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The map label for this gene is panD

Identifier: 148663465

GI number: 148663465

Start: 4052527

End: 4052946

Strand: Reverse

Name: panD

Synonym: MRA_3640

Alternate gene names: 148663465

Gene position: 4052946-4052527 (Counterclockwise)

Preceding gene: 148663466

Following gene: 148663464

Centisome position: 91.7

GC content: 62.14

Gene sequence:

>420_bases
ATGTTACGGACGATGCTGAAGTCGAAGATCCACCGCGCCACGGTGACCTGCGCCGACCTGCACTACGTCGGCTCGGTGAC
CATCGATGCCGACTTGATGGACGCCGCCGACCTGCTGGAAGGCGAACAGGTAACCATCGTCGATATCGACAACGGTGCTC
GACTGGTCACCTACGCGATCACCGGCGAACGCGGCAGTGGTGTGATTGGCATCAACGGTGCCGCCGCGCACTTGGTGCAT
CCGGGGGATCTGGTGATTCTGATTGCGTACGCGACGATGGACGACGCCCGGGCCCGCACATACCAGCCGCGGATCGTGTT
TGTCGACGCTTACAACAAACCGATCGACATGGGCCACGATCCGGCATTTGTGCCCGAAAACGCGGGCGAGCTGCTAGACC
CCCGGCTCGGTGTGGGATAG

Upstream 100 bases:

>100_bases
CCAGGCTGCTGGACAACATTGCGATTGAAATCGGAACTTTCGCCGGCACCGACCGCCCGGACGGATACCGGGCAATCCTC
GAATCACATTGGAGAAACTG

Downstream 100 bases:

>100_bases
CCGTGCTGCTGGCGATTGACGTCCGCAACACCCACACCGTTGTGGGCCTGCTGTCCGGAATGAAAGAGCACGCAAAGGTC
GTGCAGCAGTGGCGGATACG

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVH
PGDLVILIAYATMDDARARTYQPRIVFVDAYNKPIDMGHDPAFVPENAGELLDPRLGVG

Sequences:

>Translated_139_residues
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVH
PGDLVILIAYATMDDARARTYQPRIVFVDAYNKPIDMGHDPAFVPENAGELLDPRLGVG
>Mature_139_residues
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVH
PGDLVILIAYATMDDARARTYQPRIVFVDAYNKPIDMGHDPAFVPENAGELLDPRLGVG

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=113, Percent_Identity=50.4424778761062, Blast_Score=125, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_MYCBO (P65661)

Other databases:

- EMBL:   BX248346
- RefSeq:   NP_857270.1
- ProteinModelPortal:   P65661
- SMR:   P65661
- EnsemblBacteria:   EBMYCT00000016029
- GeneID:   1093290
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3631c
- GeneTree:   EBGT00050000017253
- HOGENOM:   HBG302821
- OMA:   LYSKIHR
- ProtClustDB:   PRK05449
- BioCyc:   MBOV233413:MB3631C-MONOMER
- BRENDA:   4.1.1.11
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 14885; Mature: 14885

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAI
CCHHHHHHHHHHEEEEEEEEEEEEEEEECCCHHCHHHHCCCCEEEEEEECCCCEEEEEEE
TGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNKPIDMGHD
ECCCCCEEEEECCCEEEEECCCCEEEEEEEECCCCCCCEECCCEEEEEECCCCCCCCCCC
PAFVPENAGELLDPRLGVG
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRTMLKSKIHRATVTCADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAI
CCHHHHHHHHHHEEEEEEEEEEEEEEEECCCHHCHHHHCCCCEEEEEEECCCCEEEEEEE
TGERGSGVIGINGAAAHLVHPGDLVILIAYATMDDARARTYQPRIVFVDAYNKPIDMGHD
ECCCCCEEEEECCCEEEEECCCCEEEEEEEECCCCCCCEECCCEEEEEECCCCCCCCCCC
PAFVPENAGELLDPRLGVG
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972