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The map label for this gene is ppe40

Identifier: 148823559

GI number: 148823559

Start: 2650983

End: 2652830

Strand: Reverse

Name: ppe40

Synonym: TBFG_12382

Alternate gene names: 148823559

Gene position: 2652830-2650983 (Counterclockwise)

Preceding gene: 148823560

Following gene: 148823556

Centisome position: 59.96

GC content: 61.63

Gene sequence:

>1848_bases
GTGGTGAATTTTTCGGTGTTGCCGCCGGAGATTAATTCGGGGCGGATGTTTTTTGGTGCGGGGTCGGGGCCGATGTTGGC
GGCGGCGGCGGCCTGGGATGGGTTGGCGGCTGAGTTGGGGTTGGCGGCGGAGTCGTTTGGGTTGGTGACCTCGGGTCTGG
CGGGTGGGTCGGGTCAGGCGTGGCAGGGTGCGGCGGCGGCGGCGATGGTGGTGGCGGCGGCGCCGTATGCGGGGTGGTTG
GCTGCTGCGGCGGCGCGGGCTGGGGGGGCTGCGGTTCAGGCTAAGGCGGTGGCCGGCGCGTTTGAGGCGGCGCGGGCGGC
CATGGTGGATCCGGTGGTGGTGGCGGCTAATCGCAGTGCGTTTGTGCAGTTGGTGCTGTCGAATGTGTTTGGGCAGAATG
CGCCGGCGATTGCCGCTGCTGAGGCCACCTATGAGCAGATGTGGGCTGCCGATGTGGCGGCGATGGTGGGTTATCACGGT
GGGGCATCGGCGGCGGCGGCGGCGTTGGCGCCATGGCAGCAGGCGGTGCCGGGCTTGTCGGGCTTGCTAGGCGGTGCGGC
TAACGCACCGGCGGCCGCTGCACAAGGCGCTGCACAAGGCCTCGCCGAGCTGACCTTGAATTTGGGTGTCGGCAACATCG
GCAGCCTCAACCTGGGCAGCGGCAACATCGGCGGTACCAACGTGGGCAGTGGCAATGTCGGCGGCACCAACCTGGGCAGC
GGGAACTACGGCAGCCTGAACTGGGGCAGCGGAAACACCGGTACCGGCAATGCCGGCAGCGGAAACACGGGTGACTACAA
CCCTGGCAGCGGAAACTTCGGCAGCGGAAACTTCGGCAGCGGAAATATCGGCAGCCTCAATGTGGGCAGCGGAAACTTCG
GCACGCTCAACCTCGCCAACGGAAATAACGGTGATGTCAATTTCGGCGGCGGGAACACCGGCGACTTCAACTTTGGCGGC
GGGAATAATGGCACCCTCAACTTTGGGTTCGGAAACACCGGCAGCGGGAATTTCGGTTTCGGAAACACGGGCAACAACAA
TATCGGTATCGGGCTCACCGGTGATGGTCAGATCGGCATCGGCGGACTGAACTCAGGCACTGGAAACATCGGCTTCGGAA
ACTCCGGCAACAACAACATCGGCTTCTTCAACTCGGGTGATGGAAACATCGGCTTCTTCAACTCGGGTGACGGCAACACG
GGTTTCGGGAACGCCGGAAATATCAACACCGGTTTCTGGAACGCAGGCAATTTAAACACGGGCTTCGGGAGTGCCGGCAA
CGGAAACGTCGGTATCTTCGACGGCGGGAACTCAAACTCGGGCAGCTTCAACGTGGGCTTTCAGAACACCGGCTTCGGAA
ATTCGGGTGCTGGAAACACCGGCTTCTTCAATGCGGGTGACTCGAACACCGGTTTCGCGAACGCAGGTAACGTCAACACC
GGTTTCTTTAACGGTGGAGATATCAACACCGGTGGTTTCAATGGCGGCAACGTCAACACCGGTTTTGGCAGCGCGCTCAC
CCAAGCAGGTGCCAACTCGGGCTTCGGGAACCTCGGTACCGGCAACTCGGGTTGGGGGAACAGTGACCCCTCGGGCACCG
GCAACTCCGGGTTCTTCAACACAGGCAACGGTAATTCGGGCTTCTCCAACGCCGGCCCAGCCATGCTTCCTGGCTTCAAC
TCCGGGTTTGCAAACATTGGCTCTTTCAATGCAGGAATTGCAAACTCGGGTAACAACCTCGCCGGTATCTCCAACTCGGG
TGACGACAGTTCGGGTGCGGTAAATTCGGGTAGCCAGAACTCCGGTGCTTTCAATGCGGGTGTAGGACTTTCGGGATTCT
TCAGGTAG

Upstream 100 bases:

>100_bases
GCCGCTGGGTGGGCGGCGCCGTGGTGACGGGTGTCCGCGTGTCGTTTGGGGTAACGCGCGGGGGTGCGGTTGAGAATGAT
TTGTTAGAGGAGGGGCGGTA

Downstream 100 bases:

>100_bases
TCGGCACTTGCCACGGCCCGGTTGGGTGTGCCCGGGTGACCCGTGCGGCCACGGTTCTTCCTGGTCGACGCGTCTCTGGC
TCACCTTCAGATGCCGGTAG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MVNFSVLPPEINSGRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAGGSGQAWQGAAAAAMVVAAAPYAGWL
AAAAARAGGAAVQAKAVAGAFEAARAAMVDPVVVAANRSAFVQLVLSNVFGQNAPAIAAAEATYEQMWAADVAAMVGYHG
GASAAAAALAPWQQAVPGLSGLLGGAANAPAAAAQGAAQGLAELTLNLGVGNIGSLNLGSGNIGGTNVGSGNVGGTNLGS
GNYGSLNWGSGNTGTGNAGSGNTGDYNPGSGNFGSGNFGSGNIGSLNVGSGNFGTLNLANGNNGDVNFGGGNTGDFNFGG
GNNGTLNFGFGNTGSGNFGFGNTGNNNIGIGLTGDGQIGIGGLNSGTGNIGFGNSGNNNIGFFNSGDGNIGFFNSGDGNT
GFGNAGNINTGFWNAGNLNTGFGSAGNGNVGIFDGGNSNSGSFNVGFQNTGFGNSGAGNTGFFNAGDSNTGFANAGNVNT
GFFNGGDINTGGFNGGNVNTGFGSALTQAGANSGFGNLGTGNSGWGNSDPSGTGNSGFFNTGNGNSGFSNAGPAMLPGFN
SGFANIGSFNAGIANSGNNLAGISNSGDDSSGAVNSGSQNSGAFNAGVGLSGFFR

Sequences:

>Translated_615_residues
MVNFSVLPPEINSGRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAGGSGQAWQGAAAAAMVVAAAPYAGWL
AAAAARAGGAAVQAKAVAGAFEAARAAMVDPVVVAANRSAFVQLVLSNVFGQNAPAIAAAEATYEQMWAADVAAMVGYHG
GASAAAAALAPWQQAVPGLSGLLGGAANAPAAAAQGAAQGLAELTLNLGVGNIGSLNLGSGNIGGTNVGSGNVGGTNLGS
GNYGSLNWGSGNTGTGNAGSGNTGDYNPGSGNFGSGNFGSGNIGSLNVGSGNFGTLNLANGNNGDVNFGGGNTGDFNFGG
GNNGTLNFGFGNTGSGNFGFGNTGNNNIGIGLTGDGQIGIGGLNSGTGNIGFGNSGNNNIGFFNSGDGNIGFFNSGDGNT
GFGNAGNINTGFWNAGNLNTGFGSAGNGNVGIFDGGNSNSGSFNVGFQNTGFGNSGAGNTGFFNAGDSNTGFANAGNVNT
GFFNGGDINTGGFNGGNVNTGFGSALTQAGANSGFGNLGTGNSGWGNSDPSGTGNSGFFNTGNGNSGFSNAGPAMLPGFN
SGFANIGSFNAGIANSGNNLAGISNSGDDSSGAVNSGSQNSGAFNAGVGLSGFFR
>Mature_615_residues
MVNFSVLPPEINSGRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAGGSGQAWQGAAAAAMVVAAAPYAGWL
AAAAARAGGAAVQAKAVAGAFEAARAAMVDPVVVAANRSAFVQLVLSNVFGQNAPAIAAAEATYEQMWAADVAAMVGYHG
GASAAAAALAPWQQAVPGLSGLLGGAANAPAAAAQGAAQGLAELTLNLGVGNIGSLNLGSGNIGGTNVGSGNVGGTNLGS
GNYGSLNWGSGNTGTGNAGSGNTGDYNPGSGNFGSGNFGSGNIGSLNVGSGNFGTLNLANGNNGDVNFGGGNTGDFNFGG
GNNGTLNFGFGNTGSGNFGFGNTGNNNIGIGLTGDGQIGIGGLNSGTGNIGFGNSGNNNIGFFNSGDGNIGFFNSGDGNT
GFGNAGNINTGFWNAGNLNTGFGSAGNGNVGIFDGGNSNSGSFNVGFQNTGFGNSGAGNTGFFNAGDSNTGFANAGNVNT
GFFNGGDINTGGFNGGNVNTGFGSALTQAGANSGFGNLGTGNSGWGNSDPSGTGNSGFFNTGNGNSGFSNAGPAMLPGFN
SGFANIGSFNAGIANSGNNLAGISNSGDDSSGAVNSGSQNSGAFNAGVGLSGFFR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE40_MYCTU (Q7D7A1)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   E70663
- RefSeq:   NP_336905.1
- RefSeq:   YP_177872.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q7D7A1
- SMR:   Q7D7A1
- EnsemblBacteria:   EBMYCT00000001087
- EnsemblBacteria:   EBMYCT00000069793
- GeneID:   888950
- GeneID:   925925
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2425
- KEGG:   mtu:Rv2356c
- TIGR:   MT2425
- TubercuList:   Rv2356c
- GeneTree:   EBGT00050000014886
- HOGENOM:   HBG572308
- OMA:   GLDDGNS
- ProtClustDB:   CLSK799899
- InterPro:   IPR002989
- InterPro:   IPR000030

Pfam domain/function: PF01469 Pentapeptide_2; PF00823 PPE

EC number: NA

Molecular weight: Translated: 58391; Mature: 58391

Theoretical pI: Translated: 3.67; Mature: 3.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNFSVLPPEINSGRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAGGSGQA
CCCCEECCCCCCCCEEEEECCCCCEEEEHHHHCCHHHHHHCCHHHHCHHECCCCCCCCCC
WQGAAAAAMVVAAAPYAGWLAAAAARAGGAAVQAKAVAGAFEAARAAMVDPVVVAANRSA
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCEEEECCHHH
FVQLVLSNVFGQNAPAIAAAEATYEQMWAADVAAMVGYHGGASAAAAALAPWQQAVPGLS
HHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCHH
GLLGGAANAPAAAAQGAAQGLAELTLNLGVGNIGSLNLGSGNIGGTNVGSGNVGGTNLGS
HHHCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
GNYGSLNWGSGNTGTGNAGSGNTGDYNPGSGNFGSGNFGSGNIGSLNVGSGNFGTLNLAN
CCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECC
GNNGDVNFGGGNTGDFNFGGGNNGTLNFGFGNTGSGNFGFGNTGNNNIGIGLTGDGQIGI
CCCCEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCEEE
GGLNSGTGNIGFGNSGNNNIGFFNSGDGNIGFFNSGDGNTGFGNAGNINTGFWNAGNLNT
CCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCC
GFGSAGNGNVGIFDGGNSNSGSFNVGFQNTGFGNSGAGNTGFFNAGDSNTGFANAGNVNT
CCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
GFFNGGDINTGGFNGGNVNTGFGSALTQAGANSGFGNLGTGNSGWGNSDPSGTGNSGFFN
CEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
TGNGNSGFSNAGPAMLPGFNSGFANIGSFNAGIANSGNNLAGISNSGDDSSGAVNSGSQN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
SGAFNAGVGLSGFFR
CCCEECCCCCCCCCC
>Mature Secondary Structure
MVNFSVLPPEINSGRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAGGSGQA
CCCCEECCCCCCCCEEEEECCCCCEEEEHHHHCCHHHHHHCCHHHHCHHECCCCCCCCCC
WQGAAAAAMVVAAAPYAGWLAAAAARAGGAAVQAKAVAGAFEAARAAMVDPVVVAANRSA
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCEEEECCHHH
FVQLVLSNVFGQNAPAIAAAEATYEQMWAADVAAMVGYHGGASAAAAALAPWQQAVPGLS
HHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCHH
GLLGGAANAPAAAAQGAAQGLAELTLNLGVGNIGSLNLGSGNIGGTNVGSGNVGGTNLGS
HHHCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
GNYGSLNWGSGNTGTGNAGSGNTGDYNPGSGNFGSGNFGSGNIGSLNVGSGNFGTLNLAN
CCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECC
GNNGDVNFGGGNTGDFNFGGGNNGTLNFGFGNTGSGNFGFGNTGNNNIGIGLTGDGQIGI
CCCCEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCEEE
GGLNSGTGNIGFGNSGNNNIGFFNSGDGNIGFFNSGDGNTGFGNAGNINTGFWNAGNLNT
CCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCC
GFGSAGNGNVGIFDGGNSNSGSFNVGFQNTGFGNSGAGNTGFFNAGDSNTGFANAGNVNT
CCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
GFFNGGDINTGGFNGGNVNTGFGSALTQAGANSGFGNLGTGNSGWGNSDPSGTGNSGFFN
CEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
TGNGNSGFSNAGPAMLPGFNSGFANIGSFNAGIANSGNNLAGISNSGDDSSGAVNSGSQN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
SGAFNAGVGLSGFFR
CCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036