| Definition | Mycobacterium tuberculosis F11, complete genome. |
|---|---|
| Accession | NC_009565 |
| Length | 4,424,435 |
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The map label for this gene is ftsK [H]
Identifier: 148823937
GI number: 148823937
Start: 3071810
End: 3074461
Strand: Reverse
Name: ftsK [H]
Synonym: TBFG_12761
Alternate gene names: 148823937
Gene position: 3074461-3071810 (Counterclockwise)
Preceding gene: 148823940
Following gene: 148823934
Centisome position: 69.49
GC content: 67.68
Gene sequence:
>2652_bases ATGCTGGGGCCTCCTGGAACTCCGCGCGTCGGGCGGCGTGACGCGGCACGATCACTTGTCACCCTACTCAGGAGACCCTG GCAACGAGGCGAGCAGATCGCCGTTACCAGTGTGGCGGATGGTGTAGATGGTGTGATAGCGACTAGGCTTGCCGTTATGT CTAGCAAGACCGTTGCCCGCTCCGGCACTCGAACGAGCAGGTCAAAGGCCACTTCGCGGGGCGCGTCCCGAAGTGCGCGA TCGGCCGTGCCCAGAAAGAGGTCGAGGCCCGTCAAAGGGGTCGGCAGACCCTCCCGACGGCACCATCGGTCGCTGCTGGT GTCTACCGGACTCGCCTGCGGCCGGGCCATGCGTGCCGTCTGGATGATGGCGGCCAAGGGCACCGGCGGCGCGGCGCGGT CGATCGGGCGAGCCCGCGACATCGAGCCCGGGCATCGCCGCGACGGAATCGCGCTGGTGCTGCTCGGCCTTGCCGTGGTA GTCGCCGCGAGCTCGTGGTTCGACGCCGCCCGGCCGCTCGGCGCGTGGGTCGACGCCTTGTTGCGGACGTTCATCGGGTC GGCAGTGGTCATGCTCCCGCTGGTTGCCGCCGCCGTGGCCGTGGTGCTGATGCGTACGTCGCCCAACCCCGATTCGCGGC CGCGGCTGATCCTCGGCGCCAGCCTGATCGGCTTGTCGTTTCTCGGCTTGTGCCACCTGTGGGCGGGCTCACCCGAGGCC CCGGAGTCGCGTTTGCGCGCCGCGGGGTTCATCGGTTTCGCGATCGGCGGGCCGCTCTCGGACGGGTTGACCGCCTGGAT CGCCGCGCCGCTGTTATTCATCGGCGCGCTGTTCGGATTGCTCCTGCTGGCCGGGATCACGATCCGAGAGGTGCCAGATG CCATGCGCGCCATGTTCGGCACCCGGCTGTTGCCACGGGAATACGCCGACGACTTCGAGGACTTCGCGGACTTCGATGGT GACGACGCGGACACCGTCGAAGTCGCCCGCCAGGACTTCTCCGACGGTTACTACGACGAGGTGCCCCTGTGCTCCGACGA CGGGCCACCGGCCTGGCCGTCGGCCGAGGTTCCGCAGGATGACACTGCGACGATACCGGAAGCCTCCGCCGGTCGGGGCT CCGGAAGACGCGGCCGCCGCAAAGATACCCAAGTGCTGGACCGGATCGTCGAGGGTCCCTACACGCTGCCGTCGCTGGAC CTGCTGATATCCGGTGATCCGCCCAAGAAACGCAGTGCGGCCAACACCCACATGGCCGGCGCCATCGGTGAGGTGCTGAC CCAGTTCAAGGTCGACGCGGCCGTCACGGGCTGCACCCGCGGGCCCACCGTCACCCGCTACGAGGTCGAACTGGGGCCCG GCGTCAAGGTCGAGAAGATCACCGCGCTGCAGCGCAACATCGCCTACGCGGTGGCTACCGAGAGCGTGCGCATGCTGGCA CCGATCCCCGGCAAGTCCGCCGTCGGCATCGAGGTACCCAACACCGACCGGGAAATGGTGCGGTTGGCCGACGTGCTCAC CGCACGAGAGACCCGTCGCGACCATCATCCGTTGGTGATCGGGCTGGGCAAGGACATCGAAGGCGACTTCATCTCGGCCA ACCTGGCCAAGATGCCGCACCTGCTGGTGGCCGGCTCGACGGGCTCGGGAAAGTCCAGCTTCGTCAACTCCATGCTGGTG TCGCTGTTGACCCGGGCCACCCCGGAAGAGGTCAGGATGATCCTGATCGACCCGAAGATGGTGGAACTGACGCCGTATGA AGGCATTCCGCATCTGATCACGCCGATCATCACCCAGCCGAAGAAGGCCGCGGCCGCGCTGGCCTGGCTGGTCGACGAGA TGGAGCAGCGCTACCAGGACATGCAGGCCTCCCGGGTGCGCCACATCGACGACTTCAACGACAAGGTGCGATCCGGGGCC ATCACCGCGCCGCTGGGCAGCCAGCGCGAGTATCGGCCCTACCCCTACGTGGTGGCCATCGTCGACGAGTTGGCCGACCT CATGATGACCGCGCCGCGTGACGTCGAGGACGCCATCGTGCGGATCACCCAGAAAGCCCGCGCCGCCGGCATCCACCTGG TGCTGGCCACCCAGCGCCCGTCGGTGGACGTGGTCACCGGGCTGATCAAGACCAACGTGCCGTCGCGGCTGGCGTTTGCC ACCTCGTCGCTGACCGACAGCCGGGTGATCCTGGACCAGGCGGGCGCGGAAAAGCTGATCGGCATGGGCGACGGCCTGTT CTTGCCGATGGGTGCGAGCAAACCCCTCCGGCTGCAGGGCGCTTACGTCTCCGACGAAGAGATCCACGCCGTCGTCACCG CCTGCAAGGAACAGGCCGAACCCGAATACACCGAGGGCGTCACCACGGCTAAACCCACCGCGGAGCGCACCGACGTCGAC CCCGACATCGGCGACGACATGGACGTCTTCCTGCAGGCCGTGGAACTGGTGGTGTCCAGCCAGTTCGGGTCGACGTCGAT GCTGCAGCGCAAGCTGCGGGTCGGCTTCGCCAAAGCGGGCCGTTTGATGGACCTGATGGAGACCCGCGGCATCGTCGGGC CCAGCGAAGGCTCGAAGGCCCGTGAGGTGCTGGTCAAGCCCGACGAGTTGGCGGGCACACTGGCCGCGATCCGGGGTGAC GGCGGCGAGTAG
Upstream 100 bases:
>100_bases GGGTTCGCGGTGCACGTCATCGACCGCGCGGGTGAGGATGTCGCGGACGGTGTCGACCGATTCAGGCTTGGCGGTCAGCG TGGCGACGACGACGACGGGC
Downstream 100 bases:
>100_bases CCCGCCGAGCAGACGCAAAATCGCCCATTTCGTGCCGAAATGAGGCGATTTTGCGTCTGCTCGCCGGGCTACAGCACCAG CAGCATCCGGGAGTTGCCGA
Product: cell division transmembrane protein ftsK
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 883; Mature: 883
Protein sequence:
>883_residues MLGPPGTPRVGRRDAARSLVTLLRRPWQRGEQIAVTSVADGVDGVIATRLAVMSSKTVARSGTRTSRSKATSRGASRSAR SAVPRKRSRPVKGVGRPSRRHHRSLLVSTGLACGRAMRAVWMMAAKGTGGAARSIGRARDIEPGHRRDGIALVLLGLAVV VAASSWFDAARPLGAWVDALLRTFIGSAVVMLPLVAAAVAVVLMRTSPNPDSRPRLILGASLIGLSFLGLCHLWAGSPEA PESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLAGITIREVPDAMRAMFGTRLLPREYADDFEDFADFDG DDADTVEVARQDFSDGYYDEVPLCSDDGPPAWPSAEVPQDDTATIPEASAGRGSGRRGRRKDTQVLDRIVEGPYTLPSLD LLISGDPPKKRSAANTHMAGAIGEVLTQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLA PIPGKSAVGIEVPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLAKMPHLLVAGSTGSGKSSFVNSMLV SLLTRATPEEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVDEMEQRYQDMQASRVRHIDDFNDKVRSGA ITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFA TSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAVVTACKEQAEPEYTEGVTTAKPTAERTDVD PDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGD GGE
Sequences:
>Translated_883_residues MLGPPGTPRVGRRDAARSLVTLLRRPWQRGEQIAVTSVADGVDGVIATRLAVMSSKTVARSGTRTSRSKATSRGASRSAR SAVPRKRSRPVKGVGRPSRRHHRSLLVSTGLACGRAMRAVWMMAAKGTGGAARSIGRARDIEPGHRRDGIALVLLGLAVV VAASSWFDAARPLGAWVDALLRTFIGSAVVMLPLVAAAVAVVLMRTSPNPDSRPRLILGASLIGLSFLGLCHLWAGSPEA PESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLAGITIREVPDAMRAMFGTRLLPREYADDFEDFADFDG DDADTVEVARQDFSDGYYDEVPLCSDDGPPAWPSAEVPQDDTATIPEASAGRGSGRRGRRKDTQVLDRIVEGPYTLPSLD LLISGDPPKKRSAANTHMAGAIGEVLTQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLA PIPGKSAVGIEVPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLAKMPHLLVAGSTGSGKSSFVNSMLV SLLTRATPEEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVDEMEQRYQDMQASRVRHIDDFNDKVRSGA ITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFA TSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAVVTACKEQAEPEYTEGVTTAKPTAERTDVD PDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGD GGE >Mature_883_residues MLGPPGTPRVGRRDAARSLVTLLRRPWQRGEQIAVTSVADGVDGVIATRLAVMSSKTVARSGTRTSRSKATSRGASRSAR SAVPRKRSRPVKGVGRPSRRHHRSLLVSTGLACGRAMRAVWMMAAKGTGGAARSIGRARDIEPGHRRDGIALVLLGLAVV VAASSWFDAARPLGAWVDALLRTFIGSAVVMLPLVAAAVAVVLMRTSPNPDSRPRLILGASLIGLSFLGLCHLWAGSPEA PESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLAGITIREVPDAMRAMFGTRLLPREYADDFEDFADFDG DDADTVEVARQDFSDGYYDEVPLCSDDGPPAWPSAEVPQDDTATIPEASAGRGSGRRGRRKDTQVLDRIVEGPYTLPSLD LLISGDPPKKRSAANTHMAGAIGEVLTQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLA PIPGKSAVGIEVPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLAKMPHLLVAGSTGSGKSSFVNSMLV SLLTRATPEEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVDEMEQRYQDMQASRVRHIDDFNDKVRSGA ITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFA TSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAVVTACKEQAEPEYTEGVTTAKPTAERTDVD PDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGD GGE
Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind
COG id: COG1674
COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 FtsK domain [H]
Homologues:
Organism=Escherichia coli, GI1787117, Length=490, Percent_Identity=46.9387755102041, Blast_Score=417, Evalue=1e-117,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR018541 - InterPro: IPR002543 [H]
Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]
EC number: NA
Molecular weight: Translated: 94408; Mature: 94408
Theoretical pI: Translated: 8.64; Mature: 8.64
Prosite motif: PS50901 FTSK
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLGPPGTPRVGRRDAARSLVTLLRRPWQRGEQIAVTSVADGVDGVIATRLAVMSSKTVAR CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHH SGTRTSRSKATSRGASRSARSAVPRKRSRPVKGVGRPSRRHHRSLLVSTGLACGRAMRAV CCCCCHHHHHHHCCCCHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH WMMAAKGTGGAARSIGRARDIEPGHRRDGIALVLLGLAVVVAASSWFDAARPLGAWVDAL HHHHCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LRTFIGSAVVMLPLVAAAVAVVLMRTSPNPDSRPRLILGASLIGLSFLGLCHLWAGSPEA HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCC PESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLAGITIREVPDAMRAMFG CHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC TRLLPREYADDFEDFADFDGDDADTVEVARQDFSDGYYDEVPLCSDDGPPAWPSAEVPQD CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC DTATIPEASAGRGSGRRGRRKDTQVLDRIVEGPYTLPSLDLLISGDPPKKRSAANTHMAG CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHH AIGEVLTQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLA HHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEECCCCCEEE PIPGKSAVGIEVPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLAKMPH CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEECCHHHHCCE LLVAGSTGSGKSSFVNSMLVSLLTRATPEEVRMILIDPKMVELTPYEGIPHLITPIITQP EEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCCCHHHHHHHHCCC KKAAAALAWLVDEMEQRYQDMQASRVRHIDDFNDKVRSGAITAPLGSQREYRPYPYVVAI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHH VDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFA HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHH TSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAVVTACKEQAE HHCCCCCCHHHHHCCCHHHHCCCCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHCC PEYTEGVTTAKPTAERTDVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAG CCHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH RLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGDGGE HHHHHHHHCCCCCCCCCCHHHHEECCCHHHHHHHHHHCCCCCC >Mature Secondary Structure MLGPPGTPRVGRRDAARSLVTLLRRPWQRGEQIAVTSVADGVDGVIATRLAVMSSKTVAR CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHH SGTRTSRSKATSRGASRSARSAVPRKRSRPVKGVGRPSRRHHRSLLVSTGLACGRAMRAV CCCCCHHHHHHHCCCCHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH WMMAAKGTGGAARSIGRARDIEPGHRRDGIALVLLGLAVVVAASSWFDAARPLGAWVDAL HHHHCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH LRTFIGSAVVMLPLVAAAVAVVLMRTSPNPDSRPRLILGASLIGLSFLGLCHLWAGSPEA HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCC PESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLAGITIREVPDAMRAMFG CHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC TRLLPREYADDFEDFADFDGDDADTVEVARQDFSDGYYDEVPLCSDDGPPAWPSAEVPQD CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC DTATIPEASAGRGSGRRGRRKDTQVLDRIVEGPYTLPSLDLLISGDPPKKRSAANTHMAG CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHH AIGEVLTQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLA HHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHEEECCCCCEEE PIPGKSAVGIEVPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLAKMPH CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEECCHHHHCCE LLVAGSTGSGKSSFVNSMLVSLLTRATPEEVRMILIDPKMVELTPYEGIPHLITPIITQP EEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEECCCCCCHHHHHHHHCCC KKAAAALAWLVDEMEQRYQDMQASRVRHIDDFNDKVRSGAITAPLGSQREYRPYPYVVAI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHH VDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFA HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHH TSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAVVTACKEQAE HHCCCCCCHHHHHCCCHHHHCCCCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHCC PEYTEGVTTAKPTAERTDVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAG CCHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH RLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGDGGE HHHHHHHHCCCCCCCCCCHHHHEECCCHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]