACG
AGGCCGCCGCCGAGCGCCTCGACATCCTCAACGAGGTCGACGGGGTGTGGCGCTGCCGCACCACGTTCAACTGCACCGAA
TCCTGCCCACGGGGCATTGAGGTGACCAAGGCGATCCAGGAGGTCAAGCGCGCGCTGATGTTCACCCGCTGA

Upstream 100 bases:

>100_bases
TTGGGGCCGATAAGGAGGGCCCCGAGCTGCGCAGCGATGTCCGCCTTGATTTCAAACCCGTCGTGCAGACCCGTTACGAA
CCCAAGGAACGGAAGTACTA

Downstream 100 bases:

>100_bases
GGGCTTGCGCGAGCAGACGCAAAATCGCCCGAAAACCAGTGGTTTTGGGCGATTTTGCGTCTGCTCGCGCAGCCGGGTCT
ACAGCGTTGCCAGGTGCTGT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSVEPDVETLDPPLPPVPDGAVMVTVKIARFNPDDPDAFAATGGWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCA
HGVCGSDAMRINGVNRLACKVLMRDLLPKKKGKSLTVTVEPIRGLPVEKDLVVDMEPFFDAYRAIKPYLITSGNPPTRER
IQSPTDRARYDDTTKCILCACCTTSCPVFWHEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCTE
SCPRGIEVTKAIQEVKRALMFTR

Sequences:

>Translated_263_residues
MSVEPDVETLDPPLPPVPDGAVMVTVKIARFNPDDPDAFAATGGWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCA
HGVCGSDAMRINGVNRLACKVLMRDLLPKKKGKSLTVTVEPIRGLPVEKDLVVDMEPFFDAYRAIKPYLITSGNPPTRER
IQSPTDRARYDDTTKCILCACCTTSCPVFWHEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCTE
SCPRGIEVTKAIQEVKRALMFTR
>Mature_262_residues
SVEPDVETLDPPLPPVPDGAVMVTVKIARFNPDDPDAFAATGGWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCAH
GVCGSDAMRINGVNRLACKVLMRDLLPKKKGKSLTVTVEPIRGLPVEKDLVVDMEPFFDAYRAIKPYLITSGNPPTRERI
QSPTDRARYDDTTKCILCACCTTSCPVFWHEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCTES
CPRGIEVTKAIQEVKRALMFTR

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=231, Percent_Identity=40.6926406926407, Blast_Score=169, Evalue=3e-42,
Organism=Escherichia coli, GI1786943, Length=244, Percent_Identity=42.6229508196721, Blast_Score=185, Evalue=2e-48,
Organism=Escherichia coli, GI1790596, Length=236, Percent_Identity=38.135593220339, Blast_Score=159, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17533915, Length=244, Percent_Identity=39.344262295082, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6322987, Length=241, Percent_Identity=40.6639004149378, Blast_Score=184, Evalue=9e-48,
Organism=Drosophila melanogaster, GI17137106, Length=238, Percent_Identity=41.1764705882353, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24643156, Length=207, Percent_Identity=42.512077294686, Blast_Score=169, Evalue=2e-42,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29335; Mature: 29204

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEPDVETLDPPLPPVPDGAVMVTVKIARFNPDDPDAFAATGGWQSFRVPCLPSDRLLN
CCCCCCCHHCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEECCCCCCCCCCCCCHHHHHH
LLIYIKGYLDGTLTFRRSCAHGVCGSDAMRINGVNRLACKVLMRDLLPKKKGKSLTVTVE
HHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEE
PIRGLPVEKDLVVDMEPFFDAYRAIKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCA
CCCCCCCCCCEEEECHHHHHHHHHCCCEEEECCCCCHHHHHCCCCHHHCCCCCHHHHEEE
CCTTSCPVFWHEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCTE
HHCCCCCEEEECCCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCEEEECCCCCHH
SCPRGIEVTKAIQEVKRALMFTR
CCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVEPDVETLDPPLPPVPDGAVMVTVKIARFNPDDPDAFAATGGWQSFRVPCLPSDRLLN
CCCCCCHHCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEECCCCCCCCCCCCCHHHHHH
LLIYIKGYLDGTLTFRRSCAHGVCGSDAMRINGVNRLACKVLMRDLLPKKKGKSLTVTVE
HHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEE
PIRGLPVEKDLVVDMEPFFDAYRAIKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCA
CCCCCCCCCCEEEECHHHHHHHHHCCCEEEECCCCCHHHHHCCCCHHHCCCCCHHHHEEE
CCTTSCPVFWHEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCTE
HHCCCCCEEEECCCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCEEEECCCCCHH
SCPRGIEVTKAIQEVKRALMFTR
CCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]