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The map label for this gene is ccmA [H]

Identifier: 148653961

GI number: 148653961

Start: 2701639

End: 2702406

Strand: Direct

Name: ccmA [H]

Synonym: PsycPRwf_2164

Alternate gene names: 148653961

Gene position: 2701639-2702406 (Clockwise)

Preceding gene: 148653958

Following gene: 148653962

Centisome position: 90.69

GC content: 49.35

Gene sequence:

>768_bases
ATGCACCCCACAACCTCGACACATTCAGCTCACATAAATGCCTCTGATAGCCCCTCTACGCCGGTGCTGGTCTTACAAGA
CCTTACCGTACAGCGTGGCGACTTTCCACTGTGTGAAGGGGTGATGCTGCAGCTGTATACTGGCGATATTTGCCATCTTA
TTGGCGCCAACGGTACCGGCAAAACCACGCTATTGATGCAATTGGCCGGACTATTACCGCTGCTTGAAGGCAAGGTGCTG
TATCAAGGCCAAAACAGCTTACCGATAGCGCCTGTCTATGTTTCACATCAATTGGGTATCCATCCAAGCCTCACCGTTAA
GCAAAACCTTAGTTTTTTATTGAACCTGTATGGTATTGAGCCAAGCAATGCTCAAATTGAAGCAGCACTGGACTGGGTCG
GACTGTCAGGGTTTGAGAACATGGGCAGCAATCAGCTCTCAGCGGGTCAAACCCGCCGTGTTACCTTAGCGCGTTTGTAC
CTGATGACGCCACAGCACACGCCTTTGTGGCTATTAGATGAGCCGTTTACGGCATTGGATGTGGCCATGGTGGCACGGTT
GCAGCAGCAATTAAACAGTTTTGTGAACGCAGGCGGCGCGGTATTAATGACCAGTCACCAGCCGGTAGAGGTCGCCAATA
AGCAGCTGGATTTATCTGGTTACCTGCCCTCTTATTCAGGCAGTGATGATTTAGACAGTGATGACAATTTTGCGTCATAT
GCTTATGATGACGATCACTATGACCCTAATAATCAGGGAACACTATGA

Upstream 100 bases:

>100_bases
TATAAGGTCCATTACGCGGCATAAATCACAAGGGATACCCTAAACTCACACTAATGCGTAAGCTTAGTTGTCTGTCCACC
TTTTTATACATCAGGCCACC

Downstream 100 bases:

>100_bases
GCCACAACCCATTAAACCTAAACCAAGCAACTTCTGTCGGTATCAGCACTGCTCGACTATGGCGCCGTGAATGGCAGGTC
AAGCAGCAAGGCGCCGTTCA

Product: heme exporter protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MHPTTSTHSAHINASDSPSTPVLVLQDLTVQRGDFPLCEGVMLQLYTGDICHLIGANGTGKTTLLMQLAGLLPLLEGKVL
YQGQNSLPIAPVYVSHQLGIHPSLTVKQNLSFLLNLYGIEPSNAQIEAALDWVGLSGFENMGSNQLSAGQTRRVTLARLY
LMTPQHTPLWLLDEPFTALDVAMVARLQQQLNSFVNAGGAVLMTSHQPVEVANKQLDLSGYLPSYSGSDDLDSDDNFASY
AYDDDHYDPNNQGTL

Sequences:

>Translated_255_residues
MHPTTSTHSAHINASDSPSTPVLVLQDLTVQRGDFPLCEGVMLQLYTGDICHLIGANGTGKTTLLMQLAGLLPLLEGKVL
YQGQNSLPIAPVYVSHQLGIHPSLTVKQNLSFLLNLYGIEPSNAQIEAALDWVGLSGFENMGSNQLSAGQTRRVTLARLY
LMTPQHTPLWLLDEPFTALDVAMVARLQQQLNSFVNAGGAVLMTSHQPVEVANKQLDLSGYLPSYSGSDDLDSDDNFASY
AYDDDHYDPNNQGTL
>Mature_255_residues
MHPTTSTHSAHINASDSPSTPVLVLQDLTVQRGDFPLCEGVMLQLYTGDICHLIGANGTGKTTLLMQLAGLLPLLEGKVL
YQGQNSLPIAPVYVSHQLGIHPSLTVKQNLSFLLNLYGIEPSNAQIEAALDWVGLSGFENMGSNQLSAGQTRRVTLARLY
LMTPQHTPLWLLDEPFTALDVAMVARLQQQLNSFVNAGGAVLMTSHQPVEVANKQLDLSGYLPSYSGSDDLDSDDNFASY
AYDDDHYDPNNQGTL

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=167, Percent_Identity=29.940119760479, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87082064, Length=201, Percent_Identity=41.7910447761194, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87081791, Length=195, Percent_Identity=31.7948717948718, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1786563, Length=180, Percent_Identity=37.7777777777778, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87081782, Length=198, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87081709, Length=179, Percent_Identity=28.4916201117318, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787792, Length=242, Percent_Identity=25.2066115702479, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790467, Length=197, Percent_Identity=27.9187817258883, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788002, Length=197, Percent_Identity=31.9796954314721, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787370, Length=159, Percent_Identity=30.188679245283, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787712, Length=169, Percent_Identity=28.4023668639053, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI48994943, Length=166, Percent_Identity=29.5180722891566, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786319, Length=183, Percent_Identity=29.5081967213115, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788761, Length=165, Percent_Identity=31.5151515151515, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789032, Length=162, Percent_Identity=29.6296296296296, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082267, Length=169, Percent_Identity=24.2603550295858, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788450, Length=177, Percent_Identity=31.0734463276836, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787500, Length=188, Percent_Identity=27.1276595744681, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788165, Length=190, Percent_Identity=34.2105263157895, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786872, Length=176, Percent_Identity=28.4090909090909, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790739, Length=195, Percent_Identity=30.2564102564103, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 27652; Mature: 27652

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPTTSTHSAHINASDSPSTPVLVLQDLTVQRGDFPLCEGVMLQLYTGDICHLIGANGTG
CCCCCCCCEEEEECCCCCCCCEEEEEECEECCCCCCCHHHEEEEEECCCEEEEECCCCCC
KTTLLMQLAGLLPLLEGKVLYQGQNSLPIAPVYVSHQLGIHPSLTVKQNLSFLLNLYGIE
HHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEEEECCCCCCEEHHHHHHEEEEEECCC
PSNAQIEAALDWVGLSGFENMGSNQLSAGQTRRVTLARLYLMTPQHTPLWLLDEPFTALD
CCCCEEEEEEEEECCCCHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEECCCCHHHH
VAMVARLQQQLNSFVNAGGAVLMTSHQPVEVANKQLDLSGYLPSYSGSDDLDSDDNFASY
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCEEEECCCCCCCCCCCCCCCCCCEEEE
AYDDDHYDPNNQGTL
EECCCCCCCCCCCCC
>Mature Secondary Structure
MHPTTSTHSAHINASDSPSTPVLVLQDLTVQRGDFPLCEGVMLQLYTGDICHLIGANGTG
CCCCCCCCEEEEECCCCCCCCEEEEEECEECCCCCCCHHHEEEEEECCCEEEEECCCCCC
KTTLLMQLAGLLPLLEGKVLYQGQNSLPIAPVYVSHQLGIHPSLTVKQNLSFLLNLYGIE
HHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEEEECCCCCCEEHHHHHHEEEEEECCC
PSNAQIEAALDWVGLSGFENMGSNQLSAGQTRRVTLARLYLMTPQHTPLWLLDEPFTALD
CCCCEEEEEEEEECCCCHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEECCCCHHHH
VAMVARLQQQLNSFVNAGGAVLMTSHQPVEVANKQLDLSGYLPSYSGSDDLDSDDNFASY
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCEEEECCCCCCCCCCCCCCCCCCEEEE
AYDDDHYDPNNQGTL
EECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA