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The map label for this gene is orn

Identifier: 148823708

GI number: 148823708

Start: 2840475

End: 2841122

Strand: Direct

Name: orn

Synonym: TBFG_12533

Alternate gene names: 148823708

Gene position: 2840475-2841122 (Clockwise)

Preceding gene: 148823706

Following gene: 148823710

Centisome position: 64.2

GC content: 65.43

Gene sequence:

>648_bases
GTGCAAGACGAACTGGTGTGGATCGACTGCGAGATGACCGGGCTCGATCTGGGTTCGGACAAGCTGATCGAGATAGCCGC
CCTGGTCACCGATGCCGATCTGAACATTCTCGGCGACGGGGTGGACGTGGTGATGCACGCCGACGACGCCGCGCTGTCGG
GCATGATCGACGTGGTCGCCGAGATGCACTCGCGGTCGGGGCTGATCGACGAGGTGAAGGCATCCACGGTCGACCTAGCG
ACCGCCGAGGCCATGGTGCTCGACTACATCAACGAGCACGTCAAGCAGCCCAAGACCGCCCCACTGGCCGGCAACTCGAT
CGCCACCGACCGCGCGTTCATCGCCCGCGACATGCCCACGCTGGACTCGTTTCTGCACTACCGAATGATCGACGTCAGCT
CGATCAAGGAACTGTGCCGGCGCTGGTATCCGCGGATCTACTTCGGCCAGCCGCCCAAGGGGCTGACGCACCGGGCGCTG
GCCGACATCCACGAATCCATCCGCGAACTGCGGTTCTACCGCCGCACCGCGTTCGTGCCCCAGCCCGGCCCTTCTACCAG
CGAAATCGCGGCCGTCGTCGCCGAGCTTTCCGACGGGGCGGGCGCGCAGGAAGAAACAGATTCGGCCGAGGCGCCCCAGA
GCGGTTAA

Upstream 100 bases:

>100_bases
GCCAGGTCCACCGGCCGCCGATTCGGTGCCCATAGCTGGATCACACTACTTGCCCGGGGGAGACAGCCGCGACGGCTCGC
ATGCGCCTACGCTGAGCGCT

Downstream 100 bases:

>100_bases
TATCGACGTCGCCGCTCATTAGCCCCCGCGGGGGCGGCCGGCGGCCATGGTGAGTGTAGTTCAGTTGGTAGAGCACCAGG
TTGTGATCCTGGGTGTCGCG

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MQDELVWIDCEMTGLDLGSDKLIEIAALVTDADLNILGDGVDVVMHADDAALSGMIDVVAEMHSRSGLIDEVKASTVDLA
TAEAMVLDYINEHVKQPKTAPLAGNSIATDRAFIARDMPTLDSFLHYRMIDVSSIKELCRRWYPRIYFGQPPKGLTHRAL
ADIHESIRELRFYRRTAFVPQPGPSTSEIAAVVAELSDGAGAQEETDSAEAPQSG

Sequences:

>Translated_215_residues
MQDELVWIDCEMTGLDLGSDKLIEIAALVTDADLNILGDGVDVVMHADDAALSGMIDVVAEMHSRSGLIDEVKASTVDLA
TAEAMVLDYINEHVKQPKTAPLAGNSIATDRAFIARDMPTLDSFLHYRMIDVSSIKELCRRWYPRIYFGQPPKGLTHRAL
ADIHESIRELRFYRRTAFVPQPGPSTSEIAAVVAELSDGAGAQEETDSAEAPQSG
>Mature_215_residues
MQDELVWIDCEMTGLDLGSDKLIEIAALVTDADLNILGDGVDVVMHADDAALSGMIDVVAEMHSRSGLIDEVKASTVDLA
TAEAMVLDYINEHVKQPKTAPLAGNSIATDRAFIARDMPTLDSFLHYRMIDVSSIKELCRRWYPRIYFGQPPKGLTHRAL
ADIHESIRELRFYRRTAFVPQPGPSTSEIAAVVAELSDGAGAQEETDSAEAPQSG

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=178, Percent_Identity=48.314606741573, Blast_Score=182, Evalue=3e-46,
Organism=Escherichia coli, GI87082382, Length=173, Percent_Identity=47.3988439306358, Blast_Score=161, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17557752, Length=185, Percent_Identity=44.8648648648649, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6323088, Length=183, Percent_Identity=39.344262295082, Blast_Score=125, Evalue=4e-30,
Organism=Drosophila melanogaster, GI21355135, Length=176, Percent_Identity=45.4545454545455, Blast_Score=166, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_MYCBO (P65598)

Other databases:

- EMBL:   BX248342
- RefSeq:   NP_856184.1
- ProteinModelPortal:   P65598
- SMR:   P65598
- EnsemblBacteria:   EBMYCT00000016443
- GeneID:   1090865
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2539
- GeneTree:   EBGT00050000017547
- HOGENOM:   HBG448545
- OMA:   ARRWYPR
- ProtClustDB:   PRK05359
- BioCyc:   MBOV233413:MB2539-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 23443; Mature: 23443

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: ACT_SITE 127-127

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDELVWIDCEMTGLDLGSDKLIEIAALVTDADLNILGDGVDVVMHADDAALSGMIDVVA
CCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCEEEEEECCHHHHHHHHHHHH
EMHSRSGLIDEVKASTVDLATAEAMVLDYINEHVKQPKTAPLAGNSIATDRAFIARDMPT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCHH
LDSFLHYRMIDVSSIKELCRRWYPRIYFGQPPKGLTHRALADIHESIRELRFYRRTAFVP
HHHHHHHHHCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
QPGPSTSEIAAVVAELSDGAGAQEETDSAEAPQSG
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQDELVWIDCEMTGLDLGSDKLIEIAALVTDADLNILGDGVDVVMHADDAALSGMIDVVA
CCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCEEEEEECCHHHHHHHHHHHH
EMHSRSGLIDEVKASTVDLATAEAMVLDYINEHVKQPKTAPLAGNSIATDRAFIARDMPT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCHH
LDSFLHYRMIDVSSIKELCRRWYPRIYFGQPPKGLTHRALADIHESIRELRFYRRTAFVP
HHHHHHHHHCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
QPGPSTSEIAAVVAELSDGAGAQEETDSAEAPQSG
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972