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The map label for this gene is PE_PGRS35 [H]

Identifier: 148822187

GI number: 148822187

Start: 1097184

End: 1098125

Strand: Reverse

Name: PE_PGRS35 [H]

Synonym: TBFG_10996

Alternate gene names: 148822187

Gene position: 1098125-1097184 (Counterclockwise)

Preceding gene: 148822189

Following gene: 148822185

Centisome position: 24.82

GC content: 71.02

Gene sequence:

>942_bases
ATGTCGTTTGTCAACGTGGCCCCACAGTTAGTGTCCACAGCCGCGGCCGATGCAGCGCGGATCGGCTCGGCGATCAACAC
CGCCAACACCGCGGCGGCGGCGACCACCCAGGTGTTGGCCGCCGCCCAAGACGAGGTGTCAACGGCGATCGCCGCGCTGT
TCGGCAGCCACGGCCAGCACTATCAAGCGATCAGCGCGCAGGTCGCGGCCTATCAGCAACGGTTCGTGCTGGCCTTAAGC
CAAGCTGGCAGCACCTACGCGGTCGCCGAAGCGGCCAGCGCAACACCGCTGCAGCAGATCGAGCAGGCCCTGTTGGGGGT
GATCAACACGCCGACTGAGGCGCTGGTGGGGCGCAAGCTGATCGGTGACGGCGCCCACGGGGCGCCCGGCACCGGGCAGG
CCGGCGGCGCCGGCGGGGCGGCCGGGTTGATCGGCAACGGTGGGGCCGGCGGCACCGGCGGCGCGGTCAGCCTCGCCCGC
GCCGGCACGGCCGGCGGTGCCGGCCGCGGCCCGGTCGGCGGTATCGGCGGTGCGGGTGGGGTCGGCGGTGCCGGTGGGGC
CGCCGGCGCCGTCACCACCATCACCCACGCCAGCTTCAACGATCCGCACGGGGTGGCGGTCAACCCGGGCGGCAACGTCT
ACGTCACCAATTTCGGCAGCGGCACGGTGTCGGTGATCAACCCCGCCACCAACACCGTCACCGGCTCCCCCATCACCATC
GGCAACGGTCCAAGCGGGGTGGCGGTCAGCCCCGTCACCGGCCTGGTCTTCGTGACCAACTTCGACAGCAACACGGTGTC
GGTGATCGACCCGACCACCAACACCGTCACCGGCTCCCCCATCACCGTCGGCACCGCTCCGACCGGGGTGGCGGTCAACC
CCGTCACCGGCGAGGTCTATGTCACCAACTTCGCCGGCGACACGGTGTCGGTAATCAGCTGA

Upstream 100 bases:

>100_bases
TGGAACGGCAGGGATCGTCCGAATAAACGGTTACCCACCGCGGCGGTAACAGGCGGTGGGCCGCCCGCATCTCAACATCG
TGGCGGTCAGGAGGATTTCG

Downstream 100 bases:

>100_bases
CACCAGCCCGCCCGGTGTGTTCGGCCCGCACCCGTCCGACCGGGCCCTCCACTGCGAGCGCCGGCTTCGGGTGTTCGCGC
GCGACTTTCTGCGCGTGGGC

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVLALS
QAGSTYAVAEAASATPLQQIEQALLGVINTPTEALVGRKLIGDGAHGAPGTGQAGGAGGAAGLIGNGGAGGTGGAVSLAR
AGTAGGAGRGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNVYVTNFGSGTVSVINPATNTVTGSPITI
GNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPTTNTVTGSPITVGTAPTGVAVNPVTGEVYVTNFAGDTVSVIS

Sequences:

>Translated_313_residues
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVLALS
QAGSTYAVAEAASATPLQQIEQALLGVINTPTEALVGRKLIGDGAHGAPGTGQAGGAGGAAGLIGNGGAGGTGGAVSLAR
AGTAGGAGRGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNVYVTNFGSGTVSVINPATNTVTGSPITI
GNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPTTNTVTGSPITVGTAPTGVAVNPVTGEVYVTNFAGDTVSVIS
>Mature_312_residues
SFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQHYQAISAQVAAYQQRFVLALSQ
AGSTYAVAEAASATPLQQIEQALLGVINTPTEALVGRKLIGDGAHGAPGTGQAGGAGGAAGLIGNGGAGGTGGAVSLARA
GTAGGAGRGPVGGIGGAGGVGGAGGAAGAVTTITHASFNDPHGVAVNPGGNVYVTNFGSGTVSVINPATNTVTGSPITIG
NGPSGVAVSPVTGLVFVTNFDSNTVSVIDPTTNTVTGSPITVGTAPTGVAVNPVTGEVYVTNFAGDTVSVIS

Specific function: Unknown

COG id: COG3391

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 29558; Mature: 29427

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS51125 NHL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQH
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
YQAISAQVAAYQQRFVLALSQAGSTYAVAEAASATPLQQIEQALLGVINTPTEALVGRKL
HHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
IGDGAHGAPGTGQAGGAGGAAGLIGNGGAGGTGGAVSLARAGTAGGAGRGPVGGIGGAGG
HCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
VGGAGGAAGAVTTITHASFNDPHGVAVNPGGNVYVTNFGSGTVSVINPATNTVTGSPITI
CCCCCCCCCCEEEEEECCCCCCCCEEECCCCCEEEEEECCCEEEEECCCCCCCCCCCEEE
GNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPTTNTVTGSPITVGTAPTGVAVNPVTGEVY
CCCCCCCEECCCEEEEEEEECCCCEEEEECCCCCCCCCCCEEECCCCCCEEECCCCCEEE
VTNFAGDTVSVIS
EEEECCCEEEECC
>Mature Secondary Structure 
SFVNVAPQLVSTAAADAARIGSAINTANTAAAATTQVLAAAQDEVSTAIAALFGSHGQH
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
YQAISAQVAAYQQRFVLALSQAGSTYAVAEAASATPLQQIEQALLGVINTPTEALVGRKL
HHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
IGDGAHGAPGTGQAGGAGGAAGLIGNGGAGGTGGAVSLARAGTAGGAGRGPVGGIGGAGG
HCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
VGGAGGAAGAVTTITHASFNDPHGVAVNPGGNVYVTNFGSGTVSVINPATNTVTGSPITI
CCCCCCCCCCEEEEEECCCCCCCCEEECCCCCEEEEEECCCEEEEECCCCCCCCCCCEEE
GNGPSGVAVSPVTGLVFVTNFDSNTVSVIDPTTNTVTGSPITVGTAPTGVAVNPVTGEVY
CCCCCCCEECCCEEEEEEEECCCCEEEEECCCCCCCCCCCEEECCCCCCEEECCCCCEEE
VTNFAGDTVSVIS
EEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]