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The map label for this gene is 148822541

Identifier: 148822541

GI number: 148822541

Start: 1487624

End: 1489300

Strand: Reverse

Name: 148822541

Synonym: TBFG_11350

Alternate gene names: NA

Gene position: 1489300-1487624 (Counterclockwise)

Preceding gene: 148822542

Following gene: 148822540

Centisome position: 33.66

GC content: 64.1

Gene sequence:

>1677_bases
ATGCCGGCGAAAAAGACCATGGCGCAACGCCTGGGCCAGGCACTCGAGACGATGACCCGTCAGTGCGGCCAGCTGCCCGA
GACCCCGGCGTATGGCTCCTGGTTGCTTGGGCGGGTGTCAGAAAGCCCGTCGCGTCGCTGGGTACGCATCAAGCGCATCG
TGACCGTCTATATCATGACGGCGAACCTGACCGGGATCGTGGTCGCGCTGCTAGTGGTGACCTTCGCTTTTCCGGTGCCT
AGCATCTACACCGACGCCCCATGGTGGGTCACCTTCGGGGTCGCACCGGCCTATGCGACGCTCGCACTGGCCATCGGCAC
CTACTGGATAACCACGCGAATCGTCAGAGCGTCCATACGGTGGGCGATCGAGGAACGCGCGCCGAGCCAGGCCGACGGGC
GCAACACCTTGCTGCTCCCGTTTCGAGTGGCAGCCGTCCACCTCATTCTGTGGGATATCGGCGGGGCGTTGTTGGCCACG
CTCTACGGGCTGGCCAACCGCGTATTCGTCACCATAATTTTGTTCTCGGTGACTATCTGCGGCGTTTTGGTAGCCACCAA
TTGCTACTTGTTCACCGAGTTCGCGCTGCGACCCGTAGCCGCTAAAGCACTCGAAGCGGGACGACCGCCACGACGGTTTG
CACCGGGCATCATGGGCCGAACGATGACGGTGTGGTCGCTAGGTTCAGGCGTGCCTGTGACCGGCATCGCCACGACAGCG
CTCTACGTCCTATTGGTGCACAATCTGACCGAAACGCAGCTCGCGTCGGCGGTGTTGATCCTGTCGATAACCACGTTGAT
CTTCGGGTTTCTCGTGATGTGGATTCTTGCTTGGCTGACGGCGGCGCCGGTGCGAGTGGTGCGCGCTGCGCTCAAGCGTG
TCGAGCAGGGGGATCTGCGAGGGGATCTGGTGGTGTTCGACGGCACCGAACTCGGTGAGCTGCAGCGTGGTTTCAACGCG
ATGGTCAACGGCCTGCGCGAGCGCGAACGCGTGCGCGACCTTTTCGGCCGCCACGTCGGACGCGAAGTCGCCGCCGCCGC
CGAGCGTGAACGACCACAGCTAGGCGGCGAAGACCGCCACGCCGCCGTCGTCTTCGTCGACATCGTCGGCTCCACCCAGC
TGGTGGACAACCAACCTGCCGCCCACGTGGTCAAGCTCCTCAACCGGTTTTTCGCGATCGTCGTCAACGAGGTCGACCGT
CACCACGGACTGATCAACAAGTTCGCAGGCGACGCCGCCCTGGCCATCTTCGGAGCCCCGAACCGCCTCGACCGTCCCGA
AGACGCCGCGCTGGCCGCCGCCCGGGCCATAGCCGAGCGGCTGGCCAACGAGATGCCCGAGGTCCAAGCCGGCATCGGGG
TGGCGGCAGGCCAGATCGTCGCCGGCAATGTCGGCGCCAAGCAAAGATTCGAATACACAGTGGTCGGCAAGCCGGTCAAC
CAGGCGGCCCGATTGTGCGAACTGGCCAAATCACACCCCGCGCGATTGCTAGCATCCTCGGACACACTGCACGCTGCCAG
CGAAACCGAACGTGCCCATTGGTCTTTGGGCGAAACCGTGACGCTGCGCGGTTACCACCAGCCCACCCAACTAGCCTCGC
CGCATCGGCGGCCACCGGGAAGCATCCACCTCACCGCAGAGCATGCCGAGGAAATCAGGACCGACAGATTAGGCTGA

Upstream 100 bases:

>100_bases
GCCTGCTCAGTCGGCCGACATAGTCGGCGGTGCACTGGGCGATCACCAGACCCACACGATTTACCGTGGGGCGCATCCGA
CAGATTAGGCTGACGCCACC

Downstream 100 bases:

>100_bases
CCCACCATGTCCAAGACGCGGGAGCAACGCCTGCGCCGGGTTCTGGAGACGATGACCCGTCAGCACGACCGGCTGCGAGA
TCCGCCCGCGTACGGCTCCT

Product: adenylate cyclase

Products: 3',5'-cyclic AMP; diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGIVVALLVVTFAFPVP
SIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLAT
LYGLANRVFVTIILFSVTICGVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA
LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNA
MVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDR
HHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN
QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASPHRRPPGSIHLTAEHAEEIRTDRLG

Sequences:

>Translated_558_residues
MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGIVVALLVVTFAFPVP
SIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLAT
LYGLANRVFVTIILFSVTICGVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA
LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNA
MVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDR
HHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN
QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASPHRRPPGSIHLTAEHAEEIRTDRLG
>Mature_557_residues
PAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMTANLTGIVVALLVVTFAFPVPS
IYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIRWAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATL
YGLANRVFVTIILFSVTICGVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTAL
YVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAM
VNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRH
HGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQ
AARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASPHRRPPGSIHLTAEHAEEIRTDRLG

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: 4.6.1.1

Molecular weight: Translated: 60736; Mature: 60605

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHEEHHHH
ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC
HHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEECCCCCCCHHHHHHH
LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP
EEEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
NRLDRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEECCCCCCCCEEEEEECCCHH
QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASPHRRPPG
HHHHHHHHHHCCCHHEEECCCCHHCCHHCCHHHCCCCCEEEEECCCCCHHHCCCCCCCCC
SIHLTAEHAEEIRTDRLG
CEEEEHHHHHHHHHCCCC
>Mature Secondary Structure 
PAKKTMAQRLGQALETMTRQCGQLPETPAYGSWLLGRVSESPSRRWVRIKRIVTVYIMT
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHEEHHHH
ANLTGIVVALLVVTFAFPVPSIYTDAPWWVTFGVAPAYATLALAIGTYWITTRIVRASIR
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
WAIEERAPSQADGRNTLLLPFRVAAVHLILWDIGGALLATLYGLANRVFVTIILFSVTIC
HHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLVATNCYLFTEFALRPVAAKALEAGRPPRRFAPGIMGRTMTVWSLGSGVPVTGIATTA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEECCCCCCCHHHHHHH
LYVLLVHNLTETQLASAVLILSITTLIFGFLVMWILAWLTAAPVRVVRAALKRVEQGDLR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GDLVVFDGTELGELQRGFNAMVNGLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRH
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAP
EEEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
NRLDRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVN
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEECCCCCCCCEEEEEECCCHH
QAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGYHQPTQLASPHRRPPG
HHHHHHHHHHCCCHHEEECCCCHHCCHHCCHHHCCCCCEEEEECCCCCHHHCCCCCCCCC
SIHLTAEHAEEIRTDRLG
CEEEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP

Specific reaction: ATP = 3',5'-cyclic AMP + diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]