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The map label for this gene is yqjQ [H]

Identifier: 148823706

GI number: 148823706

Start: 2837996

End: 2838802

Strand: Direct

Name: yqjQ [H]

Synonym: TBFG_12531

Alternate gene names: 148823706

Gene position: 2837996-2838802 (Clockwise)

Preceding gene: 148823704

Following gene: 148823708

Centisome position: 64.14

GC content: 65.8

Gene sequence:

>807_bases
ATGCCGATACCCGCGCCCAGCCCCGACGCACGTGCCGTTGTCACCGGGGCTTCGCAGAACATCGGCGCGGCGCTGGCCAC
CGAACTGGCCGCACGCGGGCACCACCTGATCGTCACCGCACGACGCGAGGACGTGTTGACCGAGTTGGCTGCCCGGCTGG
CCGACAAGTACCGCGTCACGGTCGACGTGCGACCGGCCGATCTGGCCGATCCGCAAGAACGATCGAAACTGGCCGACGAG
CTGGCTGCCCGGCCCATCTCGATCCTGTGCGCCAACGCGGGTACCGCGACATTCGGCCCGATCGCATCGCTCGATCTTGC
CGGCGAAAAGACGCAGGTGCAGTTGAATGCCGTGGCGGTGCACGACCTTACGTTGGCGGTGTTGCCGGGCATGATCGAGC
GCAAGGCCGGCGGCATCTTGATTTCTGGTTCGGCGGCCGGCAATTCACCGATTCCCTACAACGCCACCTATGCCGCGACC
AAGGCCTTCGTGAACACCTTCAGCGAATCTCTGCGCGGTGAGCTACGCGGCTCCGGCGTGCACGTCACGGTGCTGGCCCC
GGGCCCGGTTCGCACCGAGCTACCGGATGCCTCCGAAGCGTCACTGGTCGAGAAGCTGGTGCCGGACTTCCTGTGGATCT
CGACGGAGCACACCGCCCGGGTATCGCTGAATGCCTTGGAGCGCAACAAGATGCGCGTCGTTCCGGGTCTGACGTCAAAG
GCGATGTCGGTGGCCAGCCAATACGCTCCGCGCGCCATCGTGGCGCCAATCGTGGGTGCCTTTTACAAGAGGCTTGGGGG
CAGCTAG

Upstream 100 bases:

>100_bases
ACCCCGGGTTATTCATGTCCGGCACTTTATTGCTTTTGGCAGCGACCCGCTGCGCCCGGCTCCGCCGCGCTCGCGATCGC
TACGTGTCTACGATTGGCGC

Downstream 100 bases:

>100_bases
GCATCACTTCCGGCGGCGGCGCCCGGTGCCGAAGATGCTGCGGGTGATCTCGCGTGCGGTGGTGTTGAGGACGCTCTTGA
CGGTCGGATTCTTGAGTATC

Product: short-chain type dehydrogenase/reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MPIPAPSPDARAVVTGASQNIGAALATELAARGHHLIVTARREDVLTELAARLADKYRVTVDVRPADLADPQERSKLADE
LAARPISILCANAGTATFGPIASLDLAGEKTQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAAT
KAFVNTFSESLRGELRGSGVHVTVLAPGPVRTELPDASEASLVEKLVPDFLWISTEHTARVSLNALERNKMRVVPGLTSK
AMSVASQYAPRAIVAPIVGAFYKRLGGS

Sequences:

>Translated_268_residues
MPIPAPSPDARAVVTGASQNIGAALATELAARGHHLIVTARREDVLTELAARLADKYRVTVDVRPADLADPQERSKLADE
LAARPISILCANAGTATFGPIASLDLAGEKTQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAAT
KAFVNTFSESLRGELRGSGVHVTVLAPGPVRTELPDASEASLVEKLVPDFLWISTEHTARVSLNALERNKMRVVPGLTSK
AMSVASQYAPRAIVAPIVGAFYKRLGGS
>Mature_267_residues
PIPAPSPDARAVVTGASQNIGAALATELAARGHHLIVTARREDVLTELAARLADKYRVTVDVRPADLADPQERSKLADEL
AARPISILCANAGTATFGPIASLDLAGEKTQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAATK
AFVNTFSESLRGELRGSGVHVTVLAPGPVRTELPDASEASLVEKLVPDFLWISTEHTARVSLNALERNKMRVVPGLTSKA
MSVASQYAPRAIVAPIVGAFYKRLGGS

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=202, Percent_Identity=33.6633663366337, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI226371731, Length=190, Percent_Identity=34.7368421052632, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4557649, Length=202, Percent_Identity=29.2079207920792, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI7706318, Length=207, Percent_Identity=31.8840579710145, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI40548397, Length=235, Percent_Identity=26.3829787234043, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI214010158, Length=235, Percent_Identity=26.3829787234043, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI214010156, Length=235, Percent_Identity=26.3829787234043, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI22758144, Length=235, Percent_Identity=26.3829787234043, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI7657478, Length=185, Percent_Identity=28.6486486486486, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI223718074, Length=187, Percent_Identity=28.3422459893048, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI109715829, Length=195, Percent_Identity=31.2820512820513, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI32455239, Length=201, Percent_Identity=27.8606965174129, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI5031765, Length=201, Percent_Identity=27.8606965174129, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4503817, Length=194, Percent_Identity=29.3814432989691, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787820, Length=237, Percent_Identity=32.9113924050633, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1786701, Length=200, Percent_Identity=30, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082100, Length=191, Percent_Identity=34.5549738219895, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787335, Length=188, Percent_Identity=31.3829787234043, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI212646214, Length=210, Percent_Identity=30, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25152911, Length=206, Percent_Identity=32.0388349514563, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560176, Length=191, Percent_Identity=29.8429319371728, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559552, Length=225, Percent_Identity=28, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17557668, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17570069, Length=184, Percent_Identity=26.6304347826087, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319635, Length=209, Percent_Identity=29.1866028708134, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=33.8541666666667, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=195, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640442, Length=197, Percent_Identity=34.010152284264, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=35.2941176470588, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24584744, Length=187, Percent_Identity=35.2941176470588, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=34.8958333333333, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=34.8958333333333, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24584752, Length=192, Percent_Identity=34.8958333333333, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=30.1587301587302, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=30.2564102564103, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24580925, Length=191, Percent_Identity=30.8900523560209, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007236, Length=195, Percent_Identity=29.7435897435897, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355631, Length=198, Percent_Identity=32.3232323232323, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28013; Mature: 27882

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIPAPSPDARAVVTGASQNIGAALATELAARGHHLIVTARREDVLTELAARLADKYRVT
CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCEEEE
VDVRPADLADPQERSKLADELAARPISILCANAGTATFGPIASLDLAGEKTQVQLNAVAV
EEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCEEEEEEEEEE
HDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAATKAFVNTFSESLRGELRGSGV
HHHHHHHHCHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
HVTVLAPGPVRTELPDASEASLVEKLVPDFLWISTEHTARVSLNALERNKMRVVPGLTSK
EEEEECCCCCCCCCCCCHHHHHHHHHCCHHEEEECCCCEEEEEEHHCCCCEEECCCCHHH
AMSVASQYAPRAIVAPIVGAFYKRLGGS
HHHHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PIPAPSPDARAVVTGASQNIGAALATELAARGHHLIVTARREDVLTELAARLADKYRVT
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCEEEE
VDVRPADLADPQERSKLADELAARPISILCANAGTATFGPIASLDLAGEKTQVQLNAVAV
EEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCEEEEEEEEEE
HDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAATKAFVNTFSESLRGELRGSGV
HHHHHHHHCHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
HVTVLAPGPVRTELPDASEASLVEKLVPDFLWISTEHTARVSLNALERNKMRVVPGLTSK
EEEEECCCCCCCCCCCCHHHHHHHHHCCHHEEEECCCCEEEEEEHHCCCCEEECCCCHHH
AMSVASQYAPRAIVAPIVGAFYKRLGGS
HHHHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]