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The map label for this gene is xerC

Identifier: 148824083

GI number: 148824083

Start: 3214923

End: 3215819

Strand: Reverse

Name: xerC

Synonym: TBFG_12908

Alternate gene names: 148824083

Gene position: 3215819-3214923 (Counterclockwise)

Preceding gene: 148824084

Following gene: 148824081

Centisome position: 72.68

GC content: 70.79

Gene sequence:

>897_bases
GTGCAGGCGATCCTTGACGAGTTCGACGAATACCTTGCCCTGCAATGCGGTCGGTCGGTGCACACCCGTCGTGCCTACCT
GGGCGATCTAAGATCGCTCTTCGCGTTTCTCGCCGATCGCGGATCGAGTCTGGACGCACTAACCCTTTCGGTCCTGCGGT
CTTGGCTGGCCGCGACGGCGGGAGCGGGCGCCGCCCGCACGACGCTGGCGCGGCGCACTTCGGCGGTTAAGGCATTCACC
GCCTGGGCGGTGCGGCGCGGGCTACTGGCCGGTGATCCTGCGGCCCGGCTACAGGTGCCGAAGGCCCGTCGCACCTTGCC
GGCGGTGCTGCGTCAGGATCAGGCGCTGCGCGCCATGGCGGCTGCCGAATCTGGTGCAGAGCAAGGTGATCCGCTAGCGC
TGCGGGACCGGTTGATCGTCGAGCTGTTGTACGCCACCGGTATCCGGGTCAGCGAGCTGTGCGGCCTGGACGTCGACGAC
ATCGACACCGGCCATCGGTTGGTTCGGGTGCTCGGCAAGGGCAACAAGCAGCGCACCGTCCCGTTCGGGCAGCCAGCCGC
CGATGCGCTGCACGCCTGGCTGGTCGACGGCCGTCGCGCGCTGGTCACCGCGGAGTCCGGGCACGCGCTGCTGCTGGGTG
CCCGGGGCCGGCGCCTTGACGTGCGGCAAGCACGCACTGCGGTGCACCAGACCGTGGCCGCGGTGGACGGCGCACCCGAT
ATGGGGCCGCACGGGCTGCGGCACAGCGCGGCGACCCACCTGCTGGAAGGTGGCGCCGACCTGCGGGTGGTCCAGGAGCT
GCTCGGTCATTCCAGCCTGGCGACCACGCAGCTGTACACCCACGTCGCGGTCGCCCGGTTGCGGGCGGTGCACGAGCGGG
CCCATCCGCGGGCCTAG

Upstream 100 bases:

>100_bases
GACTCACTAGGTCGGCTATCCCAGGCCGAAAGATCTCACCCCGGACACGGTGCGGCGCGTCGACTCGGGCTCGAGACGTC
ATGCCTGCGACTGTGGGGGA

Downstream 100 bases:

>100_bases
CCGTAGCGCAGGAGCGCGATGACCTCGGCGATGTCGCGCATTGCCGACGCGCGGCCAGCCCACTCGTCGAACACCGTCCA
ATAGCTGACACCGAACCGCC

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAFT
AWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDD
IDTGHRLVRVLGKGNKQRTVPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVHQTVAAVDGAPD
MGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA

Sequences:

>Translated_298_residues
MQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAFT
AWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDD
IDTGHRLVRVLGKGNKQRTVPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVHQTVAAVDGAPD
MGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA
>Mature_298_residues
MQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAFT
AWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDD
IDTGHRLVRVLGKGNKQRTVPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVHQTVAAVDGAPD
MGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=297, Percent_Identity=40.7407407407407, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=35.2542372881356, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1790767, Length=181, Percent_Identity=29.8342541436464, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790768, Length=162, Percent_Identity=30.2469135802469, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_MYCBO (P67629)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856563.1
- ProteinModelPortal:   P67629
- SMR:   P67629
- EnsemblBacteria:   EBMYCT00000014908
- GeneID:   1092189
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2918c
- GeneTree:   EBGT00050000015380
- HOGENOM:   HBG727654
- OMA:   MERFIEY
- ProtClustDB:   PRK00236
- BioCyc:   MBOV233413:MB2918C-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 31980; Mature: 31980

Theoretical pI: Translated: 10.99; Mature: 10.99

Prosite motif: NA

Important sites: ACT_SITE 149-149 ACT_SITE 173-173 ACT_SITE 244-244 ACT_SITE 247-247 ACT_SITE 270-270 ACT_SITE 279-279

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLDALTLSVLRSWLAATA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GAGAARTTLARRTSAVKAFTAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHH
AAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRTV
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCC
PFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVHQTVAAVDGAPD
CCCCHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
MGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLDALTLSVLRSWLAATA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GAGAARTTLARRTSAVKAFTAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECCHHHHHHHHHHHHHHHHHHHH
AAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRTV
HHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCC
PFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVHQTVAAVDGAPD
CCCCHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCC
MGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972