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The map label for this gene is cstA

Identifier: 148662916

GI number: 148662916

Start: 3439399

End: 3441675

Strand: Direct

Name: cstA

Synonym: MRA_3095

Alternate gene names: 148662916

Gene position: 3439399-3441675 (Clockwise)

Preceding gene: 148662915

Following gene: 148662917

Centisome position: 77.81

GC content: 64.38

Gene sequence:

>2277_bases
GTGGCAGCGCCGACCCCGTCGAATCGGATCGAAGAACGCTCCGGACACGCCAGCTGCGTCCGCGCCGATGCCGACCTGCC
ACCCGTGGCCATCCTCGGTCGCTCCCCCATCACGCTTCGGCACAAGATCTTCTTCGTGGCCGTTGCCGTGATCGGCGCTC
TCGCCTGGACCGTCGTCGCGTTCTTCCGCAACGAGCCGGTCAACGCGGTCTGGATCGTGGTCGCAGCGGGCTGCACCTAC
ATCATCGGGTTCCGGTTTTATGCGCGGCTGATCGAAATGAAAGTCGTCCGTCCCCGCGACGATCACGCCACCCCGGCCGA
AATCCTCGACGACGGCACCGACTACGTGCCCACCGACCGGCGGGTGGTATTCGGACACCACTTCGCCGCCATCGCCGGTG
CCGGGCCGCTTGTCGGACCAGTACTGGCCACCCAGATGGGTTACTTACCCAGCAGCATCTGGATTGTCGTCGGCGCGGTG
CTGGCCGGATGTGTCCAGGACTACCTGGTGTTGTGGATCTCCGTGCGGCGGCGTGGCCGCTCCCTGGGTCAGATGGTTCG
CGACGAACTCGGCGCCACCGCCGGAGTGGCCGCCCTCGTTGGAATCCCGGTCATTATCACCATTGTGATCGCGGTGCTGG
CGCTGGTGGTCGTGCGGGCCCTGGCCAAGAGCCCATGGGGCGTCTTCTCGATCGCCATGACCATCCCCATCGCCATCTTC
ATGGGCTGCTACTTGCGGTTCCTACGTCCCGGGCGGGTGTCGGAAGTTTCATTGATCGGGATCGGACTGCTGCTGCTCGC
CGTTGTCTCCGGTGATTGGGTTGCCCATACCTCCTGGGGCGCAGCGTGGTTCAGCTTGTCACCGGTGACACTGTGTTGGC
TTCTCATCAGCTATGGCTTCGCAGCTTCGGTGCTGCCGGTGTGGCTGCTGCTCGCGCCACGCGACTACCTGTCAACGTTC
ATGAAGGTCGGCACCATCGCGCTTCTCGCGATCGGTGTTTGTGCGGCTCACCCGATCATCGAGGCCCCAGCGGTGTCGAA
ATTCGCCGGTAGCGGCAACGGCCCGGTGTTCGCCGGCTCACTGTTTCCATTCCTGTTCATCACCATCGCGTGCGGGGCGC
TGTCTGGATTCCACGCGCTCATCTGCTCGGGCACGACGCCGAAGATGCTGGAGAAGGAAGGCCAGATGCGCGTGATCGGC
TACGGCGGCATGATGACCGAGTCCTTCGTCGCCGTCATAGCACTACTCACCGCGGCGATCCTCGACCAGCACCTATACTT
CACCCTCAACGCGCCGTCCCTGCATACCCACGACAGCGCAGCCACCGCCGCCAAGTACGTCAACGGGCTCGGTTTGACGG
GCTCACCGGTGACCCCAGACCACATCAGCCAGGCCGCCGCCAGCGTCGGCGAACAGACGATCGTGTCGCGCACCGGCGGT
GCGCCGACGCTGGCGTTCGGCATGGCGGAGATGCTGCATCGAGTGGTCGGCGGTGTGGGCCTCAAGGCGTTCTGGTATCA
CTTCGCGATCATGTTTGAGGCTCTGTTCATCCTCACCACCGTCGACGCCGGCACCAGGGCCGCGCGCTTCATGATCTCCG
ATGCGCTGGGCAACTTTGGCGGTGTGCTGCGCAAACTGCAGAATCCGAGCTGGCGTCCCGGTGCGTGGGCTTGCCGTTTG
GTGGTCGTCGCGGCGTGGGGCAGCATCCTGCTGCTCGGTGTGACCGATCCGCTGGGCGGCATCAACACGCTGTTCCCGCT
GTTCGGCATTGCCAACCAGTTGCTTGCCGGAATTGCGCTGACCGTCATCACCGTCGTCGTCATCAAGAAGGGGCGACTGA
AGTGGGCTTGGATACCGGGTATTCCACTGCTGTGGGATCTGGCGGTCACCCTGACCGCATCGTGGCAGAAGATCTTCTCC
GCTGATCCTTCTGTCGGCTACTGGACTCAGCATGCTCACTACGCGGCAGCCCAGCACGCAGGCGAGACCGCGTTCGGCTC
GGCCACCAACGCCGATGAGATCAACGACGTCGTCCGGAACACATTCGTCCAGGGCACCCTGTCGATCGTCTTCGTGGTGG
TCGTCGTGCTGGTTGTTGTCGCCGGAGTCATAGTGGCGCTGAAGACAATTCGCGGCCGCGGCATACCGTTGGCCGAGGAC
GATCCGGCGCCGTCGACGTTGTTCGCGCCCGCTGGCCTGATTCCTACAGCCGCAGAGCGAAAGTTGCAACGACGTTTGGG
CGCGCCGGCCTCGGCTTCCGTCGCGGCGCCCGACTAG

Upstream 100 bases:

>100_bases
CCGGCTGGGCGTCGCCAGATTCACGCTCGTCGACCAAGCGGGCGGGACAAGCAGCTGCAAGGATCAACGGAGATCGCACC
CGTGATTGAGGGAGGTGACG

Downstream 100 bases:

>100_bases
CCCTCCCGCTGCAGTGGTACCGGCGCCGCAATCAGACGGCGAGTAGGCGTGGGTCCAACCCGCGATTCGCGGCAGCCGGC
GGAGAGGGCGACCAAGAGAC

Product: carbon starvation protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 758; Mature: 757

Protein sequence:

>758_residues
MAAPTPSNRIEERSGHASCVRADADLPPVAILGRSPITLRHKIFFVAVAVIGALAWTVVAFFRNEPVNAVWIVVAAGCTY
IIGFRFYARLIEMKVVRPRDDHATPAEILDDGTDYVPTDRRVVFGHHFAAIAGAGPLVGPVLATQMGYLPSSIWIVVGAV
LAGCVQDYLVLWISVRRRGRSLGQMVRDELGATAGVAALVGIPVIITIVIAVLALVVVRALAKSPWGVFSIAMTIPIAIF
MGCYLRFLRPGRVSEVSLIGIGLLLLAVVSGDWVAHTSWGAAWFSLSPVTLCWLLISYGFAASVLPVWLLLAPRDYLSTF
MKVGTIALLAIGVCAAHPIIEAPAVSKFAGSGNGPVFAGSLFPFLFITIACGALSGFHALICSGTTPKMLEKEGQMRVIG
YGGMMTESFVAVIALLTAAILDQHLYFTLNAPSLHTHDSAATAAKYVNGLGLTGSPVTPDHISQAAASVGEQTIVSRTGG
APTLAFGMAEMLHRVVGGVGLKAFWYHFAIMFEALFILTTVDAGTRAARFMISDALGNFGGVLRKLQNPSWRPGAWACRL
VVVAAWGSILLLGVTDPLGGINTLFPLFGIANQLLAGIALTVITVVVIKKGRLKWAWIPGIPLLWDLAVTLTASWQKIFS
ADPSVGYWTQHAHYAAAQHAGETAFGSATNADEINDVVRNTFVQGTLSIVFVVVVVLVVVAGVIVALKTIRGRGIPLAED
DPAPSTLFAPAGLIPTAAERKLQRRLGAPASASVAAPD

Sequences:

>Translated_758_residues
MAAPTPSNRIEERSGHASCVRADADLPPVAILGRSPITLRHKIFFVAVAVIGALAWTVVAFFRNEPVNAVWIVVAAGCTY
IIGFRFYARLIEMKVVRPRDDHATPAEILDDGTDYVPTDRRVVFGHHFAAIAGAGPLVGPVLATQMGYLPSSIWIVVGAV
LAGCVQDYLVLWISVRRRGRSLGQMVRDELGATAGVAALVGIPVIITIVIAVLALVVVRALAKSPWGVFSIAMTIPIAIF
MGCYLRFLRPGRVSEVSLIGIGLLLLAVVSGDWVAHTSWGAAWFSLSPVTLCWLLISYGFAASVLPVWLLLAPRDYLSTF
MKVGTIALLAIGVCAAHPIIEAPAVSKFAGSGNGPVFAGSLFPFLFITIACGALSGFHALICSGTTPKMLEKEGQMRVIG
YGGMMTESFVAVIALLTAAILDQHLYFTLNAPSLHTHDSAATAAKYVNGLGLTGSPVTPDHISQAAASVGEQTIVSRTGG
APTLAFGMAEMLHRVVGGVGLKAFWYHFAIMFEALFILTTVDAGTRAARFMISDALGNFGGVLRKLQNPSWRPGAWACRL
VVVAAWGSILLLGVTDPLGGINTLFPLFGIANQLLAGIALTVITVVVIKKGRLKWAWIPGIPLLWDLAVTLTASWQKIFS
ADPSVGYWTQHAHYAAAQHAGETAFGSATNADEINDVVRNTFVQGTLSIVFVVVVVLVVVAGVIVALKTIRGRGIPLAED
DPAPSTLFAPAGLIPTAAERKLQRRLGAPASASVAAPD
>Mature_757_residues
AAPTPSNRIEERSGHASCVRADADLPPVAILGRSPITLRHKIFFVAVAVIGALAWTVVAFFRNEPVNAVWIVVAAGCTYI
IGFRFYARLIEMKVVRPRDDHATPAEILDDGTDYVPTDRRVVFGHHFAAIAGAGPLVGPVLATQMGYLPSSIWIVVGAVL
AGCVQDYLVLWISVRRRGRSLGQMVRDELGATAGVAALVGIPVIITIVIAVLALVVVRALAKSPWGVFSIAMTIPIAIFM
GCYLRFLRPGRVSEVSLIGIGLLLLAVVSGDWVAHTSWGAAWFSLSPVTLCWLLISYGFAASVLPVWLLLAPRDYLSTFM
KVGTIALLAIGVCAAHPIIEAPAVSKFAGSGNGPVFAGSLFPFLFITIACGALSGFHALICSGTTPKMLEKEGQMRVIGY
GGMMTESFVAVIALLTAAILDQHLYFTLNAPSLHTHDSAATAAKYVNGLGLTGSPVTPDHISQAAASVGEQTIVSRTGGA
PTLAFGMAEMLHRVVGGVGLKAFWYHFAIMFEALFILTTVDAGTRAARFMISDALGNFGGVLRKLQNPSWRPGAWACRLV
VVAAWGSILLLGVTDPLGGINTLFPLFGIANQLLAGIALTVITVVVIKKGRLKWAWIPGIPLLWDLAVTLTASWQKIFSA
DPSVGYWTQHAHYAAAQHAGETAFGSATNADEINDVVRNTFVQGTLSIVFVVVVVLVVVAGVIVALKTIRGRGIPLAEDD
PAPSTLFAPAGLIPTAAERKLQRRLGAPASASVAAPD

Specific function: Peptide Utilization During Carbon Starvation. [C]

COG id: COG1966

COG function: function code T; Carbon starvation protein, predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CstA family

Homologues:

Organism=Escherichia coli, GI1786814, Length=706, Percent_Identity=51.5580736543909, Blast_Score=687, Evalue=0.0,
Organism=Escherichia coli, GI87082431, Length=692, Percent_Identity=47.1098265895954, Blast_Score=605, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CSTA_MYCTU (P95095)

Other databases:

- EMBL:   BX842581
- EMBL:   AE000516
- PIR:   H70649
- RefSeq:   NP_217579.1
- RefSeq:   NP_337668.1
- ProteinModelPortal:   P95095
- EnsemblBacteria:   EBMYCT00000003368
- EnsemblBacteria:   EBMYCT00000073048
- GeneID:   887948
- GeneID:   923555
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3149
- KEGG:   mtu:Rv3063
- TIGR:   MT3149
- TubercuList:   Rv3063
- GeneTree:   EBGT00050000016147
- HOGENOM:   HBG304085
- OMA:   ILHPGLY
- ProtClustDB:   CLSK2392987
- InterPro:   IPR003706

Pfam domain/function: PF02554 CstA

EC number: NA

Molecular weight: Translated: 80164; Mature: 80033

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x213280bc)-; HASH(0x20c6b4d4)-; HASH(0x212ab478)-; HASH(0x1fca1bb4)-; HASH(0x210079e4)-; HASH(0x2161639c)-; HASH(0x2156cc48)-; HASH(0x212beb0c)-; HASH(0x210ee07c)-; HASH(0x202d2af4)-; HASH(0x20f968d0)-; HASH(0x20b9dc0c)-; HASH(0x21618eac)-; HASH(0x20ecb204)-; HASH(0x20fbaf18)-; HASH(0x218b33a0)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPTPSNRIEERSGHASCVRADADLPPVAILGRSPITLRHKIFFVAVAVIGALAWTVVA
CCCCCCCCHHHHCCCCCCEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
FFRNEPVNAVWIVVAAGCTYIIGFRFYARLIEMKVVRPRDDHATPAEILDDGTDYVPTDR
HHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCC
RVVFGHHFAAIAGAGPLVGPVLATQMGYLPSSIWIVVGAVLAGCVQDYLVLWISVRRRGR
EEEECCHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGQMVRDELGATAGVAALVGIPVIITIVIAVLALVVVRALAKSPWGVFSIAMTIPIAIF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
MGCYLRFLRPGRVSEVSLIGIGLLLLAVVSGDWVAHTSWGAAWFSLSPVTLCWLLISYGF
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCHHEECCHHHHHHHHHHHHH
AASVLPVWLLLAPRDYLSTFMKVGTIALLAIGVCAAHPIIEAPAVSKFAGSGNGPVFAGS
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEHH
LFPFLFITIACGALSGFHALICSGTTPKMLEKEGQMRVIGYGGMMTESFVAVIALLTAAI
HHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHH
LDQHLYFTLNAPSLHTHDSAATAAKYVNGLGLTGSPVTPDHISQAAASVGEQTIVSRTGG
HCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCC
APTLAFGMAEMLHRVVGGVGLKAFWYHFAIMFEALFILTTVDAGTRAARFMISDALGNFG
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GVLRKLQNPSWRPGAWACRLVVVAAWGSILLLGVTDPLGGINTLFPLFGIANQLLAGIAL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
TVITVVVIKKGRLKWAWIPGIPLLWDLAVTLTASWQKIFSADPSVGYWTQHAHYAAAQHA
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
GETAFGSATNADEINDVVRNTFVQGTLSIVFVVVVVLVVVAGVIVALKTIRGRGIPLAED
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DPAPSTLFAPAGLIPTAAERKLQRRLGAPASASVAAPD
CCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCH
>Mature Secondary Structure 
AAPTPSNRIEERSGHASCVRADADLPPVAILGRSPITLRHKIFFVAVAVIGALAWTVVA
CCCCCCCHHHHCCCCCCEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
FFRNEPVNAVWIVVAAGCTYIIGFRFYARLIEMKVVRPRDDHATPAEILDDGTDYVPTDR
HHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCC
RVVFGHHFAAIAGAGPLVGPVLATQMGYLPSSIWIVVGAVLAGCVQDYLVLWISVRRRGR
EEEECCHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGQMVRDELGATAGVAALVGIPVIITIVIAVLALVVVRALAKSPWGVFSIAMTIPIAIF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
MGCYLRFLRPGRVSEVSLIGIGLLLLAVVSGDWVAHTSWGAAWFSLSPVTLCWLLISYGF
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCHHEECCHHHHHHHHHHHHH
AASVLPVWLLLAPRDYLSTFMKVGTIALLAIGVCAAHPIIEAPAVSKFAGSGNGPVFAGS
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEHH
LFPFLFITIACGALSGFHALICSGTTPKMLEKEGQMRVIGYGGMMTESFVAVIALLTAAI
HHHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHH
LDQHLYFTLNAPSLHTHDSAATAAKYVNGLGLTGSPVTPDHISQAAASVGEQTIVSRTGG
HCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCC
APTLAFGMAEMLHRVVGGVGLKAFWYHFAIMFEALFILTTVDAGTRAARFMISDALGNFG
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GVLRKLQNPSWRPGAWACRLVVVAAWGSILLLGVTDPLGGINTLFPLFGIANQLLAGIAL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
TVITVVVIKKGRLKWAWIPGIPLLWDLAVTLTASWQKIFSADPSVGYWTQHAHYAAAQHA
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
GETAFGSATNADEINDVVRNTFVQGTLSIVFVVVVVLVVVAGVIVALKTIRGRGIPLAED
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DPAPSTLFAPAGLIPTAAERKLQRRLGAPASASVAAPD
CCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036