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The map label for this gene is 148822537

Identifier: 148822537

GI number: 148822537

Start: 1484661

End: 1485314

Strand: Reverse

Name: 148822537

Synonym: TBFG_11346

Alternate gene names: NA

Gene position: 1485314-1484661 (Counterclockwise)

Preceding gene: 148822540

Following gene: 148822536

Centisome position: 33.57

GC content: 67.43

Gene sequence:

>654_bases
ATGCCGGGGCGGTTCAGCCTGCGCGAGCGCGAACGCGTGCGCGACCTTTTCGGCCGCCACGTCGGACGCGAAGTCGCCGC
CGCCGCCGAGCGTGAACGACCACAGCTAGGCGGCGAAGACCGCCACGCCGCCGTCGTCTTCGTCGACATCGTCGGCTCCA
CCCAGCTGGTGGACAACCAACCTGCCGCCCACGTGGTCAAGCTCCTCAACCGGTTTTTCGCGATCGTCGTCAACGAGGTC
GACCGTCACCACGGACTGATCAACAAGTTCGCAGGCGACGCCGCCCTGGCCATCTTCGGAGCCCCGAACCGCCTCGACCG
TCCCGAAGACGCCGCGCTGGCCGCCGCCCGGGCCATAGCCGAGCGGCTGGCCAACGAGATGCCCGAGGTCCAAGCCGGCA
TCGGGGTGGCGGCAGGCCAGATCGTCGCCGGCAATGTCGGCGCCAAGCAAAGATTCGAATACACAGTGGTCGGCAAGCCG
GTCAACCAGGCGGCCCGATTGTGCGAACTGGCCAAATCACACCCCGCGCGATTGCTAGCATCCTCGGACACACTGCACGC
TGCCAGCGAAACCGAGCGTGCCCATTGGTCTTTGGGCGAGACGGTGACGCTGCGCGGACATGAGCAGCCGACTCGGCTGG
CCGTGCCCACCTAA

Upstream 100 bases:

>100_bases
GCGACCATCCGCACCGCCCGCTCACGCAGCTCCGGCGGGTACCTCCTCGATGAACCACCTGACATGACCCCATCCTTTCC
AAGAACTGGAGTCTCCGGAC

Downstream 100 bases:

>100_bases
GCCGGGCAAACAACACGAGCGCGCCAACCGGTCGCACCCGACTCTTCGACAAACTAGTCTGACGCCACAATGTCGGCCAA
GAAGAGCACGGCGCAACGCT

Product: adenylate cyclase

Products: 3',5'-cyclic AMP; diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MPGRFSLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEV
DRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKP
VNQAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT

Sequences:

>Translated_217_residues
MPGRFSLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEV
DRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKP
VNQAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT
>Mature_216_residues
PGRFSLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQPAAHVVKLLNRFFAIVVNEVD
RHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIAERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPV
NQAARLCELAKSHPARLLASSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: 4.6.1.1

Molecular weight: Translated: 23432; Mature: 23301

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGRFSLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCEECCCC
PAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
ERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLCELAKSHPARLLA
HHHHHHCCHHHHCCCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHEEE
SSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEECCCC
>Mature Secondary Structure 
PGRFSLRERERVRDLFGRHVGREVAAAAERERPQLGGEDRHAAVVFVDIVGSTQLVDNQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCEECCCC
PAAHVVKLLNRFFAIVVNEVDRHHGLINKFAGDAALAIFGAPNRLDRPEDAALAAARAIA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
ERLANEMPEVQAGIGVAAGQIVAGNVGAKQRFEYTVVGKPVNQAARLCELAKSHPARLLA
HHHHHHCCHHHHCCCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHEEE
SSDTLHAASETERAHWSLGETVTLRGHEQPTRLAVPT
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP

Specific reaction: ATP = 3',5'-cyclic AMP + diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]