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The map label for this gene is 148822540

Identifier: 148822540

GI number: 148822540

Start: 1486616

End: 1487617

Strand: Reverse

Name: 148822540

Synonym: TBFG_11349

Alternate gene names: NA

Gene position: 1487617-1486616 (Counterclockwise)

Preceding gene: 148822541

Following gene: 148822537

Centisome position: 33.62

GC content: 63.87

Gene sequence:

>1002_bases
ATGTCCAAGACGCGGGAGCAACGCCTGCGCCGGGTTCTGGAGACGATGACCCGTCAGCACGACCGGCTGCGAGATCCGCC
CGCGTACGGCTCCTGGCTGCTTGGGTGGGTGTCAGAACGCCCGCTCCGCCGCCGGGTGCGGATTCAGATCATCCTGACCA
TCGCCCTCATCACAGCAAACCTGGTAGGGATCGGCCTGGCTGTGCTGTTAGAAAATGTCGCTTTTCCGACACCTAGCATC
GTCAGCGACGCACCCTTGTGGATCACGTTCGTGGCCGGACCCGCTTATACGGTCATCGGGATGGCGTTGGGCAGCTACTA
CGTCAAGGTGCAGACCTTGGCCGCGCTACGGTGGGCGAGCGAGGAACACACGCCAAGTCGGGCCGACCAACGCAACACCC
TGCTGGCCCCGCTGCGGGTGGCGGTCGGGACCCTCATCCTGTGGGCAGTCGGAGCGGCGTTGTTTACCACCCTCTACGGG
TTGGCTAACCGCCTATTCATCCCGCAGGTCATGTTCTCGACACTGTTTTGCGGCGTTCTGGTCGCCACCGCCTGCTACAT
GCTCACCGAGTTCGCTCTGCGCCCGGTGGCCGCCCAGGCACTCGAGGCCGGGCTACCGCCGGGACGGTTCGCACTGGGAA
TCATCGGCCGGACCATGGTGGTGTGGCTGCTCAGCTCGGGCGTGCCGCTCTTCGGTATCGCCTTGCTAGGGATCCTTGAG
ATGGTGCTGCAGAACTTCACCGACATCCAGTTCGCATACGGTGTGCTGATCGTGTCGTCGGCAACGCTGATCGGCGGGTT
CCTTTTGATGTGGATCATGTCGTGGCTGACGGCGGCGCCGGTGCGAGTGGTGCGCGCTGCGCTCAAGCGTGTCGAGCAGG
GGGATCTGCGAGGGGATCTGGTGGTGTTCGACGGCACCGAACTCGGTGAGCTGCAGCGTGGTTTCAACGCGATGGTCAAC
GGCCTGAACCGCCCCGGTGAGTCCGGAGACTCTCTGATCTGA

Upstream 100 bases:

>100_bases
CACCCAACTAGCCTCGCCGCATCGGCGGCCACCGGGAAGCATCCACCTCACCGCAGAGCATGCCGAGGAAATCAGGACCG
ACAGATTAGGCTGACCCACC

Downstream 100 bases:

>100_bases
GACCTCAGCCGGCGGCTGGTCTCTGGCGTTGAGCGTAGTAGGCAGCCTCGAGTTCGACCGGCGGGACGTCGCCGCAGTAC
TGGTAGAGGCGGCGATGGTT

Product: adenylate cyclase

Products: 3',5'-cyclic AMP; diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSKTREQRLRRVLETMTRQHDRLRDPPAYGSWLLGWVSERPLRRRVRIQIILTIALITANLVGIGLAVLLENVAFPTPSI
VSDAPLWITFVAGPAYTVIGMALGSYYVKVQTLAALRWASEEHTPSRADQRNTLLAPLRVAVGTLILWAVGAALFTTLYG
LANRLFIPQVMFSTLFCGVLVATACYMLTEFALRPVAAQALEAGLPPGRFALGIIGRTMVVWLLSSGVPLFGIALLGILE
MVLQNFTDIQFAYGVLIVSSATLIGGFLLMWIMSWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAMVN
GLNRPGESGDSLI

Sequences:

>Translated_333_residues
MSKTREQRLRRVLETMTRQHDRLRDPPAYGSWLLGWVSERPLRRRVRIQIILTIALITANLVGIGLAVLLENVAFPTPSI
VSDAPLWITFVAGPAYTVIGMALGSYYVKVQTLAALRWASEEHTPSRADQRNTLLAPLRVAVGTLILWAVGAALFTTLYG
LANRLFIPQVMFSTLFCGVLVATACYMLTEFALRPVAAQALEAGLPPGRFALGIIGRTMVVWLLSSGVPLFGIALLGILE
MVLQNFTDIQFAYGVLIVSSATLIGGFLLMWIMSWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAMVN
GLNRPGESGDSLI
>Mature_332_residues
SKTREQRLRRVLETMTRQHDRLRDPPAYGSWLLGWVSERPLRRRVRIQIILTIALITANLVGIGLAVLLENVAFPTPSIV
SDAPLWITFVAGPAYTVIGMALGSYYVKVQTLAALRWASEEHTPSRADQRNTLLAPLRVAVGTLILWAVGAALFTTLYGL
ANRLFIPQVMFSTLFCGVLVATACYMLTEFALRPVAAQALEAGLPPGRFALGIIGRTMVVWLLSSGVPLFGIALLGILEM
VLQNFTDIQFAYGVLIVSSATLIGGFLLMWIMSWLTAAPVRVVRAALKRVEQGDLRGDLVVFDGTELGELQRGFNAMVNG
LNRPGESGDSLI

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: 4.6.1.1

Molecular weight: Translated: 36407; Mature: 36275

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTREQRLRRVLETMTRQHDRLRDPPAYGSWLLGWVSERPLRRRVRIQIILTIALITAN
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LVGIGLAVLLENVAFPTPSIVSDAPLWITFVAGPAYTVIGMALGSYYVKVQTLAALRWAS
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
EEHTPSRADQRNTLLAPLRVAVGTLILWAVGAALFTTLYGLANRLFIPQVMFSTLFCGVL
CCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VATACYMLTEFALRPVAAQALEAGLPPGRFALGIIGRTMVVWLLSSGVPLFGIALLGILE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MVLQNFTDIQFAYGVLIVSSATLIGGFLLMWIMSWLTAAPVRVVRAALKRVEQGDLRGDL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVFDGTELGELQRGFNAMVNGLNRPGESGDSLI
EEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SKTREQRLRRVLETMTRQHDRLRDPPAYGSWLLGWVSERPLRRRVRIQIILTIALITAN
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LVGIGLAVLLENVAFPTPSIVSDAPLWITFVAGPAYTVIGMALGSYYVKVQTLAALRWAS
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
EEHTPSRADQRNTLLAPLRVAVGTLILWAVGAALFTTLYGLANRLFIPQVMFSTLFCGVL
CCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VATACYMLTEFALRPVAAQALEAGLPPGRFALGIIGRTMVVWLLSSGVPLFGIALLGILE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MVLQNFTDIQFAYGVLIVSSATLIGGFLLMWIMSWLTAAPVRVVRAALKRVEQGDLRGDL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VVFDGTELGELQRGFNAMVNGLNRPGESGDSLI
EEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP

Specific reaction: ATP = 3',5'-cyclic AMP + diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]