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The map label for this gene is lpqR [H]

Identifier: 148660615

GI number: 148660615

Start: 936026

End: 936796

Strand: Direct

Name: lpqR [H]

Synonym: MRA_0846

Alternate gene names: 148660615

Gene position: 936026-936796 (Clockwise)

Preceding gene: 148660612

Following gene: 148660616

Centisome position: 21.18

GC content: 68.09

Gene sequence:

>771_bases
GTGCGTCTGATCGGGCGGCTCCGTCTGCTCATGGTGGGGCTGGTCGTCATCTGCGGGGCTTGCGCATGTGACCGCGTGTC
GGCCGGCCGTTGGTCCGAGTCGCCGAGTGCGACCTCGTGGCCCGTCCGGCCGGTAAACACCACAACGCCATCCGGTCCTG
TGCCGCCAGTCAGCGAGGCGGCGCGGGCAGCCGGGTTGGTCGATGTTCGCGGTGTTGTTCCCGATGCCGCCATCGACCTG
CGCTACGCGACGGCGAACAATTTCACCGGCACACAGCTGTACCCGCCCGGGGCAAGATGCCTGGTGCACGAGTCCATGGC
CGAGGGTCTCGCGGCCGCCGCGGCGGTGCTGCGCCCACACGGGCAGGTGCTGGTCTTCTGGGACTGCTATCGGCCCCACG
ACGTTCAGGTCAGGATGTTCGATGTGGTCCCCAACCCGGCCTGGGTGGCGCGGCCGGGCAAGTACGCGCATAGCCATGAG
GCGGGGCGTTCGGTCGATGTGACGTTTGCCAGCGCTCAGCGGCAGTGCCCATCAGTGCGGCGATCCGGCGAATTGTGCCT
GGCCGACATGGGCACCGACTTCGACGACTTTTCTTCGCGGGCGACAGCGTTTGCAACGCAGGGCGTCAGTGCTGAGGCCC
AGGCCAACCGTGCCCACCTGCGAGCCGCCATGCAGGCCGGGGGGTTGACGGTGTACTCCGGTGAGTGGTGGCATTTCGAC
GGCCCCGGCGCCGGCGTCGATCGCCCGATTCTCGAAGTGCCAGTTGACTGA

Upstream 100 bases:

>100_bases
GCGATGGTTGGGTGTGCTCATTTCGGGAACGCCAGGGCGATCAGCGTCGGCAAACTCGCGTCGATGTGCCCGCGGCGCAA
CAATCCGCGACAATGATCGG

Downstream 100 bases:

>100_bases
CGTCTCATATAGTGAAATAAATGTCCACTATTTGGGCGCAGTGGCGGTAGGCTTTGAGCCGAACACCTCGACCATGGGAC
CGCACGGTGAACGACAAACG

Product: D-alanyl-D-alanine dipeptidase

Products: NA

Alternate protein names: D-Ala-D-Ala dipeptidase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MRLIGRLRLLMVGLVVICGACACDRVSAGRWSESPSATSWPVRPVNTTTPSGPVPPVSEAARAAGLVDVRGVVPDAAIDL
RYATANNFTGTQLYPPGARCLVHESMAEGLAAAAAVLRPHGQVLVFWDCYRPHDVQVRMFDVVPNPAWVARPGKYAHSHE
AGRSVDVTFASAQRQCPSVRRSGELCLADMGTDFDDFSSRATAFATQGVSAEAQANRAHLRAAMQAGGLTVYSGEWWHFD
GPGAGVDRPILEVPVD

Sequences:

>Translated_256_residues
MRLIGRLRLLMVGLVVICGACACDRVSAGRWSESPSATSWPVRPVNTTTPSGPVPPVSEAARAAGLVDVRGVVPDAAIDL
RYATANNFTGTQLYPPGARCLVHESMAEGLAAAAAVLRPHGQVLVFWDCYRPHDVQVRMFDVVPNPAWVARPGKYAHSHE
AGRSVDVTFASAQRQCPSVRRSGELCLADMGTDFDDFSSRATAFATQGVSAEAQANRAHLRAAMQAGGLTVYSGEWWHFD
GPGAGVDRPILEVPVD
>Mature_256_residues
MRLIGRLRLLMVGLVVICGACACDRVSAGRWSESPSATSWPVRPVNTTTPSGPVPPVSEAARAAGLVDVRGVVPDAAIDL
RYATANNFTGTQLYPPGARCLVHESMAEGLAAAAAVLRPHGQVLVFWDCYRPHDVQVRMFDVVPNPAWVARPGKYAHSHE
AGRSVDVTFASAQRQCPSVRRSGELCLADMGTDFDDFSSRATAFATQGVSAEAQANRAHLRAAMQAGGLTVYSGEWWHFD
GPGAGVDRPILEVPVD

Specific function: Hydrolyzes D-Ala-D-Ala. May have a role in cell-wall turnover [H]

COG id: COG2173

COG function: function code M; D-alanyl-D-alanine dipeptidase

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15D family [H]

Homologues:

Organism=Escherichia coli, GI1787763, Length=179, Percent_Identity=34.6368715083799, Blast_Score=104, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009045
- InterPro:   IPR000755 [H]

Pfam domain/function: PF01427 Peptidase_M15 [H]

EC number: =3.4.13.22 [H]

Molecular weight: Translated: 27321; Mature: 27321

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIGRLRLLMVGLVVICGACACDRVSAGRWSESPSATSWPVRPVNTTTPSGPVPPVSEA
CCHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
ARAAGLVDVRGVVPDAAIDLRYATANNFTGTQLYPPGARCLVHESMAEGLAAAAAVLRPH
HHHCCCEEECCCCCCCCEEEEEEECCCCCCCEECCCCCHHEEHHHHHHHHHHHHHHHCCC
GQVLVFWDCYRPHDVQVRMFDVVPNPAWVARPGKYAHSHEAGRSVDVTFASAQRQCPSVR
CCEEEEEECCCCCCCEEEEEEECCCCCEEECCCCCCCHHCCCCEEEEEEHHHHHCCHHHH
RSGELCLADMGTDFDDFSSRATAFATQGVSAEAQANRAHLRAAMQAGGLTVYSGEWWHFD
CCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCCEEEEC
GPGAGVDRPILEVPVD
CCCCCCCCCEEECCCC
>Mature Secondary Structure
MRLIGRLRLLMVGLVVICGACACDRVSAGRWSESPSATSWPVRPVNTTTPSGPVPPVSEA
CCHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
ARAAGLVDVRGVVPDAAIDLRYATANNFTGTQLYPPGARCLVHESMAEGLAAAAAVLRPH
HHHCCCEEECCCCCCCCEEEEEEECCCCCCCEECCCCCHHEEHHHHHHHHHHHHHHHCCC
GQVLVFWDCYRPHDVQVRMFDVVPNPAWVARPGKYAHSHEAGRSVDVTFASAQRQCPSVR
CCEEEEEECCCCCCCEEEEEEECCCCCEEECCCCCCCHHCCCCEEEEEEHHHHHCCHHHH
RSGELCLADMGTDFDDFSSRATAFATQGVSAEAQANRAHLRAAMQAGGLTVYSGEWWHFD
CCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEECCCEEEEC
GPGAGVDRPILEVPVD
CCCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]