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The map label for this gene is ccmE

Identifier: 148653965

GI number: 148653965

Start: 2704427

End: 2704954

Strand: Direct

Name: ccmE

Synonym: PsycPRwf_2168

Alternate gene names: 148653965

Gene position: 2704427-2704954 (Clockwise)

Preceding gene: 148653964

Following gene: 148653968

Centisome position: 90.78

GC content: 50.0

Gene sequence:

>528_bases
ATGAATGCTGTACGTCGTAAAAAACTGATATGGGTCGCGGCTACTTTAGCAGGCGCTATTATTGCCGTGCTATTGGTCAT
CTACGCCATTGGGCAGCAGACTGACTATTACTTTGACCCGACTGCTATTGCTGCTGGGGACGCACCTCAGAATAAACGCA
TTCGTGCAGGCGGTATGGTGGTGAAAGACAGTGTGCGTCGTGACCCTAACGATGACTTGAAAGTACAGTTTGAGATCACT
GACTTTAATGCCACCGTGCCTGTCAGCTATCAGGGCATCTTACCGGATTTATTTGCAGAAAACTCCGGCGTTGTTGCCAC
AGGAGAGATGCAAGGCAAGGTGTTCGTTGCCAGCGAAGTATTGGCCAAGCACGATGAGAACTATATGCCTCCTGAAGTTG
CCGCCTCGTTAAAAGAAGACCATGCTGCCAAAGGGGTTACGCCCACCTCAGAGCAGTTTAGTCCCGCCATTCCAGTCAAA
CAAACAGCGGGCGAAGGTAACCACACCACAAGCACCTTACAAGAGTAA

Upstream 100 bases:

>100_bases
GCCTGTTTTTTGGTGCATGTTTTTATAATGGCTCAAAAACAGAACCCAACTTTTGCAACAACACTCAATGATTTGAGCGT
ATTAAATAAAAGGCAATCTT

Downstream 100 bases:

>100_bases
TGCGGCCATCTGCTAAGGGCAGATAACTTATCCCAAAAAAAGGCGGAGATAGCAATTATCTCCGCCTTTTTTAACCACTC
ATTTCAGACACCTTAATCTT

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MNAVRRKKLIWVAATLAGAIIAVLLVIYAIGQQTDYYFDPTAIAAGDAPQNKRIRAGGMVVKDSVRRDPNDDLKVQFEIT
DFNATVPVSYQGILPDLFAENSGVVATGEMQGKVFVASEVLAKHDENYMPPEVAASLKEDHAAKGVTPTSEQFSPAIPVK
QTAGEGNHTTSTLQE

Sequences:

>Translated_175_residues
MNAVRRKKLIWVAATLAGAIIAVLLVIYAIGQQTDYYFDPTAIAAGDAPQNKRIRAGGMVVKDSVRRDPNDDLKVQFEIT
DFNATVPVSYQGILPDLFAENSGVVATGEMQGKVFVASEVLAKHDENYMPPEVAASLKEDHAAKGVTPTSEQFSPAIPVK
QTAGEGNHTTSTLQE
>Mature_175_residues
MNAVRRKKLIWVAATLAGAIIAVLLVIYAIGQQTDYYFDPTAIAAGDAPQNKRIRAGGMVVKDSVRRDPNDDLKVQFEIT
DFNATVPVSYQGILPDLFAENSGVVATGEMQGKVFVASEVLAKHDENYMPPEVAASLKEDHAAKGVTPTSEQFSPAIPVK
QTAGEGNHTTSTLQE

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=149, Percent_Identity=48.3221476510067, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME_PSYWF (A5WHG7)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001281058.1
- ProteinModelPortal:   A5WHG7
- SMR:   A5WHG7
- STRING:   A5WHG7
- GeneID:   5204707
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_2168
- eggNOG:   COG2332
- HOGENOM:   HBG296631
- OMA:   ICFCSAC
- ProtClustDB:   PRK13254
- BioCyc:   PSP56811:PSYCPRWF_2168-MONOMER
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 18815; Mature: 18815

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: BINDING 124-124

Signals:

None

Transmembrane regions:

HASH(0x14cebb94)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVRRKKLIWVAATLAGAIIAVLLVIYAIGQQTDYYFDPTAIAAGDAPQNKRIRAGGMV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCCEEECCCEE
VKDSVRRDPNDDLKVQFEITDFNATVPVSYQGILPDLFAENSGVVATGEMQGKVFVASEV
EEHHHCCCCCCCEEEEEEEECCCCCCCEEECCCCHHHHCCCCCEEEECCCCCEEEEHHHH
LAKHDENYMPPEVAASLKEDHAAKGVTPTSEQFSPAIPVKQTAGEGNHTTSTLQE
HHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MNAVRRKKLIWVAATLAGAIIAVLLVIYAIGQQTDYYFDPTAIAAGDAPQNKRIRAGGMV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCCEEECCCEE
VKDSVRRDPNDDLKVQFEITDFNATVPVSYQGILPDLFAENSGVVATGEMQGKVFVASEV
EEHHHCCCCCCCEEEEEEEECCCCCCCEEECCCCHHHHCCCCCEEEECCCCCEEEEHHHH
LAKHDENYMPPEVAASLKEDHAAKGVTPTSEQFSPAIPVKQTAGEGNHTTSTLQE
HHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA