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The map label for this gene is yqjI [H]

Identifier: 148823055

GI number: 148823055

Start: 2101927

End: 2103378

Strand: Reverse

Name: yqjI [H]

Synonym: TBFG_11872

Alternate gene names: 148823055

Gene position: 2103378-2101927 (Counterclockwise)

Preceding gene: 148823056

Following gene: 148823054

Centisome position: 47.54

GC content: 65.22

Gene sequence:

>1452_bases
ATGAGTTCGTCGGAATCGCCAGCCGGCATCGCGCAGATCGGCGTCACTGGCCTGGCCGTGATGGGTTCCAACATCGCCCG
AAACTTCGCCCGGCACGGCTACACCGTGGCAGTGCACAATCGGTCGGTCGCCAAGACCGACGCGCTGCTTAAGGAGCACA
GCTCAGACGGCAAGTTCGTGCGCAGTGAAACGATCCCCGAATTTCTTGCCGCACTGGAAAAACCGCGTCGGGTGCTGATC
ATGGTCAAGGCCGGAGAGGCCACTGACGCTGTCATCAACGAACTTGCTGACGCCATGGAACCCGGCGACATCATCATCGA
CGGCGGCAATGCGTTGTACACCGACACCATGCGCCGCGAGAAAGCGATGCGTGAGCGGGGCTTGCACTTCGTCGGGGCCG
GGATCTCCGGCGGCGAAGAGGGCGCGTTGAACGGGCCGTCGATCATGCCCGGCGGACCCGCCGAGTCATACCAATCGCTG
GGTCCGCTGCTCGAGGAGATCTCCGCGCATGTCGACGGCGTGCCGTGCTGCACCCACATTGGCCCGGACGGCTCCGGGCA
CTTCGTCAAGATGGTCCACAACGGCATCGAGTACTCCGACATGCAGCTCATCGGTGAGGCCTACCAGCTGATGCGCGACG
GGCTAGGTCTGACCGCGCCGGCGATCGCCGATGTGTTCACCGAGTGGAACAATGGCGATCTGGACAGCTACCTGGTCGAG
ATCACCGCCGAGGTGCTGCGGCAGACCGATGCCAAGACCGGCAAACCGCTCGTCGACGTCATCGTGGACCGGGCCGAGCA
GAAAGGCACCGGCCGTTGGACCGTCAAGTCCGCGCTGGACCTGGGTGTGCCGGTGACCGGCATCGCCGAAGCGGTGTTTG
CCCGCGCTCTCTCGGGATCCGTGGGGCAACGCTCGGCCGCCAGCGGTCTGGCTTCGGGCAAGCTCGGCGAGCAGCCCGCC
GACCCCGCCACGTTCACCGAAGACGTCCGCCAGGCGTTGTACGCCTCCAAGATCGTGGCCTACGCTCAGGGCTTCAACCA
GATCCAGGCCGGCAGCGCCGAATTCGGCTGGGACATCACGCCGGGCGACCTGGCCACCATCTGGCGTGGCGGCTGCATCA
TCCGGGCGAAGTTCCTCAACCACATCAAGGAAGCCTTTGACGCCAGCCCGAACCTGGCCAGTCTGATTGTGGCCCCGTAT
TTCCGCGGCGCCGTCGAATCGGCGATCGACAGTTGGCGGCGTGTGGTGTCGACGGCGGCCCAACTGGGTATCCCGACCCC
GGGATTCTCGTCGGCCCTGTCGTATTACGACGCGCTGCGCACCGCGCGGCTGCCCGCTGCACTCACCCAGGCCCAGCGCG
ACTTCTTCGGCGCACACACCTACGGCCGGATCGACGAACCAGGCAAGTTCCACACACTATGGAGTTCAGACCGCACCGAA
GTACCGGTGTAG

Upstream 100 bases:

>100_bases
TCCTGGTGGTGCCCACCGTCGCGCTGGCCGTACCGTGGCTCACGCAGCTGCAGCGGCTGTTCATCGCCTAGCGAAGCCGG
GCCCAACTGAAAGGCAGGAC

Downstream 100 bases:

>100_bases
CGGGCTAGAACTAAAAGGGGGTAAAGGGGTAAGTGATGAGATTTCTAGACGGGCACCCACCCGGGTACGACCTGACATAC
AACGACGTGTTCATCGTTCC

Product: 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MSSSESPAGIAQIGVTGLAVMGSNIARNFARHGYTVAVHNRSVAKTDALLKEHSSDGKFVRSETIPEFLAALEKPRRVLI
MVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRREKAMRERGLHFVGAGISGGEEGALNGPSIMPGGPAESYQSL
GPLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLIGEAYQLMRDGLGLTAPAIADVFTEWNNGDLDSYLVE
ITAEVLRQTDAKTGKPLVDVIVDRAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGSVGQRSAASGLASGKLGEQPA
DPATFTEDVRQALYASKIVAYAQGFNQIQAGSAEFGWDITPGDLATIWRGGCIIRAKFLNHIKEAFDASPNLASLIVAPY
FRGAVESAIDSWRRVVSTAAQLGIPTPGFSSALSYYDALRTARLPAALTQAQRDFFGAHTYGRIDEPGKFHTLWSSDRTE
VPV

Sequences:

>Translated_483_residues
MSSSESPAGIAQIGVTGLAVMGSNIARNFARHGYTVAVHNRSVAKTDALLKEHSSDGKFVRSETIPEFLAALEKPRRVLI
MVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRREKAMRERGLHFVGAGISGGEEGALNGPSIMPGGPAESYQSL
GPLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLIGEAYQLMRDGLGLTAPAIADVFTEWNNGDLDSYLVE
ITAEVLRQTDAKTGKPLVDVIVDRAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGSVGQRSAASGLASGKLGEQPA
DPATFTEDVRQALYASKIVAYAQGFNQIQAGSAEFGWDITPGDLATIWRGGCIIRAKFLNHIKEAFDASPNLASLIVAPY
FRGAVESAIDSWRRVVSTAAQLGIPTPGFSSALSYYDALRTARLPAALTQAQRDFFGAHTYGRIDEPGKFHTLWSSDRTE
VPV
>Mature_482_residues
SSSESPAGIAQIGVTGLAVMGSNIARNFARHGYTVAVHNRSVAKTDALLKEHSSDGKFVRSETIPEFLAALEKPRRVLIM
VKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRREKAMRERGLHFVGAGISGGEEGALNGPSIMPGGPAESYQSLG
PLLEEISAHVDGVPCCTHIGPDGSGHFVKMVHNGIEYSDMQLIGEAYQLMRDGLGLTAPAIADVFTEWNNGDLDSYLVEI
TAEVLRQTDAKTGKPLVDVIVDRAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGSVGQRSAASGLASGKLGEQPAD
PATFTEDVRQALYASKIVAYAQGFNQIQAGSAEFGWDITPGDLATIWRGGCIIRAKFLNHIKEAFDASPNLASLIVAPYF
RGAVESAIDSWRRVVSTAAQLGIPTPGFSSALSYYDALRTARLPAALTQAQRDFFGAHTYGRIDEPGKFHTLWSSDRTEV
PV

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=468, Percent_Identity=51.0683760683761, Blast_Score=463, Evalue=1e-130,
Organism=Escherichia coli, GI1788341, Length=464, Percent_Identity=53.8793103448276, Blast_Score=518, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17542558, Length=473, Percent_Identity=47.3572938689218, Blast_Score=448, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321695, Length=464, Percent_Identity=48.0603448275862, Blast_Score=455, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6321977, Length=460, Percent_Identity=49.7826086956522, Blast_Score=445, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24639279, Length=470, Percent_Identity=47.8723404255319, Blast_Score=435, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 51361; Mature: 51230

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00461 6PGD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSESPAGIAQIGVTGLAVMGSNIARNFARHGYTVAVHNRSVAKTDALLKEHSSDGKFV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCEE
RSETIPEFLAALEKPRRVLIMVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRRE
HHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCEEEHHHHHHH
KAMRERGLHFVGAGISGGEEGALNGPSIMPGGPAESYQSLGPLLEEISAHVDGVPCCTHI
HHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCC
GPDGSGHFVKMVHNGIEYSDMQLIGEAYQLMRDGLGLTAPAIADVFTEWNNGDLDSYLVE
CCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHH
ITAEVLRQTDAKTGKPLVDVIVDRAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGS
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHCCC
VGQRSAASGLASGKLGEQPADPATFTEDVRQALYASKIVAYAQGFNQIQAGSAEFGWDIT
CCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCC
PGDLATIWRGGCIIRAKFLNHIKEAFDASPNLASLIVAPYFRGAVESAIDSWRRVVSTAA
CCHHHHHHCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLGIPTPGFSSALSYYDALRTARLPAALTQAQRDFFGAHTYGRIDEPGKFHTLWSSDRTE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCC
VPV
CCC
>Mature Secondary Structure 
SSSESPAGIAQIGVTGLAVMGSNIARNFARHGYTVAVHNRSVAKTDALLKEHSSDGKFV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCEE
RSETIPEFLAALEKPRRVLIMVKAGEATDAVINELADAMEPGDIIIDGGNALYTDTMRRE
HHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCEEEHHHHHHH
KAMRERGLHFVGAGISGGEEGALNGPSIMPGGPAESYQSLGPLLEEISAHVDGVPCCTHI
HHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCC
GPDGSGHFVKMVHNGIEYSDMQLIGEAYQLMRDGLGLTAPAIADVFTEWNNGDLDSYLVE
CCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHH
ITAEVLRQTDAKTGKPLVDVIVDRAEQKGTGRWTVKSALDLGVPVTGIAEAVFARALSGS
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHCCCCHHHHHHHHHHHHHCCC
VGQRSAASGLASGKLGEQPADPATFTEDVRQALYASKIVAYAQGFNQIQAGSAEFGWDIT
CCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCC
PGDLATIWRGGCIIRAKFLNHIKEAFDASPNLASLIVAPYFRGAVESAIDSWRRVVSTAA
CCHHHHHHCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLGIPTPGFSSALSYYDALRTARLPAALTQAQRDFFGAHTYGRIDEPGKFHTLWSSDRTE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCC
VPV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]