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The map label for this gene is pimC

Identifier: 148822965

GI number: 148822965

Start: 1986351

End: 1987496

Strand: Reverse

Name: pimC

Synonym: TBFG_11776

Alternate gene names: 148822965

Gene position: 1987496-1986351 (Counterclockwise)

Preceding gene: 148822968

Following gene: 148822964

Centisome position: 44.92

GC content: 65.62

Gene sequence:

>1146_bases
ATGCGTGTTGTTCAGGTCGCCAACTTCTATGGACCTCGCTCGGGCGGACTCCGCACCGCGGTGGACCGGCTGGGCGCGGA
ATACTGCGCCAGCGGACACGAGGTGTTTTTGATCGTCCCGGGGGCGCGCACCGAACGACACCTCCTACGCACGGGTGTTG
TTCGAATTACCTTGCCCGCCAAGCATATTCCATATACCGGTGGTTATCGCGCGGTTATGCCAGGAGCCGTGCGGACTGTA
TTGGAAACACTGCGACCAGACGCCCTGGAGGTCTCCGACCGGCTCACCCTGAGGTCACTGGGCCGGTGGGGCCGCGAACA
CGGCGTTACGACGGTGATGATCTCCCACGAGCGTCTTGATCGCTTTGCGGGCCAATTGCTTCCGCGTCGAGCCGCGCAGA
AGTTCGCAGACTTCGCCAACGCGCGAACCGCCGCCAACTACGACACTGTCGTGTGTACTACCGGGTTCGCGCGCGAAGAA
TTCGACCGCATCGGAGCGACAAATACCGTCACCGTCCCACTGGGCGTAGACCTGAAGACCTTCCACCCGCGGCGGCGCTG
TGCCCGGGTTCGGCAGCACTGGGCCACCCCGACGCAGATCCTGCTGGTCCACTGCGGCCGGCTGTCGGTGGAAAAGCACG
CTGACCGCAGCATCGACGCACTCGCCGCATTGTGTGACGCCGGCGTCGACGCTCGACTGGTCATCGCTGGCGAGGGTCCG
CTGCGCGCCAGGCTGGAACGCAAGGCAACCGGGTTGCCGATCGACTTCACCGGTTTCATCTCGGATCGGCATGCCGTCGC
TGGCCTGCTGGCATCGGCCGATGTCGCATTGGCACCTGGGCCACACGAGACATTTGGGCTAGCCGCACTCGAATCGCTGG
CGTGTGGCACACCGGCCGTGGTGTCCCGCACCTCGGCGCTGACCGAGATCATCACCGCAGACAGCGGCGCCTGCGCCGAC
AACCGCCCAGAGGCCATCGCACACGCAGTCCGCACAATCGTCAGCCGGCCCGAACGCCACCGGCGCCGCTGCGCGCGCCG
CCGCGCCGAAATATTCACCTGGCAACGGGCAGCAGCCAGCATGCTAGCAACATTGGGCGCCATGGCCGTAAGCACCCGGT
GCGGCGACACCCAAGACACCGCATAG

Upstream 100 bases:

>100_bases
AGCGCAGGCAGGTGCCCGCTCCGCAGGAGTTCATGGTCCGTTCAGGGAACCGTCGATGCTATGTCGTTGACCGCACACGA
CGGCCGGTTCTGCTCACGGT

Downstream 100 bases:

>100_bases
CGGTTCAAGTTTGCGGCCGAAATCCGCAAGTTCGCGCGCGACACGCCGGTTGGCGCGTCGTGATCGTTCGTCGGAGTCCT
CTACCTTGAGCTGAAATGCG

Product: glycosyl transferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MRVVQVANFYGPRSGGLRTAVDRLGAEYCASGHEVFLIVPGARTERHLLRTGVVRITLPAKHIPYTGGYRAVMPGAVRTV
LETLRPDALEVSDRLTLRSLGRWGREHGVTTVMISHERLDRFAGQLLPRRAAQKFADFANARTAANYDTVVCTTGFAREE
FDRIGATNTVTVPLGVDLKTFHPRRRCARVRQHWATPTQILLVHCGRLSVEKHADRSIDALAALCDAGVDARLVIAGEGP
LRARLERKATGLPIDFTGFISDRHAVAGLLASADVALAPGPHETFGLAALESLACGTPAVVSRTSALTEIITADSGACAD
NRPEAIAHAVRTIVSRPERHRRRCARRRAEIFTWQRAAASMLATLGAMAVSTRCGDTQDTA

Sequences:

>Translated_381_residues
MRVVQVANFYGPRSGGLRTAVDRLGAEYCASGHEVFLIVPGARTERHLLRTGVVRITLPAKHIPYTGGYRAVMPGAVRTV
LETLRPDALEVSDRLTLRSLGRWGREHGVTTVMISHERLDRFAGQLLPRRAAQKFADFANARTAANYDTVVCTTGFAREE
FDRIGATNTVTVPLGVDLKTFHPRRRCARVRQHWATPTQILLVHCGRLSVEKHADRSIDALAALCDAGVDARLVIAGEGP
LRARLERKATGLPIDFTGFISDRHAVAGLLASADVALAPGPHETFGLAALESLACGTPAVVSRTSALTEIITADSGACAD
NRPEAIAHAVRTIVSRPERHRRRCARRRAEIFTWQRAAASMLATLGAMAVSTRCGDTQDTA
>Mature_381_residues
MRVVQVANFYGPRSGGLRTAVDRLGAEYCASGHEVFLIVPGARTERHLLRTGVVRITLPAKHIPYTGGYRAVMPGAVRTV
LETLRPDALEVSDRLTLRSLGRWGREHGVTTVMISHERLDRFAGQLLPRRAAQKFADFANARTAANYDTVVCTTGFAREE
FDRIGATNTVTVPLGVDLKTFHPRRRCARVRQHWATPTQILLVHCGRLSVEKHADRSIDALAALCDAGVDARLVIAGEGP
LRARLERKATGLPIDFTGFISDRHAVAGLLASADVALAPGPHETFGLAALESLACGTPAVVSRTSALTEIITADSGACAD
NRPEAIAHAVRTIVSRPERHRRRCARRRAEIFTWQRAAASMLATLGAMAVSTRCGDTQDTA

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of the alpha-1,6-linked mannose residue of the triacyl phosphatidylinositol dimannoside (Ac3PIM2) to generate triacyl phosphatidylinositol trimannoside (Ac3PIM3)

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PIMC_MYCTA (A5U3B9)

Other databases:

- EMBL:   AJ242907
- EMBL:   CP000611
- RefSeq:   YP_001283081.1
- ProteinModelPortal:   A5U3B9
- STRING:   A5U3B9
- EnsemblBacteria:   EBMYCT00000065954
- GeneID:   5212121
- GenomeReviews:   CP000611_GR
- KEGG:   mra:MRA_1768B
- eggNOG:   COG0438
- GeneTree:   EBGT00050000015522
- HOGENOM:   HBG726846
- OMA:   PAETFGL
- ProtClustDB:   CLSK881393
- BioCyc:   MTUB419947:MRA_1768B-MONOMER
- InterPro:   IPR001296

Pfam domain/function: PF00534 Glycos_transf_1

EC number: =2.4.1.57

Molecular weight: Translated: 41290; Mature: 41290

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: BINDING 16-16 BINDING 207-207 BINDING 291-291

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVQVANFYGPRSGGLRTAVDRLGAEYCASGHEVFLIVPGARTERHLLRTGVVRITLPA
CCEEEEECCCCCCCCCHHHHHHHHCHHHHCCCCEEEEEECCCCHHHHHHHHCCEEEEECC
KHIPYTGGYRAVMPGAVRTVLETLRPDALEVSDRLTLRSLGRWGREHGVTTVMISHERLD
CCCCCCCCCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHH
RFAGQLLPRRAAQKFADFANARTAANYDTVVCTTGFAREEFDRIGATNTVTVPLGVDLKT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHCCCCCEEEEEECCCHHH
FHPRRRCARVRQHWATPTQILLVHCGRLSVEKHADRSIDALAALCDAGVDARLVIAGEGP
CCHHHHHHHHHHHCCCCHHEEEECCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEEECCCC
LRARLERKATGLPIDFTGFISDRHAVAGLLASADVALAPGPHETFGLAALESLACGTPAV
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHCCCHHH
VSRTSALTEIITADSGACADNRPEAIAHAVRTIVSRPERHRRRCARRRAEIFTWQRAAAS
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MLATLGAMAVSTRCGDTQDTA
HHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRVVQVANFYGPRSGGLRTAVDRLGAEYCASGHEVFLIVPGARTERHLLRTGVVRITLPA
CCEEEEECCCCCCCCCHHHHHHHHCHHHHCCCCEEEEEECCCCHHHHHHHHCCEEEEECC
KHIPYTGGYRAVMPGAVRTVLETLRPDALEVSDRLTLRSLGRWGREHGVTTVMISHERLD
CCCCCCCCCHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHH
RFAGQLLPRRAAQKFADFANARTAANYDTVVCTTGFAREEFDRIGATNTVTVPLGVDLKT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHCCCCCEEEEEECCCHHH
FHPRRRCARVRQHWATPTQILLVHCGRLSVEKHADRSIDALAALCDAGVDARLVIAGEGP
CCHHHHHHHHHHHCCCCHHEEEECCCCCCHHHHCCCHHHHHHHHHHCCCCEEEEEECCCC
LRARLERKATGLPIDFTGFISDRHAVAGLLASADVALAPGPHETFGLAALESLACGTPAV
HHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHCCCHHH
VSRTSALTEIITADSGACADNRPEAIAHAVRTIVSRPERHRRRCARRRAEIFTWQRAAAS
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MLATLGAMAVSTRCGDTQDTA
HHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10531227