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The map label for this gene is sucC [H]

Identifier: 148660730

GI number: 148660730

Start: 1063272

End: 1064435

Strand: Direct

Name: sucC [H]

Synonym: MRA_0958

Alternate gene names: 148660730

Gene position: 1063272-1064435 (Clockwise)

Preceding gene: 148660728

Following gene: 148660731

Centisome position: 24.06

GC content: 63.57

Gene sequence:

>1164_bases
ATGGATCTTTTCGAGTATCAAGCCAAGGAGTTATTCGCCAAGCACAACGTGCCCAGCACGCCGGGTCGGGTGACCGACAC
AGCCGAGGGTGCCAAGGCTATCGCCACGGAGATCGGGCGTCCGGTGATGGTCAAAGCGCAGGTCAAGATCGGCGGCCGGG
GCAAGGCCGGTGGCGTCAAATACGCCGCGACCCCACAAGACGCGTACGAGCACGCCAAGAACATCCTCGGCCTGGACATC
AAAGGACACATCGTCAAGAAACTGCTGGTCGCTGAGGCTAGCGATATCGCCGAGGAGTACTACCTATCCTTCCTGCTCGA
CCGGGCCAACCGCACCTACCTGGCGATGTGCTCGGTGGAGGGCGGCATGGAGATCGAAGAGGTAGCGGCCACCAAACCCG
AGCGGCTCGCCAAAGTCCCGGTGAATGCCGTCAAGGGCGTTGACCTAGATTTCGCGCGGTCCATCGCCGAACAGGGTCAT
CTTCCGGCCGAGGTGCTCGACACCGCAGCGGTCACCATCGCCAAGCTGTGGGAGCTCTTCGTCGCCGAGGACGCGACGCT
GGTTGAGGTCAACCCGTTGGTGCGGACGCCTGACCACAAGATCCTCGCGCTGGATGCCAAGATCACCCTCGACGGCAACG
CCGATTTCCGTCAGCCTGGCCATGCCGAGTTCGAGGATCGAGCTGCCACCGATCCACTGGAGTTGAAGGCCAAGGAGCAC
GACCTCAACTACGTCAAGCTGGACGGTCAGGTGGGGATCATCGGCAATGGCGCGGGCTTGGTGATGTCGACTCTCGACGT
CGTCGCGTATGCCGGTGAGAAGCACGGCGGAGTCAAGCCGGCCAACTTCCTGGATATCGGCGGCGGCGCTTCGGCCGAGG
TGATGGCCGCGGGTCTGGACGTGGTGCTGGGCGACCAGCAGGTCAAGAGCGTGTTCGTCAACGTCTTCGGTGGCATCACC
TCGTGCGATGCGGTGGCGACCGGGATCGTCAAGGCGCTGGGCATGCTGGGTGACGAAGCCAACAAGCCGCTGGTGGTTCG
GCTCGACGGCAACAACGTCGAGGAAGGCCGTCGCATCCTGACCGAGGCCAACCACCCCCTGGTGACACTGGTGGCGACGA
TGGACGAAGCCGCCGACAAGGCCGCTGAGCTGGCGAGCGCCTGA

Upstream 100 bases:

>100_bases
AGTTAATCGGCGGTCTCGATACAGTTCTCCGTGCGAGTCGCCGATTTCGGCACCGCCTACCTATTGGTCGAGCAGTAAGC
CGAGCGAAGACGGTGAGCCC

Downstream 100 bases:

>100_bases
GCGAAAGGACCCATGACTCACATGTCCATATTTCTGAGCAGGGACAACAAGGTCATTGTGCAGGGCATCACCGGCAGTGA
GGCCACCGTCCATACCGCGC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MDLFEYQAKELFAKHNVPSTPGRVTDTAEGAKAIATEIGRPVMVKAQVKIGGRGKAGGVKYAATPQDAYEHAKNILGLDI
KGHIVKKLLVAEASDIAEEYYLSFLLDRANRTYLAMCSVEGGMEIEEVAATKPERLAKVPVNAVKGVDLDFARSIAEQGH
LPAEVLDTAAVTIAKLWELFVAEDATLVEVNPLVRTPDHKILALDAKITLDGNADFRQPGHAEFEDRAATDPLELKAKEH
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLDVVLGDQQVKSVFVNVFGGIT
SCDAVATGIVKALGMLGDEANKPLVVRLDGNNVEEGRRILTEANHPLVTLVATMDEAADKAAELASA

Sequences:

>Translated_387_residues
MDLFEYQAKELFAKHNVPSTPGRVTDTAEGAKAIATEIGRPVMVKAQVKIGGRGKAGGVKYAATPQDAYEHAKNILGLDI
KGHIVKKLLVAEASDIAEEYYLSFLLDRANRTYLAMCSVEGGMEIEEVAATKPERLAKVPVNAVKGVDLDFARSIAEQGH
LPAEVLDTAAVTIAKLWELFVAEDATLVEVNPLVRTPDHKILALDAKITLDGNADFRQPGHAEFEDRAATDPLELKAKEH
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLDVVLGDQQVKSVFVNVFGGIT
SCDAVATGIVKALGMLGDEANKPLVVRLDGNNVEEGRRILTEANHPLVTLVATMDEAADKAAELASA
>Mature_387_residues
MDLFEYQAKELFAKHNVPSTPGRVTDTAEGAKAIATEIGRPVMVKAQVKIGGRGKAGGVKYAATPQDAYEHAKNILGLDI
KGHIVKKLLVAEASDIAEEYYLSFLLDRANRTYLAMCSVEGGMEIEEVAATKPERLAKVPVNAVKGVDLDFARSIAEQGH
LPAEVLDTAAVTIAKLWELFVAEDATLVEVNPLVRTPDHKILALDAKITLDGNADFRQPGHAEFEDRAATDPLELKAKEH
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLDVVLGDQQVKSVFVNVFGGIT
SCDAVATGIVKALGMLGDEANKPLVVRLDGNNVEEGRRILTEANHPLVTLVATMDEAADKAAELASA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI157779135, Length=390, Percent_Identity=37.4358974358974, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI11321583, Length=400, Percent_Identity=34.75, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI294862256, Length=370, Percent_Identity=37.8378378378378, Blast_Score=229, Evalue=3e-60,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=41.038961038961, Blast_Score=261, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI17567829, Length=400, Percent_Identity=34.5, Blast_Score=234, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI17539378, Length=398, Percent_Identity=35.1758793969849, Blast_Score=233, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6321683, Length=402, Percent_Identity=37.0646766169154, Blast_Score=248, Evalue=8e-67,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=35.264483627204, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI161078106, Length=402, Percent_Identity=35.8208955223881, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24645208, Length=402, Percent_Identity=35.8208955223881, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI281361397, Length=403, Percent_Identity=35.7320099255583, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI281361395, Length=403, Percent_Identity=35.7320099255583, Blast_Score=223, Evalue=2e-58,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 40926; Mature: 40926

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFEYQAKELFAKHNVPSTPGRVTDTAEGAKAIATEIGRPVMVKAQVKIGGRGKAGGVK
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEE
YAATPQDAYEHAKNILGLDIKGHIVKKLLVAEASDIAEEYYLSFLLDRANRTYLAMCSVE
EECCCHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GGMEIEEVAATKPERLAKVPVNAVKGVDLDFARSIAEQGHLPAEVLDTAAVTIAKLWELF
CCCCHHHHHCCCHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VAEDATLVEVNPLVRTPDHKILALDAKITLDGNADFRQPGHAEFEDRAATDPLELKAKEH
HCCCCEEEEECCCEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHCCCCCCEEEEECC
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLD
CCCEEEECCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHCCCE
VVLGDQQVKSVFVNVFGGITSCDAVATGIVKALGMLGDEANKPLVVRLDGNNVEEGRRIL
EEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHH
TEANHPLVTLVATMDEAADKAAELASA
HCCCCCEEEEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLFEYQAKELFAKHNVPSTPGRVTDTAEGAKAIATEIGRPVMVKAQVKIGGRGKAGGVK
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEE
YAATPQDAYEHAKNILGLDIKGHIVKKLLVAEASDIAEEYYLSFLLDRANRTYLAMCSVE
EECCCHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GGMEIEEVAATKPERLAKVPVNAVKGVDLDFARSIAEQGHLPAEVLDTAAVTIAKLWELF
CCCCHHHHHCCCHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VAEDATLVEVNPLVRTPDHKILALDAKITLDGNADFRQPGHAEFEDRAATDPLELKAKEH
HCCCCEEEEECCCEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCHHCCCCCCEEEEECC
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLD
CCCEEEECCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHCCCE
VVLGDQQVKSVFVNVFGGITSCDAVATGIVKALGMLGDEANKPLVVRLDGNNVEEGRRIL
EEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHH
TEANHPLVTLVATMDEAADKAAELASA
HCCCCCEEEEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]