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The map label for this gene is coaX [H]

Identifier: 148663464

GI number: 148663464

Start: 4051706

End: 4052524

Strand: Reverse

Name: coaX [H]

Synonym: MRA_3639

Alternate gene names: 148663464

Gene position: 4052524-4051706 (Counterclockwise)

Preceding gene: 148663465

Following gene: 148663463

Centisome position: 91.69

GC content: 64.35

Gene sequence:

>819_bases
GTGCTGCTGGCGATTGACGTCCGCAACACCCACACCGTTGTGGGCCTGCTGTCCGGAATGAAAGAGCACGCAAAGGTCGT
GCAGCAGTGGCGGATACGCACCGAATCCGAAGTCACCGCCGACGAACTGGCACTGACGATCGACGGGCTGATCGGCGAGG
ATTCCGAGCGGCTCACCGGTACCGCCGCCTTGTCCACGGTCCCGTCCGTGCTGCACGAGGTGCGGATAATGCTCGACCAG
TACTGGCCGTCGGTGCCGCACGTGCTGATCGAGCCCGGAGTACGCACCGGGATCCCTTTGCTCGTCGACAACCCGAAGGA
AGTGGGCGCAGACCGCATCGTGAACTGTTTGGCCGCCTATGACCGGTTCCGGAAGGCCGCCATCGTCGTTGACTTTGGAT
CCTCGATCTGTGTTGATGTTGTATCGGCCAAGGGTGAATTTCTTGGCGGCGCCATCGCGCCCGGGGTGCAGGTGTCTTCC
GATGCCGCGGCGGCCCGCTCGGCGGCATTGCGCCGCGTTGAACTTGCCCGCCCACGTTCGGTGGTTGGCAAGAACACCGT
CGAATGCATGCAAGCCGGTGCGGTGTTCGGCTTCGCCGGGCTGGTAGACGGGTTGGTAGGCCGCATCCGCGAGGACGTGT
CCGGTTTCTCCGTCGACCACGATGTCGCGATCGTGGCTACCGGGCATACCGCGCCCCTGCTGCTGCCGGAATTGCACACC
GTCGACCATTACGACCAGCACCTGACCTTGCAGGGTCTGCGGCTGGTGTTCGAGCGTAACCTCGAAGTCCAGCGCGGCCG
GCTCAAGACGGCGCGCTGA

Upstream 100 bases:

>100_bases
TCGACGCTTACAACAAACCGATCGACATGGGCCACGATCCGGCATTTGTGCCCGAAAACGCGGGCGAGCTGCTAGACCCC
CGGCTCGGTGTGGGATAGCC

Downstream 100 bases:

>100_bases
CGTCGATGCCGGCATCGAGTCTGGGTACCGGGTCGCCCGCCGCCGACAGGCTCGACGCCACCCACGAGCGTCGGCGTGAG
GTCATTTAAGCTGGCACGTC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MLLAIDVRNTHTVVGLLSGMKEHAKVVQQWRIRTESEVTADELALTIDGLIGEDSERLTGTAALSTVPSVLHEVRIMLDQ
YWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAYDRFRKAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSS
DAAAARSAALRRVELARPRSVVGKNTVECMQAGAVFGFAGLVDGLVGRIREDVSGFSVDHDVAIVATGHTAPLLLPELHT
VDHYDQHLTLQGLRLVFERNLEVQRGRLKTAR

Sequences:

>Translated_272_residues
MLLAIDVRNTHTVVGLLSGMKEHAKVVQQWRIRTESEVTADELALTIDGLIGEDSERLTGTAALSTVPSVLHEVRIMLDQ
YWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAYDRFRKAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSS
DAAAARSAALRRVELARPRSVVGKNTVECMQAGAVFGFAGLVDGLVGRIREDVSGFSVDHDVAIVATGHTAPLLLPELHT
VDHYDQHLTLQGLRLVFERNLEVQRGRLKTAR
>Mature_272_residues
MLLAIDVRNTHTVVGLLSGMKEHAKVVQQWRIRTESEVTADELALTIDGLIGEDSERLTGTAALSTVPSVLHEVRIMLDQ
YWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAYDRFRKAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSS
DAAAARSAALRRVELARPRSVVGKNTVECMQAGAVFGFAGLVDGLVGRIREDVSGFSVDHDVAIVATGHTAPLLLPELHT
VDHYDQHLTLQGLRLVFERNLEVQRGRLKTAR

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 29305; Mature: 29305

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAIDVRNTHTVVGLLSGMKEHAKVVQQWRIRTESEVTADELALTIDGLIGEDSERLTG
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEECCCCCCCCHHHHH
TAALSTVPSVLHEVRIMLDQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAY
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEECCHHHHCHHHHHHHHHHH
DRFRKAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELARPRS
HHHHHEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCHH
VVGKNTVECMQAGAVFGFAGLVDGLVGRIREDVSGFSVDHDVAIVATGHTAPLLLPELHT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEECCCHHH
VDHYDQHLTLQGLRLVFERNLEVQRGRLKTAR
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCC
>Mature Secondary Structure
MLLAIDVRNTHTVVGLLSGMKEHAKVVQQWRIRTESEVTADELALTIDGLIGEDSERLTG
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEECCCCCCCCHHHHH
TAALSTVPSVLHEVRIMLDQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAY
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEECCHHHHCHHHHHHHHHHH
DRFRKAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELARPRS
HHHHHEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCHH
VVGKNTVECMQAGAVFGFAGLVDGLVGRIREDVSGFSVDHDVAIVATGHTAPLLLPELHT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEECCCHHH
VDHYDQHLTLQGLRLVFERNLEVQRGRLKTAR
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA