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The map label for this gene is ychM [C]

Identifier: 148654029

GI number: 148654029

Start: 2772835

End: 2774628

Strand: Direct

Name: ychM [C]

Synonym: PsycPRwf_2232

Alternate gene names: 148654029

Gene position: 2772835-2774628 (Clockwise)

Preceding gene: 148654027

Following gene: 148654030

Centisome position: 93.08

GC content: 49.61

Gene sequence:

>1794_bases
GTGACTGACAAGCCGACCTCACTCATCCCGCACACAAAGCAAGACTGGCTTAAAAAGCTGATTCCCGCTTGGGTTTCAGA
CTATAGCCCCTCTCGCCTACCCGCTGACATTATCGCCGGTATTGTGGTTGGTATCTTGGTCATTCCACAAAGCCTCGGCT
ACGCTGTATTAGCGGGATTGCCCCCTGTGTACGGGCTATATGCCTCAATCGTGCCAGTTTTGGTCTACGCTTGGGTCGGC
TCAAGCAGTGTACAAGCACTCGGCGCCGTTGCCATTACTGCGATCATGACCGCCAGTAGCCTGCATGGTCTGGCAGTTGA
GGGCAGTTTGCAATACATCATGCTTGCCAGCTTATTGGCACTGATGATGGGCGGTATATTATGGCTCGCCGGCAAGCTGA
AGCTTGGCTGGATCATGCAGTTTATTAGCCGCGGGGTATCGGCAGGCTTCGTCAGTGGGGCGGCGGTGCTTATTTTTATT
AGCCAGATAAAATACTTAACCAATATTGCAGTCAGCGGCAACACCTTGCCAGGCTATGCCATCTCCATGTTTAGCCAGTT
AAACAGCTTACATCTGCCCACCTTGCTGATTGGTGCTACCGCTTTTGTTCTGTTTTTATTAAATCGCTATGCCAGTGCTT
ATGTCTGGGAATCTTGGCTACCGCAAGCTCAGGCAAAATGGGCTGGACGATTGTTTCCGCTGCTACTGGTGGTGGTAGCC
ATTGTCTTAAGTTACTTGGGTCAGTGGGCAAGCCGAGGTATTCGCACTATTGGTGAAATCCCAAGCGGCCTACCCAGCTT
CTCTGTGCCTGAATTTGAGTCATTTTCACAAGTTGCCACCTTATTACCCACCGCAGGCTTGATGGCGCTTATTGTGTTTA
TCTCCAGCAGCTCAGTCGCCAGTACCTATGCCCGATTGCGCGGCGAGAAGTTCGATGCCAATACTGAGCTTAGAGGACTG
GGTCTGGCCAATATTGCCGGCGGTTTTAGCCAAAGCTTTCCGGTAGCAGGCGGGTTTTCTCGCACAGCCATCAATGTCGA
TTCTGGTGCTAAGACCCCTTTGGCCAGTGTGGTCAGTGTGGTGGTCATGGTCATCGCGCTATTGTCTTTGAGCCAAATGA
TAGCGCCGCTGCCCTATGCGCTGCTCGGTGCAATGATTATGGCCTCGATTATTAGCCTCATTGACTTTGCCACCTTTAAA
AGCGCTTGGAAAACTGATCGTCTGGATGCATTAAGCTTTTCAGCCACCTTTTTTGGGGTGCTGCTATTTGGGCTTAATGT
GGGCTTGGTCATCGGTATTATTGTCTCTTTTGCTGGCTTGATCTGGCAGTCAAGCCAGCCTCATATCGCCGTAGTAGGCC
GCCTACTAGGCACCGAGCATTTTCGTAACGTAAATCGCCATGATGTGATTACCTACGAGAATTTACTGATTATGCGGGTT
GATGAAAGCTTGTTTTTTGGTAATAGTGAGTCAGTGCATAGCCAAATCCAGCAAGCGCTCAACCACCACCCTAAAGCCTC
TGATTTGGTACTGATTATGTCCTCAGTCAACCACATTGACTTGACGGCACAAGAGATGCTTATCACCTTAAACCGCGAGC
TGGTGGCCAACAATAAGCGTTTGCACTACAGTTTTATTAAGGGGCCGGTGATGGATGTTATAGAACAAACAGCGGTGATT
ACTGAGTTATCTGGACGTGTATTTTTGAGTACCGTTCAGGCCATTAACCTGCTCACCGATGACAATCTTCACAACGACCA
GCACCCTACTGTGCAGCAACAAGAATTTCATTAG

Upstream 100 bases:

>100_bases
TGAAAATAACCGTTACTCATTATCTCAAGCTATCTTGCGCCATCTGTTATATTATACAATTAAGTATATTAACTTATCTC
GCCATCTGTAAGAGGCCACA

Downstream 100 bases:

>100_bases
GCGAATTAAGCACTACCTGGTGTTCAAAACCACGCTAAAATTAACACAAGCCCAAGCTTTGACTGCTCAAAGTCTGTGGC
CTCCATTTACTTTTATTAGA

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MTDKPTSLIPHTKQDWLKKLIPAWVSDYSPSRLPADIIAGIVVGILVIPQSLGYAVLAGLPPVYGLYASIVPVLVYAWVG
SSSVQALGAVAITAIMTASSLHGLAVEGSLQYIMLASLLALMMGGILWLAGKLKLGWIMQFISRGVSAGFVSGAAVLIFI
SQIKYLTNIAVSGNTLPGYAISMFSQLNSLHLPTLLIGATAFVLFLLNRYASAYVWESWLPQAQAKWAGRLFPLLLVVVA
IVLSYLGQWASRGIRTIGEIPSGLPSFSVPEFESFSQVATLLPTAGLMALIVFISSSSVASTYARLRGEKFDANTELRGL
GLANIAGGFSQSFPVAGGFSRTAINVDSGAKTPLASVVSVVVMVIALLSLSQMIAPLPYALLGAMIMASIISLIDFATFK
SAWKTDRLDALSFSATFFGVLLFGLNVGLVIGIIVSFAGLIWQSSQPHIAVVGRLLGTEHFRNVNRHDVITYENLLIMRV
DESLFFGNSESVHSQIQQALNHHPKASDLVLIMSSVNHIDLTAQEMLITLNRELVANNKRLHYSFIKGPVMDVIEQTAVI
TELSGRVFLSTVQAINLLTDDNLHNDQHPTVQQQEFH

Sequences:

>Translated_597_residues
MTDKPTSLIPHTKQDWLKKLIPAWVSDYSPSRLPADIIAGIVVGILVIPQSLGYAVLAGLPPVYGLYASIVPVLVYAWVG
SSSVQALGAVAITAIMTASSLHGLAVEGSLQYIMLASLLALMMGGILWLAGKLKLGWIMQFISRGVSAGFVSGAAVLIFI
SQIKYLTNIAVSGNTLPGYAISMFSQLNSLHLPTLLIGATAFVLFLLNRYASAYVWESWLPQAQAKWAGRLFPLLLVVVA
IVLSYLGQWASRGIRTIGEIPSGLPSFSVPEFESFSQVATLLPTAGLMALIVFISSSSVASTYARLRGEKFDANTELRGL
GLANIAGGFSQSFPVAGGFSRTAINVDSGAKTPLASVVSVVVMVIALLSLSQMIAPLPYALLGAMIMASIISLIDFATFK
SAWKTDRLDALSFSATFFGVLLFGLNVGLVIGIIVSFAGLIWQSSQPHIAVVGRLLGTEHFRNVNRHDVITYENLLIMRV
DESLFFGNSESVHSQIQQALNHHPKASDLVLIMSSVNHIDLTAQEMLITLNRELVANNKRLHYSFIKGPVMDVIEQTAVI
TELSGRVFLSTVQAINLLTDDNLHNDQHPTVQQQEFH
>Mature_596_residues
TDKPTSLIPHTKQDWLKKLIPAWVSDYSPSRLPADIIAGIVVGILVIPQSLGYAVLAGLPPVYGLYASIVPVLVYAWVGS
SSVQALGAVAITAIMTASSLHGLAVEGSLQYIMLASLLALMMGGILWLAGKLKLGWIMQFISRGVSAGFVSGAAVLIFIS
QIKYLTNIAVSGNTLPGYAISMFSQLNSLHLPTLLIGATAFVLFLLNRYASAYVWESWLPQAQAKWAGRLFPLLLVVVAI
VLSYLGQWASRGIRTIGEIPSGLPSFSVPEFESFSQVATLLPTAGLMALIVFISSSSVASTYARLRGEKFDANTELRGLG
LANIAGGFSQSFPVAGGFSRTAINVDSGAKTPLASVVSVVVMVIALLSLSQMIAPLPYALLGAMIMASIISLIDFATFKS
AWKTDRLDALSFSATFFGVLLFGLNVGLVIGIIVSFAGLIWQSSQPHIAVVGRLLGTEHFRNVNRHDVITYENLLIMRVD
ESLFFGNSESVHSQIQQALNHHPKASDLVLIMSSVNHIDLTAQEMLITLNRELVANNKRLHYSFIKGPVMDVIEQTAVIT
ELSGRVFLSTVQAINLLTDDNLHNDQHPTVQQQEFH

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721259, Length=471, Percent_Identity=27.1762208067941, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI94721253, Length=471, Percent_Identity=27.1762208067941, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI94721255, Length=471, Percent_Identity=27.1762208067941, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI94721257, Length=471, Percent_Identity=27.1762208067941, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI4557535, Length=542, Percent_Identity=25.0922509225092, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI45827800, Length=513, Percent_Identity=24.1715399610136, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI39752683, Length=513, Percent_Identity=24.1715399610136, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI45827802, Length=462, Percent_Identity=25.1082251082251, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI47131207, Length=514, Percent_Identity=26.0700389105058, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI20336272, Length=514, Percent_Identity=26.0700389105058, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI16306483, Length=521, Percent_Identity=24.9520153550864, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI269784651, Length=497, Percent_Identity=23.5412474849095, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI20336282, Length=528, Percent_Identity=24.6212121212121, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI100913030, Length=518, Percent_Identity=24.5173745173745, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI4505697, Length=516, Percent_Identity=23.2558139534884, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI16418413, Length=510, Percent_Identity=24.7058823529412, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI217272867, Length=510, Percent_Identity=24.7058823529412, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI16418457, Length=485, Percent_Identity=23.5051546391753, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI301601599, Length=485, Percent_Identity=23.5051546391753, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI262206105, Length=346, Percent_Identity=27.1676300578035, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI262206075, Length=346, Percent_Identity=27.1676300578035, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI262206069, Length=346, Percent_Identity=27.1676300578035, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI262206063, Length=346, Percent_Identity=27.1676300578035, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI301601602, Length=187, Percent_Identity=26.7379679144385, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI45827804, Length=164, Percent_Identity=28.0487804878049, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI87081859, Length=359, Percent_Identity=29.2479108635098, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86564196, Length=528, Percent_Identity=26.5151515151515, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17551690, Length=509, Percent_Identity=25.5402750491159, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI86565215, Length=573, Percent_Identity=24.956369982548, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI193203292, Length=533, Percent_Identity=26.266416510319, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17566848, Length=581, Percent_Identity=25.6454388984509, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17562578, Length=526, Percent_Identity=26.2357414448669, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI86564876, Length=551, Percent_Identity=23.7749546279492, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI86565213, Length=273, Percent_Identity=30.03663003663, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86565209, Length=240, Percent_Identity=23.75, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI86565211, Length=240, Percent_Identity=23.75, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323121, Length=479, Percent_Identity=27.5574112734864, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319771, Length=476, Percent_Identity=26.890756302521, Blast_Score=150, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6325260, Length=575, Percent_Identity=23.4782608695652, Blast_Score=131, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24649801, Length=573, Percent_Identity=28.7958115183246, Blast_Score=198, Evalue=9e-51,
Organism=Drosophila melanogaster, GI19922482, Length=541, Percent_Identity=28.2809611829945, Blast_Score=196, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24663084, Length=559, Percent_Identity=30.2325581395349, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI21357695, Length=559, Percent_Identity=30.2325581395349, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24651449, Length=476, Percent_Identity=26.6806722689076, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI21358229, Length=579, Percent_Identity=27.6338514680484, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI85815873, Length=463, Percent_Identity=29.8056155507559, Blast_Score=168, Evalue=9e-42,
Organism=Drosophila melanogaster, GI21358633, Length=461, Percent_Identity=27.9826464208243, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24666186, Length=649, Percent_Identity=22.8043143297381, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24647160, Length=287, Percent_Identity=25.0871080139373, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21355087, Length=287, Percent_Identity=25.0871080139373, Blast_Score=111, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 64348; Mature: 64217

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS50801 STAS ; PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKPTSLIPHTKQDWLKKLIPAWVSDYSPSRLPADIIAGIVVGILVIPQSLGYAVLAGL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PPVYGLYASIVPVLVYAWVGSSSVQALGAVAITAIMTASSLHGLAVEGSLQYIMLASLLA
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHH
LMMGGILWLAGKLKLGWIMQFISRGVSAGFVSGAAVLIFISQIKYLTNIAVSGNTLPGYA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHH
ISMFSQLNSLHLPTLLIGATAFVLFLLNRYASAYVWESWLPQAQAKWAGRLFPLLLVVVA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IVLSYLGQWASRGIRTIGEIPSGLPSFSVPEFESFSQVATLLPTAGLMALIVFISSSSVA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
STYARLRGEKFDANTELRGLGLANIAGGFSQSFPVAGGFSRTAINVDSGAKTPLASVVSV
HHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHH
VVMVIALLSLSQMIAPLPYALLGAMIMASIISLIDFATFKSAWKTDRLDALSFSATFFGV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LLFGLNVGLVIGIIVSFAGLIWQSSQPHIAVVGRLLGTEHFRNVNRHDVITYENLLIMRV
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEEE
DESLFFGNSESVHSQIQQALNHHPKASDLVLIMSSVNHIDLTAQEMLITLNRELVANNKR
CCHHCCCCCHHHHHHHHHHHHCCCCCCHHEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCE
LHYSFIKGPVMDVIEQTAVITELSGRVFLSTVQAINLLTDDNLHNDQHPTVQQQEFH
EEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDKPTSLIPHTKQDWLKKLIPAWVSDYSPSRLPADIIAGIVVGILVIPQSLGYAVLAGL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PPVYGLYASIVPVLVYAWVGSSSVQALGAVAITAIMTASSLHGLAVEGSLQYIMLASLLA
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHH
LMMGGILWLAGKLKLGWIMQFISRGVSAGFVSGAAVLIFISQIKYLTNIAVSGNTLPGYA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHH
ISMFSQLNSLHLPTLLIGATAFVLFLLNRYASAYVWESWLPQAQAKWAGRLFPLLLVVVA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IVLSYLGQWASRGIRTIGEIPSGLPSFSVPEFESFSQVATLLPTAGLMALIVFISSSSVA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
STYARLRGEKFDANTELRGLGLANIAGGFSQSFPVAGGFSRTAINVDSGAKTPLASVVSV
HHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHH
VVMVIALLSLSQMIAPLPYALLGAMIMASIISLIDFATFKSAWKTDRLDALSFSATFFGV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LLFGLNVGLVIGIIVSFAGLIWQSSQPHIAVVGRLLGTEHFRNVNRHDVITYENLLIMRV
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEEE
DESLFFGNSESVHSQIQQALNHHPKASDLVLIMSSVNHIDLTAQEMLITLNRELVANNKR
CCHHCCCCCHHHHHHHHHHHHCCCCCCHHEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCE
LHYSFIKGPVMDVIEQTAVITELSGRVFLSTVQAINLLTDDNLHNDQHPTVQQQEFH
EEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]