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The map label for this gene is yjeF [C]

Identifier: 148663298

GI number: 148663298

Start: 3860470

End: 3861891

Strand: Reverse

Name: yjeF [C]

Synonym: MRA_3474

Alternate gene names: 148663298

Gene position: 3861891-3860470 (Counterclockwise)

Preceding gene: 148663299

Following gene: 148663297

Centisome position: 87.37

GC content: 74.75

Gene sequence:

>1422_bases
ATGCGCCACTACTACTCTGTCGACACCATCCGCGCGGCTGAGGCGCCCCTGTTGGCCAGCCTGCCCGACGGTGCGCTGAT
GCGACGCGCGGCCTTCGGGCTGGCCACCGAGATCGGCCGTGAGTTGACCGCTCGCACGGGTGGGGTGGTCGGCCGCCGGG
TGTGCGCGGTCGTCGGATCCGGCGACAACGGTGGCGACGCGCTGTGGGCGGCGACGTTCCTGCGACGCCGCGGCGCCGCC
GCCGACGCGGTGCTGCTCAACCCGGACCGCACGCATCGCAAGGCGCTGGCGGCGTTCACCAAATCCGGGGGTCGCCTCGT
CGAGAGTGTCTCGGCGGCGACCGATCTCGTCATCGACGGGGTGGTCGGCATCTCCGGCTCGGGGCCGCTGCGACCGGCGG
CCGCGCAGGTGTTCGCCGCGGTTCAGGCCGCCGCCATACCGGTGGTCGCCGTCGACATCCCCAGCGGCATCGATGTGGCG
ACCGGGGCGATCACCGGCCCCGCCGTGCACGCCGCGCTGACCGTCACCTTTGGCGGGCTCAAACCGGTGCACGCGCTGGC
CGACTGCGGCCGCGTCGTCCTTGTCGATATCGGGCTGGACCTGGCGCACACCGACGTGTTGGGTTTCGAGGCTACCGACG
TGGCCGCGCGCTGGCCGGTGCCCGGTCCCCGCGACGACAAATACACCCAGGGCGTGACCGGCGTGCTGGCCGGGTCGTCG
ACGTATCCGGGTGCGGCCGTGCTGTGCACCGGGGCGGCCGTCGCCGCCACCTCCGGCATGGTCCGCTACGCCGGGACCGC
CCATGCGGAAGTCCTCGCGCACTGGCCGGAGGTCATCGCCTCGCCCACCCCGGCGGCGGCCGGGCGGGTGCAGGCCTGGG
TCGTCGGGCCGGGCCTGGGCACCGACGAAGCCGGGGCCGCCGCGTTGTGGTTCGCGCTGGACACCGACCTGCCGGTGTTG
GTCGACGCCGACGGGCTGACCATGCTGGCGGACCACCCCGATCTGGTGGCGGGCCGCAACGCCCCGACGGTCTTGACGCC
GCACGCCGGTGAGTTCGCCCGGCTGGCCGGGGCGCCGCCCGGTGACGACCGCGTGGGGGCCTGCCGCCAGCTGGCCGACG
CGCTGGGCGCCACCGTGCTGCTCAAGGGCAATGTCACCGTCATCGCCGATCCCGGCGGCCCGGTCTATCTCAATCCGGCC
GGCCAGTCCTGGGCGGCCACCGCCGGGTCCGGTGACGTGCTGTCCGGGATGATCGGTGCGCTGCTGGCGTCGGGATTGCC
GTCTGGGGAGGCGGCCGCGGCCGCGGCGTTCGTGCACGCCCGGGCATCGGCGGCCGCGGCCGCCGATCCCGGCCCCGGCG
ATGCGCCCACGTCGGCGTCGCGCATCAGCGGCCACATTCGGGCCGCTCTGGCTGCCCTGTAG

Upstream 100 bases:

>100_bases
TTCTATCCGATGGCCCGGGAACGCGACGGTCGGCTGTGGAATCCGGCCAGAATCAAAAGTCTGCTGCACAGGCGCGGCAC
CCGAGGACGGCGGGCCTGAG

Downstream 100 bases:

>100_bases
TCCTGCCAGTCCGCAACAAGCCCGGAAAGGATCCGCCGTGTCTCGCAGTCACCCGTCCGTGCCCGCGCATTCGATCGCTC
CGGCCTACACCGGTCGGATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MRHYYSVDTIRAAEAPLLASLPDGALMRRAAFGLATEIGRELTARTGGVVGRRVCAVVGSGDNGGDALWAATFLRRRGAA
ADAVLLNPDRTHRKALAAFTKSGGRLVESVSAATDLVIDGVVGISGSGPLRPAAAQVFAAVQAAAIPVVAVDIPSGIDVA
TGAITGPAVHAALTVTFGGLKPVHALADCGRVVLVDIGLDLAHTDVLGFEATDVAARWPVPGPRDDKYTQGVTGVLAGSS
TYPGAAVLCTGAAVAATSGMVRYAGTAHAEVLAHWPEVIASPTPAAAGRVQAWVVGPGLGTDEAGAAALWFALDTDLPVL
VDADGLTMLADHPDLVAGRNAPTVLTPHAGEFARLAGAPPGDDRVGACRQLADALGATVLLKGNVTVIADPGGPVYLNPA
GQSWAATAGSGDVLSGMIGALLASGLPSGEAAAAAAFVHARASAAAAADPGPGDAPTSASRISGHIRAALAAL

Sequences:

>Translated_473_residues
MRHYYSVDTIRAAEAPLLASLPDGALMRRAAFGLATEIGRELTARTGGVVGRRVCAVVGSGDNGGDALWAATFLRRRGAA
ADAVLLNPDRTHRKALAAFTKSGGRLVESVSAATDLVIDGVVGISGSGPLRPAAAQVFAAVQAAAIPVVAVDIPSGIDVA
TGAITGPAVHAALTVTFGGLKPVHALADCGRVVLVDIGLDLAHTDVLGFEATDVAARWPVPGPRDDKYTQGVTGVLAGSS
TYPGAAVLCTGAAVAATSGMVRYAGTAHAEVLAHWPEVIASPTPAAAGRVQAWVVGPGLGTDEAGAAALWFALDTDLPVL
VDADGLTMLADHPDLVAGRNAPTVLTPHAGEFARLAGAPPGDDRVGACRQLADALGATVLLKGNVTVIADPGGPVYLNPA
GQSWAATAGSGDVLSGMIGALLASGLPSGEAAAAAAFVHARASAAAAADPGPGDAPTSASRISGHIRAALAAL
>Mature_473_residues
MRHYYSVDTIRAAEAPLLASLPDGALMRRAAFGLATEIGRELTARTGGVVGRRVCAVVGSGDNGGDALWAATFLRRRGAA
ADAVLLNPDRTHRKALAAFTKSGGRLVESVSAATDLVIDGVVGISGSGPLRPAAAQVFAAVQAAAIPVVAVDIPSGIDVA
TGAITGPAVHAALTVTFGGLKPVHALADCGRVVLVDIGLDLAHTDVLGFEATDVAARWPVPGPRDDKYTQGVTGVLAGSS
TYPGAAVLCTGAAVAATSGMVRYAGTAHAEVLAHWPEVIASPTPAAAGRVQAWVVGPGLGTDEAGAAALWFALDTDLPVL
VDADGLTMLADHPDLVAGRNAPTVLTPHAGEFARLAGAPPGDDRVGACRQLADALGATVLLKGNVTVIADPGGPVYLNPA
GQSWAATAGSGDVLSGMIGALLASGLPSGEAAAAAAFVHARASAAAAADPGPGDAPTSASRISGHIRAALAAL

Specific function: Unknown

COG id: COG0063

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YjeF N-terminal domain

Homologues:

Organism=Homo sapiens, GI119709830, Length=225, Percent_Identity=34.2222222222222, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI1790609, Length=428, Percent_Identity=31.5420560747664, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17554656, Length=218, Percent_Identity=27.9816513761468, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357759, Length=259, Percent_Identity=32.8185328185328, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3433_MYCTU (O06250)

Other databases:

- EMBL:   BX842583
- EMBL:   AE000516
- PIR:   G70975
- RefSeq:   NP_217950.1
- RefSeq:   NP_338065.1
- ProteinModelPortal:   O06250
- SMR:   O06250
- EnsemblBacteria:   EBMYCT00000000219
- EnsemblBacteria:   EBMYCT00000070940
- GeneID:   887571
- GeneID:   922999
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3539
- KEGG:   mtu:Rv3433c
- TIGR:   MT3539
- TubercuList:   Rv3433c
- GeneTree:   EBGT00050000017099
- HOGENOM:   HBG662407
- OMA:   RGMLASD
- ProtClustDB:   CLSK872182
- InterPro:   IPR017953
- InterPro:   IPR000631
- InterPro:   IPR004443
- TIGRFAMs:   TIGR00196
- TIGRFAMs:   TIGR00197

Pfam domain/function: PF01256 Carb_kinase; PF03853 YjeF_N; SSF64153 YjeF_N

EC number: NA

Molecular weight: Translated: 46858; Mature: 46858

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS01049 YJEF_C_1; PS01050 YJEF_C_2; PS51383 YJEF_C_3; PS51385 YJEF_N

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHYYSVDTIRAAEAPLLASLPDGALMRRAAFGLATEIGRELTARTGGVVGRRVCAVVGS
CCEEEECCCCHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCEEEEEEEEC
GDNGGDALWAATFLRRRGAAADAVLLNPDRTHRKALAAFTKSGGRLVESVSAATDLVIDG
CCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEC
VVGISGSGPLRPAAAQVFAAVQAAAIPVVAVDIPSGIDVATGAITGPAVHAALTVTFGGL
EEECCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCEEEEEEEEECCC
KPVHALADCGRVVLVDIGLDLAHTDVLGFEATDVAARWPVPGPRDDKYTQGVTGVLAGSS
CHHHHHHHCCCEEEEEECCCEECCEEECCCCCCCEEECCCCCCCCCCHHCCCEEEEECCC
TYPGAAVLCTGAAVAATSGMVRYAGTAHAEVLAHWPEVIASPTPAAAGRVQAWVVGPGLG
CCCCCEEEECCHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
TDEAGAAALWFALDTDLPVLVDADGLTMLADHPDLVAGRNAPTVLTPHAGEFARLAGAPP
CCCCCCEEEEEEECCCCCEEEECCCCEEEECCCCEEECCCCCEEECCCCCCHHHHCCCCC
GDDRVGACRQLADALGATVLLKGNVTVIADPGGPVYLNPAGQSWAATAGSGDVLSGMIGA
CCCHHHHHHHHHHHCCCEEEEECCEEEEECCCCCEEECCCCCCCEECCCCCHHHHHHHHH
LLASGLPSGEAAAAAAFVHARASAAAAADPGPGDAPTSASRISGHIRAALAAL
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRHYYSVDTIRAAEAPLLASLPDGALMRRAAFGLATEIGRELTARTGGVVGRRVCAVVGS
CCEEEECCCCHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHCEEEEEEEEC
GDNGGDALWAATFLRRRGAAADAVLLNPDRTHRKALAAFTKSGGRLVESVSAATDLVIDG
CCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEC
VVGISGSGPLRPAAAQVFAAVQAAAIPVVAVDIPSGIDVATGAITGPAVHAALTVTFGGL
EEECCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCEEEEEEEEECCC
KPVHALADCGRVVLVDIGLDLAHTDVLGFEATDVAARWPVPGPRDDKYTQGVTGVLAGSS
CHHHHHHHCCCEEEEEECCCEECCEEECCCCCCCEEECCCCCCCCCCHHCCCEEEEECCC
TYPGAAVLCTGAAVAATSGMVRYAGTAHAEVLAHWPEVIASPTPAAAGRVQAWVVGPGLG
CCCCCEEEECCHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
TDEAGAAALWFALDTDLPVLVDADGLTMLADHPDLVAGRNAPTVLTPHAGEFARLAGAPP
CCCCCCEEEEEEECCCCCEEEECCCCEEEECCCCEEECCCCCEEECCCCCCHHHHCCCCC
GDDRVGACRQLADALGATVLLKGNVTVIADPGGPVYLNPAGQSWAATAGSGDVLSGMIGA
CCCHHHHHHHHHHHCCCEEEEECCEEEEECCCCCEEECCCCCCCEECCCCCHHHHHHHHH
LLASGLPSGEAAAAAAFVHARASAAAAADPGPGDAPTSASRISGHIRAALAAL
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036