| Definition | Mycobacterium tuberculosis F11, complete genome. |
|---|---|
| Accession | NC_009565 |
| Length | 4,424,435 |
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The map label for this gene is fabG [H]
Identifier: 148824048
GI number: 148824048
Start: 3180221
End: 3180997
Strand: Reverse
Name: fabG [H]
Synonym: TBFG_12873
Alternate gene names: 148824048
Gene position: 3180997-3180221 (Counterclockwise)
Preceding gene: 148824049
Following gene: 148824042
Centisome position: 71.9
GC content: 63.71
Gene sequence:
>777_bases GTGATGGACCTCAGCCAACGGCTGGCCGGCCGGGTGGCGGTGATCACAGGCGGTGGCAGCGGTATTGGCCTGGCTGCCGG CCGTCGGATGCGGGCGGAAGGCGCCACGATCGTGGTCGGCGACGTCGACGTCGAGGCCGGTGGTGCGGCCGCTGACGAAC TATCAGGCTTGTTTGTGCCAACCGACGTTTGCGATGAGGACGCCGTCAACGGGCTGTTCGACGGAGCAGCCGAAACCTAC GGCCGCATAGATATTGCGTTCAACAACGCCGGCATCTCACCACCCGAGGACAATCTGATCGAAAACACCGAGCTCGCGGC GTGGCAACGGGTACAAGACGTCAACCTGAAGTCGGTGTACTTGTGCTGCCGGGCGGCCCTGCGCCACATGGTGCTTGCTG GGAAAGGCTCCATCGTCAACACGGCGTCCTTCGTTGCGGTGATGGGTTCGGCAACGTCGCAGATCTCCTACACCGCCTCC AAGGGTGGAGTGCTGGCTATGTCACGGGAACTGGGCGTGCAATTCGCTCGGCAGGGCATCCGGGTCAACGCGTTGTGCCC GGGGCCGGTGAACACCCCACTGCTGCAAGAGCTTTTCGCCAAGAACCCGGAACGGGCCGCTCGCCGCATGGTGCATGTGC CGCTGGGCCGGTTCGCCGAGCCCGACGAAATTGCTGCTGCGGTAGCGTTTTTAGCCAGCGACGACGCATCATTCATCACC GCTTCGACGTTCCTGGTCGACGGTGGGATCAGCTCGGCCTATGTCACTCCGCTGTGA
Upstream 100 bases:
>100_bases GCGGTTTCAAGCAGTCCGGTGTGGGCCGCGAGCTAGGGCCGGACGCTCCGCTGCAGTTCACCGAAACCAAAAATGTGTTC ATCGCCGTCGGGGAGGAGAT
Downstream 100 bases:
>100_bases TCGCGCCCCGAGTGTGAACTGCGCAACGGGTTAGCGTGTCGCGTAGTGCATTTCACAGTCGGATTGCTGTCAGGCCCGGA AGACGATCAACGTTGTCCAT
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 258; Mature: 258
Protein sequence:
>258_residues MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVVGDVDVEAGGAAADELSGLFVPTDVCDEDAVNGLFDGAAETY GRIDIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAGKGSIVNTASFVAVMGSATSQISYTAS KGGVLAMSRELGVQFARQGIRVNALCPGPVNTPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVAFLASDDASFIT ASTFLVDGGISSAYVTPL
Sequences:
>Translated_258_residues MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVVGDVDVEAGGAAADELSGLFVPTDVCDEDAVNGLFDGAAETY GRIDIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAGKGSIVNTASFVAVMGSATSQISYTAS KGGVLAMSRELGVQFARQGIRVNALCPGPVNTPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVAFLASDDASFIT ASTFLVDGGISSAYVTPL >Mature_258_residues MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVVGDVDVEAGGAAADELSGLFVPTDVCDEDAVNGLFDGAAETY GRIDIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAGKGSIVNTASFVAVMGSATSQISYTAS KGGVLAMSRELGVQFARQGIRVNALCPGPVNTPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVAFLASDDASFIT ASTFLVDGGISSAYVTPL
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=37.3333333333333, Blast_Score=129, Evalue=3e-30, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=35.3909465020576, Blast_Score=127, Evalue=8e-30, Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=31.9391634980989, Blast_Score=123, Evalue=1e-28, Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=32.9365079365079, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=31.4516129032258, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=29.4573643410853, Blast_Score=110, Evalue=9e-25, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=34.7490347490347, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=31.8627450980392, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI83715985, Length=259, Percent_Identity=32.8185328185328, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=30.8300395256917, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=32.5396825396825, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=30.1204819277108, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=29.9212598425197, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI109715829, Length=246, Percent_Identity=26.8292682926829, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI4504505, Length=192, Percent_Identity=28.6458333333333, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI4503301, Length=255, Percent_Identity=30.1960784313725, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=30.2325581395349, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI209862901, Length=207, Percent_Identity=29.4685990338164, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI19923983, Length=207, Percent_Identity=29.4685990338164, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=31.4720812182741, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=31.5217391304348, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI7706318, Length=205, Percent_Identity=26.3414634146341, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=34.8360655737705, Blast_Score=129, Evalue=1e-31, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=33.201581027668, Blast_Score=126, Evalue=1e-30, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=33.0645161290323, Blast_Score=120, Evalue=7e-29, Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=31.7647058823529, Blast_Score=110, Evalue=8e-26, Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=30, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=28.6852589641434, Blast_Score=98, Evalue=4e-22, Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=27.9352226720648, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=29.9212598425197, Blast_Score=91, Evalue=5e-20, Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=27.734375, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=28.2258064516129, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=31.3253012048193, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=28.0769230769231, Blast_Score=71, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=36.2549800796813, Blast_Score=128, Evalue=2e-30, Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=30.1960784313725, Blast_Score=126, Evalue=1e-29, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=29.7619047619048, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=34.251968503937, Blast_Score=124, Evalue=5e-29, Organism=Caenorhabditis elegans, GI17544670, Length=275, Percent_Identity=30.1818181818182, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=30.0395256916996, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=27.6923076923077, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=28.8461538461538, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=26.8939393939394, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=27.7566539923954, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=27.1698113207547, Blast_Score=97, Evalue=5e-21, Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=31.4176245210728, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=29.277566539924, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=27.8195488721804, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=30.6201550387597, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=27.8195488721804, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=25.2788104089219, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=28.030303030303, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=27.0676691729323, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=29.5275590551181, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=24.8091603053435, Blast_Score=88, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=26.1363636363636, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=27.4436090225564, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=24.6212121212121, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=27.1653543307087, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI115534694, Length=166, Percent_Identity=34.9397590361446, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=25.9398496240602, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=29.7435897435897, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17561272, Length=194, Percent_Identity=30.4123711340206, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193203117, Length=204, Percent_Identity=25.9803921568627, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI193203115, Length=207, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17555612, Length=213, Percent_Identity=26.7605633802817, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=24.1206030150754, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71982365, Length=195, Percent_Identity=29.2307692307692, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=30.6878306878307, Blast_Score=77, Evalue=3e-15, Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=26.4822134387352, Blast_Score=69, Evalue=1e-12, Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=36.9230769230769, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=29.5275590551181, Blast_Score=116, Evalue=2e-26, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=34.6456692913386, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=32.6693227091633, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=33.984375, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=33.6032388663968, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI17737361, Length=231, Percent_Identity=32.034632034632, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI24644337, Length=177, Percent_Identity=37.8531073446328, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI18859837, Length=255, Percent_Identity=30.1960784313725, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI281364892, Length=223, Percent_Identity=28.2511210762332, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI281364494, Length=210, Percent_Identity=31.4285714285714, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24641232, Length=226, Percent_Identity=29.2035398230088, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24665243, Length=201, Percent_Identity=29.8507462686567, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=29.8507462686567, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24665247, Length=203, Percent_Identity=30.0492610837438, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221331216, Length=203, Percent_Identity=30.0492610837438, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007234, Length=241, Percent_Identity=29.045643153527, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26805; Mature: 26805
Theoretical pI: Translated: 4.57; Mature: 4.57
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVVGDVDVEAGGAAADELSGLFVP CCCHHHHHCCEEEEEECCCCCEEHHCCCEEECCCCEEEEECCEECCCCCCHHHCCCEEEE TDVCDEDAVNGLFDGAAETYGRIDIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVY CCCCCHHHHHHHHCCHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHH LCCRAALRHMVLAGKGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGI HHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCEEEEECCCCCEEEEHHHHHHHHHHCCC RVNALCPGPVNTPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVAFLASDDASFIT EEEEECCCCCCCHHHHHHHHCCHHHHHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCEEE ASTFLVDGGISSAYVTPL EEEEEEECCCCCEEECCC >Mature Secondary Structure MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVVGDVDVEAGGAAADELSGLFVP CCCHHHHHCCEEEEEECCCCCEEHHCCCEEECCCCEEEEECCEECCCCCCHHHCCCEEEE TDVCDEDAVNGLFDGAAETYGRIDIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVY CCCCCHHHHHHHHCCHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHH LCCRAALRHMVLAGKGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGI HHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCEEEEECCCCCEEEEHHHHHHHHHHCCC RVNALCPGPVNTPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVAFLASDDASFIT EEEEECCCCCCCHHHHHHHHCCHHHHHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCEEE ASTFLVDGGISSAYVTPL EEEEEEECCCCCEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]