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The map label for this gene is PE_PGRS36 [H]

Identifier: 148822189

GI number: 148822189

Start: 1098847

End: 1100220

Strand: Reverse

Name: PE_PGRS36 [H]

Synonym: TBFG_10998

Alternate gene names: 148822189

Gene position: 1100220-1098847 (Counterclockwise)

Preceding gene: 148822194

Following gene: 148822187

Centisome position: 24.87

GC content: 71.11

Gene sequence:

>1374_bases
ATGTCGTTTGTCAACGTGGCCCCACAGTTAGTGTCCACAGCCGCGGCCGATGCAGCGCGGATCGGCTCGGCGATCAACAC
CGCCAACACCGCGGCGGCGGCGACCACCCAGGTGTTGGCCGCCGCCCACGACGAGGTGTCAACGGCGATCGCCGCGCTGT
TCGGCAGCCACGGCCAGCACTATCAAGCGATCAGCGCGCAGGTCGCGGCCTATCAGCAACGGTTCGTGCTGGCCTTAAGC
CAAGCTGGCAGCACCTACGCGGTCGCCGAAGCGGCCAGCGCAACACCGCTGCAGAACGTGCTCGATGCGATCAACGCACC
CGTTCAGTCGCTGACCGGGCGCCCATTGATCGGCGACGGCGCGAACGGGATCGACGGGACCGGGCAAGCCGGCGGTAACG
GCGGGTGGCTGTGGGGCAACGGCGGCAACGGCGGGTCGGGGGCACCCGGGCAGGCCGGCGGGGCCGGCGGTGCGGCCGGG
TTGATCGGCAACGGTGGGGCCGGCGGAGCTGGCGGCCAGGGCCTACCCTTTGAGGCCGGCGCGAACGGCGGAGCCGGCGG
CGCCGGTGGATGGCTGTTCGGCAACGGCGGGGCCGGTGGTGTCGGCGGGGCCGGCGGAGCCGGCACAACCTTCGGTGTGG
CCGGCGGTGACGGTGGCACCGGCGGGGTTGGTGGTCACGGCGGGTTAATCGGTGTGGGTGGACACGGCGGGGACGGCGGG
ACCGGCGGCACCGGCGGCGCGGTCAGCCTCGCCCGCGCCGGCACGGCCGGCGGTGCCGGCGGCGGCCCGGTCGGCGGTAT
CGGCGGTGCGGGTGGGGTCGGCGGTGCCGGTGGGGCCGCCGGCGCCGTCACCACCATCACCCACGCCAGCTTCAACGATC
CGCACGGGGTGGCGGTCAACCCGGGCGGCAACATCTACGTCACCAACCAGGGCAGCAACACGGTGTCGGTGATCGACCCG
GTCACCAACACCGTCACCGGCTCCATCACCGACGGCAACGGTCCAAGCGGGGTGGCGGTCAGCCCCGTCACCGGCCTGGT
CTTCGTGACCAACTTCGACAGCAACACGGTGTCGGTGATCGACCCGAACACCAACACCGTCACCGGCTCCATCCCCGTCG
GTACCGGTGCGTATGGGGTGGCGGTCAACCCAGGCGGCAACATCTACGTCACCAACCAGTTCAGCAACACGGTGTCGGTG
ATCGACCCGGCCACCAACACCGTCACCGGCTCCCCCATCCCCGTCGGACTCGACCCGACAGGGGTGGCGGTCAACCCCGT
CACCGGCGTGGTCTACGTCACTAACTCTCTCGACGACACGGTGTCGGTGATCACCGGAGAGCCGGCGCGCTCGGTGTGTT
CGGCGGCCATATGA

Upstream 100 bases:

>100_bases
TGGAACGGCAGGGATCGTCCGAATAAACGGTTACCCACCGCGGCGGTAACAGGCGGTGGGCCGCCCGCATCTCAACATCG
TCGCGGTCAGGAGGATTTCG

Downstream 100 bases:

>100_bases
TCGTCGGCCGCCGGCGCGTCAGCGCTTATCGAAATCGATGAGGCCGAGCCGGGCGGCCTTGAGCAAGCGCCGAGGCACCT
TGTGGGCGTGACCGGCGACG

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAHDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVLALS
QAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAG
LIGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGG
TGGTGGAVSLARAGTAGGAGGGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNIYVTNQGSNTVSVIDP
VTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSV
IDPATNTVTGSPIPVGLDPTGVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI

Sequences:

>Translated_457_residues
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAHDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVLALS
QAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAG
LIGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGG
TGGTGGAVSLARAGTAGGAGGGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNIYVTNQGSNTVSVIDP
VTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSV
IDPATNTVTGSPIPVGLDPTGVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI
>Mature_456_residues
SFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAHDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVLALSQ
AGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDGANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGL
IGNGGAGGAGGQGLPFEAGANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGGT
GGTGGAVSLARAGTAGGAGGGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNIYVTNQGSNTVSVIDPV
TNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSVI
DPATNTVTGSPIPVGLDPTGVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI

Specific function: Unknown

COG id: COG3391

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 42072; Mature: 41941

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS51125 NHL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAHDEVSTAIAALFGSHGQH
CCHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
YQAISAQVAAYQQRFVLALSQAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDG
HHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHCCCCEECCC
ANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGAGGQGLPFEAG
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCC
ANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGG
CCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCC
TGGTGGAVSLARAGTAGGAGGGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVN
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEC
PGGNIYVTNQGSNTVSVIDPVTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVI
CCCCEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCEEECCCEEEEEEEECCCCEEEEE
DPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSVIDPATNTVTGSPIPVGLDPT
CCCCCEEEEECCCCCCCEEEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCEEECCCCC
GVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI
CEEECCCEEEEEEECCCCCEEEEEECCCHHHHHHHCC
>Mature Secondary Structure 
SFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAHDEVSTAIAALFGSHGQH
CHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
YQAISAQVAAYQQRFVLALSQAGSTYAVAEAASATPLQNVLDAINAPVQSLTGRPLIGDG
HHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHCCCCEECCC
ANGIDGTGQAGGNGGWLWGNGGNGGSGAPGQAGGAGGAAGLIGNGGAGGAGGQGLPFEAG
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCC
ANGGAGGAGGWLFGNGGAGGVGGAGGAGTTFGVAGGDGGTGGVGGHGGLIGVGGHGGDGG
CCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCC
TGGTGGAVSLARAGTAGGAGGGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVN
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEC
PGGNIYVTNQGSNTVSVIDPVTNTVTGSITDGNGPSGVAVSPVTGLVFVTNFDSNTVSVI
CCCCEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCEEECCCEEEEEEEECCCCEEEEE
DPNTNTVTGSIPVGTGAYGVAVNPGGNIYVTNQFSNTVSVIDPATNTVTGSPIPVGLDPT
CCCCCEEEEECCCCCCCEEEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCEEECCCCC
GVAVNPVTGVVYVTNSLDDTVSVITGEPARSVCSAAI
CEEECCCEEEEEEECCCCCEEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]