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The map label for this gene is 148821227

Identifier: 148821227

GI number: 148821227

Start: 39978

End: 41303

Strand: Reverse

Name: 148821227

Synonym: TBFG_10036

Alternate gene names: NA

Gene position: 41303-39978 (Counterclockwise)

Preceding gene: 148821229

Following gene: 148821226

Centisome position: 0.93

GC content: 67.72

Gene sequence:

>1326_bases
GTGCCCAGGGTGGAAGTGGGTTTAGTGATTCACTCCCGGATGCACGCACGCGCACCCGTCGACGTTTGGCGGTCGGTGCG
CAGCTTGCCCGACTTCTGGCGTCTGCTGCAGGTGCGGGTTGCGAGTCAGTTCGGCGACGGGTTGTTTCAGGCGGGGCTGG
CCGGAGCGTTGCTGTTCAACCCGGACCGGGCGGCCGACCCGATGGCCATCGCGGGGGCCTTCGCGGTGCTGTTTCTGCCC
TATTCGCTGCTGGGGCCCTTCGCCGGGGCCCTAATGGACCGGTGGGATCGGCGGTGGGTGCTGGTTGGCGCCAACACCGG
CCGGCTAGCCCTGATCGCCGGGGTCGGCACGATACTCGCGGTCGGAGCCGGCGACGTGCCGCTGTTGGTCGGAGCGCTGG
TCGCCAACGGCTTGGCACGATTCGTCGCCTCGGGACTGTCGGCGGCACTGCCCCACGTGGTGCCGCGCGAACAGGTGGTC
ACGATGAACTCGGTGGCCATCGCGTCGGGGGCGGTCTCCGCGTTCCTGGGCGCCAACTTCATGCTGTTGCCTCGTTGGCT
GCTCGGCAGCGGCGACGAGGGGGCCTCCGCGATCGTCTTCCTGGTGGCGATCCCCGTATCGATCGCGTTGCTTTGGTCGC
TGCGGTTCGGCCCGCGGGTACTCGGCCCGGACGACACCGAACGCGCGATCCACGGATCTGCTGTCTACGCCGTGGTCACC
GGTTGGCTACATGGAGCGCGCACCGTGGTGCAACTTCCGACCGTCGCTGCCGGCCTGTCCGGTTTGGCAGCGCATCGGAT
GGTGGTCGGTATCAACTCACTGCTGATCTTGCTCCTGGTCCGCCACGTGACCGCCCGGGCCGTTGGGGGGTTGGGTACCG
CACTGCTGTTCTTCGCGGCCACCGGGCTGGGAGCCTTCCTGGCCAACGTCTTGACTCCGACCGCGATCCGGCGCTGGGGA
CGCTACGCCACGGCAAATGGCGCGTTGGCTGCGGCCGCCACTATCCAGGTCGCGGCCGCCGGGCTGCTGGTCCCGGTGAT
GGTGGTATGCGGCTTCCTTTTAGGTGTGGCCGGCCAGGTGGTCAAGCTGTGCGCCGATTCGGCGATGCAGATGGACGTCG
ACGACGCATTGCGCGGGCACGTGTTCGCCGTGCAGGATGCACTGTTTTGGGTCTCATACATCCTCTCGATTACCGTGGCC
GCAGCCTTGATTCCCGAGCACGGGCACGCGCCCGTATTTGTGCTGTTCGGGTCGGCGATCTACCTAGCCGGGCTGGTGGT
GCACACCATCGTCGGGCGCCGCGGCCAGCCTGTGATCGGTCGCTAG

Upstream 100 bases:

>100_bases
CCATCATCGCACCACCGTCGCATCGCCCGGGGCGAACAAGCAGGGCCGGCGAATATTTGTACTGTGGTTGGGGCGGCACG
GGGTGGACCGAACCTTGCCT

Downstream 100 bases:

>100_bases
GGTACAAACATGCCTTTCCCGACGAACTGTTACCTCAGGAGGTGGTGATGGCGGATCCTGGGCCGTTCGTGGCAGACCTG
CGTGCCGAAAGCGACGACCT

Product: integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFGDGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLP
YSLLGPFAGALMDRWDRRWVLVGANTGRLALIAGVGTILAVGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVV
TMNSVAIASGAVSAFLGANFMLLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGSAVYAVVT
GWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVTARAVGGLGTALLFFAATGLGAFLANVLTPTAIRRWG
RYATANGALAAAATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHVFAVQDALFWVSYILSITVA
AALIPEHGHAPVFVLFGSAIYLAGLVVHTIVGRRGQPVIGR

Sequences:

>Translated_441_residues
MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFGDGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLP
YSLLGPFAGALMDRWDRRWVLVGANTGRLALIAGVGTILAVGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVV
TMNSVAIASGAVSAFLGANFMLLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGSAVYAVVT
GWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVTARAVGGLGTALLFFAATGLGAFLANVLTPTAIRRWG
RYATANGALAAAATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHVFAVQDALFWVSYILSITVA
AALIPEHGHAPVFVLFGSAIYLAGLVVHTIVGRRGQPVIGR
>Mature_440_residues
PRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFGDGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPY
SLLGPFAGALMDRWDRRWVLVGANTGRLALIAGVGTILAVGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVVT
MNSVAIASGAVSAFLGANFMLLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGSAVYAVVTG
WLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVTARAVGGLGTALLFFAATGLGAFLANVLTPTAIRRWGR
YATANGALAAAATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHVFAVQDALFWVSYILSITVAA
ALIPEHGHAPVFVLFGSAIYLAGLVVHTIVGRRGQPVIGR

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y037_MYCTU (P0A5C1)

Other databases:

- EMBL:   BX842572
- EMBL:   AE000516
- PIR:   C70702
- RefSeq:   NP_214551.1
- RefSeq:   NP_334451.1
- ProteinModelPortal:   P0A5C1
- EnsemblBacteria:   EBMYCT00000001856
- EnsemblBacteria:   EBMYCT00000070138
- GeneID:   887042
- GeneID:   922611
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0042
- KEGG:   mtu:Rv0037c
- TIGR:   MT0042
- TubercuList:   Rv0037c
- GeneTree:   EBGT00050000014798
- HOGENOM:   HBG565047
- OMA:   AILFNPE
- ProtClustDB:   CLSK871747
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 45867; Mature: 45736

Theoretical pI: Translated: 11.02; Mature: 11.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17749f7c)-; HASH(0x177bf8c4)-; HASH(0x141309b4)-; HASH(0x145bfd88)-; HASH(0x1368fe48)-; HASH(0x156f6dd0)-; HASH(0x148195f8)-; HASH(0x136930bc)-; HASH(0x1783af44)-; HASH(0x16f1da34)-; HASH(0x177ea0e8)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFGDGLFQAGLAGALLFN
CCCEEEEHEEHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEC
PDRAADPMAIAGAFAVLFLPYSLLGPFAGALMDRWDRRWVLVGANTGRLALIAGVGTILA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHHHHHE
VGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVVTMNSVAIASGAVSAFLGANF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEHHHHHHHHHHHHHHHCCCH
MLLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGSAVYAVVT
HEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHH
GWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVTARAVGGLGTALLFFAA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGLGAFLANVLTPTAIRRWGRYATANGALAAAATIQVAAAGLLVPVMVVCGFLLGVAGQV
HHHHHHHHHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKLCADSAMQMDVDDALRGHVFAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAI
HHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHH
YLAGLVVHTIVGRRGQPVIGR
HHHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure 
PRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFGDGLFQAGLAGALLFN
CCEEEEHEEHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEC
PDRAADPMAIAGAFAVLFLPYSLLGPFAGALMDRWDRRWVLVGANTGRLALIAGVGTILA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHHHHHE
VGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVVTMNSVAIASGAVSAFLGANF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEHHHHHHHHHHHHHHHCCCH
MLLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGSAVYAVVT
HEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHH
GWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVTARAVGGLGTALLFFAA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGLGAFLANVLTPTAIRRWGRYATANGALAAAATIQVAAAGLLVPVMVVCGFLLGVAGQV
HHHHHHHHHHHCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKLCADSAMQMDVDDALRGHVFAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAI
HHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHH
YLAGLVVHTIVGRRGQPVIGR
HHHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036