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The map label for this gene is 148824142

Identifier: 148824142

GI number: 148824142

Start: 3316752

End: 3318008

Strand: Direct

Name: 148824142

Synonym: TBFG_12967

Alternate gene names: NA

Gene position: 3316752-3318008 (Clockwise)

Preceding gene: 148824141

Following gene: 148824145

Centisome position: 74.96

GC content: 64.84

Gene sequence:

>1257_bases
ATGAGCCCAGCTGAGCGCGAGTTCGACATCGTTCTATATGGCGCCACCGGCTTCTCCGGCAAGCTGACCGCCGAACACCT
CGCTCACAGCGGGTCAACAGCACGGATCGCATTGGCCGGTCGGTCAAGCGAACGGCTGCGGGGCGTGCGGATGATGTTGG
GCCCGAACGCAGCGGACTGGCCGCTGATCCTCGCCGACGCATCCCAACCCTTGACGCTCGAGGCGATGGCCGCGCGGGCC
CAGGTGGTGCTGACCACGGTCGGCCCCTACACGCGTTACGGCCTGCCGCTGGTGGCGGCCTGCGCGAAGGCCGGAACCGA
CTATGCCGACCTGACTGGCGAGTTGATGTTCTGCCGAAACAGCATCGATCTGTACCACAAACAAGCCGCCGACACGGGCG
CCCGGATAATCCTGGCGTGCGGATTCGATTCGATCCCTTCGGATTTGAACGTGTATCAGCTGTACCGTCGGTCCGTCGAG
GACGGCACCGGTGAACTGTGTGACACCGACCTCGTGCTGCGTTCATTCTCGCAACGCTGGGTCTCCGGCGGCTCGGTAGC
AACGTATTCCGAAGCAATGCGCACGGCATCCAGCGACCCCGAGGCCCGTCGGCTCGTCACCGACCCGTACACGCTGACCA
CGGACCGGGGCGCCGAACCCGAACTTGGTGCGCAGCCGGATTTTCTTCGGCGTCCAGGACGTGATCTGGCGCCCGAACTT
GCCGGCTTCTGGACCGGCGGGTTTGTGCAGGCTCCGTTTAACACTCGAATCGTTCGGCGTAGCAACGCATTACAGGAGTG
GGCTTATGGCCGGCGGTTCCGCTACTCGGAAACAATGAGTCTGGGAAAGTCGATGGCGGCGCCGATTCTCGCCGCAGCCG
TCACCGGCACTGTGGCGGGCACCATCGGGTTGGGGAATAAGTATTTCGACCGACTACCCCGACGATTAGTGGAGCGCGTC
ACGCCAAAGCCAGGCACCGGTCCGAGCCGGAAAACGCAAGAGCGGGGCCATTACACCTTCGAGACGTACACCACCACGAC
GACCGGTGCCCGCTACAGGGCGACTTTCGCGCACAACGTCGACGCGTACAAGTCGACCGCGGTGTTGCTCGCGCAGAGTG
GTCTGGCGCTGGCGCTCGATCGCGATCGGCTCGCCGAGCTGCGGGGGGTGCTCACTCCCGCAGCGGCGATGGGCGATGCG
TTGTTGGCGCGCCTCCCGGGCGCCGGCGTGGTCATGGGAACGACCAGGCTGAGCTAA

Upstream 100 bases:

>100_bases
CAGGGCACGCAGCTGTCCCGCTACCTGGAAGGCGGGGAACTCTCGTACCGGATGTACTGCTTCACCAAGGACTGAGCCAG
TTTCGGGTAATGTCGCCCGG

Downstream 100 bases:

>100_bases
CATCTCCACCCCGGCCGCCAGCAAGATTAGCTATGCCATGGGCACATTAGCCCAATCCTGTTCTCCCAGATCTGGGCCTT
TGCCGCCGAGAATCAAACTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSPAEREFDIVLYGATGFSGKLTAEHLAHSGSTARIALAGRSSERLRGVRMMLGPNAADWPLILADASQPLTLEAMAARA
QVVLTTVGPYTRYGLPLVAACAKAGTDYADLTGELMFCRNSIDLYHKQAADTGARIILACGFDSIPSDLNVYQLYRRSVE
DGTGELCDTDLVLRSFSQRWVSGGSVATYSEAMRTASSDPEARRLVTDPYTLTTDRGAEPELGAQPDFLRRPGRDLAPEL
AGFWTGGFVQAPFNTRIVRRSNALQEWAYGRRFRYSETMSLGKSMAAPILAAAVTGTVAGTIGLGNKYFDRLPRRLVERV
TPKPGTGPSRKTQERGHYTFETYTTTTTGARYRATFAHNVDAYKSTAVLLAQSGLALALDRDRLAELRGVLTPAAAMGDA
LLARLPGAGVVMGTTRLS

Sequences:

>Translated_418_residues
MSPAEREFDIVLYGATGFSGKLTAEHLAHSGSTARIALAGRSSERLRGVRMMLGPNAADWPLILADASQPLTLEAMAARA
QVVLTTVGPYTRYGLPLVAACAKAGTDYADLTGELMFCRNSIDLYHKQAADTGARIILACGFDSIPSDLNVYQLYRRSVE
DGTGELCDTDLVLRSFSQRWVSGGSVATYSEAMRTASSDPEARRLVTDPYTLTTDRGAEPELGAQPDFLRRPGRDLAPEL
AGFWTGGFVQAPFNTRIVRRSNALQEWAYGRRFRYSETMSLGKSMAAPILAAAVTGTVAGTIGLGNKYFDRLPRRLVERV
TPKPGTGPSRKTQERGHYTFETYTTTTTGARYRATFAHNVDAYKSTAVLLAQSGLALALDRDRLAELRGVLTPAAAMGDA
LLARLPGAGVVMGTTRLS
>Mature_417_residues
SPAEREFDIVLYGATGFSGKLTAEHLAHSGSTARIALAGRSSERLRGVRMMLGPNAADWPLILADASQPLTLEAMAARAQ
VVLTTVGPYTRYGLPLVAACAKAGTDYADLTGELMFCRNSIDLYHKQAADTGARIILACGFDSIPSDLNVYQLYRRSVED
GTGELCDTDLVLRSFSQRWVSGGSVATYSEAMRTASSDPEARRLVTDPYTLTTDRGAEPELGAQPDFLRRPGRDLAPELA
GFWTGGFVQAPFNTRIVRRSNALQEWAYGRRFRYSETMSLGKSMAAPILAAAVTGTVAGTIGLGNKYFDRLPRRLVERVT
PKPGTGPSRKTQERGHYTFETYTTTTTGARYRATFAHNVDAYKSTAVLLAQSGLALALDRDRLAELRGVLTPAAAMGDAL
LARLPGAGVVMGTTRLS

Specific function: Involved in the reduction of the double bond between C-4 and C-5 during phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily

Homologues:

Organism=Homo sapiens, GI55770836, Length=449, Percent_Identity=27.3942093541203, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI32567112, Length=150, Percent_Identity=36.6666666666667, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17560066, Length=150, Percent_Identity=36.6666666666667, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71991033, Length=159, Percent_Identity=32.0754716981132, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24646278, Length=152, Percent_Identity=34.2105263157895, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24644140, Length=148, Percent_Identity=33.1081081081081, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24644142, Length=148, Percent_Identity=33.1081081081081, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21356081, Length=148, Percent_Identity=33.1081081081081, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAER_MYCBO (Q7TXK2)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856622.1
- ProteinModelPortal:   Q7TXK2
- EnsemblBacteria:   EBMYCT00000015719
- GeneID:   1092128
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2977
- GeneTree:   EBGT00050000017653
- HOGENOM:   HBG527018
- OMA:   EEMATRA
- ProtClustDB:   CLSK2748649
- BioCyc:   MBOV233413:MB2977-MONOMER
- GO:   GO:0005488
- InterPro:   IPR016040
- InterPro:   IPR005097
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF03435 Saccharop_dh

EC number: NA

Molecular weight: Translated: 45105; Mature: 44974

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAEREFDIVLYGATGFSGKLTAEHLAHSGSTARIALAGRSSERLRGVRMMLGPNAADW
CCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHEEECCCCCCC
PLILADASQPLTLEAMAARAQVVLTTVGPYTRYGLPLVAACAKAGTDYADLTGELMFCRN
CEEEECCCCCEEHHHHHCCEEEEEEECCCHHHHCCHHHHHHHHCCCCHHHHCCEEEEEEC
SIDLYHKQAADTGARIILACGFDSIPSDLNVYQLYRRSVEDGTGELCDTDLVLRSFSQRW
CHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VSGGSVATYSEAMRTASSDPEARRLVTDPYTLTTDRGAEPELGAQPDFLRRPGRDLAPEL
CCCCCCHHHHHHHHHCCCCCHHHHEECCCEEEECCCCCCCCCCCCCHHHHCCCCCCCHHH
AGFWTGGFVQAPFNTRIVRRSNALQEWAYGRRFRYSETMSLGKSMAAPILAAAVTGTVAG
HHHCCCCEEECCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEE
TIGLGNKYFDRLPRRLVERVTPKPGTGPSRKTQERGHYTFETYTTTTTGARYRATFAHNV
EECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCEEEEEEEEECCCCEEEEEECCCC
DAYKSTAVLLAQSGLALALDRDRLAELRGVLTPAAAMGDALLARLPGAGVVMGTTRLS
HHHHHHEEEEECCCCEEEECHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEECCCC
>Mature Secondary Structure 
SPAEREFDIVLYGATGFSGKLTAEHLAHSGSTARIALAGRSSERLRGVRMMLGPNAADW
CCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHEEECCCCCCC
PLILADASQPLTLEAMAARAQVVLTTVGPYTRYGLPLVAACAKAGTDYADLTGELMFCRN
CEEEECCCCCEEHHHHHCCEEEEEEECCCHHHHCCHHHHHHHHCCCCHHHHCCEEEEEEC
SIDLYHKQAADTGARIILACGFDSIPSDLNVYQLYRRSVEDGTGELCDTDLVLRSFSQRW
CHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VSGGSVATYSEAMRTASSDPEARRLVTDPYTLTTDRGAEPELGAQPDFLRRPGRDLAPEL
CCCCCCHHHHHHHHHCCCCCHHHHEECCCEEEECCCCCCCCCCCCCHHHHCCCCCCCHHH
AGFWTGGFVQAPFNTRIVRRSNALQEWAYGRRFRYSETMSLGKSMAAPILAAAVTGTVAG
HHHCCCCEEECCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEE
TIGLGNKYFDRLPRRLVERVTPKPGTGPSRKTQERGHYTFETYTTTTTGARYRATFAHNV
EECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCEEEEEEEEECCCCEEEEEECCCC
DAYKSTAVLLAQSGLALALDRDRLAELRGVLTPAAAMGDALLARLPGAGVVMGTTRLS
HHHHHHEEEEECCCCEEEECHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972