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The map label for this gene is ppe45

Identifier: 148824081

GI number: 148824081

Start: 3212323

End: 3213549

Strand: Reverse

Name: ppe45

Synonym: TBFG_12906

Alternate gene names: 148824081

Gene position: 3213549-3212323 (Counterclockwise)

Preceding gene: 148824083

Following gene: 148824079

Centisome position: 72.63

GC content: 67.89

Gene sequence:

>1227_bases
TTGGACTTTGGGGTGTTGCCGCCCGAGATCAACTCCGGTCGAATGTACGCAGGTCCGGGATCGGGGCCCATGATGGCCGC
CGCGGCGGCCTGGGATAGTTTGGCGGCTGAATTGGGCTTGGCCGCCGGCGGCTACCGGTTGGCTATCTCGGAGCTGACCG
GTGCGTACTGGGCGGGGCCCGCAGCGGCGTCGATGGTGGCCGCGGTCACGCCTTATGTGGCGTGGCTCAGCGCCACCGCC
GGTCAGGCTGAACAGGCGGGCATGCAGGCCAGAGCGGCCGCGGCAGCCTATGAGCTGGCGTTTGCGATGACGGTGCCCCC
GCCGGTGGTCGTTGCCAACCGCGCGCTGTTGGTGGCGCTGGTCGCGACCAACTTTTTCGGGCAGAACACCCCGGCGATCG
CGGCCACCGAGGCCCAATACGCCGAGATGTGGGCCCAAGACGCTGCCGCCATGTACGCCTATGCGGGCTCCGCGGCAATC
GCCACGGAGTTGACCCCGTTCACCGCGGCGCCAGTGACTACCAGCCCTGCCGCGCTGGCCGGCCAGGCGGCGGCGACGGT
ATCGTCGACGGTCCCACCGCTGGCCACCACCGCCGCGGTGCCCCAACTGTTGCAGCAACTCTCGTCGACGTCACTGATCC
CGTGGTACTCGGCATTGCAGCAATGGCTCGCGGAGAATCTTCTCGGTCTCACGCCTGACAACAGGATGACGATCGTTCGG
TTGCTGGGCATCAGCTACTTCGACGAAGGGCTACTGCAATTCGAGGCTTCGCTCGCCCAGCAAGCGATCCCGGGCACCCC
GGGCGGCGCCGGTGACTCGGGATCCTCGGTGCTTGACAGCTGGGGTCCAACCATCTTCGCCGGCCCGCGGGCGAGCCCAA
GTGTGGCAGGCGGCGGTGCTGTTGGCGGGGTTCAGACGCCCCAGCCGTACTGGTACTGGGCACTAGACCGAGAAAGCATT
GGCGGATCGGTATCGGCCGCTTTGGGGAAGGGGAGCTCGGCTGGTTCATTGTCGGTGCCACCCGATTGGGCCGCCCGCGC
TCGATGGGCAAACCCAGCGGCCTGGCGGTTGCCGGGCGACGATGTCACCGCCCTGCGCGGCACCGCGGAAAACGCCCTGC
TTCGGGGATTTCCGATGGCCAGCGCCGGCCAGAGCACCGGCGGCGGCTTCGTTCACAAATACGGGTTCCGCTTGGCGGTA
ATGCAGCGTCCGCCCTTCGCTGGATAG

Upstream 100 bases:

>100_bases
GCGATTCAAGACCAGTTCGTGACCGCATCACGTACCACTGCCTATTCGGGTGGGGCGCGTAACCACGCCGTGATCCCGGC
CGGCTAGGGAGGGATGGGCG

Downstream 100 bases:

>100_bases
CGGCTTGAGCCGTATCGGTGTGGACTTCAGCAGGCCCAGCGGATCGACATAGTTGGCGCCCGAAGCCGGGCCCCACATCG
CCCCCCAGTGCAGACAGGCG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MDFGVLPPEINSGRMYAGPGSGPMMAAAAAWDSLAAELGLAAGGYRLAISELTGAYWAGPAAASMVAAVTPYVAWLSATA
GQAEQAGMQARAAAAAYELAFAMTVPPPVVVANRALLVALVATNFFGQNTPAIAATEAQYAEMWAQDAAAMYAYAGSAAI
ATELTPFTAAPVTTSPAALAGQAAATVSSTVPPLATTAAVPQLLQQLSSTSLIPWYSALQQWLAENLLGLTPDNRMTIVR
LLGISYFDEGLLQFEASLAQQAIPGTPGGAGDSGSSVLDSWGPTIFAGPRASPSVAGGGAVGGVQTPQPYWYWALDRESI
GGSVSAALGKGSSAGSLSVPPDWAARARWANPAAWRLPGDDVTALRGTAENALLRGFPMASAGQSTGGGFVHKYGFRLAV
MQRPPFAG

Sequences:

>Translated_408_residues
MDFGVLPPEINSGRMYAGPGSGPMMAAAAAWDSLAAELGLAAGGYRLAISELTGAYWAGPAAASMVAAVTPYVAWLSATA
GQAEQAGMQARAAAAAYELAFAMTVPPPVVVANRALLVALVATNFFGQNTPAIAATEAQYAEMWAQDAAAMYAYAGSAAI
ATELTPFTAAPVTTSPAALAGQAAATVSSTVPPLATTAAVPQLLQQLSSTSLIPWYSALQQWLAENLLGLTPDNRMTIVR
LLGISYFDEGLLQFEASLAQQAIPGTPGGAGDSGSSVLDSWGPTIFAGPRASPSVAGGGAVGGVQTPQPYWYWALDRESI
GGSVSAALGKGSSAGSLSVPPDWAARARWANPAAWRLPGDDVTALRGTAENALLRGFPMASAGQSTGGGFVHKYGFRLAV
MQRPPFAG
>Mature_408_residues
MDFGVLPPEINSGRMYAGPGSGPMMAAAAAWDSLAAELGLAAGGYRLAISELTGAYWAGPAAASMVAAVTPYVAWLSATA
GQAEQAGMQARAAAAAYELAFAMTVPPPVVVANRALLVALVATNFFGQNTPAIAATEAQYAEMWAQDAAAMYAYAGSAAI
ATELTPFTAAPVTTSPAALAGQAAATVSSTVPPLATTAAVPQLLQQLSSTSLIPWYSALQQWLAENLLGLTPDNRMTIVR
LLGISYFDEGLLQFEASLAQQAIPGTPGGAGDSGSSVLDSWGPTIFAGPRASPSVAGGGAVGGVQTPQPYWYWALDRESI
GGSVSAALGKGSSAGSLSVPPDWAARARWANPAAWRLPGDDVTALRGTAENALLRGFPMASAGQSTGGGFVHKYGFRLAV
MQRPPFAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE45_MYCBO (P0A695)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856561.1
- ProteinModelPortal:   P0A695
- SMR:   P0A695
- EnsemblBacteria:   EBMYCT00000016099
- GeneID:   1092191
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2916c
- GeneTree:   EBGT00050000014887
- HOGENOM:   HBG572308
- OMA:   SARIYTG
- ProtClustDB:   CLSK799939
- BioCyc:   MBOV233413:MB2916C-MONOMER
- InterPro:   IPR022171
- InterPro:   IPR000030

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE

EC number: NA

Molecular weight: Translated: 41469; Mature: 41469

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c4a349c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFGVLPPEINSGRMYAGPGSGPMMAAAAAWDSLAAELGLAAGGYRLAISELTGAYWAGP
CCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCH
AAASMVAAVTPYVAWLSATAGQAEQAGMQARAAAAAYELAFAMTVPPPVVVANRALLVAL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHH
VATNFFGQNTPAIAATEAQYAEMWAQDAAAMYAYAGSAAIATELTPFTAAPVTTSPAALA
HHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCCCCHHHH
GQAAATVSSTVPPLATTAAVPQLLQQLSSTSLIPWYSALQQWLAENLLGLTPDNRMTIVR
CHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHH
LLGISYFDEGLLQFEASLAQQAIPGTPGGAGDSGSSVLDSWGPTIFAGPRASPSVAGGGA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCCCCCCC
VGGVQTPQPYWYWALDRESIGGSVSAALGKGSSAGSLSVPPDWAARARWANPAAWRLPGD
CCCCCCCCCCEEEEEEHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCC
DVTALRGTAENALLRGFPMASAGQSTGGGFVHKYGFRLAVMQRPPFAG
CCHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCH
>Mature Secondary Structure
MDFGVLPPEINSGRMYAGPGSGPMMAAAAAWDSLAAELGLAAGGYRLAISELTGAYWAGP
CCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCH
AAASMVAAVTPYVAWLSATAGQAEQAGMQARAAAAAYELAFAMTVPPPVVVANRALLVAL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHH
VATNFFGQNTPAIAATEAQYAEMWAQDAAAMYAYAGSAAIATELTPFTAAPVTTSPAALA
HHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCCCCHHHH
GQAAATVSSTVPPLATTAAVPQLLQQLSSTSLIPWYSALQQWLAENLLGLTPDNRMTIVR
CHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHH
LLGISYFDEGLLQFEASLAQQAIPGTPGGAGDSGSSVLDSWGPTIFAGPRASPSVAGGGA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCCCCCCC
VGGVQTPQPYWYWALDRESIGGSVSAALGKGSSAGSLSVPPDWAARARWANPAAWRLPGD
CCCCCCCCCCEEEEEEHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCC
DVTALRGTAENALLRGFPMASAGQSTGGGFVHKYGFRLAVMQRPPFAG
CCHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972