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The map label for this gene is mqo

Identifier: 148824042

GI number: 148824042

Start: 3172218

End: 3173699

Strand: Reverse

Name: mqo

Synonym: TBFG_12867

Alternate gene names: 148824042

Gene position: 3173699-3172218 (Counterclockwise)

Preceding gene: 148824048

Following gene: 148824041

Centisome position: 71.73

GC content: 63.7

Gene sequence:

>1482_bases
GTGTCAGACCTAGCCAGAACCGACGTCGTGCTGATCGGTGCGGGCATCATGAGCGCCACGCTGGGGGTGCTGCTGCGTCG
GCTCGAACCGAACTGGTCAATCACCCTGATCGAACGGCTGGACGCGGTAGCCGCCGAAAGCAGCGGTCCCTGGAACAACG
CCGGCACCGGGCACTCCGCGCTGTGCGAGATGAACTACACCCCAGAAATGCCGGACGGCTCGATCGACATCACCAAAGCG
GTGCGTGTCAACGAGCAATTCCAGGTCACCCGCCAGTTCTGGGCATACGCGGCCGAAAACGGCATCCTCACCGACGTGCG
CAGCTTCCTCAACCCTGTGCCGCACGTGAGTTTCGTCCATGGATCGCGGGGCGTCGAGTATCTACGGCGCCGCCAAAAGG
CGTTGGCCGGCAACCCGCTGTTCGCCGGCACCGAGTTCATCGAGAGTCCCGACGAATTCGCCCGCCGGCTGCCGTTCATG
GCCGCTAAACGGGCCTTCTCCGAGCCGGTGGCGCTCAACTGGGCCGCCGACGGCACCGACGTCGACTTCGGTGCCCTCGC
CAAACAACTCATCGGCTATTGCGTGCAAAATGGCACTACCGCGTTGTTCGGGCACGAGGTTCGCAACCTCTCGCGGCAAT
CCGACGGCAGCTGGACGGTCACCATGTGCAACCGCCGGACCGGCGAAAAGCGCAAGTTGAACACCAAGTTCGTCTTTGTC
GGGGCCGGGGGTGACACCTTGCCGGTGCTGCAGAAATCCGGGATCAAAGAGGTCAAAGGCTTCGCCGGCTTCCCGATTGG
CGGTCGGTTCCTGCGCGCCGGGAACCCGGCGCTCACCGCCTCGCATCGGGCAAAGGTATATGGCTTCCCGGCGCCGGGCG
CCCCGCCGTTGGGCGCCTTGCATCTGGATCTGCGGTTTGTCAACGGCAAGTCGTGGCTGGTGTTCGGGCCATACGCCGGC
TGGTCGCCGAAGTTCTTGAAACACGGGCAGATCAGCGACCTGCCCCGGTCGATCAGGCCGGACAATCTGTTGTCCGTGCT
CGGCGTGGGCCTCACCGAGCGGAGACTGCTGAACTACTTGATCAGCCAGCTGCGTCTCTCTGAACCCGAGCGGGTCAGTG
CGCTGCGCGAATTCGCCCCTAGCGCAATCGATTCGGACTGGGAGTTGACGATAGCCGGTCAGCGGGTACAGGTGATCCGG
CGAGATGAACGCAACGGCGGGGTGCTCGAGTTCGGCACGACGGTCATCGGCGATGCTGACGGTAGTATTGCCGGACTACT
GGGCGGCTCCCCAGGGGCTTCGACCGCGGTGGCGATCATGCTGGACGTGCTGCAGAAATGCTTTGCCAACCGCTATCAAT
CCTGGCTGCCCACGCTCAAAGAAATGGTGCCGTCGCTGGGGGTGCAGCTGTCGAATGAACCCGCGCTGTTCGACGAGGTG
TGGTCATGGAGCACCAAGGCGCTGAAGTTAGGTGCCGCATGA

Upstream 100 bases:

>100_bases
CGCTGCACAGGGTTACTGGCCCAGGAGGCGGACGTCATCGTGTTAACACCCGTCGGGATAACCTGGGAGCGGCGCAGCCA
AGGAAGGAACCAACCGTCCG

Downstream 100 bases:

>100_bases
CCCGCGCCGGCGACGATACAGTGGGGGTACCGCCCGCTTGCGGGGGAGAGCGGCGCTTATGACCGAAGCACTGCGCCGCG
TCTGGGCCAAAGACCTTGAC

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone]

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MSDLARTDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAAESSGPWNNAGTGHSALCEMNYTPEMPDGSIDITKA
VRVNEQFQVTRQFWAYAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLFAGTEFIESPDEFARRLPFM
AAKRAFSEPVALNWAADGTDVDFGALAKQLIGYCVQNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFV
GAGGDTLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAPPLGALHLDLRFVNGKSWLVFGPYAG
WSPKFLKHGQISDLPRSIRPDNLLSVLGVGLTERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQRVQVIR
RDERNGGVLEFGTTVIGDADGSIAGLLGGSPGASTAVAIMLDVLQKCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEV
WSWSTKALKLGAA

Sequences:

>Translated_493_residues
MSDLARTDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAAESSGPWNNAGTGHSALCEMNYTPEMPDGSIDITKA
VRVNEQFQVTRQFWAYAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLFAGTEFIESPDEFARRLPFM
AAKRAFSEPVALNWAADGTDVDFGALAKQLIGYCVQNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFV
GAGGDTLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAPPLGALHLDLRFVNGKSWLVFGPYAG
WSPKFLKHGQISDLPRSIRPDNLLSVLGVGLTERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQRVQVIR
RDERNGGVLEFGTTVIGDADGSIAGLLGGSPGASTAVAIMLDVLQKCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEV
WSWSTKALKLGAA
>Mature_492_residues
SDLARTDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAAESSGPWNNAGTGHSALCEMNYTPEMPDGSIDITKAV
RVNEQFQVTRQFWAYAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLFAGTEFIESPDEFARRLPFMA
AKRAFSEPVALNWAADGTDVDFGALAKQLIGYCVQNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFVG
AGGDTLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAPPLGALHLDLRFVNGKSWLVFGPYAGW
SPKFLKHGQISDLPRSIRPDNLLSVLGVGLTERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQRVQVIRR
DERNGGVLEFGTTVIGDADGSIAGLLGGSPGASTAVAIMLDVLQKCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEVW
SWSTKALKLGAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=492, Percent_Identity=48.1707317073171, Blast_Score=464, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO_MYCBO (P65420)

Other databases:

- EMBL:   BX248343
- RefSeq:   NP_856522.1
- ProteinModelPortal:   P65420
- EnsemblBacteria:   EBMYCT00000016190
- GeneID:   1092232
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2877c
- GeneTree:   EBGT00050000015585
- HOGENOM:   HBG289663
- OMA:   NALKEYF
- ProtClustDB:   PRK05257
- BioCyc:   MBOV233413:MB2877C-MONOMER
- BRENDA:   1.1.99.16
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 53596; Mature: 53465

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLARTDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAAESSGPWNNAGTGHSA
CCCCHHCCEEEEECHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCE
LCEMNYTPEMPDGSIDITKAVRVNEQFQVTRQFWAYAAENGILTDVRSFLNPVPHVSFVH
EEECCCCCCCCCCCEEEEHEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEE
GSRGVEYLRRRQKALAGNPLFAGTEFIESPDEFARRLPFMAAKRAFSEPVALNWAADGTD
CCCCHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHCCHHHHHHHCCCCEEEEECCCCCC
VDFGALAKQLIGYCVQNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFV
CCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEE
GAGGDTLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAPPLGAL
ECCCCCCHHHHHCCHHHHHCCCCCCCCCEEEECCCCCEECCCCEEEEECCCCCCCCCCEE
HLDLRFVNGKSWLVFGPYAGWSPKFLKHGQISDLPRSIRPDNLLSVLGVGLTERRLLNYL
EEEEEEECCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHH
ISQLRLSEPERVSALREFAPSAIDSDWELTIAGQRVQVIRRDERNGGVLEFGTTVIGDAD
HHHHHCCCCHHHHHHHHHCCHHCCCCCEEEEECCEEEEEEECCCCCCEEEECCEEEECCC
GSIAGLLGGSPGASTAVAIMLDVLQKCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEV
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHH
WSWSTKALKLGAA
HCCCCHHEEECCC
>Mature Secondary Structure 
SDLARTDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAAESSGPWNNAGTGHSA
CCCHHCCEEEEECHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCE
LCEMNYTPEMPDGSIDITKAVRVNEQFQVTRQFWAYAAENGILTDVRSFLNPVPHVSFVH
EEECCCCCCCCCCCEEEEHEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEE
GSRGVEYLRRRQKALAGNPLFAGTEFIESPDEFARRLPFMAAKRAFSEPVALNWAADGTD
CCCCHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHCCHHHHHHHCCCCEEEEECCCCCC
VDFGALAKQLIGYCVQNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFV
CCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEE
GAGGDTLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAPPLGAL
ECCCCCCHHHHHCCHHHHHCCCCCCCCCEEEECCCCCEECCCCEEEEECCCCCCCCCCEE
HLDLRFVNGKSWLVFGPYAGWSPKFLKHGQISDLPRSIRPDNLLSVLGVGLTERRLLNYL
EEEEEEECCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHH
ISQLRLSEPERVSALREFAPSAIDSDWELTIAGQRVQVIRRDERNGGVLEFGTTVIGDAD
HHHHHCCCCHHHHHHHHHCCHHCCCCCEEEEECCEEEEEEECCCCCCEEEECCEEEECCC
GSIAGLLGGSPGASTAVAIMLDVLQKCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEV
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHH
WSWSTKALKLGAA
HCCCCHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972