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The map label for this gene is 148663292

Identifier: 148663292

GI number: 148663292

Start: 3853416

End: 3854648

Strand: Reverse

Name: 148663292

Synonym: MRA_3468

Alternate gene names: NA

Gene position: 3854648-3853416 (Counterclockwise)

Preceding gene: 148663294

Following gene: 148663291

Centisome position: 87.21

GC content: 66.5

Gene sequence:

>1233_bases
GTGGCCACGATAGCCCAACGGCTGCGTGACGACCACGGGGTGGCGGCGTCGGAGTCGTCGGTGAGGCGTTGGATCGCAAC
GCATTTCGCCGAGGAGGTGGCCCGCGAGAGAGTCACGGTGCCGCGCGGACCGGTCGATGCGGGTAGTGAGGCGCAGATCG
ATTACGGGCGGCTGGGCATGTGGTTCGACCCGGCCACCGCGCGCCGGGTCGCGGTGTGGGCGTTCGTGATGGTGCTGGCG
TTCTCCCGACACCTGTTCGTGCGTCCGGTCATCCGGATGGACCAAACCGCTTGGTGTGCTTGCCATGTCGCCGCATTCGA
ATTCTTCGACGGGGTGCCGGCGCGGCTAGTGTGTGACAACCTCAGGACCGGGGTGGACAAGCCCGACCTGTACGACCCGC
AGATCAACCGCTCCTACGCCGAGCTGGCCAGCCACTACGCCACGCTGGTCGACCCGGCCCGCGCCAGAAAACCCAAAGAT
AAACCCCGCGTGGAGCGGCCGATGACCTATGTGCGGGACTCGTTTTGGAAAGGCCGCGAGTTCGATTCGCTGGCCCAGAT
GCAGCAGGCGGCGGTCACCTGGAGCACCGAAGTGGCCGGGCTTCGGTACTTACGTGCCTTGGAGGGCGCCCAACCCCTGC
GGATGTTCGAAGCTGTGGAGCAACAAGCGTTGATCGCATTGCCGCCCAGGGCATTTGAACTCACCAGCTGGTCGATCGGC
ACCGTCGGGGTGGACACGCACCTCAAAGTTGGCAAGGCACTCTATTCCGTGCCGTGGCGGCTGATCGGGCAACGCCTGCA
CGCGCGCACCGCCGGTGATGTGGTGCAGATCTTCGCCGGCAACGATGTGGTGGCCACCCATGTGCGCCGACCCAGCGGGC
GCTCCACCGACTTCTCCCACTACCCACCGGAGAAGATCGCCTTCCACATGCGCACCCCGACCTGGTGTCGACACACCGCC
GAACTGGTCGGCCCAGCCAGCCAGCAAGTGATCGCCGAATTCATGCGCGACAACGCCATCCACCACCTACGGTCGGCCCA
AGGCGTGCTCGGGCTACGCGACAAACACGGCTGCGACCGGCTGGAGGCCGCCTGCGCCCGCGCCATCGAGGTCGGCGACC
CGAGCTATCGCACCATCAAGGGCATCCTTGTTGCCGGCACCGAACACGCCGCCAACGAGCCGACCACCAGTAGTCCGGCA
AGCACCGCTGGGGGCGTTCCTGCGCGGCCCTGA

Upstream 100 bases:

>100_bases
GGGTGGTTTCCTGAATGATCCGGCGGCGCGGGCGTCGACGTGGCCGCTGATCGCGCCGCATCATGATCGGATCAAGGACT
GGCTGGATGCCGATGTCACG

Downstream 100 bases:

>100_bases
ACAGTTCGGCACCGACACACCCCGTCGCCTGATCTCACAGCGGAATCCCGAACCATCCCGACACAATCCACATCGCTATT
CTCAAGGAGAAGCATCCATG

Product: ISMt2 transposase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MATIAQRLRDDHGVAASESSVRRWIATHFAEEVARERVTVPRGPVDAGSEAQIDYGRLGMWFDPATARRVAVWAFVMVLA
FSRHLFVRPVIRMDQTAWCACHVAAFEFFDGVPARLVCDNLRTGVDKPDLYDPQINRSYAELASHYATLVDPARARKPKD
KPRVERPMTYVRDSFWKGREFDSLAQMQQAAVTWSTEVAGLRYLRALEGAQPLRMFEAVEQQALIALPPRAFELTSWSIG
TVGVDTHLKVGKALYSVPWRLIGQRLHARTAGDVVQIFAGNDVVATHVRRPSGRSTDFSHYPPEKIAFHMRTPTWCRHTA
ELVGPASQQVIAEFMRDNAIHHLRSAQGVLGLRDKHGCDRLEAACARAIEVGDPSYRTIKGILVAGTEHAANEPTTSSPA
STAGGVPARP

Sequences:

>Translated_410_residues
MATIAQRLRDDHGVAASESSVRRWIATHFAEEVARERVTVPRGPVDAGSEAQIDYGRLGMWFDPATARRVAVWAFVMVLA
FSRHLFVRPVIRMDQTAWCACHVAAFEFFDGVPARLVCDNLRTGVDKPDLYDPQINRSYAELASHYATLVDPARARKPKD
KPRVERPMTYVRDSFWKGREFDSLAQMQQAAVTWSTEVAGLRYLRALEGAQPLRMFEAVEQQALIALPPRAFELTSWSIG
TVGVDTHLKVGKALYSVPWRLIGQRLHARTAGDVVQIFAGNDVVATHVRRPSGRSTDFSHYPPEKIAFHMRTPTWCRHTA
ELVGPASQQVIAEFMRDNAIHHLRSAQGVLGLRDKHGCDRLEAACARAIEVGDPSYRTIKGILVAGTEHAANEPTTSSPA
STAGGVPARP
>Mature_409_residues
ATIAQRLRDDHGVAASESSVRRWIATHFAEEVARERVTVPRGPVDAGSEAQIDYGRLGMWFDPATARRVAVWAFVMVLAF
SRHLFVRPVIRMDQTAWCACHVAAFEFFDGVPARLVCDNLRTGVDKPDLYDPQINRSYAELASHYATLVDPARARKPKDK
PRVERPMTYVRDSFWKGREFDSLAQMQQAAVTWSTEVAGLRYLRALEGAQPLRMFEAVEQQALIALPPRAFELTSWSIGT
VGVDTHLKVGKALYSVPWRLIGQRLHARTAGDVVQIFAGNDVVATHVRRPSGRSTDFSHYPPEKIAFHMRTPTWCRHTAE
LVGPASQQVIAEFMRDNAIHHLRSAQGVLGLRDKHGCDRLEAACARAIEVGDPSYRTIKGILVAGTEHAANEPTTSSPAS
TAGGVPARP

Specific function: Unknown

COG id: COG4584

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3428_MYCTU (Q50700)

Other databases:

- EMBL:   BX842583
- PIR:   A70739
- RefSeq:   NP_217945.1
- EnsemblBacteria:   EBMYCT00000002975
- GeneID:   887621
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv3428c
- TubercuList:   Rv3428c
- GeneTree:   EBGT00050000018031
- HOGENOM:   HBG571081
- OMA:   ASEHGIV
- ProtClustDB:   CLSK792486
- InterPro:   IPR001584
- InterPro:   IPR012337

Pfam domain/function: PF00665 rve; SSF53098 RNaseH_fold

EC number: NA

Molecular weight: Translated: 45494; Mature: 45363

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIAQRLRDDHGVAASESSVRRWIATHFAEEVARERVTVPRGPVDAGSEAQIDYGRLGM
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCE
WFDPATARRVAVWAFVMVLAFSRHLFVRPVIRMDQTAWCACHVAAFEFFDGVPARLVCDN
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LRTGVDKPDLYDPQINRSYAELASHYATLVDPARARKPKDKPRVERPMTYVRDSFWKGRE
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHCCCCC
FDSLAQMQQAAVTWSTEVAGLRYLRALEGAQPLRMFEAVEQQALIALPPRAFELTSWSIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEECCCCCEEECCCCCC
TVGVDTHLKVGKALYSVPWRLIGQRLHARTAGDVVQIFAGNDVVATHVRRPSGRSTDFSH
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCCCCCC
YPPEKIAFHMRTPTWCRHTAELVGPASQQVIAEFMRDNAIHHLRSAQGVLGLRDKHGCDR
CCHHHEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LEAACARAIEVGDPSYRTIKGILVAGTEHAANEPTTSSPASTAGGVPARP
HHHHHHHHHHCCCCCHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATIAQRLRDDHGVAASESSVRRWIATHFAEEVARERVTVPRGPVDAGSEAQIDYGRLGM
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCE
WFDPATARRVAVWAFVMVLAFSRHLFVRPVIRMDQTAWCACHVAAFEFFDGVPARLVCDN
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LRTGVDKPDLYDPQINRSYAELASHYATLVDPARARKPKDKPRVERPMTYVRDSFWKGRE
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHCCCCC
FDSLAQMQQAAVTWSTEVAGLRYLRALEGAQPLRMFEAVEQQALIALPPRAFELTSWSIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEECCCCCEEECCCCCC
TVGVDTHLKVGKALYSVPWRLIGQRLHARTAGDVVQIFAGNDVVATHVRRPSGRSTDFSH
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCCCCCC
YPPEKIAFHMRTPTWCRHTAELVGPASQQVIAEFMRDNAIHHLRSAQGVLGLRDKHGCDR
CCHHHEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LEAACARAIEVGDPSYRTIKGILVAGTEHAANEPTTSSPASTAGGVPARP
HHHHHHHHHHCCCCCHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230