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The map label for this gene is cyp142

Identifier: 148663381

GI number: 148663381

Start: 3962991

End: 3964187

Strand: Reverse

Name: cyp142

Synonym: MRA_3557

Alternate gene names: 148663381

Gene position: 3964187-3962991 (Counterclockwise)

Preceding gene: 148663383

Following gene: 148663378

Centisome position: 89.69

GC content: 64.41

Gene sequence:

>1197_bases
ATGACTGAAGCTCCGGACGTGGATCTGGCCGACGGCAACTTCTACGCCAGCCGCGAGGCGCGGGCCGCGTACCGGTGGAT
GCGGGCCAACCAACCGGTGTTCCGCGATCGCAACGGCCTGGCGGCCGCGTCGACGTACCAGGCGGTGATCGACGCCGAAC
GTCAACCCGAGCTGTTCTCCAACGCCGGCGGCATCCGCCCCGACCAGCCCGCCCTGCCGATGATGATCGACATGGACGAT
CCCGCACATCTGTTGCGGCGCAAGCTGGTTAACGCCGGCTTCACCCGCAAGCGGGTGAAGGACAAGGAGGCGTCGATTGC
CGCGCTGTGTGACACCCTGATCGACGCCGTGTGCGAACGCGGCGAGTGTGACTTCGTGCGGGACCTGGCCGCGCCGCTAC
CGATGGCGGTGATCGGCGACATGCTCGGGGTGCGTCCAGAGCAGCGGGACATGTTCTTGCGGTGGTCCGACGATCTGGTG
ACATTCCTCAGTTCGCATGTGTCTCAAGAGGATTTCCAGATCACCATGGACGCCTTCGCGGCCTACAACGACTTCACCCG
GGCCACCATTGCGGCACGGCGAGCGGACCCCACCGACGACCTGGTCAGCGTGCTGGTGAGTTCCGAAGTTGACGGCGAGC
GGCTAAGCGACGACGAGCTGGTCATGGAGACGCTGCTGATCCTGATCGGCGGCGACGAGACCACGCGGCATACCTTGAGC
GGTGGTACCGAGCAGCTGCTGCGCAACCGTGACCAGTGGGACCTGCTGCAGCGCGACCCGTCGTTGCTGCCCGGGGCCAT
CGAGGAGATGCTACGTTGGACCGCCCCGGTAAAGAACATGTGCCGGGTGTTGACCGCGGATACCGAGTTTCACGGCACGG
CGTTGTGTGCCGGCGAGAAGATGATGCTGCTCTTCGAGTCGGCGAACTTCGACGAGGCGGTTTTCTGTGAACCGGAAAAG
TTTGATGTTCAGCGAAATCCAAACAGCCACTTGGCGTTTGGCTTCGGCACGCATTTCTGCCTGGGCAATCAGCTGGCCCG
GTTGGAGCTGTCGTTGATGACGGAACGGGTGTTGCGGCGGCTACCCGACCTGCGGTTGGTCGCCGATGACTCCGTGTTGC
CGCTGCGGCCGGCGAACTTTGTCAGCGGCCTGGAATCCATGCCGGTGGTGTTCACGCCGAGCCCGCCGCTGGGCTGA

Upstream 100 bases:

>100_bases
CAGGTTGGCGGTGCGAATGCGCACCGGCATGGTGAGCACCGTGCCGGCGATGGTGTGTTGCGAGACGGGCATATCGCCCA
CTGTAGTGCGGAGGATCGCG

Downstream 100 bases:

>100_bases
GCCACGCCGAACGTGAACTGAGGGCGGAATATCGGCCGAATCTCCGCCGTGAGTTCACGTTCGGCGCTGCCAGGCCGCTG
ACACCCGCCAGATGATGCCA

Product: putative cytochrome p450 monooxygenase 142 CYP142

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTEAPDVDLADGNFYASREARAAYRWMRANQPVFRDRNGLAAASTYQAVIDAERQPELFSNAGGIRPDQPALPMMIDMDD
PAHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCERGECDFVRDLAAPLPMAVIGDMLGVRPEQRDMFLRWSDDLV
TFLSSHVSQEDFQITMDAFAAYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLS
GGTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEKMMLLFESANFDEAVFCEPEK
FDVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESMPVVFTPSPPLG

Sequences:

>Translated_398_residues
MTEAPDVDLADGNFYASREARAAYRWMRANQPVFRDRNGLAAASTYQAVIDAERQPELFSNAGGIRPDQPALPMMIDMDD
PAHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCERGECDFVRDLAAPLPMAVIGDMLGVRPEQRDMFLRWSDDLV
TFLSSHVSQEDFQITMDAFAAYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLS
GGTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEKMMLLFESANFDEAVFCEPEK
FDVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESMPVVFTPSPPLG
>Mature_397_residues
TEAPDVDLADGNFYASREARAAYRWMRANQPVFRDRNGLAAASTYQAVIDAERQPELFSNAGGIRPDQPALPMMIDMDDP
AHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCERGECDFVRDLAAPLPMAVIGDMLGVRPEQRDMFLRWSDDLVT
FLSSHVSQEDFQITMDAFAAYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLSG
GTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEKMMLLFESANFDEAVFCEPEKF
DVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESMPVVFTPSPPLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CP142_MYCTU (O53563)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   H70807
- RefSeq:   NP_218035.1
- RefSeq:   NP_338165.1
- PDB:   2XKR
- PDBsum:   2XKR
- ProteinModelPortal:   O53563
- SMR:   O53563
- EnsemblBacteria:   EBMYCT00000000037
- EnsemblBacteria:   EBMYCT00000072538
- GeneID:   888282
- GeneID:   926584
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3619
- KEGG:   mtu:Rv3518c
- TIGR:   MT3619
- TubercuList:   Rv3518c
- GeneTree:   EBGT00050000015568
- HOGENOM:   HBG695262
- OMA:   VTIDAFA
- ProtClustDB:   CLSK792538
- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972
- Gene3D:   G3DSA:1.10.630.10
- PANTHER:   PTHR19383
- PRINTS:   PR00359
- PRINTS:   PR00385

Pfam domain/function: PF00067 p450; SSF48264 Cytochrome_P450

EC number: NA

Molecular weight: Translated: 44399; Mature: 44268

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAPDVDLADGNFYASREARAAYRWMRANQPVFRDRNGLAAASTYQAVIDAERQPELFS
CCCCCCCCCCCCCEEECHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHCCCCCCHHHH
NAGGIRPDQPALPMMIDMDDPAHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCER
CCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GECDFVRDLAAPLPMAVIGDMLGVRPEQRDMFLRWSDDLVTFLSSHVSQEDFQITMDAFA
CCCHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHEEHHHHHH
AYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLS
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHHHHHHC
GGTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEK
CCHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCE
MMLLFESANFDEAVFCEPEKFDVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRR
EEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHHHH
LPDLRLVADDSVLPLRPANFVSGLESMPVVFTPSPPLG
CCCCEEEECCCCCCCCCHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure 
TEAPDVDLADGNFYASREARAAYRWMRANQPVFRDRNGLAAASTYQAVIDAERQPELFS
CCCCCCCCCCCCEEECHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHCCCCCCHHHH
NAGGIRPDQPALPMMIDMDDPAHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCER
CCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GECDFVRDLAAPLPMAVIGDMLGVRPEQRDMFLRWSDDLVTFLSSHVSQEDFQITMDAFA
CCCHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHEEHHHHHH
AYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLS
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHHHHHHC
GGTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEK
CCHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCE
MMLLFESANFDEAVFCEPEKFDVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRR
EEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHHHH
LPDLRLVADDSVLPLRPANFVSGLESMPVVFTPSPPLG
CCCCEEEECCCCCCCCCHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036