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The map label for this gene is fabG [H]

Identifier: 148663366

GI number: 148663366

Start: 3929764

End: 3930717

Strand: Reverse

Name: fabG [H]

Synonym: MRA_3542

Alternate gene names: 148663366

Gene position: 3930717-3929764 (Counterclockwise)

Preceding gene: 148663367

Following gene: 148663365

Centisome position: 88.93

GC content: 67.4

Gene sequence:

>954_bases
TTGAAATTGACTGAGTCCAATCGCTCGCCGCGTACCACGAACACGACCGATCTGTCCGGAAAGGTGGCGGTGGTCACCGG
CGCGGCCGCGGGTTTGGGTCGGGCCGAAGCGCTCGGCCTGGCCCGGTTGGGCGCCACCGTCGTCGTCAACGATGTTGCTT
CCGCCCTGGATGCTTCCGACGTCGTCGACGAGATCGGCGCCGCCGCTGCCGATGCTGGTGCTAAGGCCGTCGCGGTAGCC
GGTGATATCAGCCAGCGCGCGACGGCCGACGAACTGCTCGCCAGCGCCGTCGGGCTGGGCGGACTGGACATCGTGGTGAA
CAATGCCGGCATCACCCGCGACCGGATGCTGTTCAACATGTCCGACGAGGAGTGGGACGCCGTGATCGCGGTGCACCTGC
GCGGCCATTTTCTGCTCACCCGCAACGCCGCTGCCTACTGGCGGGACAAAGCCAAGGATGCCGAAGGGGGATCGGTCTTC
GGCCGGCTCGTCAACACCTCGTCGGAGGCGGGTCTGGTGGGCCCGGTGGGGCAGGCGAATTACGCCGCCGCCAAGGCTGG
CATCACCGCGCTAACCCTGTCGGCGGCGCGGGCGCTCGGGCGCTACGGCGTTTGCGCCAATGTGATTTGTCCGCGGGCGC
GCACCGCGATGACGGCCGATGTCTTCGGCGCCGCACCCGATGTCGAAGCGGGCCAGATCGACCCGCTGTCGCCGCAGCAT
GTGGTAAGCCTGGTCCAGTTTCTGGCGTCCCCGGCTGCCGCGGAAGTCAACGGTCAGGTGTTCATCGTCTACGGTCCGCA
GGTGACGCTGGTGTCACCGCCGCACATGGAGCGCCGGTTCAGCGCGGACGGCACGTCCTGGGATCCCACCGAGCTCACCG
CGACGCTGCGGGACTACTTTGCTGGTCGGGATCCGGAACAGAGCTTTTCGGCGACCGATCTGATGCGTCAGTGA

Upstream 100 bases:

>100_bases
CCCGGTTGATCAGGAGGATCTGGCCGAGCAGGCCATCGCGGAATGCCCGCGTGCGGCGTTGTCGCGTGGTGAGTAGGACG
GAACTAGAGGTATTCATAAA

Downstream 100 bases:

>100_bases
CCCGTGGATATAGGCGGCCGATTATTGGAATCGGTGTCCGAATCACCACGCCAACATAGGGCTTAACCAGCGAAATTGAC
CCAGTTGATCCGGTGTGCGG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALDASDVVDEIGAAAADAGAKAVAVA
GDISQRATADELLASAVGLGGLDIVVNNAGITRDRMLFNMSDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAEGGSVF
GRLVNTSSEAGLVGPVGQANYAAAKAGITALTLSAARALGRYGVCANVICPRARTAMTADVFGAAPDVEAGQIDPLSPQH
VVSLVQFLASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLRDYFAGRDPEQSFSATDLMRQ

Sequences:

>Translated_317_residues
MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALDASDVVDEIGAAAADAGAKAVAVA
GDISQRATADELLASAVGLGGLDIVVNNAGITRDRMLFNMSDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAEGGSVF
GRLVNTSSEAGLVGPVGQANYAAAKAGITALTLSAARALGRYGVCANVICPRARTAMTADVFGAAPDVEAGQIDPLSPQH
VVSLVQFLASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLRDYFAGRDPEQSFSATDLMRQ
>Mature_317_residues
MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALDASDVVDEIGAAAADAGAKAVAVA
GDISQRATADELLASAVGLGGLDIVVNNAGITRDRMLFNMSDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAEGGSVF
GRLVNTSSEAGLVGPVGQANYAAAKAGITALTLSAARALGRYGVCANVICPRARTAMTADVFGAAPDVEAGQIDPLSPQH
VVSLVQFLASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLRDYFAGRDPEQSFSATDLMRQ

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=255, Percent_Identity=39.2156862745098, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=37.5968992248062, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI4758504, Length=201, Percent_Identity=34.8258706467662, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=28.3524904214559, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI83715985, Length=194, Percent_Identity=35.0515463917526, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI40807363, Length=236, Percent_Identity=28.3898305084746, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI31542939, Length=203, Percent_Identity=32.512315270936, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=29.6442687747036, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787335, Length=265, Percent_Identity=34.3396226415094, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=28.0769230769231, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790717, Length=260, Percent_Identity=28.0769230769231, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87082100, Length=229, Percent_Identity=31.0043668122271, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=26.3779527559055, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789057, Length=271, Percent_Identity=30.2583025830258, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786812, Length=267, Percent_Identity=29.5880149812734, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=29.9212598425197, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=31.1284046692607, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI2367175, Length=196, Percent_Identity=32.1428571428571, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=29.1666666666667, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=249, Percent_Identity=36.144578313253, Blast_Score=144, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=33.0739299610895, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17564282, Length=206, Percent_Identity=31.5533980582524, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=268, Percent_Identity=31.7164179104478, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=250, Percent_Identity=28.8, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=251, Percent_Identity=28.6852589641434, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=199, Percent_Identity=33.6683417085427, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=225, Percent_Identity=31.5555555555556, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=216, Percent_Identity=32.4074074074074, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=272, Percent_Identity=27.9411764705882, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=200, Percent_Identity=33, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=205, Percent_Identity=30.7317073170732, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=267, Percent_Identity=26.2172284644195, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=281, Percent_Identity=27.0462633451957, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=26.4591439688716, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=209, Percent_Identity=29.6650717703349, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=250, Percent_Identity=36.4, Blast_Score=139, Evalue=5e-34,
Organism=Drosophila melanogaster, GI18859837, Length=247, Percent_Identity=40.080971659919, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=37.0656370656371, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI17737361, Length=201, Percent_Identity=32.8358208955224, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI23397609, Length=265, Percent_Identity=30.9433962264151, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24644339, Length=218, Percent_Identity=28.4403669724771, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355631, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 32753; Mature: 32753

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALDASD
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHH
VVDEIGAAAADAGAKAVAVAGDISQRATADELLASAVGLGGLDIVVNNAGITRDRMLFNM
HHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHEEECC
SDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAEGGSVFGRLVNTSSEAGLVGPVGQAN
CCCCCCEEEEEEECCEEEEECCCHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC
YAAAKAGITALTLSAARALGRYGVCANVICPRARTAMTADVFGAAPDVEAGQIDPLSPQH
HHHHHHCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHH
VVSLVQFLASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLRDYF
HHHHHHHHCCCCCEECCCEEEEEECCEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHH
AGRDPEQSFSATDLMRQ
CCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALDASD
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHH
VVDEIGAAAADAGAKAVAVAGDISQRATADELLASAVGLGGLDIVVNNAGITRDRMLFNM
HHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHEEECC
SDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAEGGSVFGRLVNTSSEAGLVGPVGQAN
CCCCCCEEEEEEECCEEEEECCCHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC
YAAAKAGITALTLSAARALGRYGVCANVICPRARTAMTADVFGAAPDVEAGQIDPLSPQH
HHHHHHCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHH
VVSLVQFLASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLRDYF
HHHHHHHHCCCCCEECCCEEEEEECCEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHH
AGRDPEQSFSATDLMRQ
CCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]