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The map label for this gene is yfnA [H]

Identifier: 148824455

GI number: 148824455

Start: 3643875

End: 3645362

Strand: Reverse

Name: yfnA [H]

Synonym: TBFG_13282

Alternate gene names: 148824455

Gene position: 3645362-3643875 (Counterclockwise)

Preceding gene: 148824457

Following gene: 148824454

Centisome position: 82.39

GC content: 64.65

Gene sequence:

>1488_bases
ATGGCCGGTCGACGGCGCATGAAGTCGGTAGAACAGTCAATCGCCGACACCGACGAGCCCACCACTCGGCTGCGCAAGGA
CCTCACCTGGTGGGACCTGGTTGTTTTCGGCGTCTCGGTGGTGATTGGCGCCGGAATATTCACGGTTACCGCGTCGACCG
CTGGCGATATCACCGGCCCGGCCATCTGGATATCGTTTCTGATCGCGGCGGCGACCTGTGCGCTGGCCGCGCTGTGCTAC
GCCGAGTTCGCCTCGACGCTGCCGGTGGCCGGCAGCGCCTATACCTTCTCTTATGCCACCTTCGGGGAGTTCTTGGCCTG
GGTGATCGGCTGGAATCTGGTGCTGGAACTGGCGATGGGTGCGGCCGTGGTCGCCAAAGGCTGGTCCAGCTACTTGGGCA
CCGTGTTCGGATTCGGTAATGGCACAGGCCATCTCGGATCGCTGCAGCTCGACTGGGGTGCGCTCGTGATCGTCACGTTG
GTGGCGACCCTGATCGCGTTGGGCACCAAATTGTCGTCGAGATTTTCCGCGGTGGTCACCGCAATCAAGGTGTCGGTGGT
CGTCTTGGTGGTGGTCGTCGGTGCCTTCTACATCAGGGCCGCCAACTACTCGCCGTTCATTCCCGAGCCCGAAGTCCAGC
ACCACGGCGGCGGGCTCGATCAATCCGTCTTCTCGTTGCTGACCGGAGCCCAAGGCAGCCACTACGGATGGTACGGCGTG
CTGGCCGGGGCATCGATCGTGTTCTTCGCGTTTATCGGGTTTGACATCGTGGCCACCATGGCCGAGGAGACCAAGCGTCC
TCAACGAGACGTCCCTCGAGGGATTCTCGCGTCGCTGGGGGTCGTGACCCTTCTCTACGTCGCGGTATCGGTGGTGCTGT
CGGGCATGGTTCCATACACCCAACTGCGGACCGTACCGGGCCGCGGGCCGGCAAATCTGGCCACCGCGTTCCAGGCCAAC
GGGGTGTACTGGGCCAGCGGCATCATCTCCGTCGGCGCGCTGGCCGGGCTTACCACGGTGGTGATGGTGTTGATGCTCGG
GCAATGCCGCGTGCTGTTCGCCATGGCGCGCGACGGCTTGGTGCCGCGGCAATTGGCCAAGACCGGTTCGCGCGGCACCC
CGGTCCGGGTCACGGTGCTGGTCGCGGTGTTGGTGGCCACGACGGCGTCGGTGTTTCCGATCACCAAGCTTGAGGAGATG
GTCAACGTCGGGACACTGTTCGCGTTCATCCTCGTCTCGGCCGGAGTGGTCGTGCTGCGCCGGACCCGACCCGACCTTCA
GCGGGGGTTCACAGCTCCGTGGGTGCCGTTACTTCCGATCGCCGCAGTGTGCGCGTGCCTGTGGCTGATGCTGAACCTCA
CCGCGTTGACTTGGATCCGGTTCGGGATCTGGCTGGTGGCCGGAACCGCGATTTATGTCGGCTACGGGCGCCGGCACTCG
GCGCAGGGCCTTCGGCAAGCTCGAGAGAGCGCGACCCGGAGGTGTTGA

Upstream 100 bases:

>100_bases
CGATCACCACGGCGTGGTCCTTCGGGTTCCCTACGCGACCCGTCATCCTCGCAGAGTACCCAGTACTGTGCGGTCACAAC
GAGTGCGAGAGGACGGGTGC

Downstream 100 bases:

>100_bases
ACTAGCTTCGCCGCGTATTTACAAATTGCGTTATATGTCTAGACATAAGACGCAAACTGCTCTATTGTCAAATCCCAACG
TGGTGTGGCTCATGAGGAGG

Product: cationic amino acid transport integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MAGRRRMKSVEQSIADTDEPTTRLRKDLTWWDLVVFGVSVVIGAGIFTVTASTAGDITGPAIWISFLIAAATCALAALCY
AEFASTLPVAGSAYTFSYATFGEFLAWVIGWNLVLELAMGAAVVAKGWSSYLGTVFGFGNGTGHLGSLQLDWGALVIVTL
VATLIALGTKLSSRFSAVVTAIKVSVVVLVVVVGAFYIRAANYSPFIPEPEVQHHGGGLDQSVFSLLTGAQGSHYGWYGV
LAGASIVFFAFIGFDIVATMAEETKRPQRDVPRGILASLGVVTLLYVAVSVVLSGMVPYTQLRTVPGRGPANLATAFQAN
GVYWASGIISVGALAGLTTVVMVLMLGQCRVLFAMARDGLVPRQLAKTGSRGTPVRVTVLVAVLVATTASVFPITKLEEM
VNVGTLFAFILVSAGVVVLRRTRPDLQRGFTAPWVPLLPIAAVCACLWLMLNLTALTWIRFGIWLVAGTAIYVGYGRRHS
AQGLRQARESATRRC

Sequences:

>Translated_495_residues
MAGRRRMKSVEQSIADTDEPTTRLRKDLTWWDLVVFGVSVVIGAGIFTVTASTAGDITGPAIWISFLIAAATCALAALCY
AEFASTLPVAGSAYTFSYATFGEFLAWVIGWNLVLELAMGAAVVAKGWSSYLGTVFGFGNGTGHLGSLQLDWGALVIVTL
VATLIALGTKLSSRFSAVVTAIKVSVVVLVVVVGAFYIRAANYSPFIPEPEVQHHGGGLDQSVFSLLTGAQGSHYGWYGV
LAGASIVFFAFIGFDIVATMAEETKRPQRDVPRGILASLGVVTLLYVAVSVVLSGMVPYTQLRTVPGRGPANLATAFQAN
GVYWASGIISVGALAGLTTVVMVLMLGQCRVLFAMARDGLVPRQLAKTGSRGTPVRVTVLVAVLVATTASVFPITKLEEM
VNVGTLFAFILVSAGVVVLRRTRPDLQRGFTAPWVPLLPIAAVCACLWLMLNLTALTWIRFGIWLVAGTAIYVGYGRRHS
AQGLRQARESATRRC
>Mature_494_residues
AGRRRMKSVEQSIADTDEPTTRLRKDLTWWDLVVFGVSVVIGAGIFTVTASTAGDITGPAIWISFLIAAATCALAALCYA
EFASTLPVAGSAYTFSYATFGEFLAWVIGWNLVLELAMGAAVVAKGWSSYLGTVFGFGNGTGHLGSLQLDWGALVIVTLV
ATLIALGTKLSSRFSAVVTAIKVSVVVLVVVVGAFYIRAANYSPFIPEPEVQHHGGGLDQSVFSLLTGAQGSHYGWYGVL
AGASIVFFAFIGFDIVATMAEETKRPQRDVPRGILASLGVVTLLYVAVSVVLSGMVPYTQLRTVPGRGPANLATAFQANG
VYWASGIISVGALAGLTTVVMVLMLGQCRVLFAMARDGLVPRQLAKTGSRGTPVRVTVLVAVLVATTASVFPITKLEEMV
NVGTLFAFILVSAGVVVLRRTRPDLQRGFTAPWVPLLPIAAVCACLWLMLNLTALTWIRFGIWLVAGTAIYVGYGRRHSA
QGLRQARESATRRC

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI114326544, Length=438, Percent_Identity=37.2146118721461, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI114326550, Length=438, Percent_Identity=37.2146118721461, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI181337167, Length=424, Percent_Identity=36.0849056603774, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI258645169, Length=433, Percent_Identity=36.0277136258661, Blast_Score=219, Evalue=6e-57,
Organism=Homo sapiens, GI4507047, Length=435, Percent_Identity=34.4827586206897, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI258614003, Length=434, Percent_Identity=34.5622119815668, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI258614005, Length=434, Percent_Identity=34.7926267281106, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI110347453, Length=430, Percent_Identity=34.1860465116279, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI187423910, Length=452, Percent_Identity=23.4513274336283, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI7657591, Length=452, Percent_Identity=23.4513274336283, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI115648063, Length=382, Percent_Identity=23.8219895287958, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI115648022, Length=382, Percent_Identity=23.8219895287958, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87081869, Length=452, Percent_Identity=24.7787610619469, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790653, Length=442, Percent_Identity=23.3031674208145, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786602, Length=379, Percent_Identity=21.8997361477573, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786302, Length=411, Percent_Identity=24.5742092457421, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786694, Length=404, Percent_Identity=22.2772277227723, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081708, Length=448, Percent_Identity=20.5357142857143, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081915, Length=399, Percent_Identity=25.31328320802, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87082023, Length=461, Percent_Identity=23.2104121475054, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788480, Length=440, Percent_Identity=22.5, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=415, Percent_Identity=38.7951807228916, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17531343, Length=436, Percent_Identity=34.4036697247706, Blast_Score=202, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17533459, Length=444, Percent_Identity=31.7567567567568, Blast_Score=182, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17537453, Length=356, Percent_Identity=24.1573033707865, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193208714, Length=365, Percent_Identity=22.1917808219178, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32566695, Length=367, Percent_Identity=22.3433242506812, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221512776, Length=434, Percent_Identity=35.2534562211982, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24666159, Length=434, Percent_Identity=35.2534562211982, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24667468, Length=443, Percent_Identity=37.020316027088, Blast_Score=241, Evalue=8e-64,
Organism=Drosophila melanogaster, GI24668806, Length=429, Percent_Identity=34.032634032634, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI21356285, Length=429, Percent_Identity=34.032634032634, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI24668802, Length=429, Percent_Identity=34.032634032634, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI161077963, Length=427, Percent_Identity=34.8946135831382, Blast_Score=199, Evalue=5e-51,
Organism=Drosophila melanogaster, GI281366235, Length=426, Percent_Identity=34.7417840375587, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI116007820, Length=426, Percent_Identity=34.7417840375587, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI116007818, Length=427, Percent_Identity=34.6604215456674, Blast_Score=195, Evalue=8e-50,
Organism=Drosophila melanogaster, GI85725152, Length=427, Percent_Identity=34.6604215456674, Blast_Score=195, Evalue=8e-50,
Organism=Drosophila melanogaster, GI21357367, Length=496, Percent_Identity=22.3790322580645, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45550968, Length=496, Percent_Identity=23.7903225806452, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19921172, Length=496, Percent_Identity=23.7903225806452, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221331183, Length=450, Percent_Identity=23.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17647653, Length=450, Percent_Identity=23.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24664379, Length=450, Percent_Identity=23.3333333333333, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52520; Mature: 52389

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGRRRMKSVEQSIADTDEPTTRLRKDLTWWDLVVFGVSVVIGAGIFTVTASTAGDITGP
CCHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCHHHEEECCCCCCCCHH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HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]