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The map label for this gene is plcD

Identifier: 148822964

GI number: 148822964

Start: 1984678

End: 1986222

Strand: Reverse

Name: plcD

Synonym: TBFG_11775

Alternate gene names: 148822964

Gene position: 1986222-1984678 (Counterclockwise)

Preceding gene: 148822965

Following gene: 148822963

Centisome position: 44.89

GC content: 60.39

Gene sequence:

>1545_bases
GTGAGCCAAAGCCACATCGGCGGAGTTTCGCGGCGAGAATTCCTAGCTAAGGTCGCTGCGGGCGGCGCCGGCGCGTTGAT
GTCTTTCGCCGGTCCGGTGATTGAAAAGGCCTACGGCGCGGGGCCCTGCTCCGGCCATTTGACCGACATCGAACACTTTG
TGTTCTTCATGCAGGAGAACCGCTCATTCGATCACTACTTCGGAACACTCTCCGGCACCGATGGATTCAACACGGTATCG
CCGCTCTTCCAACAAAAGGGTTGGAACCCGATGACGCAGGCTCTTGACGCCACCGGCGTTACGATGCCCTACCGCTTCGA
CACCACCCGAGGCCCGTTCCTCGACGGCGCGTGTGTCAACGACCCTGACCATAGCTGGGTGGCGATGCATGAGTCGTGGA
ATGGTGGCGTCAACGACAACTGGCTACCAGCGCAGGCCAAGACTCGCTCGGCGGCCCACACTCCCACGGTGATGGGCTAC
TACACGCGCCAAGACATTCCGATCCACTATCTGTTGGCCGACGCGTTCACCGTCTGCGACCGCTACTTTTGCTCGGTATT
GGGTCCCACCCTGCCCAACCGCCTTTATTGGCTGAGCGCCACCATCGACCCCGACGGCCAAAATGGTGGGCCGGAGCTGC
AGAGTCCCACTTTCCAACCGGTGCGGAGATTCGGTTGGCGCATCATGCCGCAGAACCTTAGCGATGCCGGCGTCAGCTGG
AAGGTGTATCGCAACAAGACACTCGGGCCCATCTCCTCGGTTCTTACTTACGGCTCGCTTGTGACGTCTTTCAAACAGTC
AGCCGATCCCAGGTCAGATCTTGTCCGCTTTGGCGTGGCACCAAGCTATCCCGCGAGCTTCGCGGCCGACGTCTTAGCCA
ATAGACTGCCGCGGGTCTCCTGGGTGATTCCCAATGTTCTCGAATCCGAACATCCTGCGGTTCCAGCCGCGGCCGGGGCT
TTCGCAATCGTCAACATCTTAAGAATATTGCTTGCCAATCCTGCGGTGTGGGAAAAGACGGCGCTGATCGTCAGCTACGA
CGAAAACGGCGGCTTTTTCGACCACGTTGTTCCTGCTACCGCGCCGGCCGGGACTCCCGGCGAATATGTCACGGTGCCTG
ACATCGATCAGGTGCCGGGCTCCGGCGGAATACGCGGGCCGATCGGTTTGGGCTTTCGCGTTCCCTGCTTCGTCATTTCG
CCGTACAGCCGTGGCCCGCAGATGGTTCACGACACGTTTGACCACACCTCACAGCTGAGATTGCTCGAAACTCGGTTCGG
GGTGCCAGTTCCCAACCTCACGGCTTGGCGGCGCAGTGTGACCGGCGACATGACGTCAACGTTCAACTTCGCTGTCCCGC
CCAACTCATCATGGCCCAACCTGGATTATCCCGGGCTGCACGCGCTATCAACGGTGCCGCAGTGCGTGCCCAACGCGGCG
CTGGGCACGATAAACCGTGGAATCCCGTATCGGGTTCCTGATCCACAGATCATGCCCACGCAGGAAACCACGCCTACCCG
TGGTATTCCGAGCGGTCCGTGCTAA

Upstream 100 bases:

>100_bases
AGTTCGCGCGCGACACGCCGGTTGGCGCGTCGTGATCGTTCGTCGGAGTCCTCTACCTTGAGCTGAAATGCGGCTGGAGG
TTCGACAGGAGAACACAGCG

Downstream 100 bases:

>100_bases
GGCTCGAGGAACTCAAATCCGGTCAGGTACACGGTATTCCGTGCGGACCCGATCCAGGGACCGGGTAGCGATTGCCAGAG
CCACACCTTGTTGACCTGTC

Product: phospholipase C plcD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MSQSHIGGVSRREFLAKVAAGGAGALMSFAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYFGTLSGTDGFNTVS
PLFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHSWVAMHESWNGGVNDNWLPAQAKTRSAAHTPTVMGY
YTRQDIPIHYLLADAFTVCDRYFCSVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSW
KVYRNKTLGPISSVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVIPNVLESEHPAVPAAAGA
FAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPAGTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVIS
PYSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAA
LGTINRGIPYRVPDPQIMPTQETTPTRGIPSGPC

Sequences:

>Translated_514_residues
MSQSHIGGVSRREFLAKVAAGGAGALMSFAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYFGTLSGTDGFNTVS
PLFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHSWVAMHESWNGGVNDNWLPAQAKTRSAAHTPTVMGY
YTRQDIPIHYLLADAFTVCDRYFCSVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSW
KVYRNKTLGPISSVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVIPNVLESEHPAVPAAAGA
FAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPAGTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVIS
PYSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAA
LGTINRGIPYRVPDPQIMPTQETTPTRGIPSGPC
>Mature_513_residues
SQSHIGGVSRREFLAKVAAGGAGALMSFAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYFGTLSGTDGFNTVSP
LFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHSWVAMHESWNGGVNDNWLPAQAKTRSAAHTPTVMGYY
TRQDIPIHYLLADAFTVCDRYFCSVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWK
VYRNKTLGPISSVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVIPNVLESEHPAVPAAAGAF
AIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPAGTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVISP
YSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAAL
GTINRGIPYRVPDPQIMPTQETTPTRGIPSGPC

Specific function: Unknown

COG id: COG3511

COG function: function code M; Phospholipase C

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial phospholipase C family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHLD_MYCBO (P0A5R9)

Other databases:

- EMBL:   Y18606
- EMBL:   BX248340
- RefSeq:   NP_855436.1
- ProteinModelPortal:   P0A5R9
- EnsemblBacteria:   EBMYCT00000014521
- GeneID:   1092822
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1784c
- GeneTree:   EBGT00050000017446
- HOGENOM:   HBG565180
- OMA:   MEPQISA
- ProtClustDB:   CLSK791798
- BioCyc:   MBOV233413:MB1784C-MONOMER
- BRENDA:   3.1.4.3
- InterPro:   IPR007312
- InterPro:   IPR006311
- TIGRFAMs:   TIGR01409

Pfam domain/function: PF04185 Phosphoesterase

EC number: =3.1.4.3

Molecular weight: Translated: 55771; Mature: 55639

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS51318 TAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSHIGGVSRREFLAKVAAGGAGALMSFAGPVIEKAYGAGPCSGHLTDIEHFVFFMQEN
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
RSFDHYFGTLSGTDGFNTVSPLFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVN
CCHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCCC
DPDHSWVAMHESWNGGVNDNWLPAQAKTRSAAHTPTVMGYYTRQDIPIHYLLADAFTVCD
CCCCCEEEEECCCCCCCCCCCCCCCHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHH
RYFCSVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSW
HHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCEECCCCCCCCCCEE
KVYRNKTLGPISSVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVS
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEE
WVIPNVLESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPAT
ECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEHHCCCCC
APAGTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLR
CCCCCCCCEEECCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHCCHHHHH
LLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAA
HHHHHCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHH
LGTINRGIPYRVPDPQIMPTQETTPTRGIPSGPC
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQSHIGGVSRREFLAKVAAGGAGALMSFAGPVIEKAYGAGPCSGHLTDIEHFVFFMQEN
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
RSFDHYFGTLSGTDGFNTVSPLFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVN
CCHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCEEEECCCCCCCCCCCCCC
DPDHSWVAMHESWNGGVNDNWLPAQAKTRSAAHTPTVMGYYTRQDIPIHYLLADAFTVCD
CCCCCEEEEECCCCCCCCCCCCCCCHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHH
RYFCSVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSW
HHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCEECCCCCCCCCCEE
KVYRNKTLGPISSVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVS
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEE
WVIPNVLESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPAT
ECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEHHCCCCC
APAGTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLR
CCCCCCCCEEECCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHCCHHHHH
LLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAA
HHHHHCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHH
LGTINRGIPYRVPDPQIMPTQETTPTRGIPSGPC
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10320585; 12788972